المؤلفون: Mbui, JM, Oluka, MN, Guantai, EM, Sinei, KA, Achieng, L, Baker, A, Jande, M, Massele, A, Godman, B

المصدر: Expert review of clinical pharmacology. 10(11):1263-1271

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:137109620

المؤلفون: Gacheri J; International Livestock Research Institute, Nairobi, Kenya.; Department of Pharmacology, Clinical Pharmacy and Pharmacy Practice, University of Nairobi, Nairobi, Kenya., Hamilton KA; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom., Munywoki P; International Livestock Research Institute, Nairobi, Kenya., Wakahiu S; International Livestock Research Institute, Nairobi, Kenya., Kiambi K; International Livestock Research Institute, Nairobi, Kenya., Fèvre EM; International Livestock Research Institute, Nairobi, Kenya.; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom., Oluka MN; Department of Pharmacology, Clinical Pharmacy and Pharmacy Practice, University of Nairobi, Nairobi, Kenya., Guantai EM; Department of Pharmacology, Clinical Pharmacy and Pharmacy Practice, University of Nairobi, Nairobi, Kenya., Moodley A; International Livestock Research Institute, Nairobi, Kenya.; Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg C, Denmark., Muloi DM; International Livestock Research Institute, Nairobi, Kenya.; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.

المصدر: PLOS global public health [PLOS Glob Public Health] 2024 Apr 25; Vol. 4 (4), pp. e0003046. Date of Electronic Publication: 2024 Apr 25 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 9918283779606676 Publication Model: eCollection Cited Medium: Internet ISSN: 2767-3375 (Electronic) Linking ISSN: 27673375 NLM ISO Abbreviation: PLOS Glob Public Health Subsets: PubMed not MEDLINE

المؤلفون: Bosc N; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, United Kingdom., Felix E; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, United Kingdom., Gardner JMF; AMG Consultants Ltd, Discovery Park House, Discovery Park, Sandwich, Kent CT13 9ND, United Kingdom., Mills J; Sandexis Medicinal Chemistry Ltd, Innovation House, Discovery Park, Sandwich, Kent CT13 9FF, United Kingdom., Timmerman M; Pivot Park Screening Centre, Pivot Park (Frederick Banting Building), Kloosterstraat 9, 5349 AB Oss, The Netherlands., Asveld D; Pivot Park Screening Centre, Pivot Park (Frederick Banting Building), Kloosterstraat 9, 5349 AB Oss, The Netherlands., Rensen K; Pivot Park Screening Centre, Pivot Park (Frederick Banting Building), Kloosterstraat 9, 5349 AB Oss, The Netherlands., Mukherjee P; TCG Life Sciences, Bengal Intelligent Park Limited, Block EP & GP, Salt Lake Electronics Complex, Sector V, Kolkata, West Bengal 700091, India., Das R; TCG Life Sciences, Bengal Intelligent Park Limited, Block EP & GP, Salt Lake Electronics Complex, Sector V, Kolkata, West Bengal 700091, India., Chenu E; Medicines for Malaria Ventures, 1215 Geneva, Switzerland., Besson D; Medicines for Malaria Ventures, 1215 Geneva, Switzerland., Burrows JN; Medicines for Malaria Ventures, 1215 Geneva, Switzerland., Duffy J; Medicines for Malaria Ventures, 1215 Geneva, Switzerland., Laleu B; Medicines for Malaria Ventures, 1215 Geneva, Switzerland., Guantai EM; Department of Pharmacy, Faculty of Health Sciences, University of Nairobi, 00202 Nairobi, Kenya., Leach AR; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, United Kingdom.

المصدر: ACS medicinal chemistry letters [ACS Med Chem Lett] 2023 Nov 20; Vol. 14 (12), pp. 1733-1741. Date of Electronic Publication: 2023 Nov 20 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

المؤلفون: Dechering KJ; TropIQ Health Sciences, Transistorweg 5, 6534 AT Nijmegen, The Netherlands., Timmerman M; Pivot Park Screening Centre, Oss, North Brabant, The Netherlands., Rensen K; Pivot Park Screening Centre, Oss, North Brabant, The Netherlands., Koolen KMJ; TropIQ Health Sciences, Transistorweg 5, 6534 AT Nijmegen, The Netherlands., Honarnejad S; Pivot Park Screening Centre, Oss, North Brabant, The Netherlands., Vos MW; TropIQ Health Sciences, Transistorweg 5, 6534 AT Nijmegen, The Netherlands., Huijs T; TropIQ Health Sciences, Transistorweg 5, 6534 AT Nijmegen, The Netherlands., Henderson RWM; TropIQ Health Sciences, Transistorweg 5, 6534 AT Nijmegen, The Netherlands., Chenu E; Medicines for Malaria Venture, Route de Pré-Bois 20, PO Box 1826, 1215 Geneva 15, Switzerland., Laleu B; Medicines for Malaria Venture, Route de Pré-Bois 20, PO Box 1826, 1215 Geneva 15, Switzerland., Montefiore BC; Optibrium, F5-6 Blenheim House, Cambridge Innovation Park, Denny End Road, Cambridge CB25 9PB, United Kingdom., Segall MD; Optibrium, F5-6 Blenheim House, Cambridge Innovation Park, Denny End Road, Cambridge CB25 9PB, United Kingdom., Mills JEJ; Sandexis Medicinal Chemistry Ltd, Innovation House, Discovery Park, Sandwich, CT13 9FF, United Kingdom., Guantai EM; Department of Pharmacy, Faculty of Health Sciences, University of Nairobi, 00202, Nairobi, Kenya., Duffy J; Medicines for Malaria Venture, Route de Pré-Bois 20, PO Box 1826, 1215 Geneva 15, Switzerland., Duffey M; Medicines for Malaria Venture, Route de Pré-Bois 20, PO Box 1826, 1215 Geneva 15, Switzerland. Electronic address: duffeym@mmv.org.

