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1
المؤلفون: Jordan L. Pederick, Birgit I Gaiser, Nicholas C Schumann, Kate L. Wegener, Kwangjun Lee, James Hodgkinson-Bean, Steven W. Polyak, Thomas D. Avery, Grant W. Booker, John B. Bruning, Andrew D. Abell, Wanisa Salaemae, Andrew P. Thompson
المصدر: ACS Chemical Biology. 16:2339-2347
مصطلحات موضوعية: Tuberculosis, In silico, 01 natural sciences, Biochemistry, Dethiobiotin synthase, Mycobacterium tuberculosis, 03 medical and health sciences, chemistry.chemical_compound, Biotin, Biosynthesis, medicine, Tetrazole, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, biology, 010405 organic chemistry, General Medicine, medicine.disease, biology.organism_classification, 0104 chemical sciences, 3. Good health, Enzyme, chemistry, biology.protein, Molecular Medicine
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2دورية أكاديمية
المؤلفون: Andrew J. Hayes, Jiulia Satiaputra, Louise M. Sternicki, Ashleigh S. Paparella, Zikai Feng, Kwang J. Lee, Beatriz Blanco-Rodriguez, William Tieu, Bart A. Eijkelkamp, Keith E. Shearwin, Tara L. Pukala, Andrew D. Abell, Grant W. Booker, Steven W. Polyak
المصدر: Antibiotics, Vol 9, Iss 4, p 165 (2020)
مصطلحات موضوعية: antimicrobial resistance, Gram-positive bacteria, Staphylococcus aureus, advanced resistance studies, biotin, biotin protein ligase, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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3
المؤلفون: Kwangjun Lee, Andrew D. Abell, Steven W. Polyak, Beatriz Blanco-Rodriguez, John B. Bruning, Danielle Cini, Grant W. Booker, Robert W. Milne, Benjamin Noll, Andrew J. Hayes, Andrew C Marshall, Ashleigh S. Paparella, Jiage Feng, Matthew C.J. Wilce, Jingxian Yu, William Tieu
المساهمون: Lee, Kwang Jun, Tieu, William, Blanco-Rodriguez, Beatriz, Paparella, Ashleigh S, Yu, Jingxian, Hayes, Andrew, Feng, Jiage, Marshall, Andrew C, Noll, Benjamin, Milne, Robert, Cini, Danielle, Wilce, Matthew CJ, Booker, Grant W, Bruning, John B, Polyak, Steven W, Abell, Andrew D
المصدر: ACS Chemical Biology. 14:1990-1997
مصطلحات موضوعية: pharmacokinetic profile, 0301 basic medicine, Staphylococcus aureus, medicine.drug_class, Antibiotics, Microbial Sensitivity Tests, Molecular Dynamics Simulation, Crystallography, X-Ray, medicine.disease_cause, 01 natural sciences, Biochemistry, metabolic stability, Microbiology, Mice, 03 medical and health sciences, chemistry.chemical_compound, Bacterial Proteins, Drug Stability, Biotin, medicine, Animals, Carbon-Nitrogen Ligases, Enzyme Inhibitors, chemistry.chemical_classification, Sulfonamides, DNA ligase, 010405 organic chemistry, molecular dynamics simulations, General Medicine, Phosphate, Anti-Bacterial Agents, Rats, 0104 chemical sciences, Sulfonamide, 030104 developmental biology, chemistry, Drug Design, Molecular Medicine
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4
المؤلفون: Nicholas C, Schumann, Kwang Jun, Lee, Andrew P, Thompson, Wanisa, Salaemae, Jordan L, Pederick, Thomas, Avery, Birgit I, Gaiser, James, Hodgkinson-Bean, Grant W, Booker, Steven W, Polyak, John B, Bruning, Kate L, Wegener, Andrew D, Abell
المصدر: ACS chemical biology. 16(11)
مصطلحات موضوعية: Drug Development, Molecular Structure, Antitubercular Agents, Carbon-Nitrogen Ligases, Mycobacterium tuberculosis, Enzyme Inhibitors, Crystallography, X-Ray, Protein Binding
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5
المؤلفون: Tara L. Pukala, Andrew J. Hayes, Louise M. Sternicki, Keith E. Shearwin, Jiulia Satiaputra, Steven W. Polyak, Grant W. Booker
المساهمون: Satiaputra, Jiulia, Sternicki, Louise M, Hayes, Andrew J, Pukala, Tara L, Booker, Grant W, Shearwin, Keith E, Polyak, Steven W
المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reportsمصطلحات موضوعية: 0301 basic medicine, Spectrometry, Mass, Electrospray Ionization, Staphylococcus aureus, Repressor, Biotin, lcsh:Medicine, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Bacterial Proteins, biotin, Nanotechnology, Carbon-Nitrogen Ligases, Amino Acid Sequence, lcsh:Science, chemistry.chemical_classification, DNA ligase, Multidisciplinary, biology, Escherichia coli Proteins, lcsh:R, DNA, Protein Structure, Tertiary, Repressor Proteins, Biotin transport, 030104 developmental biology, Biochemistry, chemistry, Biotinylation, biology.protein, Fatty acid elongation, lcsh:Q, Protein A, Dimerization, 030217 neurology & neurosurgery, Protein Binding
