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1
المؤلفون: Sue H. Kadwell, Domanico Pl, J. D. Stuart, G. Tian, Marcia L. Moss, T. A. Kost, L. K. Overton, Robert A. Mook, I R Patel, H. N. Bramson
المصدر: Biochemistry. 33:2291-2296
مصطلحات موضوعية: chemistry.chemical_classification, Reaction mechanism, Binding Sites, biology, Stereochemistry, medicine.medical_treatment, Finasteride, Active site, Alpha (ethology), Biochemistry, Steroid, Kinetics, 5 Alpha-Reductase Inhibitor, chemistry.chemical_compound, 5-alpha Reductase Inhibitors, Enzyme, chemistry, Enzyme inhibitor, biology.protein, medicine, Humans
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2
المؤلفون: H. N. Bramson, Kenneth Batchelor, J. E. Long, Roger N. Hiner, Frank Lee, Marcia L. Moss, R. A. Jun. Mook, J. D. Stuart, J. Van Arnold, Stephen V. Frye, Stephanie L. Schweiker, Mary K. Grizzle, Curt D. Haffner, Michael K. James, Timothy K. Tippin, G. Tian, Patrick R. Maloney, S V Schuster, D. M. Bickett, Rayomand J. Unwalla, G. F. Jun. Dorsey
المصدر: ChemInform. 25
مصطلحات موضوعية: Azasteroids, Biochemistry, Chemistry, medicine.medical_treatment, medicine, General Medicine, 5 alpha reductase, Human type, Steroid
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3
المؤلفون: J. Van Arnold, Kenneth Batchelor, J. D. Stuart, Stephanie L. Schweiker, D. M. Bickett, Robert Carl Andrews, Wheeler Thomas Neil, Stephen V. Frye, Frank Lee, R. A. Jun. Mook, R. N. Hiner, Patrick R. Maloney, Curt D. Haffner, John A. Ray, G. F. Jun. Dorsey, H. N. Bramson, G. Tian, Rayomand J. Unwalla, Marcia L. Moss, Cynthia Markert Cribbs, S. Croom
المصدر: ChemInform. 25
مصطلحات موضوعية: Steroid dehydrogenase, Azasteroids, Biochemistry, Chemistry, medicine.medical_treatment, medicine, General Medicine, Isomerase, 5α reductase, Steroid
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4
المؤلفون: L M Regan, H N Bramson, C Sommers, H Nachod, J E Casnellie
المصدر: Journal of Biological Chemistry. 266:16219-16225
مصطلحات موضوعية: Tyrosine phosphorylation, Cell Biology, Biology, Biochemistry, Angiotensin II, Cell biology, Phosphotransferase, chemistry.chemical_compound, chemistry, Cell surface receptor, Phosphorylation, Tyrosine, Protein kinase A, Molecular Biology, Tyrosine kinase
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4933cddc4f3dff9ce87407645e552abf
https://doi.org/10.1016/s0021-9258(18)98538-8 -
5
المؤلفون: James Marvin Veal, William D. Holmes, Valerie G. Montana, Lee F. Kuyper, Mark P. Edelstein, B. Lovejoy, Stephen T. Davis, Michael Joseph Luzzio, Robert T. Gampe, Philip A. Harris, Karen Lackey, H. N. Bramson, Scott Howard Dickerson, Stephen V. Frye, David W. Rusnak, Duncan Herrick Walker, A.M. Hassell, J. Corona, Robert N. Hunter, Lisa M. Shewchuk, Warren J. Rocque
المصدر: Journal of medicinal chemistry. 44(25)
مصطلحات موضوعية: Isatin, Models, Molecular, Indoles, Stereochemistry, Antineoplastic Agents, Protein Serine-Threonine Kinases, Crystallography, X-Ray, Chemical synthesis, S Phase, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, CDC2-CDC28 Kinases, Tumor Cells, Cultured, Structure–activity relationship, Humans, Oxindole, Enzyme Inhibitors, Cyclin-dependent kinase 1, Sulfonamides, biology, Cyclin-dependent kinase 2, Cyclin-Dependent Kinase 2, G1 Phase, Hydrazones, Stereoisomerism, Cyclin-Dependent Kinases, Enzyme binding, Crystallography, Biochemistry, chemistry, Docking (molecular), biology.protein, Molecular Medicine, Drug Screening Assays, Antitumor, Lead compound, Protein Binding
