المؤلفون: Menghao Huang, Kushan Chowdhury, Zhigang Fang, X. Charlie Dong, Ming O. Li, Suthat Liangpunsakul, Hyeong-Geug Kim

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 921-942 (2021)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: 0301 basic medicine, Sestrins, MPO, myeloperoxidase, Mitogen-Activated Protein Kinase Kinase 7, RC799-869, DMSO, dimethyl sulfoxide, FoxO, forkhead box O, Sesn1/2/3, sestrin1/2/3, medicine.disease_cause, TKO, triple knockout, Mice, PCR, polymerase chain reaction, 0302 clinical medicine, GSH, glutathione, Phosphorylation, NF-κB, nuclear factor kappa B, Original Research, Cat, catalase, Mice, Knockout, Sestrin, Gpx3, glutathione peroxidase 3, Il6, interleukin 6, WD, Western diet, biology, Chemistry, Kinase, Fatty liver, Tgfbr1, transforming growth factor beta receptor 1, Gastroenterology, Col1a1, collagen type 1 alpha 1, Nox1, NADPH oxidase 1, Diseases of the digestive system. Gastroenterology, Dgat2, diacylglycerol O-acyltransferase 2, Cell biology, Keap1, Kelch-like ECH-associated protein 1, C-Jun N-Terminal Kinase, Liver, Lipotoxicity, c-Jun N-terminal kinases, JNK, c-Jun N-terminal kinase, 030211 gastroenterology & hepatology, Disease Susceptibility, Signal transduction, NASH, nonalcoholic steatohepatitis, Gss, glutathione synthetase, Pdgfrb, platelet-derived growth factor receptor beta, Timp1, tissue inhibitor of metalloproteinase 1, Fasn, fatty acid synthase, Fatty Liver Disease, Sod, superoxide dismutase, Acta2, smooth muscle actin alpha 2, ER, endoplasmic reticulum, PA, palmitic acid, 03 medical and health sciences, 4-HNE, 4-hydroxynonenal, MKK, mitogen-activated protein kinase kinase, medicine, Animals, Humans, Srebp, sterol regulatory element-binding protein, Protein kinase A, KD, knockdown, MDA, malondialdehyde, Inflammation, KO, knockout, Hepatology, NRF2, nuclear factor erythroid 2-related like 2, JNK Mitogen-Activated Protein Kinases, Lipid Metabolism, medicine.disease, Tgfb1, transforming growth factor beta 1, WT, wild-type, mTORC, mechanistic target of rapamycin complex, Fatty Liver, AMPK, AMP-activated protein kinase, Disease Models, Animal, Oxidative Stress, Scd1, stearoyl-CoA desaturase 1, 030104 developmental biology, Gene Expression Regulation, Cytoprotection, Hepatocytes, biology.protein, BSA, bovine serum albumin, SD, standard deviation, DHE, dihydroethidium, PERK, protein kinase R-like endoplasmic reticulum kinase, Tnf, tumor necrosis factor, Biomarkers, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1574bc0f082fa7f7fd23bf88f6f9c6fc
http://www.sciencedirect.com/science/article/pii/S2352345X21000862

المؤلفون: James E. Goldman, Alice Tang, Michelle L. Olsen, Natasha L. Pacheco, Jiangtao Li, Daniel Flint, Brett S. Phinney, Anthony W. Herren, Fatima Khan, Michael R. Heaven

المصدر: Molecular & cellular proteomics : MCP, vol 21, iss 1
Molecular & Cellular Proteomics : MCP

