المؤلفون: Oliveira-Lopes AF; Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil., Götze MM; Graduate Studies Program in Biotechnology, University of Vale do Taquari-Univates, Lajeado, Brazil., Lopes-Neto BE; School of Veterinary Medicine, Ceará State University, Fortaleza, Brazil., Guerreiro DD; Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil., Bustamante-Filho IC; Graduate Studies Program in Biotechnology, University of Vale do Taquari-Univates, Lajeado, Brazil., Moura AA; Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil.

المصدر: Veterinary and comparative oncology [Vet Comp Oncol] 2024 Sep; Vol. 22 (3), pp. 340-358. Date of Electronic Publication: 2024 Jul 16.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Blackwell Country of Publication: England NLM ID: 101185242 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5829 (Electronic) Linking ISSN: 14765810 NLM ISO Abbreviation: Vet Comp Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Mammary Neoplasms, Animal*/pathology , Mammary Neoplasms, Animal*/genetics , Dog Diseases*/pathology , Dog Diseases*/genetics , Disease Models, Animal*, Dogs ; Animals ; Female ; Humans ; Breast Neoplasms/veterinary ; Breast Neoplasms/pathology ; Breast Neoplasms/genetics ; Translational Research, Biomedical

المؤلفون: Teles Filho ACA; Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil., Sanchez DJD; Laboratório de Biotecnologia, Universidad Cooperativa de Colombia, Bucaramanga, Colombia., Viana AGA; Department of Biology, Federal University of Viçosa, Viçosa, Brazil., Sheheryar S; Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil., Guerreiro DD; Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil., Bustamante-Filho IC; Laboratório de Biotecnologia, Universidade Do Vale Do Taquari, Lajeado, Brazil., Martins AMA; Laboratory of Protein Chemistry and Biochemistry, University of Brasília, Brasilia, Brazil., Sousa MV; Laboratory of Protein Chemistry and Biochemistry, University of Brasília, Brasilia, Brazil., Ricart CAO; Laboratory of Protein Chemistry and Biochemistry, University of Brasília, Brasilia, Brazil., Fontes W; Laboratory of Protein Chemistry and Biochemistry, University of Brasília, Brasilia, Brazil., Moura AA; Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil.

المصدر: Reproduction in domestic animals = Zuchthygiene [Reprod Domest Anim] 2024 Jul; Vol. 59 (7), pp. e14663.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Paul Parey Scientific Publishers Country of Publication: Germany NLM ID: 9015668 Publication Model: Print Cited Medium: Internet ISSN: 1439-0531 (Electronic) Linking ISSN: 09366768 NLM ISO Abbreviation: Reprod Domest Anim Subsets: MEDLINE

مواضيع طبية MeSH: Proteome* , Blastocyst*/metabolism, Animals ; Horses/embryology ; Female ; Embryonic Development ; Prospective Studies ; Proteomics ; Fertilization in Vitro/veterinary

المؤلفون: Viana Neto AM; Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil., Guerreiro DD; Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil., Martins JAM; School of Veterinary Medicine, Federal University of Cariri, Juazeiro do Norte, Brazil., Vasconcelos FÁR; Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil., Melo RÉBF; Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil., Velho ALMCS; Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil., Neila-Montero M; Itra-ULE, Animal Reproduction and Obstetrics, Department of Veterinary Medicine, Surgery and Anatomy, University of León, León, Spain., Montes-Garrido R; Itra-ULE, Animal Reproduction and Obstetrics, Department of Veterinary Medicine, Surgery and Anatomy, University of León, León, Spain., Nagano CS; Department of Fisheries Engineering, Federal University of Ceará, Fortaleza, Brazil., Araújo AA; Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil; School of Veterinary Medicine, Ceará State University, Fortaleza, Brazil., Moura AA; Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil. Electronic address: arlindo.moura@gmail.com.

المصدر: Animal reproduction science [Anim Reprod Sci] 2024 Apr; Vol. 263, pp. 107439. Date of Electronic Publication: 2024 Feb 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Scientific Pub. Co Country of Publication: Netherlands NLM ID: 7807205 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2232 (Electronic) Linking ISSN: 03784320 NLM ISO Abbreviation: Anim Reprod Sci Subsets: MEDLINE

مواضيع طبية MeSH: Semen*/physiology , Proteome*/metabolism, Male ; Sheep ; Animals ; Testis/physiology ; Sperm Motility ; Spermatozoa/physiology ; Sheep, Domestic

