المؤلفون: Rosochowicz MA; Doctoral School, Poznan University of Medical Sciences, Poznan, Poland. monika.rosochowicz@wco.pl.; Radiobiology Laboratory, Greater Poland Cancer Centre, Poznan, Poland. monika.rosochowicz@wco.pl.; Department of Orthopaedics and Traumatology, Poznan University of Medical Sciences, Poznan, Poland. monika.rosochowicz@wco.pl., Kulcenty K; Radiobiology Laboratory, Greater Poland Cancer Centre, Poznan, Poland., Suchorska WM; Radiobiology Laboratory, Greater Poland Cancer Centre, Poznan, Poland.; Department of Electroradiology, Poznan University of Medical Sciences, Poznan, Poland.

المصدر: Molecular diagnosis & therapy [Mol Diagn Ther] 2024 Jul; Vol. 28 (4), pp. 347-377. Date of Electronic Publication: 2024 May 08.

نوع المنشور: Journal Article; Systematic Review

بيانات الدورية: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 101264260 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-2000 (Electronic) Linking ISSN: 11771062 NLM ISO Abbreviation: Mol Diagn Ther Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*/genetics , Neoplasms*/pathology , High-Temperature Requirement A Serine Peptidase 1*/genetics , High-Temperature Requirement A Serine Peptidase 1*/metabolism , Serine Endopeptidases*/genetics , Serine Endopeptidases*/metabolism , High-Temperature Requirement A Serine Peptidase 2*/genetics , High-Temperature Requirement A Serine Peptidase 2*/metabolism , Gene Expression Regulation, Neoplastic*, Humans ; Mitochondrial Proteins/genetics ; Mitochondrial Proteins/metabolism

المؤلفون: Beaufort N; Institute for Stroke and Dementia Research (ISD), University Hospital, Ludwig Maximilian University of Munich, Munich, Germany., Ingendahl L; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany., Merdanovic M; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany., Schmidt A; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Graduate School of Systemic Neurosciences (GSN), LMU Munich, Munich, Germany., Podlesainski D; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany., Richter T; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany., Neumann T; Organic Chemistry, Faculty of Chemistry, University Duisburg-Essen, Essen, Germany., Kuszner M; Center of Medical Biotechnology, Faculty of Chemistry, University Duisburg-Essen, Essen, Germany., Vetter IR; Max-Planck-Institute of Molecular Physiology, Dortmund, Germany., Stege P; Max-Planck-Institute of Molecular Physiology, Dortmund, Germany., Burston SG; School of Biochemistry, University of Bristol, Biomedical Sciences Building, Bristol, UK., Filipovic A; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany., Ruiz-Blanco YB; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany., Bravo-Rodriguez K; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany.; Max-Planck-Institute of Molecular Physiology, Dortmund, Germany., Mieres-Perez J; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany.; Department of Biochemical and Chemical Engineering, Technical University Dortmund, Dortmund, Germany., Beuck C; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany., Uebel S; Max-Planck-Institute of Biochemistry, Martinsried, Germany., Zobawa M; Max-Planck-Institute of Biochemistry, Martinsried, Germany., Schillinger J; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany., Malik R; Institute for Stroke and Dementia Research (ISD), University Hospital, Ludwig Maximilian University of Munich, Munich, Germany., Todorov-Völgyi K; Institute for Stroke and Dementia Research (ISD), University Hospital, Ludwig Maximilian University of Munich, Munich, Germany., Rey J; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany., Roberti A; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany., Hagemeier B; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany., Wefers B; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Institute of Developmental Genetics (IDG), Helmholtz Zentrum München, Neuherberg, Germany., Müller SA; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Wurst W; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Institute of Developmental Genetics (IDG), Helmholtz Zentrum München, Neuherberg, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; Technische Universität München-Weihenstephan, Freising, Germany., Sanchez-Garcia E; Department of Biochemical and Chemical Engineering, Technical University Dortmund, Dortmund, Germany., Zimmermann A; Center of Medical Biotechnology, Faculty of Chemistry, University Duisburg-Essen, Essen, Germany., Hu XY; College of Material Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing, China., Clausen T; Research Institute of Molecular Pathology (IMP), Vienna, Austria., Huber R; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany.; Max-Planck-Institute of Biochemistry, Martinsried, Germany., Lichtenthaler SF; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Schmuck C; Center of Medical Biotechnology, Faculty of Chemistry, University Duisburg-Essen, Essen, Germany., Giese M; Organic Chemistry, Faculty of Chemistry, University Duisburg-Essen, Essen, Germany., Kaiser M; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany., Ehrmann M; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany. Michael.Ehrmann@uni-due.de., Dichgans M; Institute for Stroke and Dementia Research (ISD), University Hospital, Ludwig Maximilian University of Munich, Munich, Germany. dichgansmartin@gmail.com.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany. dichgansmartin@gmail.com.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany. dichgansmartin@gmail.com.

المصدر: Nature communications [Nat Commun] 2024 Jul 16; Vol. 15 (1), pp. 5944. Date of Electronic Publication: 2024 Jul 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: High-Temperature Requirement A Serine Peptidase 1*/metabolism , High-Temperature Requirement A Serine Peptidase 1*/genetics, Animals ; Humans ; Mice ; Protein Conformation ; Protein Multimerization ; HEK293 Cells ; Brain/metabolism ; Brain/pathology ; Mutation ; Loss of Function Mutation

المؤلفون: Navneet S; Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, United States., Ishii M; Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, United States., Rohrer B; Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, United States.; Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina, United States.; Ralph H. Johnson VA Medical Center, Division of Research, Charleston, South Carolina, United States.

المصدر: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2024 Jul 01; Vol. 65 (8), pp. 34.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE

مواضيع طبية MeSH: Elastin*/metabolism , Elastin*/genetics , Mice, Transgenic* , Retinal Pigment Epithelium*/metabolism , Retinal Pigment Epithelium*/pathology , High-Temperature Requirement A Serine Peptidase 1*/genetics , High-Temperature Requirement A Serine Peptidase 1*/metabolism , Tomography, Optical Coherence* , Disease Models, Animal* , Macular Degeneration*/genetics , Macular Degeneration*/metabolism, Animals ; Mice ; Autoantibodies/blood ; Immunoglobulin G/blood ; Aging ; Humans ; Complement C3/genetics ; Complement C3/metabolism ; Serine Endopeptidases/genetics ; Serine Endopeptidases/metabolism ; Immunohistochemistry ; Gene Expression Regulation

المؤلفون: Shao W; Department of Gynecology, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou City, China., Cui J, Wang W

المصدر: Journal of hypertension [J Hypertens] 2024 Jul 01; Vol. 42 (7), pp. 1154-1162. Date of Electronic Publication: 2024 Feb 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wolters Kluwer Health, Inc Country of Publication: Netherlands NLM ID: 8306882 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-5598 (Electronic) Linking ISSN: 02636352 NLM ISO Abbreviation: J Hypertens Subsets: MEDLINE

مواضيع طبية MeSH: Pre-Eclampsia*/genetics , Pre-Eclampsia*/metabolism , MicroRNAs*/genetics , MicroRNAs*/metabolism , Trophoblasts*/metabolism , High-Temperature Requirement A Serine Peptidase 1*/genetics , High-Temperature Requirement A Serine Peptidase 1*/metabolism , RNA, Circular*/genetics , RNA, Circular*/metabolism , Cell Proliferation* , Cell Movement*, Humans ; Female ; Pregnancy ; Adult

المؤلفون: Aspholm EE; Department of Chemistry and Molecular Biology, University of Gothenburg, Göteborg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Göteborg, Sweden., Lidman J; Department of Chemistry and Molecular Biology, University of Gothenburg, Göteborg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Göteborg, Sweden., Burmann BM; Department of Chemistry and Molecular Biology, University of Gothenburg, Göteborg, Sweden. bjorn.marcus.burmann@gu.se.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Göteborg, Sweden. bjorn.marcus.burmann@gu.se.

المصدر: Nature communications [Nat Commun] 2024 May 30; Vol. 15 (1), pp. 4592. Date of Electronic Publication: 2024 May 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: High-Temperature Requirement A Serine Peptidase 2*/metabolism , High-Temperature Requirement A Serine Peptidase 2*/genetics , Apoptosis* , PDZ Domains*, Humans ; Allosteric Regulation ; Substrate Specificity ; Mitochondria/metabolism ; Models, Molecular ; Magnetic Resonance Spectroscopy

المؤلفون: Li Y; Department of Early Discovery Biochemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Wei Y; Department of Early Discovery Biochemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Ultsch M; Department of Structural Biology, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Li W; Department of Early Discovery Biochemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Tang W; Department of Early Discovery Biochemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Tombling B; Department of Early Discovery Biochemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Gao X; Department of Early Discovery Biochemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Dimitrova Y; Department of Structural Biology, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Gampe C; Department of Discovery Chemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Fuhrmann J; Department of Early Discovery Biochemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Zhang Y; Department of Early Discovery Biochemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Hannoush RN; Department of Early Discovery Biochemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA. ramihannoush@gmail.com., Kirchhofer D; Department of Early Discovery Biochemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA. dak@gene.com.

المصدر: Nature communications [Nat Commun] 2024 May 22; Vol. 15 (1), pp. 4359. Date of Electronic Publication: 2024 May 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: High-Temperature Requirement A Serine Peptidase 1*/metabolism , High-Temperature Requirement A Serine Peptidase 1*/genetics , Catalytic Domain* , Peptides*/chemistry , Peptides*/metabolism , Peptides*/pharmacology, Humans ; Peptide Library ; Crystallography, X-Ray ; Protein Binding ; Cystine/chemistry ; Cystine/metabolism ; Models, Molecular

المؤلفون: Guo Y; Department of Neurology, Peking University First Hospital, Beijing, China.; Beijing Key Laboratory of Neurovascular Disease Discovery, Beijing, China., Peng Q; Department of Neurology, Peking University First Hospital, Beijing, China.; Beijing Key Laboratory of Neurovascular Disease Discovery, Beijing, China., Ling C; Department of Neurology, Peking University First Hospital, Beijing, China.; Beijing Key Laboratory of Neurovascular Disease Discovery, Beijing, China.

المصدر: JAMA neurology [JAMA Neurol] 2024 May 01; Vol. 81 (5), pp. 551-552.

نوع المنشور: Journal Article; Case Reports; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589536 Publication Model: Print Cited Medium: Internet ISSN: 2168-6157 (Electronic) Linking ISSN: 21686149 NLM ISO Abbreviation: JAMA Neurol Subsets: MEDLINE

مواضيع طبية MeSH: High-Temperature Requirement A Serine Peptidase 1*/genetics , Cerebral Small Vessel Diseases*/genetics , Cerebral Small Vessel Diseases*/diagnostic imaging, Humans ; Cerebral Hemorrhage/genetics ; Cerebral Hemorrhage/diagnostic imaging ; Male ; Heterozygote ; Female ; Middle Aged

المؤلفون: Williams BL; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology & Visual Sciences, University of Utah, Salt Lake City, Utah, United States., Zouache MA; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology & Visual Sciences, University of Utah, Salt Lake City, Utah, United States., Seager NA; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology & Visual Sciences, University of Utah, Salt Lake City, Utah, United States., Pappas CM; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology & Visual Sciences, University of Utah, Salt Lake City, Utah, United States., Liu J; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology & Visual Sciences, University of Utah, Salt Lake City, Utah, United States., Anstadt RA; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology & Visual Sciences, University of Utah, Salt Lake City, Utah, United States., Hubbard WC; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology & Visual Sciences, University of Utah, Salt Lake City, Utah, United States., Thomas J; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology & Visual Sciences, University of Utah, Salt Lake City, Utah, United States., Hageman JL; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology & Visual Sciences, University of Utah, Salt Lake City, Utah, United States., Mohler J; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology & Visual Sciences, University of Utah, Salt Lake City, Utah, United States., Richards BT; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology & Visual Sciences, University of Utah, Salt Lake City, Utah, United States., Hageman GS; Sharon Eccles Steele Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology & Visual Sciences, University of Utah, Salt Lake City, Utah, United States.

المصدر: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2024 Apr 01; Vol. 65 (4), pp. 34.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE

مواضيع طبية MeSH: High-Temperature Requirement A Serine Peptidase 1*/blood , High-Temperature Requirement A Serine Peptidase 1*/genetics , High-Temperature Requirement A Serine Peptidase 1*/metabolism , Macular Degeneration*/genetics , Macular Degeneration*/metabolism , Macular Degeneration*/diagnosis , Serine Endopeptidases*/genetics , Serine Endopeptidases*/metabolism , Vitreous Body*/metabolism, Aged ; Female ; Humans ; Male ; Chromosomes, Human, Pair 10/genetics ; Enzyme-Linked Immunosorbent Assay/methods ; Genetic Predisposition to Disease ; Risk Factors ; Sensitivity and Specificity

المؤلفون: Dennis DG; Medicinal Chemistry Knowledge Center, Sarafan ChEM-H, Stanford University, CA 94305, USA; Molecular Surgery Laboratory, Byers Eye Institute, Department of Ophthalmology, Stanford University, CA 94304, USA., Joo Sun Y; Molecular Surgery Laboratory, Byers Eye Institute, Department of Ophthalmology, Stanford University, CA 94304, USA., Parsons DE; Medicinal Chemistry Knowledge Center, Sarafan ChEM-H, Stanford University, CA 94305, USA; Molecular Surgery Laboratory, Byers Eye Institute, Department of Ophthalmology, Stanford University, CA 94304, USA., Mahajan VB; Molecular Surgery Laboratory, Byers Eye Institute, Department of Ophthalmology, Stanford University, CA 94304, USA; Veterans Affairs Palo Alto Health Care System, CA 94304, USA. Electronic address: vinit.mahajan@stanford.com., Smith M; Medicinal Chemistry Knowledge Center, Sarafan ChEM-H, Stanford University, CA 94305, USA. Electronic address: mxsmith@stanford.edu.

المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2024 Sep 01; Vol. 109, pp. 129814. Date of Electronic Publication: 2024 May 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

مواضيع طبية MeSH: High-Temperature Requirement A Serine Peptidase 1*/metabolism , Serine Endopeptidases*/metabolism, Structure-Activity Relationship ; Humans ; Serine Proteinase Inhibitors/pharmacology ; Serine Proteinase Inhibitors/chemistry ; Serine Proteinase Inhibitors/chemical synthesis ; Molecular Structure ; Dose-Response Relationship, Drug ; Small Molecule Libraries/chemistry ; Small Molecule Libraries/pharmacology ; Small Molecule Libraries/chemical synthesis

المؤلفون: Pera EM; Vertebrate Developmental Biology Laboratory, Department of Laboratory Medicine, Lund Stem Cell Center, University of Lund, Lund, Sweden., Nilsson-De Moura J; Vertebrate Developmental Biology Laboratory, Department of Laboratory Medicine, Lund Stem Cell Center, University of Lund, Lund, Sweden., Pomeshchik Y; iPSC Laboratory for CNS Disease Modeling, Department of Experimental Medical Science, Lund Stem Cell Center, Strategic Research Area MultiPark, Lund University, Lund, Sweden., Roybon L; iPSC Laboratory for CNS Disease Modeling, Department of Experimental Medical Science, Lund Stem Cell Center, Strategic Research Area MultiPark, Lund University, Lund, Sweden., Milas I; Vertebrate Developmental Biology Laboratory, Department of Laboratory Medicine, Lund Stem Cell Center, University of Lund, Lund, Sweden.

المصدر: ELife [Elife] 2024 Apr 18; Vol. 12. Date of Electronic Publication: 2024 Apr 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: High-Temperature Requirement A Serine Peptidase 1*/metabolism , Neural Crest*/embryology , Neural Crest*/metabolism , Serpin E2*/metabolism, Animals ; Cell Movement/genetics ; Fibroblast Growth Factors/metabolism ; Signal Transduction ; Xenopus laevis/metabolism ; Xenopus Proteins/genetics ; Xenopus Proteins/metabolism