المؤلفون: Boshuizen J; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Pencheva N; Genmab, Utrecht, the Netherlands., Krijgsman O; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Altimari DD; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Castro PG; Genmab, Utrecht, the Netherlands., de Bruijn B; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Ligtenberg MA; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Gresnigt-Van den Heuvel E; Genmab, Utrecht, the Netherlands., Vredevoogd DW; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Song JY; Division of Animal Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Visser N; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Apriamashvili G; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Janmaat ML; Genmab, Utrecht, the Netherlands., Plantinga TS; Genmab, Utrecht, the Netherlands., Franken P; Genmab, Utrecht, the Netherlands., Houtkamp M; Genmab, Utrecht, the Netherlands., Lingnau A; Genmab, Utrecht, the Netherlands., Jure-Kunkel M; Genmab, Princeton, New Jersey., Peeper DS; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands. d.peeper@nki.nl.

المصدر: Cancer research [Cancer Res] 2021 Apr 01; Vol. 81 (7), pp. 1775-1787. Date of Electronic Publication: 2021 Feb 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Immune Checkpoint Inhibitors/*therapeutic use , Immunoconjugates/*therapeutic use , Lung Neoplasms/*therapy , Melanoma/*therapy , Proto-Oncogene Proteins/*immunology , Receptor Protein-Tyrosine Kinases/*immunology, Animals ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cell Line, Tumor ; Combined Modality Therapy ; Drug Resistance, Neoplasm/immunology ; Drug Synergism ; HEK293 Cells ; Humans ; Immune Checkpoint Inhibitors/administration & dosage ; Immunoconjugates/administration & dosage ; Immunotherapy ; Lung Neoplasms/pathology ; Male ; Melanoma/pathology ; Mice ; Mice, Nude ; Mice, Transgenic ; Molecular Targeted Therapy/methods ; Proto-Oncogene Proteins/antagonists & inhibitors ; Receptor Protein-Tyrosine Kinases/antagonists & inhibitors ; Xenograft Model Antitumor Assays ; Axl Receptor Tyrosine Kinase

المؤلفون: Koopman LA; Genmab, Utrecht, Netherlands., Terp MG; Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Zom GG; Genmab, Utrecht, Netherlands., Janmaat ML; Genmab, Utrecht, Netherlands., Jacobsen K; Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Gresnigt-van den Heuvel E; Genmab, Utrecht, Netherlands., Brandhorst M; Genmab, Utrecht, Netherlands., Forssmann U; Genmab, Utrecht, Netherlands., de Bree F; Genmab, Utrecht, Netherlands., Pencheva N; Genmab, Utrecht, Netherlands., Lingnau A; Genmab, Utrecht, Netherlands., Zipeto MA; Crown Bioscience San Diego, San Diego, California, USA., Parren PW; Genmab, Utrecht, Netherlands.; Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, Netherlands., Breij EC; Genmab, Utrecht, Netherlands., Ditzel HJ; Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Department of Oncology, Odense University Hospital, Odense, Denmark.

المصدر: JCI insight [JCI Insight] 2019 Nov 01; Vol. 4 (21). Date of Electronic Publication: 2019 Nov 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*therapeutic use , Carcinoma, Non-Small-Cell Lung/*drug therapy , Immunoconjugates/*therapeutic use , Lung Neoplasms/*drug therapy , Proto-Oncogene Proteins/*immunology , Receptor Protein-Tyrosine Kinases/*immunology, Animals ; Humans ; Mice ; Xenograft Model Antitumor Assays ; Axl Receptor Tyrosine Kinase