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1
المؤلفون: Karen Rowland Yeo, Bo Liu, Mahmut Özdemir, Geoffrey T. Tucker, H. Kim Crewe, Amin Rostami-Hodjegan
المصدر: Biopharmaceutics & Drug Disposition. 38:260-270
مصطلحات موضوعية: Pharmacology, Physiologically based pharmacokinetic modelling, Chemistry, Cmax, Pharmaceutical Science, General Medicine, Absorption (skin), Metabolism, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, 030220 oncology & carcinogenesis, medicine, Midazolam, Pharmacology (medical), Absorption kinetics, Ketoconazole, medicine.drug
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2
المؤلفون: Howard Burt, Matthew D Harwood, Sibylle Neuhoff, Katherine L. Gill, H. Kim Crewe, Arian Emami Riedmaier
المصدر: Drug Metabolism and Disposition
مصطلحات موضوعية: Pharmacology, Genetics, Liver-Specific Organic Anion Transporter 1, Coefficient of variation, Pharmaceutical Science, Transporter, Articles, Biology, 030226 pharmacology & pharmacy, Phenotype, White People, Multiple drug resistance, Solute Carrier Organic Anion Transporter Family Member 1B3, 03 medical and health sciences, 0302 clinical medicine, Liver, Abundance (ecology), 030220 oncology & carcinogenesis, Meta-analysis, Genotype, Humans, Geometric mean
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b20acf484bdeb6da46069d97924af1d
https://doi.org/10.1124/dmd.116.071183 -
3
المؤلفون: Bo, Liu, H Kim, Crewe, Mahmut, Ozdemir, Karen, Rowland Yeo, Geoffrey, Tucker, Amin, Rostami-Hodjegan
المصدر: Biopharmaceuticsdrug disposition. 38(3)
مصطلحات موضوعية: Adult, Gastrointestinal Tract, Male, Ketoconazole, Dose-Response Relationship, Drug, Liver, Midazolam, Humans, Drug Interactions, Female, Middle Aged, Models, Biological, Drug Administration Schedule
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4
المؤلفون: H. Kim Crewe, Martin S. Lennard, Elizabeth M. J. Gillam, R. M. Wunsch, L. Notley
المصدر: Drug Metabolism and Disposition. 30:869-874
مصطلحات موضوعية: Antineoplastic Agents, Hormonal, Metabolite, Pharmaceutical Science, In Vitro Techniques, Biology, Hydroxylation, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, medicine, Humans, skin and connective tissue diseases, Chromatography, High Pressure Liquid, Active metabolite, Demethylation, Pharmacology, 4-hydroxytamoxifen, Cytochrome P450, Stereoisomerism, Antiestrogen, Isoenzymes, Tamoxifen, chemistry, Biochemistry, Microsomes, Liver, Microsome, biology.protein, hormones, hormone substitutes, and hormone antagonists, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2335ce0225279db9037e2f516744aceb
https://doi.org/10.1124/dmd.30.8.869 -
5
المصدر: Drug metabolism and pharmacokinetics. 23(2)
مصطلحات موضوعية: Quinidine, medicine.medical_specialty, CYP2D6, Enclomiphene, Pharmaceutical Science, Biology, Pharmacology, digestive system, Clomiphene, Anovulation, Internal medicine, medicine, Cytochrome P-450 CYP3A, Humans, Pharmacology (medical), skin and connective tissue diseases, CYP3A4, Zuclomiphene, Metabolism, medicine.disease, Endocrinology, Ketoconazole, Cytochrome P-450 CYP2D6, Microsome, Microsomes, Liver, Tamoxifen, medicine.drug
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المؤلفون: Martin S. Lennard, H. Kim Crewe, S.Wynne Ellis, Geoffrey T. Tucker
المصدر: Biochemical pharmacology. 53(2)
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Antineoplastic Agents, Hormonal, Hydroxylation, Biochemistry, Mixed Function Oxygenases, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Internal medicine, Cytochrome P-450 CYP3A, medicine, Humans, Pharmacology, biology, CYP3A4, Cytochrome P450, Middle Aged, Antiestrogen, Tamoxifen, Endocrinology, chemistry, Cytochrome P-450 CYP2D6, Steroid 16-alpha-Hydroxylase, Dealkylation, Steroid Hydroxylases, biology.protein, Microsome, Microsomes, Liver, Female, Aryl Hydrocarbon Hydroxylases, medicine.drug