المؤلفون: Gao Z; General Medical Department, Heilongjiang Provincial Hospital, Harbin, Heilongjiang, China., Lv J; Department of Pediatric Dentistry, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China., Tong TT; Department of General Surgery, The Fourth Affiliated Hospital of Harbin Medical University, and Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, Heilongjiang, China., Zhang K; Department of General Surgery, The Fourth Affiliated Hospital of Harbin Medical University, and Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, Heilongjiang, China., Han YX; Department of General Surgery, The Fourth Affiliated Hospital of Harbin Medical University, and Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, Heilongjiang, China., Zhao Y; Department of General Surgery, The Fourth Affiliated Hospital of Harbin Medical University, and Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, Heilongjiang, China., Shen MM; Department of General Surgery, The Fourth Affiliated Hospital of Harbin Medical University, and Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, Heilongjiang, China., Liu Y; Department of General Surgery, The Fourth Affiliated Hospital of Harbin Medical University, and Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, Heilongjiang, China., Ban T; Department of General Surgery, The Fourth Affiliated Hospital of Harbin Medical University, and Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, Heilongjiang, China.; Heilongjiang Academy of Medical Sciences, Harbin, Heilongjiang, China., Sun Y; Harbin Medical University Science Park, Harbin Medical University, Harbin, Heilongjiang, China.

المصدر: PeerJ [PeerJ] 2024 Jun 04; Vol. 12, pp. e17559. Date of Electronic Publication: 2024 Jun 04 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: PeerJ Inc Country of Publication: United States NLM ID: 101603425 Publication Model: eCollection Cited Medium: Internet ISSN: 2167-8359 (Electronic) Linking ISSN: 21678359 NLM ISO Abbreviation: PeerJ Subsets: MEDLINE

مواضيع طبية MeSH: TRPM Cation Channels*/metabolism , TRPM Cation Channels*/antagonists & inhibitors , TRPM Cation Channels*/genetics , Arsenic Trioxide*/pharmacology , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/drug therapy , Colorectal Neoplasms*/metabolism , Cell Movement*/drug effects , Apoptosis*/drug effects , Cell Proliferation*/drug effects , Cell Survival*/drug effects, Humans ; HCT116 Cells ; Oxides/pharmacology ; Antineoplastic Agents/pharmacology ; Neoplasm Invasiveness ; Arsenicals/pharmacology

المؤلفون: Shen J; Department of Gastroenterology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, Jiangsu, China., Qian N; Beijing Immunoah Pharma Tech Co., Ltd., Beijing 100141, China., Xu G; Beijing Immunoah Pharma Tech Co., Ltd., Beijing 100141, China., Dou X; Beijing Immunoah Pharma Tech Co., Ltd., Beijing 100141, China., An Y; Department of Preventive Treatment of Disease, Chengde Traditional Medicine Hospital, Hebei 067000, China., Yang C; Beijing Immunoah Pharma Tech Co., Ltd., Beijing 100141, China., Liu Y; Beijing Immunoah Pharma Tech Co., Ltd., Beijing 100141, China., Liu Y; Beijing Immunoah Pharma Tech Co., Ltd., Beijing 100141, China., Pan X; Beijing Immunoah Pharma Tech Co., Ltd., Beijing 100141, China., Wang J; Beijing Immunoah Pharma Tech Co., Ltd., Beijing 100141, China., Bai G; Beijing Immunoah Pharma Tech Co., Ltd., Beijing 100141, China., Chen H; Department of Gastroenterology, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China., Zhu X; Department of Gastroenterology, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China., Gao X; Beijing Immunoah Pharma Tech Co., Ltd., Beijing 100141, China., Zhou G; Department of Gastroenterology, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China. Electronic address: zhougx@ntu.edu.cn., Xu Q; Beijing Immunoah Pharma Tech Co., Ltd., Beijing 100141, China. Electronic address: xuqinzhi@immunoah.cn.