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6
المؤلفون: J D, Stuart, F W, Lee, D, Simpson Noel, S H, Kadwell, L K, Overton, C R, Hoffman, T A, Kost, T K, Tippin, R L, Yeager, K W, Batchelor, H N, Bramson
المصدر: Biochemical pharmacology. 62(7)
مصطلحات موضوعية: Male, Insecta, Time Factors, Finasteride, Dutasteride, Transfection, Binding, Competitive, Rats, Rats, Sprague-Dawley, Kinetics, 5-alpha Reductase Inhibitors, 3-Oxo-5-alpha-Steroid 4-Dehydrogenase, Azasteroids, Animals, Testosterone, Enzyme Inhibitors, Cells, Cultured
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7
المؤلفون: S V, Frye, H N, Bramson, D J, Hermann, F W, Lee, A K, Sinhababu, G, Tian
المصدر: Pharmaceutical biotechnology. 11
مصطلحات موضوعية: Isoenzymes, Cholestenone 5 alpha-Reductase, Dose-Response Relationship, Drug, Azasteroids, Finasteride, Animals, Humans, Dihydrotestosterone, Dutasteride, Enzyme Inhibitors, Oxidoreductases
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::f02c8b4b06b619f19bb6f0f8d889da38
https://pubmed.ncbi.nlm.nih.gov/9760689 -
8
المؤلفون: H N, Bramson, D, Hermann, K W, Batchelor, F W, Lee, M K, James, S V, Frye
المصدر: The Journal of pharmacology and experimental therapeutics. 282(3)
مصطلحات موضوعية: Male, Cholestenone 5 alpha-Reductase, Dose-Response Relationship, Drug, Finasteride, Dutasteride, Rats, Rats, Sprague-Dawley, Dogs, Azasteroids, Animals, Humans, Enzyme Inhibitors, Rats, Wistar, Oxidoreductases, Half-Life
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::58b3f8270b9edb78d5c9fad0b39a0831
https://pubmed.ncbi.nlm.nih.gov/9316864 -
9
المؤلفون: S V, Frye, C D, Haffner, P R, Maloney, R A, Mook, G F, Dorsey, R N, Hiner, K W, Batchelor, H N, Bramson, J D, Stuart, S L, Schweiker
المصدر: Journal of medicinal chemistry. 36(26)
مصطلحات موضوعية: Azasteroids, Male, medicine.medical_treatment, Pharmacology, Moths, Transfection, Steroid, Cell Line, Rats, Sprague-Dawley, 5 Alpha-Reductase Inhibitor, chemistry.chemical_compound, 5-alpha Reductase Inhibitors, Drug Discovery, medicine, Animals, Humans, Testosterone, biology, Chemistry, Dihydrotestosterone, Recombinant Proteins, Rats, Isoenzymes, Enzyme inhibitor, Cell culture, biology.protein, Finasteride, Molecular Medicine, Baculoviridae, Orchiectomy, medicine.drug
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10
المؤلفون: H N, Bramson, J E, Casnellie, H, Nachod, L M, Regan, C, Sommers
المصدر: The Journal of biological chemistry. 266(24)
مصطلحات موضوعية: Antigens, Differentiation, T-Lymphocyte, Cytoplasm, Angiotensin II, CD8 Antigens, Molecular Sequence Data, Osmolar Concentration, Protein-Tyrosine Kinases, Peptide Mapping, Catalysis, Substrate Specificity, Enzyme Activation, Kinetics, Lymphocyte Specific Protein Tyrosine Kinase p56(lck), Cations, CD4 Antigens, Trypsin, Amino Acid Sequence, Phosphorylation
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::9af54c766ef636e0b04fac3fe8c03727
https://pubmed.ncbi.nlm.nih.gov/1908465