المؤلفون: Passos JRS; Laboratory of Animal Physiology, Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil., Guerreiro DD; Laboratory of Animal Physiology, Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil., Otávio KS; Laboratory of Animal Physiology, Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil., Dos Santos-Neto PC; Instituto de Reproducción Animal Uruguay, Fundación IRAUy, Montevideo, Uruguay., Souza-Neves M; Instituto de Reproducción Animal Uruguay, Fundación IRAUy, Montevideo, Uruguay., Cuadro F; Instituto de Reproducción Animal Uruguay, Fundación IRAUy, Montevideo, Uruguay., Nuñez-Olivera R; Instituto de Reproducción Animal Uruguay, Fundación IRAUy, Montevideo, Uruguay., Crispo M; Unidad de Biotecnología en Animales de Laboratorio, Institut Pasteur de Montevideo, Montevideo, Uruguay., Vasconcelos FR; Laboratory of Animal Physiology, Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil., Bezerra MJB; Laboratory of Animal Physiology, Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil., Silva RF; Laboratory of Manipulation of Oocyte and Preantral Follicles (LAMOFOPA), Ceará State University, Fortaleza, Brazil., Lima LF; Laboratory of Manipulation of Oocyte and Preantral Follicles (LAMOFOPA), Ceará State University, Fortaleza, Brazil., Figueiredo JR; Laboratory of Manipulation of Oocyte and Preantral Follicles (LAMOFOPA), Ceará State University, Fortaleza, Brazil., Bustamante-Filho IC; Laboratório de Biotecnologia, Universidade do Vale do Taquari, Lajeado, Brazil., Menchaca A; Instituto de Reproducción Animal Uruguay, Fundación IRAUy, Montevideo, Uruguay.; Plataforma de Investigación en Salud Animal, Instituto Nacional de Investigación Agropecuaria, Montevideo, Uruguay., Moura AA; Laboratory of Animal Physiology, Department of Animal Science, Federal University of Ceará, Fortaleza, Brazil.

المصدر: Molecular reproduction and development [Mol Reprod Dev] 2022 Oct; Vol. 89 (10), pp. 459-470. Date of Electronic Publication: 2022 Jul 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8903333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-2795 (Electronic) Linking ISSN: 1040452X NLM ISO Abbreviation: Mol Reprod Dev Subsets: MEDLINE

مواضيع طبية MeSH: Cumulus Cells*/metabolism , MicroRNAs*/metabolism, Sheep ; Animals ; Female ; Proteome/metabolism ; Sheep, Domestic ; Chromatography, Liquid ; Tandem Mass Spectrometry ; Oocytes/metabolism ; Ubiquitins/metabolism ; Ubiquitins/pharmacology ; Immunoglobulins/metabolism ; Macroglobulins/metabolism ; Macroglobulins/pharmacology ; In Vitro Oocyte Maturation Techniques/methods

المؤلفون: Ugur MR; IVF Michigan, Bloomfield Hills, MI, USA., Guerreiro DD; Departamento de Zootecnia, Universidade Federal do Ceará, Fortaleza, CE, Brasil., Moura AA; Departamento de Zootecnia, Universidade Federal do Ceará, Fortaleza, CE, Brasil.; Núcleo de Pesquisa e Desenvolvimento de Medicamentos, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE, Brasil., Memili E; Department of Animal and Dairy Sciences, Mississippi State University, Starkville, MS, USA.; Cooperative Agricultural Research Center, Prairie View A&M University, Prairie View, TX, USA.

المصدر: Animal reproduction [Anim Reprod] 2022 May 02; Vol. 19 (1), pp. e20220004. Date of Electronic Publication: 2022 May 02 (Print Publication: 2022).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Colégio Brasileiro de Reprodução Animal Country of Publication: Brazil NLM ID: 101272804 Publication Model: eCollection Cited Medium: Internet ISSN: 1984-3143 (Electronic) Linking ISSN: 18069614 NLM ISO Abbreviation: Anim Reprod Subsets: PubMed not MEDLINE

