المؤلفون: Granato JDT; Departamento de Parasitologia, Microbiologia e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil., Silva ETD; Fundação Oswaldo Cruz (Fiocruz), Instituto de Tecnologia em Fármacos Farmanguinhos, Rio de Janeiro, Brazil., Lemos ASO; Departamento de Parasitologia, Microbiologia e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil., Machado PA; Laboratório de Biologia Estrutural, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil., Midlej VDV; Laboratório de Biologia Estrutural, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil., Antinarelli LMR; Departamento de Parasitologia, Microbiologia e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil., Silva Neto AFD; Departamento de Medicina Veterinária, Faculdade de Medicina, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil., Souza MVN; Fundação Oswaldo Cruz (Fiocruz), Instituto de Tecnologia em Fármacos Farmanguinhos, Rio de Janeiro, Brazil., Coimbra ES; Departamento de Parasitologia, Microbiologia e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.

المصدر: Chemical biology & drug design [Chem Biol Drug Des] 2024 May; Vol. 103 (5), pp. e14535.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print Cited Medium: Internet ISSN: 1747-0285 (Electronic) Linking ISSN: 17470277 NLM ISO Abbreviation: Chem Biol Drug Des Subsets: MEDLINE

مواضيع طبية MeSH: Mice, Inbred BALB C* , Apoptosis*/drug effects , Mitochondria*/drug effects , Mitochondria*/metabolism , Hydrazones*/pharmacology , Hydrazones*/chemistry , Leishmaniasis, Cutaneous*/drug therapy , Leishmaniasis, Cutaneous*/parasitology, Animals ; Mice ; Antiprotozoal Agents/pharmacology ; Antiprotozoal Agents/chemistry ; Antiprotozoal Agents/therapeutic use ; Leishmania/drug effects ; Reactive Oxygen Species/metabolism ; Female ; Leishmania mexicana/drug effects ; Membrane Potential, Mitochondrial/drug effects

المؤلفون: Lemos ASO; Bioactive Natural Products Laboratory, Department of Biochemistry, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Campos LM; Bioactive Natural Products Laboratory, Department of Biochemistry, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Granato JDT; Department of Parasitology, Microbiology, and Immunology, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Goliatt PVZC; Department of Computer Science, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Dib PRB; Laboratory of Immunothrombosis, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Hottz ED; Laboratory of Immunothrombosis, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Glanzmann N; Department of Chemistry, Institute of Exact Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Campos LC; Laboratory of Cellular Biology, Department of Biology, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Bizarro HDS; Laboratory of Cellular Biology, Department of Biology, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Chedier LM; Plant Chemistry Laboratory, Department of Botany, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Coimbra ES; Department of Parasitology, Microbiology, and Immunology, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Fabri RL; Bioactive Natural Products Laboratory, Department of Biochemistry, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, Brazil.

المصدر: The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2023 Oct 05; Vol. 75 (10), pp. 1388-1393.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0376363 Publication Model: Print Cited Medium: Internet ISSN: 2042-7158 (Electronic) Linking ISSN: 00223573 NLM ISO Abbreviation: J Pharm Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Dinoprostone*/metabolism , Lipopolysaccharides*/pharmacology, Animals ; Mice ; Cyclooxygenase 2/metabolism ; Reactive Oxygen Species/metabolism ; Lipid Metabolism ; Molecular Docking Simulation ; Interferon-gamma/metabolism ; Transforming Growth Factor beta/metabolism

المؤلفون: Lemos ASO; Bioactive Natural Products Laboratory, Department of Biochemistry, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil.; Postgraduate Program in Biological Sciences, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil., Campos LM; Bioactive Natural Products Laboratory, Department of Biochemistry, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil., Souza TF; Bioactive Natural Products Laboratory, Department of Biochemistry, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil., Paula PL; Bioactive Natural Products Laboratory, Department of Biochemistry, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil., Granato JDT; Department of Parasitology, Microbiology, and Immunology, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil.; Postgraduate Program in Biological Sciences, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil., da Silva JVG; Postgraduate Program in Biological Sciences, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil., Aragão DMO; Bioactive Natural Products Laboratory, Department of Biochemistry, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil., Rocha VN; Department of Veterinary Medicine, Faculty of Medicine, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil., Coimbra ES; Department of Parasitology, Microbiology, and Immunology, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil.; Postgraduate Program in Biological Sciences, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil., Fabri RL; Bioactive Natural Products Laboratory, Department of Biochemistry, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil.; Postgraduate Program in Biological Sciences, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil.

المصدر: The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2022 May 20; Vol. 74 (5), pp. 750-760.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0376363 Publication Model: Print Cited Medium: Internet ISSN: 2042-7158 (Electronic) Linking ISSN: 00223573 NLM ISO Abbreviation: J Pharm Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Rubiaceae*/chemistry, Anti-Inflammatory Agents/therapeutic use ; Antioxidants/chemistry ; Edema/chemically induced ; Edema/drug therapy ; Humans ; Phenols/pharmacology ; Plant Extracts/chemistry ; Quercetin

المؤلفون: Tavares GSV; Post-graduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, Medicine School, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Mendonça DVC; Post-graduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, Medicine School, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Lage DP; Post-graduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, Medicine School, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Granato JDT; Department of Parasitology, Microbiology and Immunology, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil., Ottoni FM; Department of Pharmaceutical Products, Pharmacy School, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Ludolf F; Post-graduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, Medicine School, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Chávez-Fumagalli MA; Post-graduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, Medicine School, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Duarte MC; Post-graduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, Medicine School, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Tavares CAP; Department of Biochemistry and Immunology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Alves RJ; Department of Pharmaceutical Products, Pharmacy School, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Coimbra ES; Department of Parasitology, Microbiology and Immunology, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil., Coelho EAF; Post-graduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, Medicine School, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

المصدر: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2018 Sep; Vol. 123 (3), pp. 236-246. Date of Electronic Publication: 2018 Apr 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843 (Electronic) Linking ISSN: 17427835 NLM ISO Abbreviation: Basic Clin Pharmacol Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Antiprotozoal Agents/*pharmacology , Clioquinol/*pharmacology , Leishmania infantum/*drug effects , Leishmania mexicana/*drug effects, Animals ; Antiprotozoal Agents/administration & dosage ; Clioquinol/administration & dosage ; Erythrocytes/drug effects ; Female ; Humans ; Leishmaniasis/drug therapy ; Leishmaniasis/parasitology ; Macrophages/metabolism ; Macrophages/parasitology ; Membrane Potential, Mitochondrial/drug effects ; Mice ; Mice, Inbred BALB C ; Mitochondria/drug effects ; Mitochondria/parasitology ; Reactive Oxygen Species/metabolism