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المؤلفون: Boruah N; Department of Medicine, Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Hoyos D; Computational Oncology, Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY., Moses R; Department of Medicine, Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Hausler R; Department of Medicine, Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Desai H; Department of Medicine, Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Le AN; Department of Medicine, Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Good M; Department of Medicine, Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Kelly G; Department of Medicine, Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Raghavakaimal A; Department of Medicine, Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Tayeb M; Department of Medicine, Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Narasimhamurthy M; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia PA., Doucette A; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Gabriel P; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Feldman MJ; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia PA., Park J; Departments of Medicine and Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY., de Rodas ML; Department of Pathology, Yale School of Medicine, New Haven, CT., Schalper KA; Department of Pathology, Yale School of Medicine, New Haven, CT., Goldfarb SB; Departments of Medicine and Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical Center, New York, NY., Nayak A; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia PA., Levine AJ; Institute for Advanced Study, Princeton, NJ., Greenbaum BD; Computational Oncology, Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Physiology, Biophysics & Systems Biology, Weill Cornell Medical Center, New York, NY., Maxwell KN; Department of Medicine, Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.; Corporal Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Apr 05. Date of Electronic Publication: 2024 Apr 05.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Memon D; European Molecular Biology Laboratory (EMBL), European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, UK; M:M Bio Limited, 99 Park Drive, Milton, Abingdon, UK., Schoenfeld AJ; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Ye D; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Mark Foundation Center for Immunotherapy, Immune Signaling, and Radiation, University of Pennsylvania, Philadelphia, PA, USA., Fromm G; Shattuck Labs, Durham, NC, USA., Rizvi H; Druckenmiller Center for Lung Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Early Clinical Development, Oncology R&D, AstraZeneca, New York, NY, USA., Zhang X; Data Sciences and Quantitative Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Keddar MR; Oncology Data Science, Oncology R&D, AstraZeneca, Cambridge, UK., Mathew D; Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Institute for Immunology and Immune Health, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA., Yoo KJ; Shattuck Labs, Durham, NC, USA., Qiu J; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Mark Foundation Center for Immunotherapy, Immune Signaling, and Radiation, University of Pennsylvania, Philadelphia, PA, USA., Lihm J; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Miriyala J; Shattuck Labs, Durham, NC, USA., Sauter JL; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Luo J; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chow A; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Bhanot UK; Precision Pathology Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA., McCarthy C; Druckenmiller Center for Lung Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Vanderbilt CM; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Liu C; Ludwig Collaborative and Swim Across America Laboratory, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA., Abu-Akeel M; Ludwig Collaborative and Swim Across America Laboratory, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA., Plodkowski AJ; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., McGranahan N; Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK., Łuksza M; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Greenbaum BD; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Merghoub T; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medicine, New York, NY, USA; Ludwig Collaborative and Swim Across America Laboratory, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA; Parker Institute for Cancer Immunotherapy, MSK, New York, NY, USA; Human Oncology and Pathogenesis Program, MSK, New York, NY, USA., Achour I; Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK., Barrett JC; Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK., Stewart R; Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK., Beltrao P; European Molecular Biology Laboratory (EMBL), European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK; Institute of Molecular Systems Biology, ETH Zürich, Zurich, Switzerland., Schreiber TH; Shattuck Labs, Durham, NC, USA., Minn AJ; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Mark Foundation Center for Immunotherapy, Immune Signaling, and Radiation, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: andyminn@upenn.edu., Miller ML; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, UK; Oncology Data Science, Oncology R&D, AstraZeneca, Cambridge, UK. Electronic address: martin.miller.publications@gmail.com., Hellmann MD; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medicine, New York, NY, USA; Early Clinical Development, Oncology R&D, AstraZeneca, New York, NY, USA; Parker Institute for Cancer Immunotherapy, MSK, New York, NY, USA. Electronic address: hellmanm@mskcc.org.

