المؤلفون: Farese, Robert, Xu, N, Zhang, SO, Cole, RA, McKinney, SA, Guo, F, Haas, JT, Bobba, S, Farese, RV, Mak, HY

URL الوصول: https://escholarship.org/uc/item/8vf9x7ch

المؤلفون: L'homme L; Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1011-EGID, Lille, France. laurent.l-homme@inserm.fr., Sermikli BP; Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1011-EGID, Lille, France., Haas JT; Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1011-EGID, Lille, France., Fleury S; Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1011-EGID, Lille, France., Quemener S; Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1011-EGID, Lille, France., Guinot V; Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1011-EGID, Lille, France., Barreby E; Center for Infectious Medicine (CIM), Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden., Esser N; Laboratory of Immunometabolism and Nutrition, GIGA-I3, University of Liège, Liège, Belgium.; Division of Diabetes, Nutrition and Metabolic Disorders, Department of Medicine, CHU Liège, Liège, Belgium., Caiazzo R; Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1190-EGID (Translational research in Diabetes), Lille, France., Verkindt H; Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1190-EGID (Translational research in Diabetes), Lille, France., Legendre B; Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1190-EGID (Translational research in Diabetes), Lille, France., Raverdy V; Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1190-EGID (Translational research in Diabetes), Lille, France., Cheval L; Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, Université Paris Cité, Laboratoire de Physiologie Rénale et Tubulopathies, Paris, France.; CNRS EMR 8228-Unité Métabolisme et Physiologie Rénale, Paris, France., Paquot N; Laboratory of Immunometabolism and Nutrition, GIGA-I3, University of Liège, Liège, Belgium.; Division of Diabetes, Nutrition and Metabolic Disorders, Department of Medicine, CHU Liège, Liège, Belgium., Piette J; Laboratory of Virology and Immunology, GIGA-Signal Transduction, University of Liège, Liège, Belgium., Legrand-Poels S; Laboratory of Immunometabolism and Nutrition, GIGA-I3, University of Liège, Liège, Belgium., Aouadi M; Center for Infectious Medicine (CIM), Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden., Pattou F; Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1190-EGID (Translational research in Diabetes), Lille, France., Staels B; Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1011-EGID, Lille, France., Dombrowicz D; Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1011-EGID, Lille, France. david.dombrowicz@pasteur-lille.fr.

المصدر: Nature communications [Nat Commun] 2024 Aug 21; Vol. 15 (1), pp. 7173. Date of Electronic Publication: 2024 Aug 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Growth Differentiation Factor 15*/metabolism , Growth Differentiation Factor 15*/genetics , Obesity*/metabolism , Obesity*/pathology , Hepatocytes*/metabolism , Macrophages*/metabolism , Adipose Tissue*/metabolism , Diabetes Mellitus, Type 2*/metabolism , Diabetes Mellitus, Type 2*/pathology , Fatty Liver*/metabolism , Fatty Liver*/pathology, Animals ; Male ; Mice ; Humans ; Mice, Inbred C57BL ; Liver/metabolism ; Liver/pathology ; Disease Models, Animal ; Signal Transduction

المؤلفون: Clavreul L; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Boulevard du Professeur Jules Leclercq, 59045 Lille, France., Bernard L; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Boulevard du Professeur Jules Leclercq, 59045 Lille, France., Cotte AK; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Boulevard du Professeur Jules Leclercq, 59045 Lille, France., Hennuyer N; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Boulevard du Professeur Jules Leclercq, 59045 Lille, France., Bourouh C; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Boulevard du Professeur Jules Leclercq, 59045 Lille, France., Devos C; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Boulevard du Professeur Jules Leclercq, 59045 Lille, France., Helleboid A; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Boulevard du Professeur Jules Leclercq, 59045 Lille, France., Haas JT; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Boulevard du Professeur Jules Leclercq, 59045 Lille, France., Verrijken A; Laboratory of Experimental Medicine and Paediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, 1 B-2610 Antwerp, Belgium; Department of Endocrinology, Diabetology and Metabolism, Antwerp University Hospital, 1 B-2610 Antwerp, Belgium., Gheeraert C; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Boulevard du Professeur Jules Leclercq, 59045 Lille, France., Derudas B; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Boulevard du Professeur Jules Leclercq, 59045 Lille, France., Guille L; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Boulevard du Professeur Jules Leclercq, 59045 Lille, France., Chevalier J; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Boulevard du Professeur Jules Leclercq, 59045 Lille, France., Eeckhoute J; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Boulevard du Professeur Jules Leclercq, 59045 Lille, France., Vallez E; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Boulevard du Professeur Jules Leclercq, 59045 Lille, France., Dorchies E; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Boulevard du Professeur Jules Leclercq, 59045 Lille, France., Van Gaal L; Laboratory of Experimental Medicine and Paediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, 1 B-2610 Antwerp, Belgium; Department of Endocrinology, Diabetology and Metabolism, Antwerp University Hospital, 1 B-2610 Antwerp, Belgium., Lassailly G; Univ. Lille, Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, 1 place de Verdun, 59000 Lille, France., Francque S; Laboratory of Experimental Medicine and Paediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, 1 B-2610 Antwerp, Belgium; Department of Gastroenterology and Hepatology, Antwerp University Hospital, 1 B-2610 Antwerp, Belgium; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Germany., Staels B; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Boulevard du Professeur Jules Leclercq, 59045 Lille, France., Paumelle R; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011, EGID, Boulevard du Professeur Jules Leclercq, 59045 Lille, France. Electronic address: rejane.lestrelin@univ-lille.fr.

