المؤلفون: Bi G; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hong Kong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China., Liang F; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hong Kong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China., Wu T; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hong Kong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China., Wang P; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hong Kong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China., Jiang X; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hong Kong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China., Hu S; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hong Kong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China., Wu C; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hong Kong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China., Zhou W; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hong Kong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China., Guo J; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hong Kong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China., Yang X; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hong Kong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China., Fang JH; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hong Kong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China., Chen W; Department of Pharmacy, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China., Bi H; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hong Kong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.; The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, China.

المصدر: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2024 Aug; Vol. 135 (2), pp. 148-163. Date of Electronic Publication: 2024 Jun 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843 (Electronic) Linking ISSN: 17427835 NLM ISO Abbreviation: Basic Clin Pharmacol Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Pregnane X Receptor*/metabolism , Pregnane X Receptor*/genetics , Liver Regeneration*/drug effects , Cytochrome P-450 CYP3A*/metabolism , Pregnenolone Carbonitrile*/pharmacology , Liver*/metabolism , Liver*/enzymology , Liver*/drug effects , Hepatomegaly*/metabolism , Hepatomegaly*/pathology, Animals ; Male ; Rats ; Aryl Hydrocarbon Hydroxylases/metabolism ; Aryl Hydrocarbon Hydroxylases/genetics ; Cytochrome P450 Family 2/metabolism ; Cytochrome P450 Family 2/genetics ; Rats, Sprague-Dawley ; Cytochrome P-450 CYP1A2/metabolism ; Cytochrome P-450 CYP1A2/genetics ; Steroid 16-alpha-Hydroxylase/metabolism ; Steroid 16-alpha-Hydroxylase/genetics ; Steroid 12-alpha-Hydroxylase/metabolism ; Steroid 12-alpha-Hydroxylase/genetics ; Hepatectomy

المؤلفون: Schueller SS; Child and Adolescent Health Service, Perth, WA, Australia tobiasstrunk@yahoo.de., Strunk T; Child and Adolescent Health Service, Perth, WA, Australia tobiasstrunk@yahoo.de.

المصدر: The New England journal of medicine [N Engl J Med] 2024 Jul 25; Vol. 391 (4), pp. 356.

نوع المنشور: Case Reports; Journal Article

بيانات الدورية: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE

مواضيع طبية MeSH: Pregnancy Complications, Infectious*/diagnosis , Pregnancy Complications, Infectious*/drug therapy , Syphilis, Congenital*/complications , Syphilis, Congenital*/diagnosis , Syphilis, Congenital*/drug therapy , Hepatomegaly*/diagnostic imaging , Hepatomegaly*/etiology, Female ; Humans ; Infant, Newborn ; Male ; Pregnancy ; Anti-Bacterial Agents/therapeutic use ; Syphilis Serodiagnosis ; Treponema pallidum/isolation & purification