المؤلفون: Praxedes ÉCG; Laboratory on Animal Germplasm Conservation, Universidade Federal Rural Do Semi-Árido (UFERSA), BR 110, Km 47, Costa e Silva, 59625-900, Mossoró, RN, Brazil., Bezerra LGP; Laboratory on Animal Germplasm Conservation, Universidade Federal Rural Do Semi-Árido (UFERSA), BR 110, Km 47, Costa e Silva, 59625-900, Mossoró, RN, Brazil., Moreira SSJ; Laboratory on Animal Germplasm Conservation, Universidade Federal Rural Do Semi-Árido (UFERSA), BR 110, Km 47, Costa e Silva, 59625-900, Mossoró, RN, Brazil., Santos CS; Laboratory on Animal Germplasm Conservation, Universidade Federal Rural Do Semi-Árido (UFERSA), BR 110, Km 47, Costa e Silva, 59625-900, Mossoró, RN, Brazil., Brasil AV; Laboratory on Animal Germplasm Conservation, Universidade Federal Rural Do Semi-Árido (UFERSA), BR 110, Km 47, Costa e Silva, 59625-900, Mossoró, RN, Brazil., Silva AMD; Laboratory on Animal Germplasm Conservation, Universidade Federal Rural Do Semi-Árido (UFERSA), BR 110, Km 47, Costa e Silva, 59625-900, Mossoró, RN, Brazil., Guerreiro DD; Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculdade de Veterinária, Universidade Do Ceara, Av. Paranjana 1700, Campus Do Itaperi, 60714-903, Fortaleza, CE, Brazil., Pereira AF; Laboratory of Animal Biotechnology, UFERSA, BR 110, Km 47, Costa e Silva, 59625-900, Mossoró, RN, Brazil., Rodrigues APR; Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculdade de Veterinária, Universidade Do Ceara, Av. Paranjana 1700, Campus Do Itaperi, 60714-903, Fortaleza, CE, Brazil., Silva AR; Laboratory on Animal Germplasm Conservation, Universidade Federal Rural Do Semi-Árido (UFERSA), BR 110, Km 47, Costa e Silva, 59625-900, Mossoró, RN, Brazil. Electronic address: alexrs@ufersa.edu.br.

المصدر: Cryobiology [Cryobiology] 2021 Dec; Vol. 103, pp. 123-128. Date of Electronic Publication: 2021 Aug 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0006252 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2392 (Electronic) Linking ISSN: 00112240 NLM ISO Abbreviation: Cryobiology Subsets: MEDLINE

مواضيع طبية MeSH: Dasyproctidae* , Vitrification*, Animals ; Cryopreservation/methods ; Cryoprotective Agents/pharmacology ; Female ; Humans ; Ovarian Follicle ; Tissue Preservation

المؤلفون: Furtado RL; Graduate Program in Physiological Sciences, Higher Institute of Biomedical Sciences, State University of Ceará, Fortaleza, CE, 60714-903, Brazil., Martins JER; Institute of Physical Education and Sports, Federal University of Ceará, Fortaleza, CE, 60455760, Brazil., Oliveira MAF; Microscopy Laboratory of Health Sciences Center, State University of Ceará, Fortaleza, CE, 60714-903, Brazil., Guerreiro DD; Laboratory of Manipulation of Oocytes and Preantral Follicles, Veterinary Faculty, State University of Ceará, Fortaleza, CE, 60714-903, Brazil., de Sá NAR; Laboratory of Manipulation of Oocytes and Preantral Follicles, Veterinary Faculty, State University of Ceará, Fortaleza, CE, 60714-903, Brazil., Ferraz ASM; Institute of Physical Education and Sports, Federal University of Ceará, Fortaleza, CE, 60455760, Brazil., Ceccatto VM; Laboratory of Biochemistry and Gene Expression, Higher Institute of Biomedical Sciences, State University of Ceará, Fortaleza, CE, 60714-903, Brazil., Rodrigues APR; Laboratory of Manipulation of Oocytes and Preantral Follicles, Veterinary Faculty, State University of Ceará, Fortaleza, CE, 60714-903, Brazil., Araújo VR; Graduate Program in Physiological Sciences, Higher Institute of Biomedical Sciences, State University of Ceará, Fortaleza, CE, 60714-903, Brazil; and Microscopy Laboratory of Health Sciences Center, State University of Ceará, Fortaleza, CE, 60714-903, Brazil; and Corresponding author. Email: valdevane.araujo@gmail.com.

