نتائج البحث - "Graham R. Campbell"

1

دورية أكاديمية

Mitochondria as Crucial Players in Demyelinated Axons: Lessons from Neuropathology and Experimental Demyelination

المؤلفون: Graham R. Campbell, Don J. Mahad

المصدر: Autoimmune Diseases, Vol 2011 (2011)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2090-0430

URL الوصول: https://doaj.org/article/2fbf8a0afad34c578fa072961dd48fa0

View record at Wiley

Full Text Finder

2

The role of complex IV activity in the axonal response of mitochondria to demyelination in experimental disease models of multiple sclerosis

مصطلحات موضوعية: business.industry, Mitochondrial respiratory chain complex IV, Multiple sclerosis, Experimental autoimmune encephalomyelitis, Cell, Disease, Mitochondrion, medicine.disease, Neuroprotection, medicine.anatomical_structure, nervous system, medicine, Axon, business, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5d200d032d9cb001e6fcf387053783b5
https://doi.org/10.1101/2021.09.27.461926

3

Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis

المساهمون: Apollo - University of Cambridge Repository, Translational Immunology Groningen (TRIGR), Molecular Neuroscience and Ageing Research (MOLAR), Franklin, Robin [0000-0001-6522-2104]

المصدر: Licht-Mayer, S, Campbell, G R, Canizares, M, Mehta, A R, Gane, A B, McGill, K, Ghosh, A, Fullerton, A, Menezes, N, Dean, J, Dunham, J, Al-Azki, S, Pryce, G, Zandee, S, Zhao, C, Kipp, M, Smith, K J, Baker, D, Altmann, D, Anderton, S M, Kap, Y S, Laman, J D, Hart, B A, Rodriguez, M, Watzlawick, R, Schwab, J M, Carter, R, Morton, N, Zagnoni, M, Franklin, R J M, Mitchell, R, Fleetwood-Walker, S, Lyons, D A, Chandran, S, Lassmann, H, Trapp, B D & Mahad, D J 2020, ' Enhanced axonal response of mitochondria to demyelination offers neuroprotection : Implications for multiple sclerosis ', Acta Neuropathologica, vol. 140, no. 2, pp. 143–167 . https://doi.org/10.1007/s00401-020-02179-x
Acta Neuropathologica
Acta Neuropathologica, 140(2), 143-167. SPRINGER

مصطلحات موضوعية: TK, PGC-1-ALPHA, Axonal loss, Biology, Mitochondrion, RAPID ISOLATION, MOUSE, Neuroprotection, Pathology and Forensic Medicine, GENE DELETION, Multiple sclerosis, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, DNA DELETIONS, medicine, Animals, Humans, Axon, Demyelinating Disorder, Mitochondrial transport, 030304 developmental biology, 0303 health sciences, Original Paper, Organelle Biogenesis, RECEPTOR, Demyelination and neuroprotection, medicine.disease, Axons, TRANSPORT, humanities, PHOSPHOLIPASE-D, 3. Good health, Mitochondria, medicine.anatomical_structure, Mitochondrial biogenesis, nervous system, EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS, Nerve Degeneration, Neurology (clinical), MYELINATION, Neuroscience, 030217 neurology & neurosurgery, Demyelinating Diseases

وصف الملف: application/zip; text/xml; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e4693411de7b84ffffa08f0cedcee1
https://www.repository.cam.ac.uk/handle/1810/307933

Find this article in full text from Springer Verlag.

Find this article in full text from ProQuest

4

Mitochondrial dysfunction and axon degeneration in progressive multiple sclerosis

المؤلفون: Don J. Mahad, Graham R. Campbell

المصدر: Campbell, G & Mahad, D 2018, ' Mitochondrial dysfunction and axon degeneration in progressive multiple sclerosis ', FEBS Letters . https://doi.org/10.1002/1873-3468.13013

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e23fb8e191268586579cca7d0119ae27
https://doi.org/10.1002/1873-3468.13013

View record at Wiley

5

Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects

المساهمون: Biochemie, RS: FHML MaCSBio, RS: CARIM - R1 - Thrombosis and haemostasis, RS: Carim - B01 Blood proteins & engineering, University Hospital Münster - Universitaetsklinikum Muenster [Germany] (UKM), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), University of Edinburgh, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University [Maastricht], Sanofi Genzyme, Perelman School of Medicine, University of Pennsylvania, The University of Sydney, Pistre, Karine

