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1دورية أكاديمية
المؤلفون: Jiang X; VA Palo Alto Health Care System, Palo Alto, California, USA.; Stanford University School of Medicine, Stanford, California, USA., Tian W; VA Palo Alto Health Care System, Palo Alto, California, USA.; Stanford University School of Medicine, Stanford, California, USA., Granucci EJ; VA Palo Alto Health Care System, Palo Alto, California, USA.; Stanford University School of Medicine, Stanford, California, USA., Tu AB; VA Palo Alto Health Care System, Palo Alto, California, USA.; Stanford University School of Medicine, Stanford, California, USA., Kim D; VA Palo Alto Health Care System, Palo Alto, California, USA.; Stanford University School of Medicine, Stanford, California, USA., Dahms P; VA Palo Alto Health Care System, Palo Alto, California, USA.; Stanford University School of Medicine, Stanford, California, USA., Pasupneti S; VA Palo Alto Health Care System, Palo Alto, California, USA.; Stanford University School of Medicine, Stanford, California, USA., Peng G; VA Palo Alto Health Care System, Palo Alto, California, USA.; Stanford University School of Medicine, Stanford, California, USA., Kim Y; VA Palo Alto Health Care System, Palo Alto, California, USA.; Stanford University School of Medicine, Stanford, California, USA., Lim AH; VA Palo Alto Health Care System, Palo Alto, California, USA.; Stanford University School of Medicine, Stanford, California, USA., Espinoza FH; Stanford University School of Medicine, Stanford, California, USA., Cribb M; Georgia Institute of Technology, Atlanta, Georgia, USA., Dixon JB; Georgia Institute of Technology, Atlanta, Georgia, USA., Rockson SG; Stanford University School of Medicine, Stanford, California, USA., Semenza GL; Vascular Biology, Institute for Cell Engineering.; Department of Pediatrics.; Department of Medicine.; Department of Oncology.; Department of Radiation Oncology, and.; Department of Biological Chemistry, and.; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Nicolls MR; VA Palo Alto Health Care System, Palo Alto, California, USA.; Stanford University School of Medicine, Stanford, California, USA.
المصدر: The Journal of clinical investigation [J Clin Invest] 2020 Oct 01; Vol. 130 (10), pp. 5562-5575.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
مواضيع طبية MeSH: Basic Helix-Loop-Helix Transcription Factors/*deficiency , Lymphatic System/*metabolism , Lymphatic System/*pathology , Lymphedema/*metabolism , Lymphedema/*pathology, Angiopoietin-1/genetics ; Angiopoietin-1/therapeutic use ; Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Disease Models, Animal ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Female ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Lymphatic System/embryology ; Lymphedema/etiology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Phosphorylation ; Pregnancy ; Receptor, TIE-2/metabolism ; Signal Transduction
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2دورية أكاديمية
المؤلفون: Petrozziello T; Sean M. Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts., Mills AN; Sean M. Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts., Farhan SMK; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Mueller KA; Sean M. Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts., Granucci EJ; Sean M. Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts., Glajch KE; Sean M. Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts., Chan J; Biostatistics Center, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts., Chew S; Sean M. Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts., Berry JD; Sean M. Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts., Sadri-Vakili G; Sean M. Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts.