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6
المساهمون: Thompson, Andrew P, Wegener, Kate L, Booker, Grant W, Polyak, Steven W, Bruning, John B
المصدر: Acta Crystallographica Section D Structural Biology. 74:965-972
مصطلحات موضوعية: 0301 basic medicine, Biochemistry & Molecular Biology, Cytidine triphosphate, Protein Conformation, Cytidine Triphosphate, Biophysics, Plasma protein binding, ligand, Crystallography, X-Ray, Ligands, Binding, Competitive, Biochemical Research Methods, Mycobacterium tuberculosis, 03 medical and health sciences, chemistry.chemical_compound, Protein structure, Structural Biology, Transferase, Carbon-Nitrogen Ligases, Binding site, Crystallography, Binding Sites, 030102 biochemistry & molecular biology, biology, Chemistry, exchange, biology.organism_classification, Combinatorial chemistry, Adenosine Diphosphate, Adenosine diphosphate, 030104 developmental biology, dethiobiotin synthetase, ADP binding, Protein Binding
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7دورية أكاديمية
المصدر: Antibiotics, Vol 5, Iss 3, p 26 (2016)
مصطلحات موضوعية: antibiotic, biotin, biotin protein ligase, Staphylococcus aureus, inhibitor design, X-ray crystallography, in situ click chemistry, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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8
المؤلفون: Stephanie Nguyen, Nicole R. Pendini, Louise M. Sternicki, Grant W. Booker, Yoann Huet, Kate L. Wegener, Perdita E. Barran, Kamila J. Pacholarz, Tara L. Pukala, Steven W. Polyak, Rachel Baltz
المساهمون: Sternicki, Louise M, Nguyen, Stephanie, Pacholarz, Kamila J, Barran, Perdita, Pendini, Nicole R, Booker, Grant W, Huet, Yoanne, Baltz, Rachel, Wegener, Kate L, Pukala, Tara L, Polyak, Steven W
المصدر: Archives of biochemistry and biophysics. 691
مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, Saccharomyces cerevisiae, Biophysics, Biochemistry, Substrate Specificity, Fungal Proteins, 03 medical and health sciences, chemistry.chemical_compound, zymoseptoria tritici, Biotin, Ascomycota, biotin, saccharomyces cerevisiae, Carbon-Nitrogen Ligases, biotin protein ligase, Enzyme Inhibitors, Molecular Biology, Botrytis cinerea, Protein Unfolding, chemistry.chemical_classification, DNA ligase, 030102 biochemistry & molecular biology, biology, Protein Stability, biology.organism_classification, Yeast, 030104 developmental biology, Enzyme, chemistry, Biotinylation, fungal pathogens, Botrytis, botrytis cinerea, Bacteria
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9دورية أكاديمية
المؤلفون: Christine Böttcher, Eric G Dennis, Grant W Booker, Steven W Polyak, Paul K Boss, Christopher Davies
المصدر: PLoS ONE, Vol 7, Iss 5, p e37632 (2012)
وصف الملف: electronic resource
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10
المؤلفون: Wanida Phetsang, Mark A. T. Blaskovich, Zikai Feng, Ashleigh S. Paparella, Jiage Feng, Mark E. Cooper, Andrew D. Abell, Beatriz Blanco-Rodriguez, Grant W. Booker, Steven W. Polyak
المساهمون: Paparella, Ashleigh S, Feng, Jiage, Blanco-Rodriguez, Beatriz, Feng, Zikai, Phetsang, Wanida, Blaskovich, Mark AT, Cooper, Matthew A, Booker, Grant W, Polyak, Steven W, Abell, Andrew D
المصدر: Tetrahedron. 74:1175-1183
مصطلحات موضوعية: staphylococcus aureus, 0301 basic medicine, enzyme inhibitors, Mutant, medicine.disease_cause, 01 natural sciences, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Biotin, antibiotic, Drug Discovery, medicine, Fluorescence microscope, biotin protein ligase, Escherichia coli, chemistry.chemical_classification, DNA ligase, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, biology.organism_classification, Molecular biology, 0104 chemical sciences, 030104 developmental biology, Staphylococcus aureus, azide-alkyne cycloaddition, Efflux, Bacteria
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