المصدر: Cancer cell [Cancer Cell] 2024 Feb 12; Vol. 42 (2), pp. 209-224.e9. Date of Electronic Publication: 2024 Jan 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/genetics , Lung Neoplasms*/drug therapy , Lung Neoplasms*/genetics, Humans ; Animals ; Mice ; Signal Transduction ; Immunotherapy ; Antigen Presentation ; B7-H1 Antigen/metabolism ; Tumor Microenvironment

المؤلفون: Baldwin ET; ROME Therapeutics, Boston, MA, USA., van Eeuwen T; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY, USA., Hoyos D; Computational Oncology, Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Zalevsky A; Department of Bioengineering and Therapeutic Sciences University of California, San Francisco, San Francisco, CA, USA.; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA, USA.; Quantitative Biology Institute, University of California, San Francisco, San Francisco, CA, USA., Tchesnokov EP; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada., Sánchez R; ROME Therapeutics, Boston, MA, USA., Miller BD; Department of Pathology, Dana Farber Cancer Institute and Harvard Medical School, Boston, MA, USA., Di Stefano LH; European Research Institute for the Biology of Ageing, University Medical Center Groningen, Groningen, The Netherlands., Ruiz FX; Center for Advanced Biotechnology and Medicine and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, USA., Hancock M; Department of Bioengineering and Therapeutic Sciences University of California, San Francisco, San Francisco, CA, USA.; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA, USA.; Quantitative Biology Institute, University of California, San Francisco, San Francisco, CA, USA., Işik E; Department of Pathology, Dana Farber Cancer Institute and Harvard Medical School, Boston, MA, USA., Mendez-Dorantes C; Department of Pathology, Dana Farber Cancer Institute and Harvard Medical School, Boston, MA, USA., Walpole T; Charles River Laboratories, Chesterford Research Park, Saffron Walden, UK., Nichols C; Charles River Laboratories, Chesterford Research Park, Saffron Walden, UK., Wan P; Charles River Laboratories, Chesterford Research Park, Saffron Walden, UK., Riento K; Charles River Laboratories, Chesterford Research Park, Saffron Walden, UK., Halls-Kass R; Charles River Laboratories, Chesterford Research Park, Saffron Walden, UK., Augustin M; Proteros Biostructures GmbH, Martinsried, Planegg, Germany., Lammens A; Proteros Biostructures GmbH, Martinsried, Planegg, Germany., Jestel A; Proteros Biostructures GmbH, Martinsried, Planegg, Germany., Upla P; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY, USA., Xibinaku K; Whitehead Institute for Biomedical Research, Cambridge, MA, USA., Congreve S; Whitehead Institute for Biomedical Research, Cambridge, MA, USA., Hennink M; Whitehead Institute for Biomedical Research, Cambridge, MA, USA., Rogala KB; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA., Schneider AM; Structural Biology of Selfish RNA, Department of Protein Evolution, Max Planck Institute for Biology, Tübingen, Germany., Fairman JE; Johns Hopkins University School of Medicine, Baltimore, MD, USA., Christensen SM; Department of Biology, University of Texas at Arlington, Arlington, TX, USA., Desrosiers B; ROME Therapeutics, Boston, MA, USA., Bisacchi GS; ROME Therapeutics, Boston, MA, USA., Saunders OL; ROME Therapeutics, Boston, MA, USA., Hafeez N; ROME Therapeutics, Boston, MA, USA., Miao W; ROME Therapeutics, Boston, MA, USA., Kapeller R; ROME Therapeutics, Boston, MA, USA., Zaller DM; ROME Therapeutics, Boston, MA, USA., Sali A; Department of Bioengineering and Therapeutic Sciences University of California, San Francisco, San Francisco, CA, USA.; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA, USA.; Quantitative Biology Institute, University of California, San Francisco, San Francisco, CA, USA., Weichenrieder O; Structural Biology of Selfish RNA, Department of Protein Evolution, Max Planck Institute for Biology, Tübingen, Germany., Burns KH; Department of Pathology, Dana Farber Cancer Institute and Harvard Medical School, Boston, MA, USA. kathleenh_burns@dfci.harvard.edu., Götte M; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada. gotte@ualberta.ca., Rout MP; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY, USA. rout@rockefeller.edu., Arnold E; Center for Advanced Biotechnology and Medicine and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, USA. arnold@cabm.rutgers.edu., Greenbaum BD; Computational Oncology, Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. greenbab@mskcc.org.; Physiology, Biophysics & Systems Biology, Weill Cornell Medicine, Weill Cornell Medical College, New York, NY, USA. greenbab@mskcc.org., Romero DL; ROME Therapeutics, Boston, MA, USA. dlromero@rometx.com., LaCava J; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY, USA. j.p.lacava@rug.nl.; European Research Institute for the Biology of Ageing, University Medical Center Groningen, Groningen, The Netherlands. j.p.lacava@rug.nl., Taylor MS; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. mstaylor@mgh.harvard.edu.

