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1دورية أكاديمية
المؤلفون: Dan Liang, Lu Liu, Yunjie Zhao, Zhenyi Luo, Yadi He, Yanping Li, Shiyun Tang, Jianyuan Tang, Nianzhi Chen
المصدر: Frontiers in Pharmacology, Vol 14 (2023)
مصطلحات موضوعية: TME, tumor microenvironment, ECM, extracellular matrix, CAFs, cancer-associated fibroblasts, TAMs, tumor-associated macrophages, HA, hyaluronic acid, MMPs, matrix metalloproteinases, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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المؤلفون: Paula Pleguezuelos-Beltrán, Patricia Gálvez-Martín, Daniel Nieto-García, Juan Antonio Marchal, Elena López-Ruiz
المصدر: Digibug. Repositorio Institucional de la Universidad de Granada
instnameمصطلحات موضوعية: CEA, cultured epithelial autograft, GELATIN SCAFFOLDS, CAT, Committee for Advances Therapies, PRP, platelet rich plasma, Biomedical Engineering, APPLIED CELL THERAPY, BLA, Biologic License Application, CHMP, Committee for Medicinal Product for Human Use, PHSA, Public Health Service Act, GAGs, glycosaminoglycans, OTAT, Office of Tissues and Advanced Therapies, Biomaterials, Spray, PU, polyurethane, ATMP, advanced therapy medicinal product, DMEM, Dulbecco's Modified Eagle's medium, EU, European Union, NP, Notified body, Tissue engineering, MA, marketing authorization, HA, hyaluronic acid, USA, United States of America, PEG, polyethylene glycol, Skin, Fibrin, PMA, Premarket Approval, FIBRIN SEALANT, FULL-THICKNESS WOUNDS, PRF, platelet rich fibrin, HUMAN ALLOGENEIC FIBROBLASTS, HYALURONIC-ACID, IN-VITRO, GLP, Good Laboratory Practice, HCT/Ps, human cells, tissues, and cellular and tissue-based products, PCL, polycaprolactone, FDA, Food and Drug Administration, QMS, Quality Management System, TE, tissue engineering, ECM, extracellular matrix, EPIDERMAL-CELLS, Hydrogel, GMP, Good Manufacturing Practice, CFR, Code of Federal Regulations, CTD, Common Technical Document, VENOUS LEG ULCERS, EMA, European Medicines Agency, ISO, International Organization for Standardization, Biotechnology, CULTURED EPITHELIAL AUTOGRAFTS
وصف الملف: application/pdf
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المؤلفون: Shixing Huang, Hongpeng Shi, Xiaofeng Ye, Qiang Zhao, Qi Yang, Mingliang Wang, Chenyu Jiang, Mi Zhou, Bei Qian, Qiang Long
المصدر: Bioactive Materials, Vol 7, Iss, Pp 401-411 (2022)
Bioactive Materialsمصطلحات موضوعية: QH301-705.5, Angiogenesis, PRP, platelet rich plasma, 0206 medical engineering, SUV, standardized uptake value, Biomedical Engineering, Macrophage polarization, BZ, border zone, 02 engineering and technology, Pharmacology, Article, Fibrin, Biomaterials, chemistry.chemical_compound, TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick-end labeling, Hyaluronic acid, Biology (General), HA, hyaluronic acid, Materials of engineering and construction. Mechanics of materials, PRF, platelet-rich fibrin, LVEDd, left ventricular end-diastolic diameter, Injectable hydrogel, biology, Lyophilized platelet-rich fibrin, Chemistry, Vascularization, LVEF, left ventricular ejection fractions, 021001 nanoscience & nanotechnology, 020601 biomedical engineering, Platelet-rich fibrin, IZ, infarcted zone, Myocardial infarction, ALG, alginate, Ly-PRF, lyophilized platelet-rich fibrin, Drug delivery, Self-healing hydrogels, MI, myocardial infarction, iNOS, inducible nitric oxide synthase, TA401-492, biology.protein, Myocardial fibrosis, LVFS, left ventricular fractional shortening, LVESd, left ventricular end-systolic diameter, 0210 nano-technology, PET-CT, positron emission tomography-computerized tomography, Biotechnology