المصدر: Reproduction, fertility, and development [Reprod Fertil Dev] 2021 Oct; Vol. 33 (12), pp. 713-724.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Commonwealth Scientific and Industrial Research Organisation Country of Publication: Australia NLM ID: 8907465 Publication Model: Print Cited Medium: Internet ISSN: 1031-3613 (Print) Linking ISSN: 10313613 NLM ISO Abbreviation: Reprod Fertil Dev Subsets: MEDLINE

مواضيع طبية MeSH: Diet, High-Fat* , High-Intensity Interval Training*, Ovary/*metabolism , Oxidative Stress/*physiology , Physical Conditioning, Animal/*physiology, Adipose Tissue/metabolism ; Animals ; Catalase/metabolism ; Female ; Oxidation-Reduction ; Rats ; Rats, Wistar ; Superoxide Dismutase/metabolism

المؤلفون: Palomino GJQ; Faculty of Veterinary Medicine, Laboratory of Manipulation of Oocyte and Preantral Follicles (LAMOFOPA), State University of Ceará, Av. Dr. Silas Munguba, 1700, Fortaleza, CE, CEP: 60714-903, Brazil., Sá NAR; Faculty of Veterinary Medicine, Laboratory of Manipulation of Oocyte and Preantral Follicles (LAMOFOPA), State University of Ceará, Av. Dr. Silas Munguba, 1700, Fortaleza, CE, CEP: 60714-903, Brazil., Guerreiro DD; Faculty of Veterinary Medicine, Laboratory of Manipulation of Oocyte and Preantral Follicles (LAMOFOPA), State University of Ceará, Av. Dr. Silas Munguba, 1700, Fortaleza, CE, CEP: 60714-903, Brazil., Gomes FDR; Faculty of Veterinary Medicine, Laboratory of Manipulation of Oocyte and Preantral Follicles (LAMOFOPA), State University of Ceará, Av. Dr. Silas Munguba, 1700, Fortaleza, CE, CEP: 60714-903, Brazil., da Silva RF; Faculty of Veterinary Medicine, Laboratory of Manipulation of Oocyte and Preantral Follicles (LAMOFOPA), State University of Ceará, Av. Dr. Silas Munguba, 1700, Fortaleza, CE, CEP: 60714-903, Brazil., Lopes EPF; Faculty of Veterinary Medicine, Laboratory of Manipulation of Oocyte and Preantral Follicles (LAMOFOPA), State University of Ceará, Av. Dr. Silas Munguba, 1700, Fortaleza, CE, CEP: 60714-903, Brazil., Paes VM; Faculty of Veterinary Medicine, Laboratory of Manipulation of Oocyte and Preantral Follicles (LAMOFOPA), State University of Ceará, Av. Dr. Silas Munguba, 1700, Fortaleza, CE, CEP: 60714-903, Brazil., Gataí PHS; Laboratory of Phytochemical Analysis of Medicinal Plants (LAFIPLAN), Brazil., Alves BG; Postgraduate Program in Animal Bioscience, Federal University of Goias, Jatai, GO, Brazil., Pessoa ODL; Laboratory of Phytochemical Analysis of Medicinal Plants (LAFIPLAN), Brazil., Figueiredo JR; Faculty of Veterinary Medicine, Laboratory of Manipulation of Oocyte and Preantral Follicles (LAMOFOPA), State University of Ceará, Av. Dr. Silas Munguba, 1700, Fortaleza, CE, CEP: 60714-903, Brazil., Rocha RMP; University of International Integration of Afro-Brazilian Lusophony (UNILAB), Brazil., Rodrigues APR; Faculty of Veterinary Medicine, Laboratory of Manipulation of Oocyte and Preantral Follicles (LAMOFOPA), State University of Ceará, Av. Dr. Silas Munguba, 1700, Fortaleza, CE, CEP: 60714-903, Brazil. Electronic address: aprrodriguespapers@gmail.com.

المصدر: Reproductive toxicology (Elmsford, N.Y.) [Reprod Toxicol] 2021 Sep; Vol. 104, pp. 125-133. Date of Electronic Publication: 2021 Jul 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Pergamon In Cooperation With The Reproductive Toxicology Center Country of Publication: United States NLM ID: 8803591 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1708 (Electronic) Linking ISSN: 08906238 NLM ISO Abbreviation: Reprod Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*toxicity , Melatonin/*pharmacology , Protective Agents/*pharmacology , Withanolides/*toxicity, Animals ; Culture Media ; Female ; Oocytes ; Ovarian Follicle

