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1
المؤلفون: Paul W. Smith, Ian Thomson Forbes, Andrea M. Bradford, Graham Walker, Graham Murkitt, Wyman Paul Adrian, Graeme Irvine Stevenson, Dale James Johnson, Jeannette M. Watson, Steve P. Watson, Adam J. Lucas, Claudette Mookherjee, Fiona Brown, Vincenzo Garzya, Sean Thomas Flynn, Jane Gartlon, Harminder Mudhar
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:5434-5438
مصطلحات موضوعية: Agonist, Indoles, medicine.drug_class, Stereochemistry, education, Clinical Biochemistry, Allosteric regulation, Pharmaceutical Science, Muscarinic Agonists, Biochemistry, Chemical synthesis, chemistry.chemical_compound, Drug Discovery, Muscarinic acetylcholine receptor, medicine, Animals, Molecular Biology, Nootropic Agents, Benzoxazoles, Memory Disorders, Bicyclic molecule, Receptor, Muscarinic M1, Organic Chemistry, Brain, Oxindoles, Rats, chemistry, Lipophilicity, Lactam, Molecular Medicine, Penetrant (biochemical)
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2
المؤلفون: Christopher J. Langmead, Jim J. Hagan, Paul W. Smith, Mark Hill, Graham Murkitt, Jeannette M. Watson, Ceri H. Davies, Adeshola Dada, Zining Wu, Gareth A. Jones, Lee A. Dawson, Eric Southam, Declan N.C. Jones, Jane E. Cluderay, Raul de la Flor
المصدر: European Journal of Pharmacology. 627:106-114
مصطلحات موضوعية: Male, medicine.medical_specialty, Neurokinin B, Dopamine, Inositol Phosphates, Microdialysis, Guinea Pigs, Substance P, Biology, Nucleus Accumbens, Guinea pig, chemistry.chemical_compound, In vivo, Internal medicine, medicine, Animals, Humans, Cloning, Molecular, Neurotransmitter, Receptor, Receptors, Tachykinin, Cerebral Cortex, Neurons, Pharmacology, Habenula, Behavior, Animal, Antagonist, Brain, Peptide Fragments, Rats, Endocrinology, chemistry, Competitive antagonist, Aminoquinolines, Quinolines, Haloperidol, Extracellular Space, Peptides, Ex vivo, medicine.drug
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3
المؤلفون: Jane Gartlon, Richard Foxton, Darrel J. Pemberton, Ceri H. Davies, Jane E. Cluderay, Lee A. Dawson, Martyn D. Wood, Eric Southam, Gareth A. Jones, Jim J. Hagan, Jeannette M. Watson, Claire M. Scott, Graham Murkitt, Declan N.C. Jones, Raul de la Flor, James N.C. Kew, Katherine J. Cato
المصدر: Neuropsychopharmacology. 33:1642-1652
مصطلحات موضوعية: Male, Agonist, medicine.medical_specialty, medicine.drug_class, Dopamine, Guinea Pigs, Substantia nigra, In Vitro Techniques, Nucleus accumbens, Biology, chemistry.chemical_compound, Cell Line, Tumor, Internal medicine, Talnetant, medicine, Animals, Humans, Receptor, Neurotransmitter, Cell Line, Transformed, Neurons, Pharmacology, Neurotransmitter Agents, Dose-Response Relationship, Drug, Brain, Receptors, Neurokinin-3, Psychiatry and Mental health, Endocrinology, chemistry, Quinolines, Calcium, Neurokinin B, Protein Binding, medicine.drug
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4
المؤلفون: Lee Andrew Harrison, Michael Dennis Dowle, Harry Finch, Robin Andrew Smith, Pritom Shah, K.Abhhilash Kumar, Gill Fleetwood, Simon Teanby Hodgson, George W. Hardy, Graham Murkitt, Simon J. F. Macdonald, Graham G. A. Inglis, Christopher R Molloy, Geoffrey D. Clarke, Augustin Amour, Rosalind E Godward, Tony Padfield, Davina Humphreys, M. R. Johnson, Mary Dixon, Tadeusz Skarzynski, Onkar M. P. Singh
المصدر: Bioorganic & Medicinal Chemistry Letters. 11:895-898
مصطلحات موضوعية: Lactams, Human neutrophil, Metabolic Clearance Rate, Clinical Biochemistry, Administration, Oral, Biological Availability, Pharmaceutical Science, Pharmacology, Biochemistry, Dogs, Drug Stability, Piperidines, Pharmacokinetics, Cricetinae, Drug Discovery, Animals, Molecular Biology, Short duration, Serpins, Bacteria, Pancreatic Elastase, Chemistry, Serine Endopeptidases, Organic Chemistry, Elastase, Bacterial Infections, Rats, Bioavailability, Orally active, Pharmacodynamics, Molecular Medicine, Crystallization, Leukocyte Elastase, Intracellular
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5
المؤلفون: Paul W. Smith, Caroline J. Goodacre, Wyman Paul Adrian, Sara A. Coggon, Vong Antonio Kuok Keong, Jeannette M. Watson, William J. Martin, Kirsten L. Searle, Daniel Marcus Bradley, Zining Wu, Peter J. Lovell, Lee A. Dawson, Harrington Frank Peter, David R. Thomas, Roderick A. Porter, Graham Murkitt, Halina T Serafinowska, Sean Thomas Flynn
المصدر: Bioorganicmedicinal chemistry letters. 19(3)
مصطلحات موضوعية: Central Nervous System, Male, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Gerbil, Biochemistry, Rats, Sprague-Dawley, chemistry.chemical_compound, In vivo, Drug Discovery, Talnetant, medicine, Animals, Amines, Molecular Biology, Cerebral Cortex, Chemistry, Organic Chemistry, Quinoline, Antagonist, Brain, Receptors, Neurokinin-3, Rats, Models, Chemical, Area Under Curve, Lipophilicity, Quinolines, Molecular Medicine, Gerbillinae, Ex vivo, medicine.drug
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6
المؤلفون: Christopher R Molloy, Simon Teanby Hodgson, Robin A.J. Smith, Tadeusz Skarzynski, Onkar M. P. Singh, Rosalind E Godward, Julie E. Spooner, Harry Finch, Mary Dixon, K.Abhhilash Kumar, David J. Belton, Graham G. A. Inglis, Pritom Shah, Simon J. F. Macdonald, Graham Murkitt, Martin R. Johnson, Edward McDonald, Lee Andrew Harrison, Davina Humphreys, Gill Fleetwood, Geoffrey D. Clarke, George W. Hardy, Michael Dennis Dowle
المصدر: Bioorganic & Medicinal Chemistry Letters. 11:1249
مصطلحات موضوعية: Human neutrophil, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Elastase, Pharmaceutical Science, Biochemistry, Pyrrolidine, chemistry.chemical_compound, Orally active, chemistry, Drug Discovery, Molecular Medicine, Theology, Molecular Biology