المصدر: International immunopharmacology [Int Immunopharmacol] 2024 Aug 20; Vol. 137, pp. 112424. Date of Electronic Publication: 2024 Jun 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Colorectal Neoplasms*/drug therapy , Colorectal Neoplasms*/immunology , Colorectal Neoplasms*/therapy , Epithelial Cell Adhesion Molecule*/metabolism , CD3 Complex*/immunology, Animals ; Humans ; Mice ; Tumor Necrosis Factor Receptor Superfamily, Member 9/metabolism ; HCT116 Cells ; Xenograft Model Antitumor Assays ; Antineoplastic Agents, Immunological/pharmacology ; Antineoplastic Agents, Immunological/therapeutic use ; Female ; Cell Line, Tumor ; Antibodies, Monoclonal/pharmacology ; Antibodies, Monoclonal/therapeutic use ; Mice, Inbred BALB C ; T-Lymphocytes/immunology ; T-Lymphocytes/drug effects ; Antibodies, Bispecific/pharmacology ; Antibodies, Bispecific/therapeutic use ; Immunotherapy/methods

المؤلفون: Fierro-Arenas A; Innate Immunity Laboratory, Immunology Program, Faculty of Medicine, Universidad de Chile, Santiago, Chile; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Landskron G; Center of Biomedical Research (CIBMED), School of Medicine, Faculty of Medicine-Clínica Las Condes, Universidad Finis Terrae, Santiago, Chile., Camhi-Vainroj I; Innate Immunity Laboratory, Immunology Program, Faculty of Medicine, Universidad de Chile, Santiago, Chile., Basterrechea B; Innate Immunity Laboratory, Immunology Program, Faculty of Medicine, Universidad de Chile, Santiago, Chile., Parada-Venegas D; Innate Immunity Laboratory, Immunology Program, Faculty of Medicine, Universidad de Chile, Santiago, Chile; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Lobos-González L; Regenerative Medicine Center, Faculty of Medicine, Clínica Alemana-Universidad del Desarrollo, Santiago, Chile; Advanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences, Universidad de Chile, Santiago, Chile., Dubois-Camacho K; Innate Immunity Laboratory, Immunology Program, Faculty of Medicine, Universidad de Chile, Santiago, Chile; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Araneda C; Innate Immunity Laboratory, Immunology Program, Faculty of Medicine, Universidad de Chile, Santiago, Chile; Center of Biomedical Research (CIBMED), School of Medicine, Faculty of Medicine-Clínica Las Condes, Universidad Finis Terrae, Santiago, Chile., Romero C; Center of Biomedical Research (CIBMED), School of Medicine, Faculty of Medicine-Clínica Las Condes, Universidad Finis Terrae, Santiago, Chile., Domínguez A; Center of Biomedical Research (CIBMED), School of Medicine, Faculty of Medicine-Clínica Las Condes, Universidad Finis Terrae, Santiago, Chile., Vásquez G; Innate Immunity Laboratory, Immunology Program, Faculty of Medicine, Universidad de Chile, Santiago, Chile; Center of Biomedical Research (CIBMED), School of Medicine, Faculty of Medicine-Clínica Las Condes, Universidad Finis Terrae, Santiago, Chile., López-K F; Cancer Center, Clínica Universidad de los Andes, Santiago, Chile., Alvarez K; Cancer Center, Clínica Universidad de los Andes, Santiago, Chile., González CM; School of Veterinary Medicine, Faculty of Life Sciences, Universidad Andrés Bello, Santiago, Chile., Hager Ribeiro C; Immunology Program, Faculty of Medicine, Universidad de Chile, Santiago, Chile., Balboa E; Center of Biomedical Research (CIBMED), School of Medicine, Faculty of Medicine-Clínica Las Condes, Universidad Finis Terrae, Santiago, Chile., Eugenin E; Department of Neuroscience, Cell Biology and Anatomy, University of Texas Medical Branch (UTMB), Galveston, USA., Hermoso MA; Innate Immunity Laboratory, Immunology Program, Faculty of Medicine, Universidad de Chile, Santiago, Chile; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., De la Fuente López M; Center of Biomedical Research (CIBMED), School of Medicine, Faculty of Medicine-Clínica Las Condes, Universidad Finis Terrae, Santiago, Chile. Electronic address: mdelafuente@uft.cl.