مصطلحات موضوعية: Proteomics, Cnp, 2′,3′-cyclic-nucleotide 3′-phosphodiesterase, Nadk2, NAD kinase 2, mitochondrial, Pck2, phosphoenolpyruvate carboxykinase [GTP], mitochondrial, Slc16a1, monocarboxylate transporter 1, PPAR, peroxisome proliferator-activated receptor, Mog, myelin-oligodendrocyte glycoprotein, Nfe2l2, nuclear factor erythroid 2-related factor 2, Mlc1, membrane protein MLC1, Biochemistry, C1qc, complement C1q subcomponent subunit C, Transgenic, Analytical Chemistry, Acadl, Long-chain specific acyl-CoA dehydrogenase, mitochondrial, Myelin, Mice, Gsr, glutathione reductase, mitochondrial, Cryl1, lambda-crystallin homolog, Sqstm1, sequestosome-1, BCA, bicinchoninic acid assay, LC3, microtubule-associated protein 1A/1B-light chain 3, Gliosis, SRM, selected reaction monitoring, Aetiology, Gclm, glutamate--cysteine ligase regulatory subunit, μDIA, micro-data-independent acquisition, Acsl3, long-chain-fatty-acid--CoA ligase 3, Cat, catalase, Acot2, Acyl-coenzyme A thioesterase 2, Glial fibrillary acidic protein, Rps27a, ubiquitin-40S ribosomal protein S27a, Acsl6, long-chain-fatty-acid--CoA ligase 6, Aldh1l1, Cytosolic 10-formyltetrahydrofolate dehydrogenase, Slc25a18, mitochondrial glutamate carrier 2, Bsn, protein bassoon, Fabp7, fatty acid binding protein, brain, Plp1, myelin proteolipid protein, Gsta3, glutathione S-transferase A3, Prdx6, peroxiredoxin-6, Alexander Disease, Slc6a11, sodium- and chloride-dependent GABA transporter 3, Ccnd2, G1/S-specific cyclin-D2, Stxbp5l, syntaxin-binding protein 5-like, GAPDH, glyceraldehyde 3 phosphate dehydrogenase, Slc6a17, sodium-dependent neutral amino acid transporter SLC6A17, Biochemistry & Molecular Biology, Ilk, integrin-linked protein kinase, Kcnj10, ATP-sensitive inward rectifier potassium channel 10, Ugt8, Gan, gigaxonin, Ttyh1, protein tweety homolog 1, Hsp27, heat shock protein beta-1, TBI, traumatic brain injury, reactive gliosis, Hmgcs2, hydroxymethylglutaryl-CoA synthase, mitochondrial, Idh2, isocitrate dehydrogenase [NADP], mitochondrial, KEGG, Kyoto encyclopedia of genes and genomes, Genetics, Humans, Gpr37l1, prosaposin receptor GPR37L1, Molecular Biology, Txnrd1, thioredoxin reductase 1, cytoplasmic, Slc38a3, sodium-coupled neutral amino acid transporter 3, Animal, DAVID, database for annotation, visualization and integrated discovery, GFAP, glial fibrillary acidic protein, astrocytes, Rack1, receptor of activated protein C kinase 1, Ugt8, 2-hydroxyacylsphingosine 1-beta-galactosyltransferase, Apoa1, apolipoprotein A-I, medicine.disease, Oligodendrocyte, GABA, gamma aminobutyric acid, Slc27a1, long-chain fatty acid transport protein 1, nervous system, Fabp7, Mutation, Mag, myelin-associated glycoprotein, Gclc, glutamate--cysteine ligase catalytic subunit, Gsto1, glutathione S-transferase omega-1, Ephx1, epoxide hydrolase 1, Gpx1, glutathione peroxidase 1, C1qa, complement C1q subcomponent subunit A, MDD, major depressive disorder, Cd44, Cd44 antigen, Slc4a4, electrogenic sodium bicarbonate cotransporter 1, Neurodegenerative, Dlg4, disks large homolog 4, TIC, total ion current, Gstm1, glutathione S-transferase Mu 1, Alexander disease, 2.1 Biological and endogenous factors, Functional ability, Ndrg2, protein NDRG2, Sfxn5, sideroflexin-5, Ca2, carbonic anhydrase 2, S1pr1, sphingosine 1-phosphate receptor 1, Gpx3, glutathione peroxidase 3, Snap25, synaptosomal-associated protein 25, Sparcl1, SPARC-like protein 1, medicine.diagnostic_test, Prdx1, peroxiredoxin-1, medicine.anatomical_structure, Neurological, Pgd, 6-phosphogluconate dehydrogenase, decarboxylating, Mbp, myelin basic protein, LPA, lysophosphatidic acid, Astrocyte, Gss, glutathione synthetase, Stat3, signal transducer and activator of transcription 3, Biotechnology, Sorbs1, Sorbin and SH3 domain-containing protein 1, RFs, Rosenthal fibers, Pygb, glycogen phosphorylase, brain form, Ctsd, cathepsin D, Ddx3x, ATP-dependent RNA helicase DDX3X, Fasn, fatty acid synthase, Slc1a2, excitatory amino acid transporter 2, PPP, pentose phosphate pathway, Mice, Transgenic, Plpp3, phospholipid phosphatase 3, Biology, C1qb, complement C1q subcomponent subunit B, CNS, central nervous system, Gja1, gap junction alpha-1 protein, PRM-MS, parallel reaction monitoring-mass spectrometry, TFA, trifluoro acetic acid, Vim, vimentin, Rare Diseases, Western blot, Downregulation and upregulation, Acox1, peroxisomal acyl-coenzyme A oxidase 1, Mobp, myelin-associated oligodendrocyte basic protein, medicine, Atp1b2, sodium/potassium-transporting ATPase subunit beta-2, Animals, Cryab, alpha-crystallin B chain, MS2, MS/MS or tandem mass spectrometry, Research, Neurosciences, Molecular biology, Ntrk2, BDNF/NT-3 growth factors receptor, Brain Disorders, AxD, Alexander disease, Disease Models, Animal, Acox3, Peroxisomal acyl-coenzyme A oxidase 3, Disease Models, biology.protein, Ugp2, UTP--glucose-1-phosphate uridylyl transferase, Acot1, Acyl-coenzyme A thioesterase 1

