المؤلفون: Graham Duddy, Katherine Courtis, Juliette Horwood, Jessica Olsen, Helen Horsler, Tina Hodgson, Sunita Varsani-Brown, Abdullah Abdullah, Laura Denti, Hollie Lane, Fabio Delaqua, Julia Janzen, Molly Strom, Ian Rosewell, Katharine Crawley, Benjamin Davies

المصدر: BMC Biology, Vol 22, Iss 1, Pp 1-12 (2024)

مصطلحات موضوعية: CRISPR-Cas9, Knock-in mouse, Gene editing, Adeno-associated virus, Zygote, Electroporation, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1741-7007

URL الوصول: https://doaj.org/article/95b5ec7dd7854bb08b37eb55094b38d8

المؤلفون: Bidesh Mahata, Jhuma Pramanik, Louise van der Weyden, Krzysztof Polanski, Gozde Kar, Angela Riedel, Xi Chen, Nuno A. Fonseca, Kousik Kundu, Lia S. Campos, Edward Ryder, Graham Duddy, Izabela Walczak, Klaus Okkenhaug, David J. Adams, Jacqueline D. Shields, Sarah A. Teichmann

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/3d1388c6f86c4110af3e985cacb07322

المؤلفون: Martin Steger, Francesca Tonelli, Genta Ito, Paul Davies, Matthias Trost, Melanie Vetter, Stefanie Wachter, Esben Lorentzen, Graham Duddy, Stephen Wilson, Marco AS Baptista, Brian K Fiske, Matthew J Fell, John A Morrow, Alastair D Reith, Dario R Alessi, Matthias Mann

المصدر: eLife, Vol 5 (2016)

مصطلحات موضوعية: neurodegeneration, phosphoproteomics, LRRK2, rabs, chemical proteomics, parkinson-s disease, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/12813; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/409b18202ccc444788ac40f61b9a7b0c

المؤلفون: Victoria L Newton, Sumia Ali, Graham Duddy, Alan J Whitmarsh, Natalie J Gardiner

المصدر: PLoS ONE, Vol 9, Iss 10, p e107437 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4199525?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/47cb404664bc4db785d05a4d7dc70f58

المؤلفون: Angela Deakin, Graham Duddy, Steve Wilson, Steve Harrison, Judi Latcham, Mick Fulleylove, Sylvia Fung, Jason Smith, Mike Pedrick, Tom McKevitt, Leigh Felton, Joanne Morley, Diana Quint, Dilniya Fattah, Brian Hayes, Jade Gough, Roberto Solari

المصدر: PLoS ONE, Vol 9, Iss 9, p e107490 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4174519?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/d1d949c2f0704f36a96334e7c5b4b83c

المؤلفون: Elif F. Acar, Luis Santos, Graham Duddy, Adam Caulder, Yann Herault, Joshua A. Wood, Jing Zhao, John R. Seavitt, Masaru Tamura, Martin Hrabĕ de Angelis, Gemma F. Codner, Helen Parkinson, Marie-Christine Birling, Lauryl M. J. Nutter, Jason D. Heaney, Radislav Sedlacek, Brandon J. Willis, Susan Marschall, Kevin A. Peterson, Marina Gertsenstein, Alba Gomez-Segura, Allan Bradley, Je Kyung Seong, Lydia Teboul, Kevin C K Lloyd, Fabio Mammano, Jacqueline K. White, Mary E. Dickinson, Francesco Chiani, Matthew Mackenzie, Robert Braun, Isabel Lorenzo, Colin McKerlie, Wolfgang Wurst, Edward Ryder, Cunxiang Ju, Denise G. Lanza, Ruairidh King, Alessia Gambadoro, Ho Lee, Zhiwei Liu, Ramiro Ramirez-Solis, Ann-Marie Mallon, William C. Skarnes, Xiang Gao, Stephen A. Murray, Francesco J. DeMayo, Lauri G. Lintott, Terrence F. Meehan, Fei Zhou, Hannah Wardle-Jones, Shinya Ayabe, Mark T. Ruhe, Atsushi Yoshiki, Brendan Doe, Peter Matthews, Sara Wells, Hillary Elrick, Claudia Seisenberger, David J. Adams, Jie Zhang, Damien Smedley, Petr Kasparek, Daekee Lee, Leslie O. Goodwin

مصطلحات موضوعية: Genetics, Mutant, Null (mathematics), Knockout mouse, Allele, Biology, Null allele, Genome, Gene, Germline

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a11a6fcaf64d723a4f023abdfe162834
https://doi.org/10.1101/2021.10.06.463037

المؤلفون: Klaus Okkenhaug, Edward Ryder, Izabela Walczak, Sarah A. Teichmann, Lia S. Campos, Jacqueline D. Shields, Nuno A. Fonseca, Bidesh Mahata, Angela Riedel, David J. Adams, Xi Chen, Jhuma Pramanik, Krzysztof Polanski, Gozde Kar, Louise van der Weyden, Kousik Kundu, Graham Duddy