المصدر: SLAS discovery : advancing life sciences R & D [SLAS Discov] 2022 Sep; Vol. 27 (6), pp. 337-348. Date of Electronic Publication: 2022 Jul 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101697563 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2472-5560 (Electronic) Linking ISSN: 24725552 NLM ISO Abbreviation: SLAS Discov Subsets: MEDLINE

مواضيع طبية MeSH: Antimalarials*/pharmacology , Malaria*/drug therapy, Drug Discovery ; Humans ; Luciferases ; Plasmodium falciparum

المؤلفون: Nyabuti AO; Ministry of Health, Kisii County, Kenya., Okalebo FA; Department of Pharmacology and Pharmacognosy, University of Nairobi, Nairobi, Kenya., Guantai EM; Department of Pharmacology and Pharmacognosy, University of Nairobi, Nairobi, Kenya.

المصدر: Advances in pharmacological and pharmaceutical sciences [Adv Pharmacol Pharm Sci] 2020 Jun 19; Vol. 2020, pp. 3173847. Date of Electronic Publication: 2020 Jun 19 (Print Publication: 2020).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Hindawi Country of Publication: England NLM ID: 101762941 Publication Model: eCollection Cited Medium: Internet ISSN: 2633-4690 (Electronic) Linking ISSN: 26334690 NLM ISO Abbreviation: Adv Pharmacol Pharm Sci Subsets: PubMed not MEDLINE

المؤلفون: Ochola LA; Division of Pharmaceutics and Pharmacy Practice, School of Pharmacy, University of Nairobi, Nairobi, Kenya., Nyamu DG; Division of Pharmaceutics and Pharmacy Practice, School of Pharmacy, University of Nairobi, Nairobi, Kenya., Guantai EM; Division of Pharmacology, School of Pharmacy, University of Nairobi, Nairobi, Kenya., Weru IW; Kenyatta National Hospital, Nairobi, Kenya.

المصدر: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners [J Oncol Pharm Pract] 2020 Jun; Vol. 26 (4), pp. 823-834. Date of Electronic Publication: 2019 Sep 07.

نوع المنشور: Journal Article; Randomized Controlled Trial

بيانات الدورية: Publisher: SAGE Publications Country of Publication: England NLM ID: 9511372 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-092X (Electronic) Linking ISSN: 10781552 NLM ISO Abbreviation: J Oncol Pharm Pract Subsets: MEDLINE

مواضيع طبية MeSH: Hyperglycemia/*prevention & control , Hypoglycemic Agents/*administration & dosage , Metformin/*administration & dosage , Prednisone/*adverse effects, Adult ; Aged ; Blood Glucose/drug effects ; Fasting ; Female ; Hematologic Neoplasms/drug therapy ; Humans ; Hyperglycemia/chemically induced ; Kenya ; Male ; Middle Aged ; Postprandial Period ; Prednisone/therapeutic use ; Prospective Studies ; Young Adult

المؤلفون: Yaouba S; Department of Chemistry, University of Nairobi, P. O. Box 30197, 00100 Nairobi, Kenya. yaoubas@gmail.com., Valkonen A; Department of Chemistry, University of Jyvaskyla, P.O. Box 35, 40014 Jyvaskyla, Finland. arto.m.valkonen@jyu.fi., Coghi P; State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Macau 999078, China. coghips@must.edu.mo., Gao J; State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Macau 999078, China. cubix48@163.com., Guantai EM; Department of Pharmacology and Pharmacognosy, School of Pharmacy, University of Nairobi, P. O. Box 19676, 00202 Nairobi, Kenya. eguantai@uonbi.ac.ke., Derese S; Department of Chemistry, University of Nairobi, P. O. Box 30197, 00100 Nairobi, Kenya. sderese@uonbi.ac.ke., Wong VKW; State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Macau 999078, China. bowaiwong@gmail.com., Erdélyi M; Department of Chemistry⁻BMC, Uppsala University, Husargatan 3, 75237 Uppsala, Sweden. mate.erdelyi@kemi.uu.se.; The Swedish NMR Centre, Medicinaregatan 5, 40530 Gothenburg, Sweden. mate.erdelyi@kemi.uu.se.; Department of Chemistry and Molecular Biology, University of Gothenburg, 40530 Gothenburg, Sweden. mate.erdelyi@kemi.uu.se., Yenesew A; Department of Chemistry, University of Nairobi, P. O. Box 30197, 00100 Nairobi, Kenya. ayenesew@uonbi.ac.ke.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2018 Dec 04; Vol. 23 (12). Date of Electronic Publication: 2018 Dec 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules

مواضيع طبية MeSH: Asteraceae/*chemistry , Cell Survival/*drug effects , Diterpenes, Kaurane/*chemistry , Diterpenes, Kaurane/*pharmacology, A549 Cells ; Adenocarcinoma, Bronchiolo-Alveolar/drug therapy ; Adenocarcinoma, Bronchiolo-Alveolar/pathology ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/pathology ; Diterpenes, Kaurane/isolation & purification ; Hep G2 Cells ; Humans ; Liver Neoplasms/drug therapy ; Liver Neoplasms/pathology ; Lung Neoplasms/drug therapy ; Lung Neoplasms/pathology ; Molecular Structure ; Plant Components, Aerial/chemistry ; Plant Roots/chemistry

المؤلفون: Njogu PM; Department of Pharmaceutical Chemistry and ‡Division of Pharmacology, School of Pharmacy, University of Nairobi , P.O. Box 19676-00202, Nairobi, Kenya.; Department of Chemistry, ⊗Institute of Infectious Disease and Molecular Medicine, and ΘSouth African Medical Research Council Drug Discovery and Development Research Unit, University of Cape Town , Rondebosch 7701, South Africa., Guantai EM; Department of Pharmaceutical Chemistry and ‡Division of Pharmacology, School of Pharmacy, University of Nairobi , P.O. Box 19676-00202, Nairobi, Kenya.; Department of Chemistry, ⊗Institute of Infectious Disease and Molecular Medicine, and ΘSouth African Medical Research Council Drug Discovery and Development Research Unit, University of Cape Town , Rondebosch 7701, South Africa., Pavadai E; Department of Pharmaceutical Chemistry and ‡Division of Pharmacology, School of Pharmacy, University of Nairobi , P.O. Box 19676-00202, Nairobi, Kenya.; Department of Chemistry, ⊗Institute of Infectious Disease and Molecular Medicine, and ΘSouth African Medical Research Council Drug Discovery and Development Research Unit, University of Cape Town , Rondebosch 7701, South Africa., Chibale K; Department of Pharmaceutical Chemistry and ‡Division of Pharmacology, School of Pharmacy, University of Nairobi , P.O. Box 19676-00202, Nairobi, Kenya.; Department of Chemistry, ⊗Institute of Infectious Disease and Molecular Medicine, and ΘSouth African Medical Research Council Drug Discovery and Development Research Unit, University of Cape Town , Rondebosch 7701, South Africa.

المصدر: ACS infectious diseases [ACS Infect Dis] 2016 Jan 08; Vol. 2 (1), pp. 8-31. Date of Electronic Publication: 2015 Nov 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Drug Design*, Computer-Aided Design/*trends , Leishmaniasis/*drug therapy , Malaria/*drug therapy , Molecular Targeted Therapy/*trends , Trypanosomiasis/*drug therapy , Tuberculosis/*drug therapy, Antimalarials/chemistry ; Antiprotozoal Agents/chemistry ; Antitubercular Agents/chemistry ; Global Health ; Humans ; Program Development ; Structure-Activity Relationship

المؤلفون: Tacon C; Division of Pharmacology, University of Cape Town, Observatory 7925, South Africa., Guantai EM, Smith PJ, Chibale K

المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2012 Jan 15; Vol. 20 (2), pp. 893-902. Date of Electronic Publication: 2011 Dec 03.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Amino Alcohols/*chemistry , Amino Alcohols/*pharmacology , Antimalarials/*chemical synthesis , Antimalarials/*pharmacology , Diterpenes/*chemistry , Phenanthrenes/*chemical synthesis , Plasmodium falciparum/*drug effects , Propanolamines/*chemical synthesis, Abietanes ; Amino Alcohols/chemical synthesis ; Animals ; Antimalarials/chemistry ; CHO Cells ; Chloroquine/metabolism ; Cricetinae ; Cricetulus ; Phenanthrenes/chemistry ; Phenanthrenes/toxicity ; Propanolamines/chemistry ; Propanolamines/toxicity

المؤلفون: Feng TS; Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa., Guantai EM, Nell M, van Rensburg CE, Ncokazi K, Egan TJ, Hoppe HC, Chibale K

المصدر: Biochemical pharmacology [Biochem Pharmacol] 2011 Aug 01; Vol. 82 (3), pp. 236-47. Date of Electronic Publication: 2011 May 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Aminoquinolines/*pharmacology , Antimalarials/*pharmacology , Artemisinins/*pharmacology , Endocytosis/*drug effects , Hemeproteins/*metabolism , Plasmodium falciparum/*drug effects , Quinolines/*pharmacology, Aminoquinolines/chemistry ; Antimalarials/chemistry ; Artemisinins/chemistry ; Chlorquinaldol/chemistry ; Chlorquinaldol/pharmacology ; Molecular Structure ; Plasmodium falciparum/cytology ; Plasmodium falciparum/physiology ; Quinolines/chemistry