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المؤلفون: Kaneez Fatima, Abha Meena, Suaib Luqman, Nusrat Masood, Zahoor Ahmad Wani
المصدر: Journal of Advanced Research
مصطلحات موضوعية: TRIG, Triglyceraldehyde, Skin Neoplasms, Cell, DOXO, Doxorubicin, Hyaluronidase, Pharmacology, NaOH, Sodium hydroxide, Polymerization, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Mice, 0302 clinical medicine, BIL, Bilirubin total & direct, Neomenthol, PEP A, pepstatin A, Cancer biomarker, MEF, Mean erythrocyte fragility, HYAL, Hyaluronidase, PBS, Phosphate buffer saline, CM-H2DCFDA, Chloromethyl derivative of dichloro fluorescin diacetate, HA, Hyaluronic acid, Epidermoid carcinoma, Human epidermoid carcinoma, 030220 oncology & carcinogenesis, RBC, Red blood cell, DMEM, Dulbecco’s minimal essential media, SRB, Sulphorhodamine B, BUN, Blood urea nitrogen, FACS, Fluorescence-Activated Cell Sorting, AKLP, Alkaline phosphatase, Hyaluronoglucosaminidase, NADPH, Nicotinamide adenine dinucleotide phosphate hydrogen, TMPD, N,N,N′,N′-tetramethyl-p-phenylenediamine, Article, 03 medical and health sciences, In vivo, Ehrlich Ascites Carcinoma, BE, Binding energy, Humans, CATD, Cathepsin D, LDH, Lactate dehydrogenase, COX-2, Cyclooxygenase 2, FOX, Ferrous oxidation-xylenol orange, DMSO, Dimethyl sulfoxide, mTOR, Mammalian target of rapamycin, In vitro, Ab/Am, Antibiotic/antimycotic, NRU, Neutral red uptake, EC50, Half maximal effective concentration, 030104 developmental biology, IC50, Half maximal inhibitory concentration, EAC, Ehlrich Ascites Carcinoma, RPMI, Roswell park memorial institute, ROS, Reactive oxygen species, 0301 basic medicine, HDL, High density lipoprotein, TNBS, Trinitrobenzenesulphonic acid, PI3K, Phosphotidyl inositol-3 kinase, URIC, Uric acid, DNA, Deoxyribonucleic acid, GAPDH, Glyceraldehyde 3-phosphate dehydrogenase, HEPES, N-2-hydroxyethylpiperazine-N′-2-ethanesulfonic acid, Tubulin, OECD, Organization for Economic Co-operation and Development, SGPT, Alanine aminotransferase, LOX-5, Lipoxygenase-5, DFMO, α-difluoro methyl ornithine, Multidisciplinary, WBC, White blood cell, Chemistry, ELISA, enzyme-linked immunosorbent assay, PKB/Akt, Protein kinase B, AA, Arachidonic acid, RNase A, Ribonuclease A, TPR, Total protein, Molecular Docking Simulation, medicine.anatomical_structure, TCA, Tricarboxylic acid, CHOL, Cholesterol, Ki, Inhibitory constant, medicine.drug, ODC, Ornithine decarboxylase, DHFR, Dihydrofolatereductase, BSA, Bovine serum albumin, PDB, Protein Data Bank, medicine, Animals, MMP, Mitochondrial membrane potential, DCFDA, 2′,7′ dichloro fluorescin diacetate, RNA, Ribonucleic acid, RIPA, Radio immune precipitation assay buffer, EDTA, Ethylene diamine tetra acetic acid, IC50, TPA, 12-O-Tetradecanoylphorbol-13-acetate, ComputingMethodologies_COMPUTERGRAPHICS, TRPM8, Transient receptor potential member 8, Cell Proliferation, HDAC, Histone deacetylase, MTX, Methotrexate, OF, Osmotic fragility, PI, Propidium iodide, FDA, Food and Drug Administration, HEK293 Cells, PDT, Podophyllotoxin, Cell culture, NAC, N-acetyl cysteine, SGOT, Aspartate aminotransferase, CRTN, Creatinine, FBS, Fetal bovine serum, PCR, Polymerase chain reaction, Rh123, Rhodamine 123, Ex vivo, IDT, Integrated DNA Technologies
