المؤلفون: Ayako Makino, Ankit A. Desai, Ramon J. Ayon, Yali Gu, Ziyi Wang, Qian Zhang, Guofei Zhou, Shanshan Song, Franz Rischard, Jiwang Chen, Jason X.-J. Yuan, Kang Wu, Sujana Vinjamuri, Angela Balistrieri, Haiyang Tang, Rebecca Vanderpool, Joe G.N. Garcia, Jian Wang, Stephen M. Black

المصدر: JACC. Basic to translational science, vol 3, iss 6
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 744-762 (2018)

مصطلحات موضوعية: phosphatase and tensin homolog, lcsh:Diseases of the circulatory (Cardiovascular) system, Raptor, regulatory associated protein of mammalian target of rapamycin, PH, Rictor, rapamycin insensitive companion of mammalian target of rapamycin, mTORC1, right ventricle, Pharmacology, Cardiovascular, PI3K, mTORC2, platelet-derived growth factor, smooth muscle, PRECLINICAL RESEARCH, GPCR, 0302 clinical medicine, pulmonary arterial hypertension, PASMC, Lung, PDGFR, platelet-derived growth factor receptor, WT, mTORC1, mammalian target of rapamycin complex 1, rapamycin insensitive companion of mammalian target of rapamycin, HPH, hypoxia-induced pulmonary hypertension, PAEC, 3. Good health, pulmonary arterial endothelial cell, TKR, endothelial cell, Cardiology and Cardiovascular Medicine, PA, Clinical Sciences, phosphorylated AKT, 03 medical and health sciences, Right ventricular hypertrophy, pulmonary artery, G protein-coupled receptor, GPCR, G protein-coupled receptor, pulmonary arterial smooth muscle cell, EC, endothelial cell, mammalian target of rapamycin complex 2, mammalian target of rapamycin complex 1, medicine.disease, pAKT, phosphorylated AKT, WT, wild-type, 030104 developmental biology, lcsh:RC666-701, 0301 basic medicine, PTEN, PVR, Cardiorespiratory Medicine and Haematology, 030204 cardiovascular system & hematology, PDGF, platelet-derived growth factor, SM, smooth muscle, RVSP, hypoxia-induced pulmonary hypertension, RVSP, right ventricular systolic pressure, pulmonary hypertension, right ventricular hypertrophy, regulatory associated protein of mammalian target of rapamycin, SM, phosphoinositide 3-kinase, PDGF, PAEC, pulmonary arterial endothelial cell, Raptor, PA, pulmonary artery, Heart Disease, medicine.anatomical_structure, HPH, pulmonary vascular resistance, mTORC2, mammalian target of rapamycin complex 2, mTOR, PAH, pulmonary arterial hypertension, PI3K, phosphoinositide 3-kinase, PASMC, pulmonary arterial smooth muscle cell, PDGFR, Forkhead box O3a, pAKT, PH, pulmonary hypertension, PVR, pulmonary vascular resistance, Rictor, FOXO3a, Forkhead box O3a, Rare Diseases, Growth factor receptor, TKR, tyrosine kinase receptor, medicine, right ventricular systolic pressure, FOXO3a, PI3K/AKT/mTOR pathway, wild-type, EC, business.industry, RVH, right ventricular hypertrophy, PAH, platelet-derived growth factor receptor, Pulmonary hypertension, PTEN, phosphatase and tensin homolog, Vascular resistance, tyrosine kinase receptor, business, RVH

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1d147fc74d88a884f1e521e7ef3c53
https://doi.org/10.1016/j.jacbts.2018.08.009

المؤلفون: Tang H; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Wu K; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Wang J; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Vinjamuri S; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Gu Y; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Song S; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Wang Z; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Zhang Q; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.; Department of Physiology, The University of Arizona College of Medicine, Tucson, Arizona., Balistrieri A; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Ayon RJ; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Rischard F; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Vanderpool R; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Chen J; Department of Pediatrics, University of Illinois College of Medicine, Chicago, Illinois., Zhou G; State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.; Department of Pediatrics, University of Illinois College of Medicine, Chicago, Illinois., Desai AA; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; Division of Cardiology, Department of Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Black SM; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; Department of Physiology, The University of Arizona College of Medicine, Tucson, Arizona., Garcia JGN; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; Department of Physiology, The University of Arizona College of Medicine, Tucson, Arizona.; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Yuan JX; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.; Department of Physiology, The University of Arizona College of Medicine, Tucson, Arizona., Makino A; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; Department of Physiology, The University of Arizona College of Medicine, Tucson, Arizona.

المصدر: JACC. Basic to translational science [JACC Basic Transl Sci] 2018 Dec 31; Vol. 3 (6), pp. 744-762. Date of Electronic Publication: 2018 Dec 31 (Print Publication: 2018).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier on behalf of the American College of Cardiology Foundation Country of Publication: United States NLM ID: 101677259 Publication Model: eCollection Cited Medium: Internet ISSN: 2452-302X (Electronic) Linking ISSN: 2452302X NLM ISO Abbreviation: JACC Basic Transl Sci Subsets: PubMed not MEDLINE