المصدر: Life sciences [Life Sci] 2024 Aug 15; Vol. 351, pp. 122851. Date of Electronic Publication: 2024 Jun 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE

مواضيع طبية MeSH: Colonic Neoplasms*/pathology , Colonic Neoplasms*/metabolism , Colonic Neoplasms*/genetics , Connexins*/metabolism , Connexins*/genetics , Disease Progression* , Nerve Tissue Proteins*/metabolism , Nerve Tissue Proteins*/genetics, Animals ; Female ; Humans ; Male ; Mice ; Biomarkers, Tumor/metabolism ; Biomarkers, Tumor/genetics ; Cell Line, Tumor ; Cell Proliferation ; Cell Survival ; Gene Expression Regulation, Neoplastic ; HCT116 Cells ; Mice, Inbred BALB C ; Mice, Inbred NOD ; Mice, SCID ; Probenecid/pharmacology ; Xenograft Model Antitumor Assays

المؤلفون: Chen Z; Department of Laboratory Medicine, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, China., Chen J; Department of Laboratory Medicine, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, China., Lin D; Department of Laboratory Medicine, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, China.; Guangdong Engineering Technology Research Center of Microfluidic Chip Medical Diagnosis, Guangzhou 510180, China., Kang H; Department of Pathology, School of Medicine, Jinan University, Guangzhou 510632, China., Luo Y; Department of Laboratory Medicine, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, China., Wang X; Department of Laboratory Medicine, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, China., Wang L; Department of Pathology, School of Medicine, Jinan University, Guangzhou 510632, China., Liu D; Department of Laboratory Medicine, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, China.; Guangdong Engineering Technology Research Center of Microfluidic Chip Medical Diagnosis, Guangzhou 510180, China.

المصدر: ACS biomaterials science & engineering [ACS Biomater Sci Eng] 2024 Aug 12; Vol. 10 (8), pp. 5265-5273. Date of Electronic Publication: 2024 Aug 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101654670 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-9878 (Electronic) Linking ISSN: 23739878 NLM ISO Abbreviation: ACS Biomater Sci Eng Subsets: MEDLINE

مواضيع طبية MeSH: Colonic Neoplasms*/pathology , Organoids*/pathology , Organoids*/metabolism , Neoplastic Stem Cells*/pathology , Neoplastic Stem Cells*/metabolism , Single-Cell Analysis*/methods, Humans ; Lab-On-A-Chip Devices ; High-Throughput Screening Assays/methods ; High-Throughput Screening Assays/instrumentation ; Cell Line, Tumor ; Cell Culture Techniques/methods ; Cell Culture Techniques/instrumentation ; HCT116 Cells ; Polyethylene Glycols/chemistry ; Polyethylene Glycols/pharmacology

المؤلفون: Cheong HH; Department of Computer and Information Science, Faculty of Science and Technology, University of Macau, Avenida de Universidade, Taipa, Macau SAR 999078, China., Zuo W; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Avenida de Universidade, Taipa, Macau SAR 999078, China.; Cancer Centre, Faculty of Health Sciences, University of  Macau, Avenida de Universidade, Taipa, Macau SAR 999078, China., Chen J; Department of Computer and Information Science, Faculty of Science and Technology, University of Macau, Avenida de Universidade, Taipa, Macau SAR 999078, China., Un CW; Department of Computer and Information Science, Faculty of Science and Technology, University of Macau, Avenida de Universidade, Taipa, Macau SAR 999078, China., Si YW; Department of Computer and Information Science, Faculty of Science and Technology, University of Macau, Avenida de Universidade, Taipa, Macau SAR 999078, China., Wong KH; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Avenida de Universidade, Taipa, Macau SAR 999078, China.; MoE Frontiers Science Center for Precision Oncology, University of Macau, Avenida de Universidade, Taipa, Macau SAR 999078, China.; Cancer Centre, Faculty of Health Sciences, University of  Macau, Avenida de Universidade, Taipa, Macau SAR 999078, China., Kwok HF; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Avenida de Universidade, Taipa, Macau SAR 999078, China.; MoE Frontiers Science Center for Precision Oncology, University of Macau, Avenida de Universidade, Taipa, Macau SAR 999078, China.; Cancer Centre, Faculty of Health Sciences, University of  Macau, Avenida de Universidade, Taipa, Macau SAR 999078, China., Siu SWI; Centre for Artificial Intelligence Driven Drug Discovery, Faculty of Applied Sciences, Macao Polytechnic University, R. de Luís Gonzaga Gomes, Macau SAR 999078, China.; Institute of Science and Environment, University of Saint Joseph, Estrada Marginal da Ilha Verde 14-17, Macau SAR 999078, China.

