المؤلفون: Tsuchikama K; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA. kyoji.tsuchikama@uth.tmc.edu., Anami Y; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Ha SYY; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Yamazaki CM; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.

المصدر: Nature reviews. Clinical oncology [Nat Rev Clin Oncol] 2024 Mar; Vol. 21 (3), pp. 203-223. Date of Electronic Publication: 2024 Jan 08.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101500077 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1759-4782 (Electronic) Linking ISSN: 17594774 NLM ISO Abbreviation: Nat Rev Clin Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Immunoconjugates*/chemistry , Antineoplastic Agents*/therapeutic use , Neoplasms*, Humans ; Antibodies, Monoclonal/adverse effects ; Pharmaceutical Preparations

المؤلفون: Ha SYY; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Anami Y; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Yamazaki CM; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Xiong W; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Haase CM; Department of Pediatric Surgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Olson SD; Department of Pediatric Surgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Lee J; Section of Translational Breast Cancer Research, Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Ueno NT; Section of Translational Breast Cancer Research, Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Zhang N; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., An Z; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Tsuchikama K; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.

المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2022 Sep 06; Vol. 21 (9), pp. 1449-1461.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/therapeutic use , Immunoconjugates*/metabolism , Immunoconjugates*/pharmacology, Ado-Trastuzumab Emtansine ; Animals ; Cell Line, Tumor ; Citrulline ; Humans ; Mice ; Peptide Hydrolases ; Therapeutic Index

المؤلفون: Anami Y; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Center at Houston, Houston, TX 77054, USA., Otani Y; Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Xiong W; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Center at Houston, Houston, TX 77054, USA., Ha SYY; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Center at Houston, Houston, TX 77054, USA., Yamaguchi A; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Center at Houston, Houston, TX 77054, USA., Rivera-Caraballo KA; Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Zhang N; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Center at Houston, Houston, TX 77054, USA., An Z; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Center at Houston, Houston, TX 77054, USA., Kaur B; Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Tsuchikama K; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Center at Houston, Houston, TX 77054, USA. Electronic address: kyoji.tsuchikama@uth.tmc.edu.

المصدر: Cell reports [Cell Rep] 2022 May 24; Vol. 39 (8), pp. 110839.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/therapeutic use , Brain Neoplasms*/drug therapy , Glioblastoma*/drug therapy , Immunoconjugates*/pharmacokinetics , Immunoconjugates*/therapeutic use, Cell Line, Tumor ; Humans ; Pharmaceutical Preparations

المؤلفون: Chu JCH; Department of Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China. dkpn@cuhk.edu.hk., Shao C; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China. clarence-tt.wong@polyu.edu.hk., Ha SYY; Department of Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China. dkpn@cuhk.edu.hk., Fong WP; School of Life Sciences, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China., Wong CTT; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China. clarence-tt.wong@polyu.edu.hk., Ng DKP; Department of Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China. dkpn@cuhk.edu.hk.

المصدر: Biomaterials science [Biomater Sci] 2021 Nov 23; Vol. 9 (23), pp. 7832-7837. Date of Electronic Publication: 2021 Nov 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101593571 Publication Model: Electronic Cited Medium: Internet ISSN: 2047-4849 (Electronic) Linking ISSN: 20474830 NLM ISO Abbreviation: Biomater Sci Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*/drug therapy , Photochemotherapy*, Cell Line, Tumor ; Erythrocytes ; Humans ; Peptides ; Photosensitizing Agents/therapeutic use

المؤلفون: Martínez-Edo G; Grup d'Enginyera de Materials (GEMAT), Institut Químic de Sarrià, Universitat Ramon Llull, Via Augusta 390, 08017, Barcelona, Spain., Xue EY; Department of Chemistry, The Chinese University of Hong Kong Shatin, N.T., Hong Kong, China., Ha SYY; Department of Chemistry, The Chinese University of Hong Kong Shatin, N.T., Hong Kong, China., Pontón I; Grup d'Enginyera de Materials (GEMAT), Institut Químic de Sarrià, Universitat Ramon Llull, Via Augusta 390, 08017, Barcelona, Spain., González-Delgado JA; Department of Organic Chemistry and Institute for Advanced Research in Chemistry (IAdChem), Universidad Autónoma de Madrid, c/ Francisco Tomás y Valiente 7 Cantoblanco, 28049, Madrid, Spain., Borrós S; Grup d'Enginyera de Materials (GEMAT), Institut Químic de Sarrià, Universitat Ramon Llull, Via Augusta 390, 08017, Barcelona, Spain., Torres T; Department of Organic Chemistry and Institute for Advanced Research in Chemistry (IAdChem), Universidad Autónoma de Madrid, c/ Francisco Tomás y Valiente 7 Cantoblanco, 28049, Madrid, Spain.; IMDEA-Nanociencia, c/ Faraday 9, Campus de Cantoblanco, 28049, Madrid, Spain., Ng DKP; Department of Chemistry, The Chinese University of Hong Kong Shatin, N.T., Hong Kong, China., Sánchez-García D; Grup d'Enginyera de Materials (GEMAT), Institut Químic de Sarrià, Universitat Ramon Llull, Via Augusta 390, 08017, Barcelona, Spain.