المؤلفون: Rossignol J; CEREMAST, Imagine Institute, INSERM U1163, AP-HP, Necker Children's Hospital, Paris Centre University, Paris, France., Canioni D; CEREMAST, Department of Pathology, Necker Children's Hospital, AP-HP, Paris Centre University, Paris, France., Aouba A; Department of Internal Medicine, Normandy University School of Medicine, Caen, France., Bulai-Livideanu C; CEREMAST, Department of Dermatology, Hôpital Larrey, CHU Toulouse, Toulouse, France., Barete S; CEREMAST, Dermatology Department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France., Lancesseur C; CEREMAST, Hematology Institute, Normandy University School of Medicine, Caen, France., Polivka L; CEREMAST, Imagine Institute, INSERM U1163, AP-HP, Necker Children's Hospital, Paris Centre University, Paris, France., Madrange M; CEREMAST, Imagine Institute, INSERM U1163, AP-HP, Necker Children's Hospital, Paris Centre University, Paris, France., Ballul T; CEREMAST, Imagine Institute, INSERM U1163, AP-HP, Necker Children's Hospital, Paris Centre University, Paris, France., Neuraz A; Department of Bioinformatics, Necker Children's Hospital, AP-HP, Paris Centre University, Imagine Institute, INSERM U1163, Paris, France., Greco C; CEREMAST, Imagine Institute, INSERM U1163, AP-HP, Necker Children's Hospital, Paris Centre University, Paris, France., Agopian J; Centre de Recherche en Cancérologie de Marseille, INSERM U1068, Marseille, France.; Association Française pour les Initiatives de Recherche sur le Mastocyte et les Mastocytoses (AFIRMM), Marseille, France., Brenet F; Centre de Recherche en Cancérologie de Marseille, INSERM U1068, Marseille, France.; Association Française pour les Initiatives de Recherche sur le Mastocyte et les Mastocytoses (AFIRMM), Marseille, France., Dubreuil P; Centre de Recherche en Cancérologie de Marseille, INSERM U1068, Marseille, France.; Association Française pour les Initiatives de Recherche sur le Mastocyte et les Mastocytoses (AFIRMM), Marseille, France., Lemal R; Histocompatibility Laboratory, EA 7453-Université Clermont Auvergne, CHU de Clermont-Ferrand, Clermont-Ferrand, France., Tournilhac O; CEREMAST, Adult Clinical Hematology, CHU Clermont-Ferrand, INSERM CIC501, EA 7453 - Clermont Auvergne University, Clermont-Ferrand, France., Terriou L; CEREMAST, Department of Internal Medicine and Clinical Immunology, CHU Lille, Lille, France., Launay D; CEREMAST, Department of Internal Medicine and Clinical Immunology, CHU Lille, Lille, France.; Lille University, INSERM U1286 INFINITE, CHU Lille, Lille, France., Bouillet L; CEREMAST, Clinical Immunology/Internal Medicine Department, National Reference Center for Angioedema, Grenoble University Hospital, Grenoble, France., Gourguechon C; Department of Hematology, Amiens University Hospital, Amiens, France., Frenzel L; CEREMAST, Imagine Institute, INSERM U1163, AP-HP, Necker Children's Hospital, Paris Centre University, Paris, France., Meni C; CEREMAST, Imagine Institute, INSERM U1163, AP-HP, Necker Children's Hospital, Paris Centre University, Paris, France., Gaudy-Marqueste C; CEREMAST, Department of Dermatology, Aix-Marseille University, CHU Timone, Marseille, France., Gousseff M; Department of Internal Medicine, Centre Hospitalier Bretagne Atlantique, Vannes, France., Le Mouel E; CEREMAST, Department of Internal Medicine and Clinical Immunology, Rennes University Hospital, Rennes, France., Hamidou M; CEREMAST, Department of Internal Medicine, Hôtel-Dieu University Hospital, Nantes, France., Neel A; CEREMAST, Department of Internal Medicine, Hôtel-Dieu University Hospital, Nantes, France., Ranta D; Department of Hematology, Nancy