المصدر: Nature [Nature] 2024 Feb; Vol. 626 (7997), pp. 194-206. Date of Electronic Publication: 2023 Dec 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Endonucleases*/chemistry , Endonucleases*/genetics , Endonucleases*/metabolism , Long Interspersed Nucleotide Elements*/genetics , RNA-Directed DNA Polymerase*/chemistry , RNA-Directed DNA Polymerase*/genetics , RNA-Directed DNA Polymerase*/metabolism , Reverse Transcription*, Humans ; Cryoelectron Microscopy ; RNA/genetics ; Crystallography, X-Ray ; DNA/biosynthesis ; DNA/genetics ; Immunity, Innate ; Interferons/biosynthesis

المؤلفون: Yao N; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Greenbaum BD; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, Weill Cornell Medical College, New York, NY, USA. Electronic address: greenbab@mskcc.org.

المصدر: Immunity [Immunity] 2023 Nov 14; Vol. 56 (11), pp. 2466-2468.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE

مواضيع طبية MeSH: Antigens, Neoplasm* , Neoplasms*, Humans ; Machine Learning ; Immunotherapy

المؤلفون: DeWolf S; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Elhanati Y; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Nichols K; Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Waters NR; Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Nguyen CL; Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Slingerland JB; Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Rodriguez N; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lyudovyk O; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Giardina PA; Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kousa AI; Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Andrlová H; Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ceglia N; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Fei T; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kappagantula R; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Li Y; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Aleynick N; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Baez P; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Murali R; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Hayashi A; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Pathology, Kyorin University, Mitaka City, Tokyo, Japan., Lee N; Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gipson B; Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Rangesa M; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Katsamakis Z; Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Dai A; Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Blouin AG; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Arcila M; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Masilionis I; Program for Computational and System Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chaligne R; Program for Computational and System Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ponce DM; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medical College, New York, NY, USA., Landau HJ; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medical College, New York, NY, USA., Politikos I; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medical College, New York, NY, USA., Tamari R; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medical College, New York, NY, USA., Hanash AM; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medical College, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Jenq RR; Departments of Genomic Medicine and Stem Cell Transplantation Cellular Therapy, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Giralt SA; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medical College, New York, NY, USA., Markey KA; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Division of Medical Oncology, University of Washington, Seattle, WA, USA., Zhang Y; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Perales MA; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medical College, New York, NY, USA., Socci ND; Bioinformatics Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Greenbaum BD; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Physiology, Biophysics, and Systems Biology, Weill Cornell Medicine, Weill Cornell Medical College, New York, NY, USA., Iacobuzio-Donahue CA; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Hollmann TJ; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Bristol Myers Squibb, Lawrenceville, NJ 08540, USA., van den Brink MRM; Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medical College, New York, NY, USA., Peled JU; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medical College, New York, NY, USA.