المؤلفون: Mbemya GT; State University of Ceará, Faculty of Veterinary Sciences, LAMOFOPA, Fortaleza, CE, Brazil.; University of Dschang, Faculty of Science, Department of Biochemistry, URBPMAN, Dschang, Cameroon., Chekem MSG; University of Dschang, Faculty of Science, Department of Biochemistry, URBPMAN, Dschang, Cameroon., Lienou LL; University of Dschang, Faculty of Science, Department of Biochemistry, URBPMAN, Dschang, Cameroon., Sylvain NN; University of Dschang, Faculty of Science, Department of Biochemistry, URBPMAN, Dschang, Cameroon., Donfack JN; Free University of Brussels, Research Laboratory on Human Reproduction, Brussels, Belgium., Guerreiro DD; State University of Ceará, Faculty of Veterinary Sciences, LAMOFOPA, Fortaleza, CE, Brazil., Njimou JR; University of Ngaoundéré, School of Chemical Engineering and Mineral Industries, Ngaoundéré, Cameroon., Rodrigues APR; State University of Ceará, Faculty of Veterinary Sciences, LAMOFOPA, Fortaleza, CE, Brazil., Telefo PB; University of Dschang, Faculty of Science, Department of Biochemistry, URBPMAN, Dschang, Cameroon.

المصدر: Zygote (Cambridge, England) [Zygote] 2020 Dec; Vol. 28 (6), pp. 482-488. Date of Electronic Publication: 2020 Aug 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cambridge University Press Country of Publication: England NLM ID: 9309124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-8730 (Electronic) Linking ISSN: 09671994 NLM ISO Abbreviation: Zygote Subsets: MEDLINE

مواضيع طبية MeSH: Sexual Maturation*, Animals ; Female ; Gonadotropins, Equine ; Horses ; Ovary ; Pregnancy ; Rats ; Reproduction ; Uterus

المؤلفون: Ferreira ACA; Laboratory of Manipulation of Oocytes and Preantral Follicles, Faculty of Veterinary, State University of Ceará, Fortaleza, CE, Brazil., Sá NAR; Laboratory of Manipulation of Oocytes and Preantral Follicles, Faculty of Veterinary, State University of Ceará, Fortaleza, CE, Brazil., Cadenas J; Laboratory of Reproductive Biology, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark., Correia HHV; Laboratory of Manipulation of Oocytes and Preantral Follicles, Faculty of Veterinary, State University of Ceará, Fortaleza, CE, Brazil., Guerreiro DD; Laboratory of Manipulation of Oocytes and Preantral Follicles, Faculty of Veterinary, State University of Ceará, Fortaleza, CE, Brazil., Alves BG; Postgraduate Program in Animal Bioscience, Federal University of Goiás, Jataí, GO, Brazil., Lima LF; Laboratory of Manipulation of Oocytes and Preantral Follicles, Faculty of Veterinary, State University of Ceará, Fortaleza, CE, Brazil., Celestino JJH; Institute of Health Sciences, University of International Integration of Afro-Brazilian Lusophony, Acarape, CE, Brazil., Rodrigues APPR; Laboratory of Manipulation of Oocytes and Preantral Follicles, Faculty of Veterinary, State University of Ceará, Fortaleza, CE, Brazil., Gastal EL; Department of Animal Science, Food and Nutrition, Southern Illinois University, Carbondale, IL, United States., Figueiredo JR; Laboratory of Manipulation of Oocytes and Preantral Follicles, Faculty of Veterinary, State University of Ceará, Fortaleza, CE, Brazil. Electronic address: jrf.lamofopapapers@gmail.com.

المصدر: Animal reproduction science [Anim Reprod Sci] 2020 Aug; Vol. 219, pp. 106461. Date of Electronic Publication: 2020 Apr 25.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: Elsevier Scientific Pub. Co Country of Publication: Netherlands NLM ID: 7807205 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2232 (Electronic) Linking ISSN: 03784320 NLM ISO Abbreviation: Anim Reprod Sci Subsets: MEDLINE

مواضيع طبية MeSH: Goats*/genetics , Goats*/metabolism , Oogenesis*/drug effects , Oogenesis*/genetics, Follicle Stimulating Hormone/*pharmacology , Ovarian Follicle/*drug effects , RNA, Messenger/*drug effects, Animals ; Cattle ; Cells, Cultured ; Culture Media/chemistry ; Culture Media/pharmacology ; Female ; Follicle Stimulating Hormone/metabolism ; Gene Expression Regulation/drug effects ; Humans ; In Vitro Oocyte Maturation Techniques/methods ; In Vitro Oocyte Maturation Techniques/veterinary ; Oocytes/cytology ; Oocytes/drug effects ; Oocytes/physiology ; Ovarian Follicle/cytology ; Ovarian Follicle/physiology ; Ovulation/drug effects ; Ovulation/genetics ; Pituitary Gland/metabolism ; RNA, Messenger/metabolism ; Random Allocation ; Recombinant Proteins/pharmacology ; Species Specificity ; Swine