المؤلفون: Huynh NPT; Center for Translational Neuromedicine, University of Copenhagen, Faculty of Health and Medical Sciences, 2200 Copenhagen, Denmark.; Center for Translational Neuromedicine and Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA., Osipovitch M; Center for Translational Neuromedicine, University of Copenhagen, Faculty of Health and Medical Sciences, 2200 Copenhagen, Denmark., Foti R; Center for Translational Neuromedicine, University of Copenhagen, Faculty of Health and Medical Sciences, 2200 Copenhagen, Denmark., Bates J; Center for Translational Neuromedicine and Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA., Mansky B; Center for Translational Neuromedicine and Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA., Cano JC; Center for Translational Neuromedicine and Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA., Benraiss A; Center for Translational Neuromedicine and Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA., Zhao C; Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Lu QR; Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Goldman SA; Center for Translational Neuromedicine, University of Copenhagen, Faculty of Health and Medical Sciences, 2200 Copenhagen, Denmark.; Center for Translational Neuromedicine and Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA.

المصدر: Brain : a journal of neurology [Brain] 2024 Sep 03; Vol. 147 (9), pp. 3099-3112.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE

مواضيع طبية MeSH: Huntington Disease*/genetics , Huntington Disease*/metabolism , Huntington Disease*/pathology , Schizophrenia*/genetics , Schizophrenia*/metabolism , Neuroglia*/metabolism, Humans ; Oligodendrocyte Transcription Factor 2/metabolism ; Oligodendrocyte Transcription Factor 2/genetics ; Gene Regulatory Networks ; Pluripotent Stem Cells/metabolism

المؤلفون: Franklin GL; Internal Medicine Department, Medical School, Pontifical Catholic University of Paraná, Curitiba, PR 80215-901, Brazil.

المصدر: Postgraduate medical journal [Postgrad Med J] 2024 Aug 16; Vol. 100 (1187), pp. 699-700.

نوع المنشور: Journal Article; Personal Narrative

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0234135 Publication Model: Print Cited Medium: Internet ISSN: 1469-0756 (Electronic) Linking ISSN: 00325473 NLM ISO Abbreviation: Postgrad Med J Subsets: MEDLINE

مواضيع طبية MeSH: Huntington Disease*/psychology , Huntington Disease*/therapy , Physician-Patient Relations* , Emotions*, Humans

المؤلفون: Saade J; The Ottawa Hospital Research Institute, Ottawa, ON, Canada., Mestre TA; The Ottawa Hospital Research Institute, Ottawa, ON, Canada. tmestre@toh.ca.; The University of Ottawa Brain and Research Institute, Ottawa, ON, Canada. tmestre@toh.ca.; Parkinson's Disease and Movement Disorder Clinic, Division of Neurology, Department of Medicine, The Ottawa Hospital, Ottawa, ON, Canada. tmestre@toh.ca.

المصدر: Current neurology and neuroscience reports [Curr Neurol Neurosci Rep] 2024 Aug; Vol. 24 (8), pp. 255-264. Date of Electronic Publication: 2024 Jun 11.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Current Science Inc Country of Publication: United States NLM ID: 100931790 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1534-6293 (Electronic) Linking ISSN: 15284042 NLM ISO Abbreviation: Curr Neurol Neurosci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Huntington Disease*/therapy , Huntington Disease*/genetics , Huntington Disease*/drug therapy, Humans ; Oligonucleotides, Antisense/therapeutic use ; Huntingtin Protein/genetics ; Animals ; Drug Development

المؤلفون: Luo C; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, China., Yang J; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, China.

المصدر: Aging cell [Aging Cell] 2024 Aug; Vol. 23 (8), pp. e14285. Date of Electronic Publication: 2024 Jul 23.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE

مواضيع طبية MeSH: Huntington Disease*/pathology , Huntington Disease*/metabolism , Huntington Disease*/genetics , Autophagy* , Neurons*/metabolism , Neurons*/pathology , Cellular Reprogramming* , Aging*/pathology, Humans ; Animals

المؤلفون: Gonzalez-Baez Ardisana P; Center of Research in Science of Health (CICSA), Faculty of Science of Health of Anahuac University, Huixquilucan, México State, Mexico., Solís-Mata JS; Center of Research in Science of Health (CICSA), Faculty of Science of Health of Anahuac University, Huixquilucan, México State, Mexico., Carrillo-Ruiz JD; Stereotactic and Functional Neurosurgery and Radiosurgery at Hospital General de Mexico & Research Direction at Hospital General de Mexico, México City, Mexico; Neuroscience Coordination, Psychology Faculty of Anahuac University, Huixquilucan, México State, Mexico. Electronic address: damian.carrillo@anahuac.mx.

