المؤلفون: Hansen MK, McVey MJ, White RF, Legos JJ, Brusq JM, Grillot DA, Issandou M, Barone FC

المصدر: Journal of Cardiovascular Pharmacology & Therapeutics; Jun2010, Vol. 15 Issue 2, p196-202, 7p

المؤلفون: Shearer BG; Research and Development, GlaxoSmithKline, Research Triangle Park, NC 27709, USA., Steger DJ, Way JM, Stanley TB, Lobe DC, Grillot DA, Iannone MA, Lazar MA, Willson TM, Billin AN

المصدر: Molecular endocrinology (Baltimore, Md.) [Mol Endocrinol] 2008 Feb; Vol. 22 (2), pp. 523-9. Date of Electronic Publication: 2007 Nov 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Endocrine Society Country of Publication: United States NLM ID: 8801431 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0888-8809 (Print) Linking ISSN: 08888809 NLM ISO Abbreviation: Mol Endocrinol Subsets: MEDLINE

مواضيع طبية MeSH: Ligands*, PPAR delta/*antagonists & inhibitors , PPAR-beta/*antagonists & inhibitors, Cells, Cultured ; Chromatin Immunoprecipitation ; Dose-Response Relationship, Drug ; Fatty Acids/metabolism ; Fluorescence Resonance Energy Transfer ; Gene Expression Regulation/drug effects ; Humans ; Molecular Structure ; Muscle, Skeletal/cytology ; Muscle, Skeletal/drug effects ; Muscle, Skeletal/metabolism ; Oxidation-Reduction/drug effects ; Sulfones/chemistry ; Sulfones/pharmacology ; Thiazoles/chemistry ; Thiazoles/pharmacology ; Thiophenes/chemistry ; Thiophenes/pharmacology

المؤلفون: Sierra ML; Department of Medicinal Chemistry, Laboratoire GlaxoSmithKline, Centre de Recherches, 25-27 avenue du Québec, 91951 Les Ulis, France, USA., Beneton V, Boullay AB, Boyer T, Brewster AG, Donche F, Forest MC, Fouchet MH, Gellibert FJ, Grillot DA, Lambert MH, Laroze A, Le Grumelec C, Linget JM, Montana VG, Nguyen VL, Nicodème E, Patel V, Penfornis A, Pineau O, Pohin D, Potvain F, Poulain G, Ruault CB, Saunders M, Toum J, Xu HE, Xu RX, Pianetti PM

المصدر: Journal of medicinal chemistry [J Med Chem] 2007 Feb 22; Vol. 50 (4), pp. 685-95. Date of Electronic Publication: 2007 Jan 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Cholesterol, HDL/*blood , PPAR alpha/*agonists , Propionates/*chemical synthesis , Thiazoles/*chemical synthesis, Animals ; Apolipoprotein A-I/genetics ; Cholesterol, VLDL/blood ; Crystallography, X-Ray ; Dogs ; Dyslipidemias/blood ; Dyslipidemias/drug therapy ; Humans ; Ligands ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Models, Molecular ; PPAR alpha/chemistry ; Propionates/pharmacokinetics ; Propionates/pharmacology ; Protein Structure, Tertiary ; Rats ; Rats, Wistar ; Structure-Activity Relationship ; Thiazoles/pharmacokinetics ; Thiazoles/pharmacology ; Triglycerides/blood

المؤلفون: Packham G; Ludwig Institute for Cancer Research, Imperial College School of Medicine at St. Mary's, London W2 1PG, UK., White EL, Eischen CM, Yang H, Parganas E, Ihle JN, Grillot DA, Zambetti GP, Nuñez G, Cleveland JL

المصدر: Genes & development [Genes Dev] 1998 Aug 15; Vol. 12 (16), pp. 2475-87.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 8711660 Publication Model: Print Cited Medium: Print ISSN: 0890-9369 (Print) Linking ISSN: 08909369 NLM ISO Abbreviation: Genes Dev Subsets: MEDLINE

مواضيع طبية MeSH: Proto-Oncogene Proteins*, Hematopoietic Cell Growth Factors/*physiology , Leukemia, Myeloid/*metabolism , Protein-Tyrosine Kinases/*metabolism , Proto-Oncogene Proteins c-bcl-2/*metabolism, Animals ; Apoptosis ; Base Sequence ; Cell Transformation, Neoplastic ; Gene Expression Regulation, Neoplastic ; Janus Kinase 2 ; Leukemia, Myeloid/genetics ; Leukemia, T-Cell/genetics ; Leukemia, T-Cell/metabolism ; Mice ; Molecular Sequence Data ; Mutagenesis, Insertional ; Proto-Oncogene Proteins c-bcl-2/genetics ; Retroviridae/genetics ; Sequence Alignment ; Tumor Cells, Cultured ; bcl-X Protein

المؤلفون: Solvason N; Department of Immunology, DNAX Research Institute, Palo Alto, California 94304, USA. nsolvason@anergen.com, Wu WW, Kabra N, Lund-Johansen F, Roncarolo MG, Behrens TW, Grillot DA, Nunez G, Lees E, Howard M