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المؤلفون: Yihui Yang, Xiangjin Zheng, Sha Li, Jinyi Liu, Wan Li, Jie Yi, Weiqi Fu, Jinhua Wang, Guanhua Du, Liwen Ren
المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2783-2797 (2021)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: MSC, mesenchymal stem cells, MDSCs, myeloid-derived suppressor cells, Angiogenesis, PDAC, pancreatic ductal adenocarcinoma, Cell, Review, Exosomes, hTERT, human telomerase reverse transcriptase, Metastasis, PCC, pheochromocytoma, HTR, hormone therapy-resistant, 0302 clinical medicine, DNM3, dynamin 3, DC, dendritic cells, miRNA, microRNA, Tumor immunity, CDH3, cadherin 3, NKEXOs, natural killer cell-derived exosomes, PA, phosphatidic acid, CD-UPRT, cytosine deaminase-uracil phosphoribosyltransferase, General Pharmacology, Toxicology and Pharmaceutics, HA, hyaluronic acid, HIF1, hypoxia-inducible factor 1, 0303 health sciences, PS, phosphatidylserine, ECM, extracellular matrix, medicine.anatomical_structure, PGL, paraganglioma, circRNAs, circular RNAs, 030220 oncology & carcinogenesis, CRC, colorectal cancer, MVB, multivesicular body, Drug delivery, APCs, antigen-presenting cells, RCC, renal cell carcinoma, ESCRT, endosomal sorting complex required for transport, Signal transduction, DLBCL, diffuse large B-cell lymphoma, EMT, epithelial–mesenchymal transition, ILVs, intraluminal vesicles, HUVECs, human umbilical vein endothelial cells, PD-L1, programmed cell death receptor ligand 1, CCRCC, clear-cell renal cell carcinoma, Del-1, developmental endothelial locus-1, TSG101, tumor susceptibility gene 101, RM1-950, ABCA3, ATP-binding cassette transporter A3, Biology, PI, phosphatidylinositol, 03 medical and health sciences, Immune system, DEXs, DC-derived exosomes, NSCLC, non-small cell lung cancer, MIF, migration inhibitory factor, medicine, PTRF, polymerase I and transcript release factor, 030304 developmental biology, GPC1, glypican-1, SM, sphingomyelin, lncRNAs, long non-coding RNAs, Cancer, NNs, nanoparticles, medicine.disease, TEX, tumor-derived exosomes, Microvesicles, mtDNA, mitochondrial DNA, SNARE, soluble NSF-attachment protein receptor, Drug resistance, lamp2b, lysosome-associated membrane glycoprotein 2b, ncRNA, non-coding RNAs, Cancer research, dsDNA, double stranded DNA, Therapeutics. Pharmacology, HCC, hepatocellular carcinoma, Tumor metastasis, Biomarkers, CAFs, cancer-associated fibroblasts
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المؤلفون: Xianqun Fan, Jipeng Li, Muyue Yang, Ping Gu
المصدر: Bioactive Materials
Bioactive Materials, Vol 6, Iss 7, Pp 1973-1987 (2021)مصطلحات موضوعية: MDSCs, myeloid-derived suppressor cells, medicine.medical_treatment, PLGA, poly(lactic-co-glycolic acid), Cancer immunotherapy, BTK, Bruton's tyrosine kinase, 02 engineering and technology, CAFs, cancer associated fibroblasts, CCL, chemoattractant chemokines ligand, DSF/Cu, disulfiram/copper, melittin-NP, melittin-lipid nanoparticle, IFN-γ, interferon-γ, TNF-α, tumor necrosis factor alpha, ANG2, angiopoietin-2, Hypoxia, lcsh:QH301-705.5, cDCs, conventional dendritic cells, TME, tumor microenvironment, DMXAA, 5,6-dimethylxanthenone-4-acetic acid, HB-GFs, heparin-binding growth factors, M2NP, M2-like TAM dual-targeting nanoparticle, ECM, extracellular matrix, IFP, interstitial fluid