University Hospital, Nancy, France., Jaussaud R; Department of Internal Medicine and Clinical Immunology, Nancy University Hospital, Vandoeuvre-lès-Nancy, France., Guilpain P; CEREMAST, Department of Internal Medicine-Multi-organ Diseases, Saint-Eloi University Hospital, Montpellier University, Montpellier, France., Molina TJ; CEREMAST, Department of Pathology, Necker Children's Hospital, AP-HP, Paris Centre University, Paris, France., Bruneau J; CEREMAST, Department of Pathology, Necker Children's Hospital, AP-HP, Paris Centre University, Paris, France., Lhermitte L; CEREMAST, Laboratory of Onco-Hematology, Necker Children's Hospital, APHP, Paris, France., Garcelon N; Paris Centre University, Imagine Institute, Data Science Platform, INSERM UMR 1163, Paris, France., Javier RM; CEREMAST, Department of Rheumatology, Strasbourg University Hospital, Strasbourg, France., Pelletier F; CEREMAST, Department of Dermatology, Allergology Unit, University Hospital of Besançon, Besançon, France., Castelain F; CEREMAST, Department of Dermatology, Allergology Unit, University Hospital of Besançon, Besançon, France., Retornaz F; Unité de soins et de recherche en médecine interne et maladies infectieuses, European Hospital, Marseille, France., Cabrera Q; Department of Haematology, Sud Reunion University Hospital, Saint Pierre, La Réunion, France., Zunic P; Department of Haematology, Sud Reunion University Hospital, Saint Pierre, La Réunion, France., Gourin MP; CEREMAST, Department of Hematology, CHU Dupuytren, Limoges, France., Wierzbicka-Hainaut E; CEREMAST, Department of Dermatology, CHU de Poitiers, Poitiers, France., Viallard JF; Department of Internal Medicine and Infectious Diseases, Haut-Lévêque Hospital, CHRU Bordeaux, Bordeaux University, Bordeaux, France., Lavigne C; CEREMAST, Department of Internal Medicine and Clinical Immunology, University Hospital, Angers, France., Hoarau C; CEREMAST, Service d'Immunologie Clinique et d'Allergologie, Centre Hospitalier Régional Universitaire, Tours, France., Durieu I; CEREMAST, Department of Internal Medicine, Adult Cystic Fibrosis Care Center, Hospices Civils de Lyon, Lyon, France., Heiblig M; CEREMAST, Department of Hematology, Lyon-Sud Hospital, Hospices Civils de Lyon, Pierre-Bénite, France., Dimicoli-Salazar S; Department of Hematology, CHU de Bordeaux, Bordeaux, France., Torregrosa-Diaz JM; Department of Hematology, CHU de Poitiers, Poitiers, France., Soria A; CEREMAST, Department of Dermatology and Allergy, Tenon Hospital, Sorbonne University, Paris, France., Arock M; CEREMAST, Laboratory of Hematology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France., Lortholary O; CEREMAST, Imagine Institute, INSERM U1163, AP-HP, Necker Children's Hospital, Paris Centre University, Paris, France.; Infectious and Tropical Diseases Department, Necker-Pasteur Infectiology Center, AP-HP, Necker Children's Hospital, Paris Centre University, Paris, France., Bodemer C; CEREMAST, Imagine Institute, INSERM U1163, AP-HP, Necker Children's Hospital, Paris Centre University, Paris, France., Pol S; AP-HP.Centre Université Paris Centre, Groupe Hospitalier Cochin Port Royal, DMU Cancérologie et spécialités médico-chirurgicales, Service d'Hépatologie, Paris, France., Mallet V; AP-HP.Centre Université Paris Centre, Groupe Hospitalier Cochin Port Royal, DMU Cancérologie et spécialités médico-chirurgicales, Service d'Hépatologie, Paris, France., Hermine O; CEREMAST, Imagine Institute, INSERM U1163, AP-HP, Necker Children's Hospital, Paris Centre University, Paris, France., Damaj G; CEREMAST, Hematology Institute, Normandy University School of Medicine, Caen, France.