المصدر: Journal of chemical information and modeling [J Chem Inf Model] 2024 Aug 12; Vol. 64 (15), pp. 6174-6189. Date of Electronic Publication: 2024 Jul 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

مواضيع طبية MeSH: Candida albicans*/drug effects , Candida albicans*/genetics , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Peptides*/chemistry , Peptides*/pharmacology, Animals ; Humans ; Mice, Nude ; Genome, Fungal ; Computer Simulation ; Mice ; HCT116 Cells ; Xenograft Model Antitumor Assays

المؤلفون: Mohan N; Center for Epigenetics & Disease Prevention, Texas A&M Health, Houston, TX, USA., Johnson GS; Center for Epigenetics & Disease Prevention, Texas A&M Health, Houston, TX, USA.; CRISPR Therapeutics, South Boston, MA, USA., Tovar Perez JE; Center for Epigenetics & Disease Prevention, Texas A&M Health, Houston, TX, USA., Dashwood WM; Center for Epigenetics & Disease Prevention, Texas A&M Health, Houston, TX, USA., Rajendran P; Center for Epigenetics & Disease Prevention, Texas A&M Health, Houston, TX, USA. prajendran@tamu.edu.; Department of Translational Medical Sciences, Texas A&M College of Medicine, Houston, TX, USA. prajendran@tamu.edu., Dashwood RH; Center for Epigenetics & Disease Prevention, Texas A&M Health, Houston, TX, USA. rdashwood@tamu.edu.; Department of Translational Medical Sciences, Texas A&M College of Medicine, Houston, TX, USA. rdashwood@tamu.edu.

المصدر: Cell death & disease [Cell Death Dis] 2024 Aug 07; Vol. 15 (8), pp. 570. Date of Electronic Publication: 2024 Aug 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage* , Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/drug therapy , Colorectal Neoplasms*/metabolism , Alternative Splicing*/genetics , Alternative Splicing*/drug effects , Mice, Nude*, Humans ; Animals ; Mice ; Cell Line, Tumor ; Apoptosis/drug effects ; Apoptosis/genetics ; Gene Expression Regulation, Neoplastic/drug effects ; Wnt Signaling Pathway/drug effects ; DNA Repair/drug effects ; Drug Resistance, Neoplasm/genetics ; Drug Resistance, Neoplasm/drug effects ; Transcription Factors/metabolism ; Transcription Factors/genetics ; HCT116 Cells

المؤلفون: Yaghoubi N; Faculty of Pharmacy and Pharmaceutical Sciences, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran., Gholamzad A; Farhikhtegan Medical Convergence Sciences Research Center, Farhikhtegan Hospital Tehran Medical Sciences, Islamic Azad University, Tehran, Iran., Naji T; Department of Basic Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran., Gholamzad M; Department of Microbiology and Immunology, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran. Mgholamzad@iautmu.ac.ir.

المصدر: BMC biotechnology [BMC Biotechnol] 2024 Aug 02; Vol. 24 (1), pp. 52. Date of Electronic Publication: 2024 Aug 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101088663 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6750 (Electronic) Linking ISSN: 14726750 NLM ISO Abbreviation: BMC Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: Hesperidin*/chemistry , Hesperidin*/pharmacology , Hesperidin*/administration & dosage , Polylactic Acid-Polyglycolic Acid Copolymer*/chemistry , Colorectal Neoplasms*/drug therapy , Nanoparticles*/chemistry, Humans ; HCT116 Cells ; Cell Survival/drug effects ; Lactic Acid/chemistry ; Polyglycolic Acid/chemistry ; Drug Delivery Systems ; Particle Size ; Drug Carriers/chemistry ; Spectroscopy, Fourier Transform Infrared ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Nanoparticle Drug Delivery System/chemistry

المؤلفون: Chen H; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing 210009, People's Republic of China., Yang F; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing 210009, People's Republic of China., Zhao Q; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing 210009, People's Republic of China., Wang H; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing 210009, People's Republic of China., Zhu M; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing 210009, People's Republic of China., Li H; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing 210009, People's Republic of China., Ge Z; Department of Hematology, Zhongda Hospital, School of Medicine, Southeast University, Institute of Hematology Southeast University, Nanjing 210009, People's Republic of China., Zhang S; Department of General Thoractic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing 210009, People's Republic of China., Guo Q; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing 210009, People's Republic of China., Hui H; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, Nanjing 210009, People's Republic of China.