pressure, HIF, hypoxia-inducible factor, Tumor microenvironment, PDT, photodynamic therapy, Tregs, regulatory T cells, tdLNs, tumor-draining lymph nodes, 0210 nano-technology, Ab, antibodies, BBB, blood-brain barrier, DMMA, 2,3-dimethylmaleic anhydrid, SA, sialic acid, FDA, the Food and Drug Administration, PS, photosensitizer, Biomedical Engineering, Ag, antigen, Article, PD-1, programmed cell death protein 1, Biomaterials, TAMs, tumor-associated macrophages, lcsh:TA401-492, FAP, fibroblast activation protein, EPR, enhanced permeability and retention, NPs, nanoparticles, MPs, microparticles, NO, nitric oxide, Tumor therapy, scFv, single-chain variable fragment, medicine.disease, IL, interleukin, Radiation therapy, siRNA, small interfering RNA, Nanoparticles, TDPA, tumor-derived protein antigens, lcsh:Materials of engineering and construction. Mechanics of materials, HSA, human serum albumin, RLX, relaxin-2, Bcl-2, B-cell lymphoma 2, PSCs, pancreatic stellate cells, VDA, vasculature disrupting agent, Photodynamic therapy, CaCO3, calcium carbonate, Metastasis, AuNCs, gold nanocages, CTLA4, cytotoxic lymphocyte antigen 4, HPMA, N-(2-hydroxypropyl) methacrylamide, HA, hyaluronic acid, TIM-3, T cell immunoglobulin domain and mucin domain-3, TGF-β, transforming growth factor β, UPS-NP, ultra-pH-sensitive nanoparticle, IBR, Ibrutinib, MCMC, mannosylated carboxymethyl chitosan, α-SMA, alpha-smooth muscle actin, 021001 nanoscience & nanotechnology, VEGF, vascular endothelial growth factor, TAAs, tumor-associated antigens, LPS, lipopolysaccharide, APCs, antigen-presenting cells, Delivery system, DCs, dendritic cells, NF-κB, nuclear factor κB, PHDs, prolyl hydroxylases, EMT, epithelial-mesenchymal transition, TLR, Toll-like receptor, Biotechnology, PFC, perfluorocarbon, 0206 medical engineering, CAP, cleavable amphiphilic peptide, SPARC, secreted protein acidic and rich in cysteine, TfR, transferrin receptor, CTL, cytotoxic T lymphocytes, ODN, oligodeoxynucleotides, nMOFs, nanoscale metal-organic frameworks, ROS, reactive oxygen species, AuNPs, gold nanoparticles, medicine, EPG, egg phosphatidylglycerol, CAR-T, Chimeric antigen receptor-modified T-cell therapy, Chemotherapy, business.industry, AC-NPs, antigen-capturing nanoparticles, TIE2, tyrosine kinase with immunoglobulin and epidermal growth factor homology domain 2, 020601 biomedical engineering, EGFR, epidermal growth factor receptor, LMWH, low molecular weight heparin, PTX, paclitaxel, lcsh:Biology (General), Cancer research, MnO2, manganese dioxide, NK, nature killer, sense organs, business, RBC, red-blood-cell
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المؤلفون: Yi Guo, Mingshi Yang, Li Zhang, Changzhi Shi, Dongmei Cun, Hriday Bera
المصدر: Acta Pharmaceutica Sinica. B
Guo, Y, Bera, H, Shi, C, Zhang, L, Cun, D & Yang, M 2021, ' Pharmaceutical strategies to extend pulmonary exposure of inhaled medicines ', Acta Pharmaceutica Sinica B, vol. 11, no. 8, pp. 2565-2584 . https://doi.org/10.1016/j.apsb.2021.05.015