مؤلفون مشاركون: on behalf the CEREMAST Network

المصدر: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2024 Jul; Vol. 44 (7), pp. 1680-1688. Date of Electronic Publication: 2024 Mar 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101160857 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-3231 (Electronic) Linking ISSN: 14783223 NLM ISO Abbreviation: Liver Int Subsets: MEDLINE

مواضيع طبية MeSH: Mastocytosis, Systemic*/pathology , Mastocytosis, Systemic*/complications , Liver*/pathology , Hepatomegaly*/pathology , Hepatomegaly*/etiology, Humans ; Retrospective Studies ; Female ; Male ; Middle Aged ; Adult ; Biopsy ; Aged ; Hypertension, Portal/pathology ; Hypertension, Portal/etiology ; France ; Liver Cirrhosis/pathology ; Mast Cells/pathology ; Alkaline Phosphatase/blood ; Prognosis

المؤلفون: Zhang Y; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China., Yang J; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China., Fan S; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China., Gao Y; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China., Cai C; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China., Li H; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China., Li X; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China., Yang X; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China; The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen 518005, China., Xing Y; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China., Huang M; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China., Bi H; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China; The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen 518005, China. Electronic address: bihchang@smu.edu.cn.

المصدر: Toxicology letters [Toxicol Lett] 2024 Jun; Vol. 397, pp. 79-88. Date of Electronic Publication: 2024 May 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7709027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3169 (Electronic) Linking ISSN: 03784274 NLM ISO Abbreviation: Toxicol Lett Subsets: MEDLINE

مواضيع طبية MeSH: Cell Proliferation*/drug effects , Hepatocytes*/drug effects , Hepatocytes*/metabolism , Hepatocytes*/pathology , Hepatomegaly*/chemically induced , Hepatomegaly*/metabolism , Hepatomegaly*/pathology , Liver*/drug effects , Liver*/metabolism , Liver*/pathology , PPAR alpha*/agonists , PPAR alpha*/metabolism , Pregnane X Receptor*/metabolism , Pregnane X Receptor*/genetics , Pyrimidines*/pharmacology , YAP-Signaling Proteins*/metabolism, Animals ; Male ; Mice ; Adaptor Proteins, Signal Transducing/metabolism ; Aryl Hydrocarbon Hydroxylases ; beta Catenin/metabolism ; Cell Cycle Proteins/metabolism ; Cell Cycle Proteins/genetics ; Cytochrome P-450 CYP3A ; Cytochrome P-450 CYP4A/metabolism ; Cytochrome P-450 CYP4A/genetics ; Cytochrome P450 Family 2 ; Cytochrome P450 Family 4/genetics ; Cytochrome P450 Family 4/metabolism ; Ki-67 Antigen/metabolism ; Membrane Proteins ; Mice, Inbred C57BL ; Phosphoproteins/metabolism ; Phosphoproteins/genetics ; Signal Transduction/drug effects ; Steroid Hydroxylases

المؤلفون: Wu T; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism and Guangdong Provincial Key Laboratory of New Drug Screening and Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China (T.W., L.L., W.Z., G.B., X.J., M.G., X.Y., J.F., J.P., S.F., H.B.) and The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, China (X.Y., H.B.)., Li L; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism and Guangdong Provincial Key Laboratory of New Drug Screening and Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China (T.W., L.L., W.Z., G.B., X.J., M.G., X.Y., J.F., J.P., S.F., H.B.) and The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, China (X.Y., H.B.)., Zhou W; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism and Guangdong Provincial Key Laboratory of New Drug Screening and Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China (T.W., L.L., W.Z., G.B., X.J., M.G., X.Y., J.F., J.P., S.F., H.B.) and The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, China (X.Y., H.B.)., Bi G; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism and Guangdong Provincial Key Laboratory of New Drug Screening and Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China (T.W., L.L., W.Z., G.B., X.J., M.G., X.Y., J.F., J.P., S.F., H.B.) and The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, China (X.Y., H.B.)., Jiang X; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism and Guangdong Provincial Key Laboratory of New Drug Screening and Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China (T.W., L.L., W.Z., G.B., X.J., M.G., X.Y., J.F., J.P., S.F., H.B.) and The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, China (X.Y., H.B.)., Guo M; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism and Guangdong Provincial Key Laboratory of New Drug Screening and Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China (T.W., L.L., W.Z., G.B., X.J., M.G., X.Y., J.F., J.P., S.F., H.B.) and The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, China (X.Y., H.B.)., Yang X; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism and Guangdong Provincial Key Laboratory of New Drug Screening and Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China (T.W., L.L., W.Z., G.B., X.J., M.G., X.Y., J.F., J.P., S.F., H.B.) and The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, China (X.Y., H.B.)., Fang J; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism and Guangdong Provincial Key Laboratory of New Drug Screening and Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China (T.W., L.L., W.Z., G.B., X.J., M.G., X.Y., J.F., J.P., S.F., H.B.) and The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, China (X.Y., H.B.)., Pang J; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism and Guangdong Provincial Key Laboratory of New Drug Screening and Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China (T.W., L.L., W.Z., G.B., X.J., M.G., X.Y., J.F., J.P., S.F., H.B.) and The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, China (X.Y., H.B.)., Fan S; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism and Guangdong Provincial Key Laboratory of New Drug Screening and Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China (T.W., L.L., W.Z., G.B., X.J., M.G., X.Y., J.F., J.P., S.F., H.B.) and The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, China (X.Y., H.B.) bihchang@smu.edu.cn fanshch3@smu.edu.cn., Bi H; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism and Guangdong Provincial Key Laboratory of New Drug Screening and Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China (T.W., L.L., W.Z., G.B., X.J., M.G., X.Y., J.F., J.P., S.F., H.B.) and The State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen, China (X.Y., H.B.) bihchang@smu.edu.cn fanshch3@smu.edu.cn.