المصدر: The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2024 Aug 02; Vol. 76 (8), pp. 1006-1017.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0376363 Publication Model: Print Cited Medium: Internet ISSN: 2042-7158 (Electronic) Linking ISSN: 00223573 NLM ISO Abbreviation: J Pharm Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Oxaliplatin*/pharmacology , Cell Cycle Proteins*/metabolism , Colorectal Neoplasms*/drug therapy , Colorectal Neoplasms*/metabolism , Colorectal Neoplasms*/pathology , Protein-Tyrosine Kinases*/metabolism , Protein-Tyrosine Kinases*/antagonists & inhibitors , Drug Synergism* , HSP90 Heat-Shock Proteins*/metabolism , HSP90 Heat-Shock Proteins*/antagonists & inhibitors , Mice, Nude*, Humans ; Animals ; HCT116 Cells ; Xenograft Model Antitumor Assays ; Mice ; Mice, Inbred BALB C ; Cell Line, Tumor ; DNA Damage/drug effects ; Antineoplastic Agents/pharmacology ; Cell Cycle Checkpoints/drug effects ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Pyrimidinones/pharmacology ; Pyrimidines/pharmacology ; Pyrazoles/pharmacology

المؤلفون: Gao Y; Department of Histology and Embryology, Shantou University Medical College, Shantou 515041, China., Wen P; School of Medical Information and Engineering, Xuzhou Medical University, Xuzhou 221002, China., Shao C; Department of Histology and Embryology, Shantou University Medical College, Shantou 515041, China., Ye C; Department of Histology and Embryology, Shantou University Medical College, Shantou 515041, China., Chen Y; Department of Histology and Embryology, Shantou University Medical College, Shantou 515041, China., You J; Department of Histology and Embryology, Shantou University Medical College, Shantou 515041, China., Su Z; Department of Histology and Embryology, Shantou University Medical College, Shantou 515041, China.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 01; Vol. 25 (15). Date of Electronic Publication: 2024 Aug 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage* , Replication Protein A*/metabolism , Replication Protein A*/genetics , Radiation Tolerance*/drug effects , Radiation Tolerance*/genetics , Drug Resistance, Neoplasm*/genetics , Cdc20 Proteins*/metabolism , Cdc20 Proteins*/genetics, Humans ; Animals ; Mice ; Cell Line, Tumor ; Mice, Inbred BALB C ; Mice, Nude ; DNA Repair/drug effects ; Xenograft Model Antitumor Assays ; Cell Proliferation/drug effects ; Cisplatin/pharmacology ; HCT116 Cells ; Gene Expression Regulation, Neoplastic/drug effects

المؤلفون: Bakharzi M; Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.; Department of Interdisciplinary Oncology, Faculty of Medicine, University of British Columbia, Vancouver, Canada., Attar E; Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran., Garmabi H; Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran., Esmaeili AA; Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran., Bahrami AR; Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.; Industrial Biotechnology Research Group, Institute of Biotechnology, Ferdowsi University of Mashhad, Mashhad, Iran., Danehchin M; Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran., Matin MM; Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.; Novel Diagnostics and Therapeutics Research Group, Institute of Biotechnology, Ferdowsi University of Mashhad, Mashhad, Iran.

المصدر: Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2024 Aug; Vol. 38 (8), pp. e23779.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 9717231 Publication Model: Print Cited Medium: Internet ISSN: 1099-0461 (Electronic) Linking ISSN: 10956670 NLM ISO Abbreviation: J Biochem Mol Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Pyrimidines*/pharmacology , Pyrimidines*/chemistry , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Apoptosis*/drug effects , Colonic Neoplasms*/drug therapy , Colonic Neoplasms*/pathology, Animals ; Mice ; Humans ; Molecular Docking Simulation ; Benzothiazoles/chemistry ; Benzothiazoles/pharmacology ; HCT116 Cells ; NIH 3T3 Cells ; Mice, Inbred BALB C ; Cell Line, Tumor