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27db73f1a1ae5cb5705d0a860adbda89
https://hdl.handle.net/10919/111277

المؤلفون: Zhimin Yin, Qiyun Hang, Yang Yang, Lan Luo, Peng Cao, Xiaoliang Dong, Ling Li, Yuan Fang

المصدر: Redox Biology, Vol 20, Iss, Pp 157-166 (2019)
Redox Biology

مصطلحات موضوعية: Lipopolysaccharides, Male, 0301 basic medicine, iNOS, inducible nitric oxide synthases, Clinical Biochemistry, Anti-Inflammatory Agents, Intracellular Space, γ-GT, γ-glutamyltranspeptidase, Pharmacology, medicine.disease_cause, TNF-α, tumor necrosis factor-α, Biochemistry, Mice, chemistry.chemical_compound, 0302 clinical medicine, N-acetyl-L-cysteine, GSH, glutathione, LPS, Lipopolysaccharide, Nrf2, nuclear factor-erythroid 2-related factor, lcsh:QH301-705.5, NF-κB, nuclear factor-kappa B, NAC, N-acetyl-L-cysteine, chemistry.chemical_classification, lcsh:R5-920, biology, NF-kappa B, Dipeptides, COX-2, prostaglandin H2 synthase, Glutathione, Glutathione synthetase, CLP, cecal ligation and puncture, Tumor necrosis factor alpha, medicine.symptom, lcsh:Medicine (General), Research Paper, NF-E2-Related Factor 2, Inflammation, HMGB1, Models, Biological, Nitric oxide, 03 medical and health sciences, ROS, reactive oxygen species, CHX, cycloheximide, Sepsis, medicine, Animals, NO, nitric oxide, Reactive oxygen species, IL-1β, interleukin-1 beta, Organic Chemistry, GCL, γ-glutamylcysteine ligase, γ-glutamylcysteine, HMGB1, high mobility group box 1, Disease Models, Animal, Oxidative Stress, RAW 264.7 Cells, 030104 developmental biology, GSS, glutathione synthetase, chemistry, lcsh:Biology (General), γ-GC, γ-glutamylcysteine, biology.protein, Reactive Oxygen Species, 030217 neurology & neurosurgery, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae683ecc0cc66bb2849c7654b0119182
http://www.sciencedirect.com/science/article/pii/S221323171830836X

المؤلفون: Takeda H; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Ehime University, 454, Shitsukawa, Toon, Ehime, 791-0295, Japan.; Department of Gene Expression Regulation, Institute of Development, Aging and Cancer, Tohoku University, 4-1, Seiryo-cho, Aoba-ku, Sendai, Miyagi, 980-8575, Japan., Nakajima Y; Health and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 2 217-14, Hayashi-cho, Takamatsu, Kagawa, 761-0301, Japan., Yamaguchi T; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Ehime University, 454, Shitsukawa, Toon, Ehime, 791-0295, Japan., Watanabe I; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Ehime University, 454, Shitsukawa, Toon, Ehime, 791-0295, Japan., Miyoshi S; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Ehime University, 454, Shitsukawa, Toon, Ehime, 791-0295, Japan., Nagashio K; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Ehime University, 454, Shitsukawa, Toon, Ehime, 791-0295, Japan., Sekine H; Department of Gene Expression Regulation, Institute of Development, Aging and Cancer, Tohoku University, 4-1, Seiryo-cho, Aoba-ku, Sendai, Miyagi, 980-8575, Japan., Motohashi H; Department of Gene Expression Regulation, Institute of Development, Aging and Cancer, Tohoku University, 4-1, Seiryo-cho, Aoba-ku, Sendai, Miyagi, 980-8575, Japan., Yano H; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Ehime University, 454, Shitsukawa, Toon, Ehime, 791-0295, Japan., Tanaka J; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Ehime University, 454, Shitsukawa, Toon, Ehime, 791-0295, Japan.

المصدر: Journal of biochemistry [J Biochem] 2023 Jul 31; Vol. 174 (2), pp. 131-142.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0376600 Publication Model: Print Cited Medium: Internet ISSN: 1756-2651 (Electronic) Linking ISSN: 0021924X NLM ISO Abbreviation: J Biochem Subsets: MEDLINE

مواضيع طبية MeSH: NF-E2-Related Factor 2*/genetics , NF-E2-Related Factor 2*/metabolism , Bromisovalum*/pharmacology, Humans ; Mice ; Animals ; Kelch-Like ECH-Associated Protein 1/genetics ; Kelch-Like ECH-Associated Protein 1/metabolism ; Hypnotics and Sedatives/pharmacology ; Oxidative Stress ; Oxidation-Reduction ; Anti-Inflammatory Agents/pharmacology ; Inflammation/drug therapy