المصدر: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2021 Oct 21; Vol. 27 (59), pp. 14610-14618. Date of Electronic Publication: 2021 Oct 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765 (Electronic) Linking ISSN: 09476539 NLM ISO Abbreviation: Chemistry Subsets: MEDLINE

مواضيع طبية MeSH: Nanoparticles* , Photochemotherapy*, Doxorubicin ; Drug Delivery Systems ; Drug Liberation ; Humans ; Silicon Dioxide

المؤلفون: Yamaguchi A; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Anami Y; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Ha SYY; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Roeder TJ; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Xiong W; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Lee J; Section of Translational Breast Cancer Research, Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Ueno NT; Section of Translational Breast Cancer Research, Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Zhang N; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., An Z; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Tsuchikama K; Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA. Electronic address: Kyoji.Tsuchikama@uth.tmc.edu.

المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2021 Feb 15; Vol. 32, pp. 116013. Date of Electronic Publication: 2021 Jan 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Folate Receptor 1/*antagonists & inhibitors , Immunoconjugates/*pharmacology , Receptor, ErbB-2/*antagonists & inhibitors , Small Molecule Libraries/*pharmacology, Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Folate Receptor 1/metabolism ; Humans ; Immunoconjugates/chemistry ; Molecular Structure ; Receptor, ErbB-2/metabolism ; Small Molecule Libraries/chemical synthesis ; Small Molecule Libraries/chemistry ; Structure-Activity Relationship

المؤلفون: Ha SYY; Department of Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China. dkpn@cuhk.edu.hk., Ng DKP

المصدر: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Dec 04; Vol. 56 (93), pp. 14601-14604. Date of Electronic Publication: 2020 Nov 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem Commun (Camb) Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Wong CTT; Department of Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China., Chu JCH; Department of Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China., Ha SYY; Department of Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China., Wong RCH; Department of Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China., Dai G; Department of Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China., Kwong TT; Department of Clinical Oncology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China., Wong CH; Department of Clinical Oncology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China., Ng DKP; Department of Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China.

المصدر: Organic letters [Org Lett] 2020 Sep 18; Vol. 22 (18), pp. 7098-7102. Date of Electronic Publication: 2020 Aug 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Ha SYY, Zhou Y, Fong WP, Ng DKP

المصدر: Journal of medicinal chemistry [J Med Chem] 2020 Aug 13; Vol. 63 (15), pp. 8512-8523. Date of Electronic Publication: 2020 Jul 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*administration & dosage , Bibenzyls/*administration & dosage , Indoles/*administration & dosage , Organometallic Compounds/*administration & dosage , Photosensitizing Agents/*administration & dosage , Prodrugs/*administration & dosage, Antineoplastic Agents/pharmacokinetics ; Antineoplastic Agents/pharmacology ; Benzenesulfonates/administration & dosage ; Benzenesulfonates/pharmacokinetics ; Benzenesulfonates/pharmacology ; Bibenzyls/pharmacokinetics ; Bibenzyls/pharmacology ; Drug Delivery Systems ; Glutathione/metabolism ; HCT116 Cells ; Hep G2 Cells ; Humans ; Indoles/pharmacokinetics ; Indoles/pharmacology ; Isoindoles ; Neoplasms/drug therapy ; Organometallic Compounds/pharmacokinetics ; Organometallic Compounds/pharmacology ; Photochemotherapy ; Photosensitizing Agents/pharmacokinetics ; Photosensitizing Agents/pharmacology ; Prodrugs/pharmacokinetics ; Prodrugs/pharmacology ; Zinc Compounds

المؤلفون: Ha SYY; Department of Chemistry, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong, China., Wong RCH; Department of Chemistry, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong, China., Wong CTT; Department of Chemistry, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong, China., Ng DKP; Department of Chemistry, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong, China. Electronic address: dkpn@cuhk.edu.hk.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2019 Jul 15; Vol. 174, pp. 56-65. Date of Electronic Publication: 2019 Apr 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Coordination Complexes/*pharmacology , Glutathione/*metabolism , Indoles/*pharmacology , Peptides, Cyclic/*pharmacology , Photosensitizing Agents/*pharmacology, Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/metabolism ; Antineoplastic Agents/radiation effects ; Benzenesulfonates/chemical synthesis ; Benzenesulfonates/metabolism ; Benzenesulfonates/pharmacology ; Benzenesulfonates/radiation effects ; Cell Line, Tumor ; Coordination Complexes/chemical synthesis ; Coordination Complexes/metabolism ; Coordination Complexes/radiation effects ; Fluorescence ; HEK293 Cells ; Humans ; Indoles/chemical synthesis ; Indoles/metabolism ; Indoles/radiation effects ; Integrins/metabolism ; Light ; Peptides, Cyclic/chemical synthesis ; Peptides, Cyclic/metabolism ; Peptides, Cyclic/radiation effects ; Photosensitizing Agents/chemical synthesis ; Photosensitizing Agents/metabolism ; Photosensitizing Agents/radiation effects ; Singlet Oxygen/metabolism ; Zinc/chemistry