المصدر: Metabolism: clinical and experimental [Metabolism] 2024 Feb; Vol. 151, pp. 155720. Date of Electronic Publication: 2023 Nov 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 0375267 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8600 (Electronic) Linking ISSN: 00260495 NLM ISO Abbreviation: Metabolism Subsets: MEDLINE

مواضيع طبية MeSH: Fatty Liver*/metabolism , Metabolic Diseases*/metabolism, Animals ; Humans ; Mice ; Disease Progression ; Fatty Acids/metabolism ; Lipid Metabolism/genetics ; Liver/metabolism ; PPAR alpha/metabolism ; Ubiquitin/metabolism ; Ubiquitins/metabolism

المؤلفون: Heumel S; Univ. Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 9017 - CIIL - Center for Infection and Immunity of Lille, Lille, France., de Rezende Rodovalho V; Laboratory of Immunoinflammation, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Urien C; Genoscreen, Lille, France., Specque F; Biomathematica, Rue des Aloes, Quartier Balestrino, Ajaccio, France., Brito Rodrigues P; Univ. Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 9017 - CIIL - Center for Infection and Immunity of Lille, Lille, France.; Laboratory of Immunoinflammation, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Robil C; Univ. Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 9017 - CIIL - Center for Infection and Immunity of Lille, Lille, France., Delval L; Univ. Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 9017 - CIIL - Center for Infection and Immunity of Lille, Lille, France., Sencio V; Univ. Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 9017 - CIIL - Center for Infection and Immunity of Lille, Lille, France., Descat A; Univ. Lille, CHU Lille, EA 7365 - GRITA - Groupe de Recherche sur les formes Injectables et les Technologies Associées, Lille, France., Deruyter L; Univ. Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 9017 - CIIL - Center for Infection and Immunity of Lille, Lille, France., Ferreira S; Genoscreen, Lille, France., Gomes Machado M; Univ. Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 9017 - CIIL - Center for Infection and Immunity of Lille, Lille, France., Barthelemy A; Univ. Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 9017 - CIIL - Center for Infection and Immunity of Lille, Lille, France., Angulo FS; Univ. Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 9017 - CIIL - Center for Infection and Immunity of Lille, Lille, France., Haas JT; Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, Lille, France., Goosens JF; Univ. Lille, CHU Lille, EA 7365 - GRITA - Groupe de Recherche sur les formes Injectables et les Technologies Associées, Lille, France., Wolowczuk I; Univ. Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 9017 - CIIL - Center for Infection and Immunity of Lille, Lille, France., Grangette C; Univ. Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 9017 - CIIL - Center for Infection and Immunity of Lille, Lille, France., Rouillé Y; Univ. Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 9017 - CIIL - Center for Infection and Immunity of Lille, Lille, France., Grimaud G; Biomathematica, Rue des Aloes, Quartier Balestrino, Ajaccio, France., Lenski M; Univ. Lrille, CHU Lille, Service de toxicologie et Génopathies, ULR 4483 - IMPECS - IMPact de l'Environnement Chimique sur la Santé humaine, Lille, France., Hennart B; Univ. Lrille, CHU Lille, Service de toxicologie et Génopathies, ULR 4483 - IMPECS - IMPact de l'Environnement Chimique sur la Santé humaine, Lille, France., Ramirez Vinolo MA; Laboratory of Immunoinflammation, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Trottein F; Univ. Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 9017 - CIIL - Center for Infection and Immunity of Lille, Lille, France.