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2565-2584 (2021)مصطلحات موضوعية: PLA, polylactic acid, MPP, mucus-penetrating particles, PLGA, poly(lactic-co-glycolic acid), Review, CS, chitosan, Pulmonary exposure, MW, molecular weight, PVA, polyvinyl alcohol, 0302 clinical medicine, Inhaled sustained release formulations, BALF, bronchoalveolar lavage fluid, General Pharmacology, Toxicology and Pharmaceutics, Patient compliance, COPD, chronic obstructive pulmonary diseases, HA, hyaluronic acid, DPIs, dry powder inhalers, 0303 health sciences, DPPC, dipalmitoylphosphatidylcholine, FDA, US food and drug administration, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Obstructive Pulmonary Diseases, API, active pharmaceutical ingredient, NLCs, nanostructured lipid carriers, Clearance, medicine.medical_specialty, LABA, long-acting β2-adrenoceptor agonist, RM1-950, IL-5, interleukin-5, PCL, poly-ε-caprolactone, 03 medical and health sciences, LPPs, large porous particles, medicine, FDKP, fumaryl diketopiperazine, Intensive care medicine, Pharmaceutical strategies, Systemic diseases, Da, aerodynamic diameters, 030304 developmental biology, Asthma, PEG, polyethylene glycol, Lung, PVA - Polyvinyl alcohol, business.industry, DSPC, 1,2-distearoyl-sn-glycero-3-phosphocholine, Therapeutic effect, Drug administration, Pulmonary clearance pathways, MP, mucoadhesive particles, medicine.disease, Pulmonary drug delivery, SLNs, solid lipid nanoparticles, PDD, pulmonary drug delivery, Tmax, time of maximum concentration, ALIS, amikacin liposomal inhalation suspension, Mn, number-average molecular weight, MDIs, metered dose inhalers, Pulmonary safety, IL-4, interleukin-4, MCE, mucociliary escalator, PK, pharmacokinetics, Therapeutics. Pharmacology, ELF, epithelial lining fluid, business, Local lung diseases
وصف الملف: application/pdf
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المؤلفون: Liangju Kuang, Zhihao Jia, Kun Ho Kim, Meng Deng, Gabrielle Shafer, Paul Lengemann, Naagarajan Narayanan, Victor Bernal-Crespo, Shihuan Kuang
المصدر: Bioactive Materials, Vol 6, Iss 4, Pp 1201-1213 (2021)
Bioactive Materialsمصطلحات موضوعية: Myoblast proliferation, MHC, Myosin heavy chain, AChR, Acetyl choline receptors, Chondroitin sulfate, VML, Volumetric muscle loss, Hyaluronic acid, 0206 medical engineering, Biomedical Engineering, 02 engineering and technology, MyoD, Article, EDC, 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide, Biomaterials, Myoblasts, chemistry.chemical_compound, ECM, Extracellular matrix, medicine, lcsh:TA401-492, Myocyte, PEGDA, Poly(ethylene glycol) diacrylate, Volumetric muscle loss, lcsh:QH301-705.5, CS, Chondroitin Sulfate, Regeneration (biology), GAG, Glycosaminoglycan, Skeletal muscle, Hydrogels, eMHC, embryonic myosin heavy chain, 021001 nanoscience & nanotechnology, NHS, N-hydroxysuccinimide, 020601 biomedical engineering, HA, Hyaluronic acid, MES, 2-(N-morpholino) ethanesulfonic acid, Cell biology, medicine.anatomical_structure, chemistry, lcsh:Biology (General), Skeletal muscle tissue engineering, Self-healing hydrogels, lcsh:Materials of engineering and construction. Mechanics of materials, 0210 nano-technology, C2C12, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf482001b2545446cea5faca61842be
http://www.sciencedirect.com/science/article/pii/S2452199X20302632 -
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المؤلفون: Yuehong Xu, Sisi Cao, Kaiyue Yu, Yuanhao Zhai, Xiaoyuan Yang, Chuanbin Wu, Fengdie Yang, Yi Lu, Yixuan Wang, Xiuming Yu
المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 505-519 (2021)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: PsA, psoriatic arthritis, Arthritis, PVP, polyvinyl pyrrolidone, 0302 clinical medicine, TEWL, transepidermal water loss, Blank-MN, blank layered MNs, General Pharmacology, Toxicology and Pharmaceutics, NSAIDs, nonsteroidal anti-inflammatory drugs, HA, hyaluronic acid, SC, stratum corneum, TNF-α, tumor necrosis factor α, 0303 health sciences, OCT, optical coherence tomography, Diclofenac Sodium, IMQ, imiquimod, Muscle atrophy, RhB, rhodamine B, 030220 oncology & carcinogenesis, Psoriatic arthritis, PDMS, polydimethylsiloxane, Original Article, medicine.symptom, NIC, nicotinamide, medicine.drug, Diclofenac sodium, medicine.medical_specialty, IVISR, in vivo imaging system, SEM, scanning electron microscope, CLSM, confocal laser scanning microscope, Urology, Tacrolimus, TAC-MN, layered MNs loading TAC in the inter-layer of needles, 03 medical and health sciences, Diclofenac, Psoriasis Area and Severity Index, Psoriasis, medicine, DIC-MN, layered MNs loading DIC in the tip-layer of needles, 030304 developmental biology, C6, coumarin 6, business.industry, DIC, diclofenac sodium, MIX-MN, unlayered MNs loading the mixture of DIC and TAC in needles, lcsh:RM1-950, Layered microneedles, medicine.disease, IL-17A, interleukin 17A, PASI, psoriasis area and severity index, lcsh:Therapeutics. Pharmacology, TD-MN, layered MNs co-loading TAC in the inter-layer of needles and DIC in the tip-layer, Need-based drug delivery, MN, microneedle, TAC, tacrolimus, business
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المؤلفون: Tanja Dominko, Pamela J. Weathers, David Dolivo
المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 322-339 (2021)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: BUN, blood urea nitrogen, Artesunate, Review, Pharmacology, Col I, type I collagen, LAP, latency-associated peptide, chemistry.chemical_compound, 0302 clinical medicine, Scar, HUVEC, human umbilical vein endothelial cell, Fibrosis, CCl4, carbon tetrachloride, NAG, N-acetyl-β-d-glucosaminidase, General Pharmacology, Toxicology and Pharmaceutics, Artemisinin, HA, hyaluronic acid, 0303 health sciences, LDH, lactate dehydrogenase, LDH - Lactate dehydrogenase, mTOR, mechanistic target of rapamycin, TGF, β-transforming growth factor-β, DLA, dried leaf Artemisia, i.p., intraperitoneal, HSC, hepatic stellate cell, ALP - Alkaline phosphatase, DHA, dihydroartemisinin, ECM, extracellular matrix, MMP, matrix metalloproteinase, Alt alanine aminotransferase, 030220 oncology & carcinogenesis, MI, myocardial infarction, Fibroblast, TIMP, tissue inhibitor of metalloproteinase, medicine.drug, TGF-β, Anti fibrotic, ASP, aspartate aminotransferase, PCNA, proliferating cell nuclear antigen, BDL, bile duct ligation, FLS, fibroblast-like synoviocyte, STZ, streptozotocin, PHN, passive heymann nephritis, CTGF, connective tissue growth factor, 03 medical and health sciences, ROS, reactive oxygen species, ALT, alanine aminotransferase, parasitic diseases, medicine, BAD, BCL-2-associated agonist of cell death, sCr, serum creatinine, NICD, Notch intracellular domain, UUO, unilateral ureteral obstruction, 030304 developmental biology, Myofibroblast, ALP, alkaline phosphatase, business.industry, lcsh:RM1-950, medicine.disease, AMPK, AMP-activated protein kinase, lcsh:Therapeutics. Pharmacology, Artemisia, chemistry, Tissue fibrosis, BSA, bovine serum albumin, α-SMA, smooth muscle α-actin, business, EMT, epithelial-to-mesenchymal transition, MAPK, mitogen-activated protein kinase
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