المصدر: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2024 Aug; Vol. 125, pp. 107048. Date of Electronic Publication: 2024 Jun 27.

نوع المنشور: Journal Article; Systematic Review; Review

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9513583 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5126 (Electronic) Linking ISSN: 13538020 NLM ISO Abbreviation: Parkinsonism Relat Disord Subsets: MEDLINE

مواضيع طبية MeSH: Huntington Disease*/surgery , Huntington Disease*/therapy , Deep Brain Stimulation*, Humans ; Neurosurgical Procedures/methods

المؤلفون: Bahar R; Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Darabi S; Cellular and Molecular Research Center, Research Institute for Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran., Norouzian M; Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Roustaei S; Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Hearing Disorders Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Torkamani-Dordshaikh S; Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Hasanzadeh M; Hearing Disorders Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Vakili K; Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Fathi M; Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Khodagholi F; Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Kaveh N; Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Jahanbaz S; Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Moghaddam MH; Department of Anatomical Sciences, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran., Abbaszadeh HA; Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: Dr.Abbaszadeh@sbmu.ac.ir., Aliaghaei A; Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: aghaei60@gmail.com.

المصدر: Journal of chemical neuroanatomy [J Chem Neuroanat] 2024 Jul; Vol. 138, pp. 102419. Date of Electronic Publication: 2024 Apr 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Publisher Country of Publication: Netherlands NLM ID: 8902615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6300 (Electronic) Linking ISSN: 08910618 NLM ISO Abbreviation: J Chem Neuroanat Subsets: MEDLINE

مواضيع طبية MeSH: Extracellular Vesicles*/metabolism , Huntington Disease*/metabolism , Huntington Disease*/pathology , Disease Models, Animal* , Gliosis*/pathology , Neuroprotective Agents*/pharmacology , Fetal Blood*, Animals ; Rats ; Humans ; Male ; Corpus Striatum/metabolism ; Corpus Striatum/pathology ; Rats, Wistar ; Nitro Compounds ; Propionates

المؤلفون: Noureldeen ME; Biochemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Ainy St., Cairo, 11562, Egypt., Shahin NN; Biochemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Ainy St., Cairo, 11562, Egypt., Amin HAA; Pathology Department, Faculty of Medicine, Helwan University, Cairo, 11795, Egypt., El-Sawalhi MM; Biochemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Ainy St., Cairo, 11562, Egypt., Ghaiad HR; Biochemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Ainy St., Cairo, 11562, Egypt. heba.mosalam@pharma.cu.edu.eg.

المصدر: Molecular medicine (Cambridge, Mass.) [Mol Med] 2024 Sep 26; Vol. 30 (1), pp. 158. Date of Electronic Publication: 2024 Sep 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Electronic Cited Medium: Internet ISSN: 1528-3658 (Electronic) Linking ISSN: 10761551 NLM ISO Abbreviation: Mol Med Subsets: MEDLINE

مواضيع طبية MeSH: Nitro Compounds* , Huntington Disease*/drug therapy , Huntington Disease*/metabolism , Huntington Disease*/chemically induced , NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism , Inflammasomes*/metabolism , Sesquiterpenes*/pharmacology , Sesquiterpenes*/therapeutic use , Propionates*/pharmacology , Astrocytes*/metabolism , Astrocytes*/drug effects , Microglia*/metabolism , Microglia*/drug effects, Animals ; Male ; Rats ; Disease Models, Animal ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Rats, Wistar ; Corpus Striatum/metabolism ; Corpus Striatum/drug effects ; Behavior, Animal/drug effects