المصدر: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2024 Jun 17; Vol. 52 (7), pp. 597-605. Date of Electronic Publication: 2024 Jun 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: United States NLM ID: 9421550 Publication Model: Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE

مواضيع طبية MeSH: Hepatomegaly*/chemically induced , Hepatomegaly*/metabolism , Pregnane X Receptor*/agonists , Pregnane X Receptor*/metabolism , Gastrointestinal Microbiome*/drug effects , Pregnenolone Carbonitrile*/pharmacology , Mice, Inbred C57BL* , YAP-Signaling Proteins*/metabolism , Fecal Microbiota Transplantation*/methods, Animals ; Mice ; Male ; Liver/drug effects ; Liver/metabolism

المؤلفون: Vieira IF; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil., Waisberg DR; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil. Electronic address: daniel.waisberg@hc.fm.usp.br., Rocha-Santos V; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil., Pinheiro RS; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil., Martino RB; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil., Ducatti L; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil., Arantes RM; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil., Nacif LS; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil., Lee AD; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil., Haddad LB; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil; Laboratory of Medical Investigation 37 (LIM-37), Faculdade de Medicina da Universidade de São Paulo (FMUSP), Sao Paulo, Brazil., Song AT; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil., Marin-Castro P; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil., Alvarez J; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil., Silva MS; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil., Almeida JD; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil., Galvão FH; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil; Laboratory of Medical Investigation 37 (LIM-37), Faculdade de Medicina da Universidade de São Paulo (FMUSP), Sao Paulo, Brazil., Carneiro-D Albuquerque LA; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil; Laboratory of Medical Investigation 37 (LIM-37), Faculdade de Medicina da Universidade de São Paulo (FMUSP), Sao Paulo, Brazil., Andraus W; Liver and Abdominal Organs Transplantation Division, Department of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de São Paulo (HC-FMUSP), São Paulo, Brazil; Laboratory of Medical Investigation 37 (LIM-37), Faculdade de Medicina da Universidade de São Paulo (FMUSP), Sao Paulo, Brazil.

المصدر: Transplantation proceedings [Transplant Proc] 2024 Jun; Vol. 56 (5), pp. 1098-1103. Date of Electronic Publication: 2024 Jun 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 0243532 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2623 (Electronic) Linking ISSN: 00411345 NLM ISO Abbreviation: Transplant Proc Subsets: MEDLINE

مواضيع طبية MeSH: Liver Transplantation* , Hepatomegaly*/surgery , Hepatomegaly*/etiology , Cysts*/surgery , Liver Diseases*/surgery, Humans ; Retrospective Studies ; Male ; Female ; Adult ; Middle Aged ; Hemangioma/surgery ; Hepatectomy/methods ; Treatment Outcome ; Liver Neoplasms/surgery

SCR Disease Name: Polycystic liver disease

المؤلفون: Wakabayashi N; Translational Research Program, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Yagishita Y; Translational Research Program, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.; Division of Endocrinology, Columbia University, New York, NY 10032, USA., Joshi T; Translational Research Program, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Kensler TW; Translational Research Program, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 26; Vol. 25 (9). Date of Electronic Publication: 2024 Apr 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Kelch-Like ECH-Associated Protein 1*/metabolism , Kelch-Like ECH-Associated Protein 1*/genetics , Hypercholesterolemia*/genetics , Hypercholesterolemia*/metabolism , Hypercholesterolemia*/pathology , Liver*/metabolism , Liver*/pathology , Hepatomegaly*/genetics , Hepatomegaly*/metabolism , Hepatomegaly*/pathology , Immunoglobulin J Recombination Signal Sequence-Binding Protein*/genetics , Immunoglobulin J Recombination Signal Sequence-Binding Protein*/metabolism, Animals ; Mice ; NF-E2-Related Factor 2/metabolism ; NF-E2-Related Factor 2/genetics ; Lipid Metabolism/genetics ; Gene Deletion ; Signal Transduction ; Cholesterol/metabolism ; Mice, Knockout ; Male ; Bile Acids and Salts/metabolism

المؤلفون: Prithvi A; Department of Paediatrics, St John's Medical College Hospital, Bangalore, India., Kodethoor D; Department of Paediatrics, St John's Medical College Hospital, Bangalore, India., K S; Department of Paediatrics, St John's Medical College Hospital, Bangalore, India., Lewin S; Department of Paediatrics, St John's Medical College Hospital, Bangalore, India.

المصدر: Paediatrics and international child health [Paediatr Int Child Health] 2024 Aug; Vol. 44 (2), pp. 52-54. Date of Electronic Publication: 2024 Apr 05.

نوع المنشور: Case Reports; Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101582666 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2046-9055 (Electronic) Linking ISSN: 20469047 NLM ISO Abbreviation: Paediatr Int Child Health Subsets: MEDLINE

مواضيع طبية MeSH: Osteopetrosis*/diagnosis , Osteopetrosis*/complications , Osteopetrosis*/diagnostic imaging, Humans ; Male ; Infant ; Radiography ; Developmental Disabilities/etiology ; Splenomegaly/diagnostic imaging ; Splenomegaly/etiology ; Hepatomegaly/diagnostic imaging ; Hepatomegaly/etiology ; Nystagmus, Pathologic/etiology ; Thrombocytopenia/diagnosis ; Anemia/etiology ; Anemia/diagnosis

المصدر: Journal of paediatrics and child health [J Paediatr Child Health] 2023 Aug; Vol. 59 (8), pp. 1007.

نوع المنشور: Case Reports

بيانات الدورية: Publisher: Blackwell Scientific Publications Country of Publication: Australia NLM ID: 9005421 Publication Model: Print Cited Medium: Internet ISSN: 1440-1754 (Electronic) Linking ISSN: 10344810 NLM ISO Abbreviation: J Paediatr Child Health Subsets: MEDLINE

مواضيع طبية MeSH: Exanthema*/diagnosis , Exanthema*/etiology , Hepatomegaly*/etiology , Splenomegaly*/etiology, Humans ; Infant, Newborn ; Buttocks ; Skin/pathology ; Syphilis, Congenital/diagnosis ; Treponema pallidum

المؤلفون: Yokoyama T; Department of Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan., Iwadare T; Department of Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan. iwnb.0522@gmail.com., Yamashita Y; Department of Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan.; Consultation Center for Liver Diseases, Shinshu University Hospital, Matsumoto, Japan., Momose A; Department of Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan., Ikeuchi H; Department of Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan., Kondo S; Department of Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan., Hashigami K; Department of Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan., Iwaya M; Department of Laboratory Medicine, Shinshu University School of Medicine, Matsumoto, Japan., Kimura T; Department of Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan.; Consultation Center for Liver Diseases, Shinshu University Hospital, Matsumoto, Japan., Umemura T; Department of Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan.; Consultation Center for Liver Diseases, Shinshu University Hospital, Matsumoto, Japan.

المصدر: Clinical journal of gastroenterology [Clin J Gastroenterol] 2024 Oct; Vol. 17 (5), pp. 915-921. Date of Electronic Publication: 2024 May 29.

نوع المنشور: Case Reports; Journal Article

بيانات الدورية: Publisher: Springer Japan Country of Publication: Japan NLM ID: 101477246 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1865-7265 (Electronic) Linking ISSN: 18657265 NLM ISO Abbreviation: Clin J Gastroenterol Subsets: MEDLINE

مواضيع طبية MeSH: Hepatitis, Alcoholic*/complications , Pancreatitis, Alcoholic*/complications , Tomography, X-Ray Computed*, Humans ; Female ; Adult ; Hepatomegaly/etiology ; Hepatomegaly/diagnostic imaging ; Splenomegaly/etiology ; Splenomegaly/diagnostic imaging ; Acute Disease ; Liver/pathology ; Liver/diagnostic imaging