المصدر: Muscle & nerve [Muscle Nerve] 2020 Aug; Vol. 62 (2), pp. 272-283. Date of Electronic Publication: 2020 May 29.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 7803146 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4598 (Electronic) Linking ISSN: 0148639X NLM ISO Abbreviation: Muscle Nerve Subsets: MEDLINE
مواضيع طبية MeSH: Amyotrophic Lateral Sclerosis/*genetics , Inflammation/*metabolism , Lipocalin-2/*genetics , Motor Cortex/*metabolism , Spinal Cord/*metabolism, Adult ; Aged ; Aged, 80 and over ; Amyotrophic Lateral Sclerosis/metabolism ; Amyotrophic Lateral Sclerosis/physiopathology ; Blotting, Western ; Case-Control Studies ; Cell Death ; Cell Line, Tumor ; Cytokines/drug effects ; Cytokines/metabolism ; Enzyme-Linked Immunosorbent Assay ; Female ; Fluorescent Antibody Technique ; Humans ; In Vitro Techniques ; Lipocalin-2/antagonists & inhibitors ; Lipocalin-2/metabolism ; Lipocalin-2/pharmacology ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Real-Time Polymerase Chain Reaction
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3دورية أكاديمية
المؤلفون: Granucci EJ; Healey Center for ALS at MassGeneral Hospital, Massachusetts General Hospital, Boston, MA, USA., Griciuc A; Genetics and Aging Research Unit, McCance Center for Brain Health, MassGeneral Institute for Neurodegenerative disease, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, 02129, USA., Mueller KA; Healey Center for ALS at MassGeneral Hospital, Massachusetts General Hospital, Boston, MA, USA., Mills AN; Healey Center for ALS at MassGeneral Hospital, Massachusetts General Hospital, Boston, MA, USA., Le H; Genetics and Aging Research Unit, McCance Center for Brain Health, MassGeneral Institute for Neurodegenerative disease, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, 02129, USA., Dios AM; Healey Center for ALS at MassGeneral Hospital, Massachusetts General Hospital, Boston, MA, USA., McGinty D; Genetics and Aging Research Unit, McCance Center for Brain Health, MassGeneral Institute for Neurodegenerative disease, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, 02129, USA., Pereira J; Healey Center for ALS at MassGeneral Hospital, Massachusetts General Hospital, Boston, MA, USA., Elmaleh D; AZTherapies, Boston, MA, USA., Berry JD; Healey Center for ALS at MassGeneral Hospital, Massachusetts General Hospital, Boston, MA, USA., Paganoni S; Healey Center for ALS at MassGeneral Hospital, Massachusetts General Hospital, Boston, MA, USA.; Spaulding Rehabilitation Hospital, Department of PM&R, Harvard Medical School, Boston, MA, USA., Cudkowicz ME; Healey Center for ALS at MassGeneral Hospital, Massachusetts General Hospital, Boston, MA, USA., Tanzi RE; Genetics and Aging Research Unit, McCance Center for Brain Health, MassGeneral Institute for Neurodegenerative disease, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, 02129, USA., Sadri-Vakili G; Healey Center for ALS at MassGeneral Hospital, Massachusetts General Hospital, Boston, MA, USA. gsadrivakili@mgh.harvard.edu.
المصدر: Scientific reports [Sci Rep] 2019 Nov 27; Vol. 9 (1), pp. 17728. Date of Electronic Publication: 2019 Nov 27.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
مواضيع طبية MeSH: Amyotrophic Lateral Sclerosis/*drug therapy , Anti-Inflammatory Agents/*therapeutic use , Cromolyn Sodium/*therapeutic use , Neuroprotective Agents/*therapeutic use, Amyotrophic Lateral Sclerosis/genetics ; Animals ; Anti-Inflammatory Agents/pharmacology ; Cromolyn Sodium/pharmacology ; Cytokines/blood ; Cytokines/genetics ; Cytokines/metabolism ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Motor Neurons/drug effects ; Neuromuscular Junction/drug effects ; Neuroprotective Agents/pharmacology ; Spinal Cord/drug effects ; Spinal Cord/metabolism ; Superoxide Dismutase-1/genetics
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4دورية أكاديمية
المؤلفون: Dios AM; Sean M Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts, USA., Babu S; Sean M Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts, USA., Granucci EJ; Sean M Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts, USA., Mueller KA; Sean M Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts, USA., Mills AN; Sean M Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts, USA., Alshikho MJ; Sean M Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts, USA.; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA., Zürcher NR; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA., Cernasov P; Sean M Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts, USA., Gilbert TM; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA., Glass JD; Department of Neurology, Emory University, Atlanta, Georgia, USA., Berry JD; Sean M Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts, USA., Atassi N; Sean M Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts, USA.; Sanofi-Genzyme, Cambridge, Massachusetts, USA., Hooker JM; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA., Sadri-Vakili G; Sean M Healey & AMG Center for ALS at Mass General, Massachusetts General Hospital, Boston, Massachusetts, USA.
المصدر: Muscle & nerve [Muscle Nerve] 2019 Oct; Vol. 60 (4), pp. 443-452. Date of Electronic Publication: 2019 Jul 16.