المؤلفون: Chakraborty A; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555., Sreenivasmurthy SG; Department of Neurology, Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch, Galveston, TX 77555., Miller W; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093., Huai W; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093., Biswas T; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093., Mandal SM; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555.; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093., Boscá L; Instituto de Investigaciones Biomédicas Sols-Morreale, (Consejo Superior de Investigaciones Científicas- Universidad Autónoma de Madrid), and Centro de Investigación en Red en Enfermedades Cardiovasculares, Madrid ES-28040, Spain., Krishnan B; Department of Neurology, Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch, Galveston, TX 77555., Ghosh G; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093., Hazra T; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Sep 24; Vol. 121 (39), pp. e2406308121. Date of Electronic Publication: 2024 Sep 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: DNA Repair* , DNA Repair Enzymes*/metabolism , DNA Repair Enzymes*/genetics , Fructosediphosphates*/metabolism , Huntington Disease*/metabolism , Huntington Disease*/genetics , Huntington Disease*/drug therapy, Animals ; Humans ; Mice ; Disease Models, Animal ; DNA Breaks, Double-Stranded ; Drosophila ; Drosophila melanogaster ; Neurons/metabolism ; Phosphofructokinase-2/metabolism ; Phosphofructokinase-2/genetics ; Phosphotransferases (Alcohol Group Acceptor) ; Phosphotransferases (Phosphate Group Acceptor)/metabolism ; Phosphotransferases (Phosphate Group Acceptor)/genetics

المؤلفون: Ethirajulu AK; Department of Pharmaceutical Sciences, University at Buffalo, The State University of New York, 355 Pharmacy, Buffalo, New York, USA., Sriramoju V; Department of Pharmaceutical Sciences, University at Buffalo, The State University of New York, 355 Pharmacy, Buffalo, New York, USA., Bhat AG; Department of Pharmaceutical Sciences, University at Buffalo, The State University of New York, 355 Pharmacy, Buffalo, New York, USA., Ramanathan M; Department of Pharmaceutical Sciences, University at Buffalo, The State University of New York, 355 Pharmacy, Buffalo, New York, USA. Murali@Buffalo.Edu.; Department of Neurology, University at Buffalo, The State University of New York, Buffalo, New York, 14214-8033, USA. Murali@Buffalo.Edu.

المصدر: The AAPS journal [AAPS J] 2024 Sep 17; Vol. 26 (6), pp. 106. Date of Electronic Publication: 2024 Sep 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE

مواضيع طبية MeSH: Huntingtin Protein*/genetics , Huntingtin Protein*/metabolism , Huntington Disease*/genetics , Huntington Disease*/drug therapy , Huntington Disease*/metabolism, Humans ; Pharmacogenetics/methods ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/chemistry ; Nerve Tissue Proteins/metabolism ; Artificial Intelligence ; Algorithms ; Peptides/genetics ; Peptides/chemistry ; Models, Molecular ; Amino Acid Sequence

المؤلفون: Deo A; Department of Biotechnology, Savitribai Phule Pune University, Ganeshkhind, Pune, 411007, India., Ghosh R; Indian Institute of Science and Educational Research (IISER), Dr. Homi Bhabha Road, Pashan, Pune, 411008, India., Ahire S; Department of Biotechnology, Savitribai Phule Pune University, Ganeshkhind, Pune, 411007, India., Marathe S; Department of Biotechnology, Savitribai Phule Pune University, Ganeshkhind, Pune, 411007, India., Majumdar A; National Centre for Cell Sciences, Inside Savitribai Phule Pune University Campus, Ganeshkhind, Pune, 411007, India. mamitava@nccs.res.in., Bose T; Department of Biotechnology, Savitribai Phule Pune University, Ganeshkhind, Pune, 411007, India. tania.bose@gmail.com.

المصدر: Scientific reports [Sci Rep] 2024 Sep 06; Vol. 14 (1), pp. 20867. Date of Electronic Publication: 2024 Sep 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Drosophila Proteins*/metabolism , Drosophila Proteins*/genetics , HSP40 Heat-Shock Proteins*/genetics , HSP40 Heat-Shock Proteins*/metabolism , Huntingtin Protein*/genetics , Huntingtin Protein*/metabolism , Huntington Disease*/genetics , Huntington Disease*/metabolism , Huntington Disease*/pathology, Animals ; Humans ; Animals, Genetically Modified ; Disease Models, Animal ; Drosophila ; Drosophila melanogaster ; Protein Aggregates ; Protein Aggregation, Pathological/genetics ; Saccharomyces cerevisiae