لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

المؤلفون: Anand RP; eGenesis, Cambridge, MA, USA., Layer JV; eGenesis, Cambridge, MA, USA., Heja D; eGenesis, Cambridge, MA, USA., Hirose T; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Lassiter G; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Firl DJ; eGenesis, Cambridge, MA, USA.; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Paragas VB; eGenesis, Cambridge, MA, USA., Akkad A; eGenesis, Cambridge, MA, USA., Chhangawala S; eGenesis, Cambridge, MA, USA., Colvin RB; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Ernst RJ; eGenesis, Cambridge, MA, USA., Esch N; eGenesis, Cambridge, MA, USA., Getchell K; eGenesis, Cambridge, MA, USA., Griffin AK; eGenesis, Cambridge, MA, USA., Guo X; eGenesis, Cambridge, MA, USA., Hall KC; eGenesis, Cambridge, MA, USA., Hamilton P; eGenesis, Cambridge, MA, USA., Kalekar LA; eGenesis, Cambridge, MA, USA., Kan Y; eGenesis, Cambridge, MA, USA., Karadagi A; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Li F; eGenesis, Cambridge, MA, USA., Low SC; eGenesis, Cambridge, MA, USA., Matheson R; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Nehring C; eGenesis, Cambridge, MA, USA., Otsuka R; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Pandelakis M; eGenesis, Cambridge, MA, USA., Policastro RA; eGenesis, Cambridge, MA, USA., Pols R; eGenesis, Cambridge, MA, USA., Queiroz L; eGenesis, Cambridge, MA, USA., Rosales IA; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Serkin WT; eGenesis, Cambridge, MA, USA., Stiede K; eGenesis, Cambridge, MA, USA., Tomosugi T; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Xue Y; eGenesis, Cambridge, MA, USA., Zentner GE; eGenesis, Cambridge, MA, USA., Angeles-Albores D; eGenesis, Cambridge, MA, USA., Chris Chao J; eGenesis, Cambridge, MA, USA., Crabtree JN; eGenesis, Cambridge, MA, USA., Harken S; eGenesis, Cambridge, MA, USA., Hinkle N; eGenesis, Cambridge, MA, USA., Lemos T; eGenesis, Cambridge, MA, USA., Li M; eGenesis, Cambridge, MA, USA., Pantano L; eGenesis, Cambridge, MA, USA., Stevens D; eGenesis, Cambridge, MA, USA., Subedar OD; eGenesis, Cambridge, MA, USA., Tan X; eGenesis, Cambridge, MA, USA., Yin S; eGenesis, Cambridge, MA, USA., Anwar IJ; Duke Transplant Center, Department of Surgery, Duke University Medical Center, Durham, NC, USA., Aufhauser D; Department of Surgery, Division of Transplantation, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA., Capuano S; Wisconsin National Primate Research Center, Madison, WI, USA., Kaufman DB; Department of Surgery, Division of Transplantation, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA., Knechtle SJ; Duke Transplant Center, Department of Surgery, Duke University Medical Center, Durham, NC, USA., Kwun J; Duke Transplant Center, Department of Surgery, Duke University Medical Center, Durham, NC, USA., Shanmuganayagam D; Department of Animal and Dairy Science, University of Wisconsin, Madison, WI, USA., Markmann JF; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Church GM; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Wyss Institute of Biologically Inspired Engineering, Harvard University, Cambridge, MA, USA., Curtis M; eGenesis, Cambridge, MA, USA., Kawai T; Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Youd ME; eGenesis, Cambridge, MA, USA. michele.youd@egenesisbio.com., Qin W; eGenesis, Cambridge, MA, USA. wenning.qin@egenesisbio.com.

المصدر: Nature [Nature] 2023 Oct; Vol. 622 (7982), pp. 393-401. Date of Electronic Publication: 2023 Oct 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Graft Rejection*/immunology , Graft Rejection*/prevention & control , Kidney Transplantation*/methods , Macaca fascicularis* , Swine*/genetics , Transplantation, Heterologous*/methods, Animals ; Humans ; Animals, Genetically Modified ; Endothelial Cells/immunology ; Endothelial Cells/metabolism ; Polysaccharides/deficiency ; Transgenes/genetics