المصدر: The Journal of experimental medicine [J Exp Med] 1998 Apr 06; Vol. 187 (7), pp. 1081-91.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print Cited Medium: Print ISSN: 0022-1007 (Print) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE

مواضيع طبية MeSH: B-Lymphocytes/*metabolism , Gene Expression Regulation/*genetics , Immunoglobulins/*immunology , Mice, Transgenic/*immunology , Proto-Oncogene Proteins c-bcl-2/*genetics, Agammaglobulinaemia Tyrosine Kinase ; Animals ; Antigens, CD/immunology ; Apoptosis/physiology ; Bromodeoxyuridine/metabolism ; Cell Count ; Cell Cycle/physiology ; Cell Survival ; Disease Models, Animal ; Flow Cytometry ; Mice ; Mice, Inbred CBA ; Phenotype ; Protein Kinases/analysis ; Protein-Tyrosine Kinases/genetics ; Proto-Oncogene Proteins c-bcl-2/analysis ; Spleen/cytology ; bcl-X Protein

المؤلفون: Simonian PL; Department of Pathology and Comprehensive Cancer Center, The University of Michigan Medical School, Ann Arbor 48109, USA., Grillot DA, Nuñez G

المصدر: Oncogene [Oncogene] 1997 Oct 09; Vol. 15 (15), pp. 1871-5.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232 (Print) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Apoptosis/*drug effects , Membrane Proteins/*physiology , Proto-Oncogene Proteins c-bcl-2/*chemistry, Apoptosis/physiology ; Cell Line ; Dimerization ; Membrane Proteins/chemistry ; bcl-2 Homologous Antagonist-Killer Protein

المؤلفون: Simonian PL; Department of Pathology and Comprehensive Cancer Center, The University of Michigan Medical School, Ann Arbor 48109, USA., Grillot DA, Nuñez G

المصدر: Blood [Blood] 1997 Aug 01; Vol. 90 (3), pp. 1208-16.

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Print ISSN: 0006-4971 (Print) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Apoptosis/*genetics , Proto-Oncogene Proteins c-bcl-2/*physiology, Animals ; Apoptosis/drug effects ; Apoptosis/radiation effects ; Clone Cells/drug effects ; Clone Cells/radiation effects ; Drug Resistance, Neoplasm/genetics ; Etoposide/pharmacology ; Fluorouracil/pharmacology ; Gamma Rays ; Genes, bcl-2 ; Humans ; Hydroxyurea/pharmacology ; Methotrexate/pharmacology ; Mice ; Proto-Oncogene Proteins c-bcl-2/genetics ; Recombinant Fusion Proteins/physiology ; S Phase/drug effects ; Teniposide/pharmacology ; Transfection ; Vincristine/pharmacology ; bcl-X Protein

المؤلفون: Grillot DA; Department of Pathology, University of Michigan Medical School, Ann Arbor 48109, USA., González-García M, Ekhterae D, Duan L, Inohara N, Ohta S, Seldin MF, Nuñez G

المصدر: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 1997 May 15; Vol. 158 (10), pp. 4750-7.

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: American Association of Immunologists Country of Publication: United States NLM ID: 2985117R Publication Model: Print Cited Medium: Print ISSN: 0022-1767 (Print) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Proto-Oncogene Proteins c-bcl-2*, Proto-Oncogene Proteins/*genetics, Animals ; Base Sequence ; Chromosome Mapping ; Genes ; Humans ; Mice ; Molecular Sequence Data ; Promoter Regions, Genetic ; RNA, Messenger/genetics ; Sequence Alignment ; Sequence Homology, Nucleic Acid ; Transcription, Genetic ; bcl-X Protein

المؤلفون: Simonian PL; Department of Pathology and Comprehensive Cancer Center, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USA. Gabriel.Nunez@umich.edu, Grillot DA, Andrews DW, Leber B, Nuñez G

المصدر: The Journal of biological chemistry [J Biol Chem] 1996 Dec 13; Vol. 271 (50), pp. 32073-7.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis* , Proto-Oncogene Proteins c-bcl-2*, Proto-Oncogene Proteins/*metabolism, Animals ; Cell Line ; Cell Survival ; Cisplatin/pharmacology ; Electrophoresis, Polyacrylamide Gel ; Etoposide/pharmacology ; Fluorouracil/pharmacology ; Mutagenesis, Site-Directed ; Protein Conformation ; Proto-Oncogene Proteins/chemistry ; bcl-2-Associated X Protein

المؤلفون: Simonian PL; Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA., Grillot DA, Merino R, Nuñez G

المصدر: The Journal of biological chemistry [J Biol Chem] 1996 Sep 13; Vol. 271 (37), pp. 22764-72.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Proto-Oncogene Proteins c-bcl-2*, Antineoplastic Agents/*pharmacology , Apoptosis/*drug effects , Cisplatin/*pharmacology , Etoposide/*pharmacology , Proto-Oncogene Proteins/*antagonists & inhibitors , Proto-Oncogene Proteins/*pharmacology, Amino Acid Sequence ; Antineoplastic Agents, Phytogenic/pharmacology ; Conserved Sequence ; Dimerization ; Electrophoresis, Polyacrylamide Gel ; Molecular Sequence Data ; Protein Conformation ; bcl-2-Associated X Protein ; bcl-X Protein