المصدر: Gut microbes [Gut Microbes] 2024 Jan-Dec; Vol. 16 (1), pp. 2325067. Date of Electronic Publication: 2024 Mar 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE

مواضيع طبية MeSH: Influenza, Human* , Gastrointestinal Microbiome* , Actinobacteria*, Humans ; Animals ; Mice ; Propionates ; Tryptophan ; Inflammation ; Polyamines

المؤلفون: Johanns M; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR1011-EGID, F-59000 Lille, France., Haas JT; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR1011-EGID, F-59000 Lille, France., Raverdy V; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR1190-EGID, F-59000 Lille, France., Vandel J; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR1011-EGID, F-59000 Lille, France., Chevalier-Dubois J; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR1011-EGID, F-59000 Lille, France., Guille L; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR1011-EGID, F-59000 Lille, France., Derudas B; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR1011-EGID, F-59000 Lille, France., Legendre B; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR1190-EGID, F-59000 Lille, France., Caiazzo R; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR1190-EGID, F-59000 Lille, France., Verkindt H; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR1190-EGID, F-59000 Lille, France., Gnemmi V; Univ. Lille, Inserm, CHU Lille, UMR 1172, Lille, France., Leteurtre E; Univ. Lille, Inserm, CHU Lille, UMR 1172, Lille, France., Derhourhi M; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR 1283/8199-EGID, F-59000 Lille, France., Bonnefond A; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR 1283/8199-EGID, F-59000 Lille, France.; Department of Metabolism, Imperial College London; London, United Kingdom., Froguel P; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR 1283/8199-EGID, F-59000 Lille, France.; Department of Metabolism, Imperial College London; London, United Kingdom., Eeckhoute J; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR1011-EGID, F-59000 Lille, France., Lassailly G; Univ. Lille, Inserm, CHU Lille, UMR 995-LIRIC, Lille, France., Mathurin P; Univ. Lille, Inserm, CHU Lille, UMR 995-LIRIC, Lille, France., Pattou F; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR1190-EGID, F-59000 Lille, France., Staels B; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR1011-EGID, F-59000 Lille, France., Lefebvre P; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR1011-EGID, F-59000 Lille, France.

المصدر: JHEP reports : innovation in hepatology [JHEP Rep] 2023 Oct 27; Vol. 6 (1), pp. 100948. Date of Electronic Publication: 2023 Oct 27 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101761237 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-5559 (Electronic) Linking ISSN: 25895559 NLM ISO Abbreviation: JHEP Rep Subsets: PubMed not MEDLINE

المؤلفون: Lalloyer F; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000, Lille, France., Mogilenko DA; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000, Lille, France; Department of Medicine, Department of Pathology, Microbiology and Immunology, Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Verrijken A; Laboratory of Experimental Medicine and Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, 2610, Wilrijk, Antwerp, Belgium; Department of Endocrinology, Diabetology and Metabolism, Antwerp University Hospital, 2650, Edegem, Antwerp, Belgium., Haas JT; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000, Lille, France., Lamazière A; Centre de Recherche Saint-Antoine, CRSA, AP-HP, Hôpital Saint Antoine, Clinical Metabolomic Department, Sorbonne Université, Inserm, F-75012, Paris, France., Kouach M; University of Lille, CHU Lille, EA 7365-GRITA-Groupe de Recherche sur les formes Injectables et les Technologies Associées, F-59000, Lille, France., Descat A; University of Lille, CHU Lille, EA 7365-GRITA-Groupe de Recherche sur les formes Injectables et les Technologies Associées, F-59000, Lille, France., Caron S; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000, Lille, France., Vallez E; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000, Lille, France., Derudas B; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000, Lille, France., Gheeraert C; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000, Lille, France., Baugé E; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000, Lille, France., Despres G; Centre de Recherche Saint-Antoine, CRSA, AP-HP, Hôpital Saint Antoine, Clinical Metabolomic Department, Sorbonne Université, Inserm, F-75012, Paris, France., Dirinck E; Laboratory of Experimental Medicine and Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, 2610, Wilrijk, Antwerp, Belgium; Department of Endocrinology, Diabetology and Metabolism, Antwerp University Hospital, 2650, Edegem, Antwerp, Belgium., Tailleux A; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000, Lille, France., Dombrowicz D; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000, Lille, France., Van Gaal L; Laboratory of Experimental Medicine and Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, 2610, Wilrijk, Antwerp, Belgium; Department of Endocrinology, Diabetology and Metabolism, Antwerp University Hospital, 2650, Edegem, Antwerp, Belgium., Eeckhoute J; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000, Lille, France., Lefebvre P; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000, Lille, France., Goossens JF; University of Lille, CHU Lille, EA 7365-GRITA-Groupe de Recherche sur les formes Injectables et les Technologies Associées, F-59000, Lille, France., Francque S; Laboratory of Experimental Medicine and Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, 2610, Wilrijk, Antwerp, Belgium; Department of Gastroenterology and Hepatology, Antwerp University Hospital, ERN RARE-LIVER, 2650, Edegem, Antwerp, Belgium., Staels B; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, F-59000, Lille, France. Electronic address: bart.staels@pasteur-lille.fr.