المصدر: Science translational medicine [Sci Transl Med] 2023 Jul 26; Vol. 15 (706), pp. eabq0476. Date of Electronic Publication: 2023 Jul 26.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Hematopoietic Stem Cell Transplantation* , Graft vs Host Disease*/pathology, Humans ; Mice ; Animals ; T-Lymphocytes/pathology ; Receptors, Antigen, T-Cell

المؤلفون: Ceglia N; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. ceglian@mskcc.org., Sethna Z; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Immuno-Oncology Service, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Freeman SS; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Uhlitz F; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Bojilova V; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Rusk N; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Burman B; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chow A; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Salehi S; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kabeer F; Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Aparicio S; Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Greenbaum BD; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Physiology, Biophysics & Systems Biology, Weill Cornell Medicine, Weill Cornell Medical College, New York, NY, USA., Shah SP; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., McPherson A; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

المصدر: Nature communications [Nat Commun] 2023 Jul 20; Vol. 14 (1), pp. 4400. Date of Electronic Publication: 2023 Jul 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Single-Cell Analysis*/methods , Gene Expression Profiling*, Principal Component Analysis ; Exome Sequencing ; Sequence Analysis, RNA/methods ; Cluster Analysis

المؤلفون: Rojas LA; Immuno-Oncology Service, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Sethna Z; Immuno-Oncology Service, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Soares KC; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Olcese C; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Pang N; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Patterson E; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lihm J; Computational Oncology Service, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ceglia N; Computational Oncology Service, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Guasp P; Immuno-Oncology Service, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chu A; Computational Oncology Service, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Yu R; Immuno-Oncology Service, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chandra AK; Immuno-Oncology Service, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Waters T; Immuno-Oncology Service, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ruan J; Immuno-Oncology Service, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Amisaki M; Immuno-Oncology Service, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Zebboudj A; Immuno-Oncology Service, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Odgerel Z; Immuno-Oncology Service, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Payne G; Immuno-Oncology Service, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Derhovanessian E; BioNTech, Mainz, Germany., Müller F; BioNTech, Mainz, Germany., Rhee I; Genentech, San Francisco, CA, USA., Yadav M; Genentech, San Francisco, CA, USA., Dobrin A; Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Sadelain M; Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Łuksza M; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Cohen N; Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Tang L; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Basturk O; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gönen M; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Katz S; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Do RK; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Epstein AS; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Momtaz P; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Park W; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Sugarman R; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Varghese AM; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Won E; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Desai A; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Wei AC; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA., D'Angelica MI; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; David M. 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Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA. balachav@mskcc.org.

المصدر: Nature [Nature] 2023 Jun; Vol. 618 (7963), pp. 144-150. Date of Electronic Publication: 2023 May 10.

نوع المنشور: Clinical Trial, Phase I; Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Antigens, Neoplasm*/immunology , Cancer Vaccines*/immunology , Carcinoma, Pancreatic Ductal*/genetics , Carcinoma, Pancreatic Ductal*/immunology , Carcinoma, Pancreatic Ductal*/therapy , Lymphocyte Activation*/immunology , Pancreatic Neoplasms*/genetics , Pancreatic Neoplasms*/immunology , Pancreatic Neoplasms*/therapy , T-Lymphocytes*/cytology , T-Lymphocytes*/immunology, Humans ; Adjuvants, Immunologic/therapeutic use ; CD8-Positive T-Lymphocytes/cytology ; CD8-Positive T-Lymphocytes/immunology ; Immunotherapy ; mRNA Vaccines

المؤلفون: Sun S, Hong J, You E, Tsanov KM, Chacon-Barahona J, Gioacchino AD, Hoyos D, Li H, Jiang H, Ly H, Marhon S, Murali R, Chanda P, Karacay A, Vabret N, De Carvalho DD, LaCava J, Lowe SW, Ting DT, Iacobuzio-Donahue CA, Solovyov A, Greenbaum BD

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 May 20. Date of Electronic Publication: 2023 May 20.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE