يعرض 1 - 4 نتائج من 4 نتيجة بحث عن '"HMWS, Higher molecular weight species"', وقت الاستعلام: 0.98s تنقيح النتائج
  1. 1
    The effect of mAb and excipient cryoconcentration on long-term frozen storage stability – Part 1: Higher molecular weight species and subvisible particle formation

    المؤلفون: Oliver Bluemel, Moritz Anuschek, Jakob W. Buecheler, Georg Hoelzl, Karoline Bechtold-Peters, Wolfgang Friess

    المصدر: International Journal of Pharmaceutics: X, Vol 4, Iss, Pp 100108-(2022)
    International Journal of Pharmaceutics: X

    مصطلحات موضوعية: Monoclonal antibody, SEC, Size-exclusion chromatography, HPLC, High-performance liquid chromatography, PES, Polyethersulfone, Large-scale freezing, Pharmaceutical Science, FCM, Freeze-concentrated matrix, Tg′, Glass transition temperature of the maximally freeze-concentrated solution, Frozen storage, RS1-441, Pharmacy and materia medica, SVP, Subvisible particle, mAb, Monoclonal antibody, DSC, Differential scanning calorimetry, HMWS, Higher molecular weight species, Stability, Research Paper, Cryoconcentration

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1e879d7a95015ba4b711cb5c437c93
    http://www.sciencedirect.com/science/article/pii/S2590156721000372

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  2. 2
    The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - part 2: Aggregate formation and oxidation

    المؤلفون: Oliver Bluemel, Jakob W. Buecheler, Astrid Hauptmann, Georg Hoelzl, Karoline Bechtold-Peters, Wolfgang Friess

    المصدر: International Journal of Pharmaceutics: X
    International Journal of Pharmaceutics: X, Vol 4, Iss, Pp 100109-(2022)

    مصطلحات موضوعية: frozen storage, SEC, Size-exclusion chromatography, cryoconcentration, PES, Polyethersulfone, Pharmaceutical Science, HPLC, High performance liquid chromatography, stability, FCM, Freeze-concentrated matrix, HPW, Highly purified water, Tg′, Glass transition temperature of the maximally freeze-concentrated solution, RS1-441, OD350, Optical density at 350 nm, Pharmacy and materia medica, monoclonal antibody, DLS, Dynamic light scattering, SVP, Subvisible particle, mAb, Monoclonal antibody, large-scale freezing, HMWS, Higher molecular weight species, Research Paper

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48554eb16d78e5b0127bc646e9ca6ea7
    https://pubmed.ncbi.nlm.nih.gov/35024604

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  3. 3
    دورية أكاديمية
    The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - Part 1: Higher molecular weight species and subvisible particle formation.

    المؤلفون: Bluemel O; Pharmaceutical Technology and Biopharmaceutics, Department of Pharmacy, Ludwig-Maximilians-Universitaet Muenchen, 81377 Munich, Germany., Anuschek M; Pharmaceutical Technology and Biopharmaceutics, Department of Pharmacy, Ludwig-Maximilians-Universitaet Muenchen, 81377 Munich, Germany., Buecheler JW; Technical Research and Development, Novartis Pharma AG, 4002 Basel, Switzerland., Hoelzl G; Sandoz GmbH, 6336 Langkampfen, Austria., Bechtold-Peters K; Technical Research and Development, Novartis Pharma AG, 4002 Basel, Switzerland., Friess W; Pharmaceutical Technology and Biopharmaceutics, Department of Pharmacy, Ludwig-Maximilians-Universitaet Muenchen, 81377 Munich, Germany.

    المصدر: International journal of pharmaceutics: X [Int J Pharm X] 2021 Dec 25; Vol. 4, pp. 100108. Date of Electronic Publication: 2021 Dec 25 (Print Publication: 2022).

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101753452 Publication Model: eCollection Cited Medium: Internet ISSN: 2590-1567 (Electronic) Linking ISSN: 25901567 NLM ISO Abbreviation: Int J Pharm X Subsets: PubMed not MEDLINE

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  4. 4
    دورية أكاديمية
    The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - part 2: Aggregate formation and oxidation.

    المؤلفون: Bluemel O; Pharmaceutical Technology and Biopharmaceutics, Department of Pharmacy, Ludwig-Maximilians-Universitaet Muenchen, 81377 Munich, Germany., Buecheler JW; Technical Research and Development, Novartis Pharma AG, 4002 Basel, Switzerland., Hauptmann A; Sandoz GmbH, 6336 Langkampfen, Austria., Hoelzl G; Sandoz GmbH, 6336 Langkampfen, Austria., Bechtold-Peters K; Technical Research and Development, Novartis Pharma AG, 4002 Basel, Switzerland., Friess W; Pharmaceutical Technology and Biopharmaceutics, Department of Pharmacy, Ludwig-Maximilians-Universitaet Muenchen, 81377 Munich, Germany.

    المصدر: International journal of pharmaceutics: X [Int J Pharm X] 2021 Dec 25; Vol. 4, pp. 100109. Date of Electronic Publication: 2021 Dec 25 (Print Publication: 2022).

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101753452 Publication Model: eCollection Cited Medium: Internet ISSN: 2590-1567 (Electronic) Linking ISSN: 25901567 NLM ISO Abbreviation: Int J Pharm X Subsets: PubMed not MEDLINE

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