المصدر: Klotz, L, Eschborn, M, Lindner, M, Liebmann, M, Herold, M, Janoschka, C, Torres Garrido, B, Schulte-Mecklenbeck, A, Gross, C C, Breuer, J, Hundehege, P, Posevitz, V, Pignolet, B, Nebel, G, Glander, S, Freise, N, Austermann, J, Wirth, T, Campbell, G R, Schneider-Hohendorf, T, Eveslage, M, Brassat, D, Schwab, N, Loser, K, Roth, J, Busch, K B, Stoll, M, Mahad, D J, Meuth, S G, Turner, T, Bar-Or, A & Wiendl, H 2019, ' Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects ', Science Translational Medicine, vol. 11, no. 490, eaao5563 . https://doi.org/10.1126/scitranslmed.aao5563
Science Translational Medicine, 11(490):5563. American Association for the Advancement of Science
Science Translational Medicine
Science Translational Medicine, 2019, 11 (490), ⟨10.1126/scitranslmed.aao5563⟩

مصطلحات موضوعية: MESH: Dihydroorotate Dehydrogenase, [SDV]Life Sciences [q-bio], T-Lymphocytes, Respiratory chain, Dihydroorotate Dehydrogenase, Hydroxybutyrates, Lymphocyte Activation, MESH: Electron Transport Complex III / metabolism, Oxidative Phosphorylation, chemistry.chemical_compound, Electron Transport Complex III, LEFLUNOMIDE, Teriflunomide, MESH: Animals, MESH: Hydroxybutyrates, Chemistry, MESH: Gene Expression Regulation / drug effects, MESH: Aerobiosis / drug effects, General Medicine, Aerobiosis, Cell biology, Mitochondria, [SDV] Life Sciences [q-bio], medicine.anatomical_structure, MESH: Crotonates / pharmacology, Crotonates, Pyrimidine metabolism, [SDV.IMM]Life Sciences [q-bio]/Immunology, Glycolysis, TCR, Oxidoreductases Acting on CH-CH Group Donors, Multiple Sclerosis, [SDV.IMM] Life Sciences [q-bio]/Immunology, AVIDITY MATURATION, Toluidines, T cell, Cell Respiration, Receptors, Antigen, T-Cell, MESH: Cell Proliferation / drug effects, MESH: Crotonates / therapeutic use, Immune system, Multiple Sclerosis, Relapsing-Remitting, Antigen, Nitriles, medicine, Animals, Humans, MESH: Glycolysis / drug effects, NEGATIVE SELECTION, Cell Proliferation, MESH: Lymphocyte Subsets / immunology, MESH: Cell Respiration / drug effects, MESH: Humans, Cell growth, MESH: Mitochondria / drug effects, MESH: Lymphocyte Activation / drug effects, Lymphocyte Subsets, MESH: Lymphocyte Subsets / drug effects, RHEUMATOID-ARTHRITIS, MESH: Mitochondria / metabolism, Gene Expression Regulation, Dihydroorotate dehydrogenase, Energy Metabolism, MESH: Energy Metabolism / drug effects

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c6a6928d973af7c45bf548e65e0113
https://hdl.handle.net/20.500.11820/c76c0dcd-4614-4fdc-92e3-04332843a83f

6

A Method to Detect Cytochrome c Oxidase Activity and Mitochondrial Proteins in Oligodendrocytes

المؤلفون: Graham R, Campbell, Don J, Mahad

المصدر: Methods in molecular biology (Clifton, N.J.). 1936

مصطلحات موضوعية: Central Nervous System, Electron Transport Complex IV, Mitochondrial Proteins, Oligodendroglia, Animals, Humans, Single-Cell Analysis, Immunohistochemistry, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::ca2f6e223a708fc4cb95d84842dde034
https://pubmed.ncbi.nlm.nih.gov/30820908

7

A targeted mutation disrupting mitochondrial complex IV function in primary afferent neurons leads to pain hypersensitivity through P2Y1 receptor activation

المؤلفون: Susan M. Fleetwood-Walker, Katie McGill, Rory Mitchell, Graham R. Campbell, Don J. Mahad, Marta Mikolajczak

المصدر: Mitchell, R, Campbell, G, Mikolajczak, M, McGill, K, Mahad, D & Fleetwood-Walker, S 2019, ' A targeted mutation disrupting mitochondrial complex IV function in primary afferent neurons leads to pain hypersensitivity through P2Y1 receptor activation. ', Molecular Neurobiology . https://doi.org/10.1007/s12035-018-1455-4