المساهمون: Mahata, Bidesh [0000-0002-4506-0184], Polanski, Krzysztof [0000-0002-2586-9576], Chen, Xi [0000-0003-2648-3146], Fonseca, Nuno A [0000-0003-4832-578X], Kundu, Kousik [0000-0002-1019-8351], Ryder, Edward [0000-0002-1799-9899], Okkenhaug, Klaus [0000-0002-9432-4051], Adams, David J [0000-0001-9490-0306], Shields, Jacqueline D [0000-0003-2153-9710], Teichmann, Sarah A [0000-0002-6294-6366], Apollo - University of Cambridge Repository, Fonseca, Nuno A. [0000-0003-4832-578X], Adams, David J. [0000-0001-9490-0306], Shields, Jacqueline D. [0000-0003-2153-9710], Teichmann, Sarah A. [0000-0002-6294-6366]

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
bioRxiv

مصطلحات موضوعية: 0301 basic medicine, CD4-Positive T-Lymphocytes, medicine.medical_treatment, animal diseases, Druggability, General Physics and Astronomy, Transcriptome, 13/1, Mice, 0302 clinical medicine, lcsh:Science, Melanoma, Mice, Knockout, 0303 health sciences, Multidisciplinary, article, Immunosuppression, Primary tumor, 3. Good health, Cell biology, 13/31, medicine.anatomical_structure, 030220 oncology & carcinogenesis, 9, 38/77, Tumour immunology, 64/60, Steroids, 631/67/327, Cancer microenvironment, Science, Transgene, T cell, 13/106, chemical and pharmacologic phenomena, Steroid biosynthesis, Biology, General Biochemistry, Genetics and Molecular Biology, 38, 38/91, 03 medical and health sciences, Immune system, 13/21, Immunity, Cell Line, Tumor, medicine, Animals, Humans, Cholesterol Side-Chain Cleavage Enzyme, 030304 developmental biology, Immune Evasion, General Chemistry, biochemical phenomena, metabolism, and nutrition, medicine.disease, 030104 developmental biology, Cell culture, 631/67/580, Cancer cell, Cancer research, bacteria, lcsh:Q

وصف الملف: application/pdf; text/xml; application/zip

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f11aa4b3c8b61151e053e9deb0002f2f
https://www.repository.cam.ac.uk/handle/1810/308612

المؤلفون: Natalia Shpiro, Pawel Lis, Philip Wing-Lok Ho, Genta Ito, Graham Duddy, Steve Wilson, Francesca Tonelli, Kristina Katsemonova, Marco A. S. Baptista, Alastair D. Reith, Dario R. Alessi, Shu-Leong Ho

المصدر: Biochemical Journal

مصطلحات موضوعية: 0301 basic medicine, Parkinson's disease, Endogeny, GTPase, Biology, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Biochemistry, Mice, 03 medical and health sciences, In vivo, Commentaries, Humans, Animals, Phosphorylation, Protein Kinase Inhibitors, Molecular Biology, Research Articles, Mice, Knockout, Kinase, LRRK2, Cell Biology, Molecular biology, Hedgehog signaling pathway, nervous system diseases, inhibitor, Protein Transport, 030104 developmental biology, rab GTP-Binding Proteins, Rab10, Commentary, Phos-tag, Rab, Protein Kinases, Rab GTPase, signal transduction, knockout mice, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73c43cbd69e798aada8f4d4004c3094
https://doi.org/10.1042/bcj20160557

المؤلفون: Aristi Damaskou, Eshwar Meduri, Malgorzata Gozdecka, Brian J. P. Huntly, Milena Mazan, Konstantinos Tzelepis, Graham Duddy, Vijay Baskar, Penny Wright, Kosuke Yusa, George S. Vassiliou, Monika Dudek

المصدر: Blood. 134:111-111

مصطلحات موضوعية: Mutation, IDH1, Methyltransferase, Methyltransferase complex, Immunology, Mutant, Cell Biology, Hematology, Biology, medicine.disease_cause, Biochemistry, Molecular biology, Haematopoiesis, medicine, H3K4me3, Gene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2aa55744bd1e1c9af37615abbd0333ca
https://doi.org/10.1182/blood-2019-126505

المؤلفون: Xi Chen, Johan Henriksson, Kerstin B. Meyer, Ricardo J. Miragaia, Sarah A. Teichmann, Riitta Lahesmaa, Tomás Gomes, Kosuke Yusa, Graham Duddy, Jhuma Pramanik, Ubaid Ullah

المصدر: bioRxiv
Cell

مصطلحات موضوعية: ATAC-seq, Biology, Lymphocyte Activation, ta3111, General Biochemistry, Genetics and Molecular Biology, Novel gene, Mice, 03 medical and health sciences, Th2 Cells, 0302 clinical medicine, Animals, Humans, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, ta318, natural sciences, Receptor, Transcription factor, Gene, 030304 developmental biology, Genetics, 0303 health sciences, Genome, Cas9, High-Throughput Nucleotide Sequencing, Cell Differentiation, Receptor Cross-Talk, T-Lymphocytes, Helper-Inducer, Acquired immune system, Chromatin, CD4 T helper cell, mouse, Cas9, CRISPR, pooled screen, library, retrovirus, knock-out, overexpression, ATAC-seq, ChIP-seq, time-course, overexpression, 3. Good health, Cell biology, Mice, Inbred C57BL, Crosstalk (biology), T-helper cell type 2, 030220 oncology & carcinogenesis, CRISPR-Cas Systems, Cell activation, 030217 neurology & neurosurgery, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82163d86144ffec0f6efb666822479af
https://doi.org/10.1016/j.cell.2018.11.044