نوع المنشور: Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 7803146 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4598 (Electronic) Linking ISSN: 0148639X NLM ISO Abbreviation: Muscle Nerve Subsets: MEDLINE
مواضيع طبية MeSH: Amyotrophic Lateral Sclerosis/*genetics , Histone Deacetylases/*genetics , Motor Cortex/*metabolism , Spinal Cord/*metabolism, Adamantane/analogs & derivatives ; Adult ; Aged ; Aged, 80 and over ; Amyotrophic Lateral Sclerosis/diagnostic imaging ; Amyotrophic Lateral Sclerosis/metabolism ; Amyotrophic Lateral Sclerosis/pathology ; Brain/diagnostic imaging ; Brain/metabolism ; Carbon Radioisotopes ; Case-Control Studies ; Cerebral Cortex/diagnostic imaging ; Cerebral Cortex/metabolism ; Cerebral Cortex/pathology ; Cross-Sectional Studies ; Female ; Histone Deacetylases/metabolism ; Histones/metabolism ; Humans ; Hydroxamic Acids ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Molecular Imaging ; Motor Cortex/diagnostic imaging ; Motor Cortex/pathology ; Multimodal Imaging ; Positron-Emission Tomography ; RNA, Messenger/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Spinal Cord/diagnostic imaging ; Spinal Cord/pathology
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5دورية أكاديمية
المؤلفون: Mueller KA; NeuroEpigenetics Laboratory, MassGeneral Institute for Neurodegenerative Disease (MIND), Massachusetts General Hospital, Boston, MA, 02129-4404, USA., Glajch KE; NeuroEpigenetics Laboratory, MassGeneral Institute for Neurodegenerative Disease (MIND), Massachusetts General Hospital, Boston, MA, 02129-4404, USA., Huizenga MN; NeuroEpigenetics Laboratory, MassGeneral Institute for Neurodegenerative Disease (MIND), Massachusetts General Hospital, Boston, MA, 02129-4404, USA., Wilson RA; NeuroEpigenetics Laboratory, MassGeneral Institute for Neurodegenerative Disease (MIND), Massachusetts General Hospital, Boston, MA, 02129-4404, USA., Granucci EJ; NeuroEpigenetics Laboratory, MassGeneral Institute for Neurodegenerative Disease (MIND), Massachusetts General Hospital, Boston, MA, 02129-4404, USA., Dios AM; NeuroEpigenetics Laboratory, MassGeneral Institute for Neurodegenerative Disease (MIND), Massachusetts General Hospital, Boston, MA, 02129-4404, USA., Tousley AR; Cellular Neurobiology Laboratory, MassGeneral Institute for Neurodegenerative Disease (MIND), Massachusetts General Hospital, Boston, MA, 02129-4404, USA., Iuliano M; Cellular Neurobiology Laboratory, MassGeneral Institute for Neurodegenerative Disease (MIND), Massachusetts General Hospital, Boston, MA, 02129-4404, USA., Weisman E; Cellular Neurobiology Laboratory, MassGeneral Institute for Neurodegenerative Disease (MIND), Massachusetts General Hospital, Boston, MA, 02129-4404, USA., LaQuaglia MJ; Department of Surgery, Boston Children's Hospital, Boston, USA., DiFiglia M; Cellular Neurobiology Laboratory, MassGeneral Institute for Neurodegenerative Disease (MIND), Massachusetts General Hospital, Boston, MA, 02129-4404, USA., Kegel-Gleason K; Cellular Neurobiology Laboratory, MassGeneral Institute for Neurodegenerative Disease (MIND), Massachusetts General Hospital, Boston, MA, 02129-4404, USA., Vakili K; Department of Surgery, Boston Children's Hospital, Boston, USA., Sadri-Vakili G; NeuroEpigenetics Laboratory, MassGeneral Institute for Neurodegenerative Disease (MIND), Massachusetts General Hospital, Boston, MA, 02129-4404, USA. gsadrivakili@mgh.harvard.edu.
المصدر: Scientific reports [Sci Rep] 2018 Jul 27; Vol. 8 (1), pp. 11355. Date of Electronic Publication: 2018 Jul 27.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
مواضيع طبية MeSH: Signal Transduction*, Brain/*pathology , Huntington Disease/*metabolism , Huntington Disease/*pathology , Neural Stem Cells/*metabolism , Protein Serine-Threonine Kinases/*metabolism, 14-3-3 Proteins/metabolism ; Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Disease Models, Animal ; Hippo Signaling Pathway ; Humans ; Neural Stem Cells/pathology ; Phosphoproteins/genetics ; Phosphoproteins/metabolism ; Phosphorylation ; Protein Binding ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Transcription Factors ; Transcription, Genetic ; YAP-Signaling Proteins