المصدر: Journal of hepatology [J Hepatol] 2023 Oct; Vol. 79 (4), pp. 898-909. Date of Electronic Publication: 2023 May 23.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE

مواضيع طبية MeSH: Gastric Bypass*/methods , Non-alcoholic Fatty Liver Disease*/genetics , Non-alcoholic Fatty Liver Disease*/surgery , Obesity, Morbid*/complications, Humans ; Transcriptome ; Obesity/complications ; Cholesterol ; Homeostasis ; Inflammation/complications

المؤلفون: Deprince A; Univ. Lille , Inserm , CHU Lille , Institut Pasteur de Lille , U1011- EGID , Lille , France., Hennuyer N; Univ. Lille , Inserm , CHU Lille , Institut Pasteur de Lille , U1011- EGID , Lille , France., Kooijman S; Division of Endocrinology, and Einthoven Laboratory for Experimental Vascular Medicine , Department of Medicine , Leiden University Medical Center , Leiden , The Netherlands., Pronk ACM; Division of Endocrinology, and Einthoven Laboratory for Experimental Vascular Medicine , Department of Medicine , Leiden University Medical Center , Leiden , The Netherlands., Baugé E; Univ. Lille , Inserm , CHU Lille , Institut Pasteur de Lille , U1011- EGID , Lille , France., Lienard V; Univ. Lille , Inserm , CHU Lille , Institut Pasteur de Lille , U1011- EGID , Lille , France., Verrijken A; Department of Endocrinology, Diabetology and Metabolism , Antwerp University Hospital , Antwerp , Belgium.; Laboratory of Experimental Medicine and Paediatrics , University of Antwerp , Antwerp , Belgium., Dirinck E; Department of Endocrinology, Diabetology and Metabolism , Antwerp University Hospital , Antwerp , Belgium.; Laboratory of Experimental Medicine and Paediatrics , University of Antwerp , Antwerp , Belgium., Vonghia L; Department of Gastroenterology Hepatology , Antwerp University Hospital , Antwerp , Belgium.; Laboratory of Experimental Medicine and Paediatrics , University of Antwerp , Antwerp , Belgium., Woitrain E; Univ. Lille , Inserm , CHU Lille , Institut Pasteur de Lille , U1011- EGID , Lille , France., Kloosterhuis NJ; Department of Paediatrics , University of Groningen , University Medical Center Groningen , Groningen , The Netherlands., Marez E; Univ. Lille , Inserm , CHU Lille , Institut Pasteur de Lille , U1011- EGID , Lille , France., Jacquemain P; Univ. Lille , Inserm , CHU Lille , Institut Pasteur de Lille , U1011- EGID , Lille , France., Wolters JC; Department of Paediatrics , University of Groningen , University Medical Center Groningen , Groningen , The Netherlands., Lalloyer F; Univ. Lille , Inserm , CHU Lille , Institut Pasteur de Lille , U1011- EGID , Lille , France., Eberlé D; Univ. Lille , Inserm , CHU Lille , Institut Pasteur de Lille , U1011- EGID , Lille , France., Quemener S; Univ. Lille , Inserm , CHU Lille , Institut Pasteur de Lille , U1011- EGID , Lille , France., Vallez E; Univ. Lille , Inserm , CHU Lille , Institut Pasteur de Lille , U1011- EGID , Lille , France., Tailleux A; Univ. Lille , Inserm , CHU Lille , Institut Pasteur de Lille , U1011- EGID , Lille , France., Kouach M; Univ. Lille , CHU Lille , ULR 7365-GRITA-Groupe de Recherche sur les formes Injectables et les Technologies Associées , Lille , France., Goossens JF; Univ. Lille , CHU Lille , ULR 7365-GRITA-Groupe de Recherche sur les formes Injectables et les Technologies Associées , Lille , France., Raverdy V; Univ. Lille , Inserm, CHU Lille, Institut Pasteur de Lille , U1190 - EGID , Lille , France., Derudas B; Univ. Lille , Inserm , CHU Lille , Institut Pasteur de Lille , U1011- EGID , Lille , France., Kuivenhoven JA; Department of Paediatrics , University of Groningen , University Medical Center Groningen , Groningen , The Netherlands., Croyal M; Université de Nantes , CNRS, INSERM, l'institut du thorax , Nantes , France.; Université de Nantes , CHU Nantes, Inserm, CNRS, SFR Santé, Inserm UMS 016 , CNRS UMS 3556 , Nantes , France.; CRNH-Ouest Mass Spectrometry Core Facility , Nantes , France., van de Sluis B; Department of Paediatrics , University of Groningen , University Medical Center Groningen , Groningen , The Netherlands., Francque S; Department of Gastroenterology Hepatology , Antwerp University Hospital , Antwerp , Belgium.; Laboratory of Experimental Medicine and Paediatrics , University of Antwerp , Antwerp , Belgium., Pattou F; Univ. Lille , Inserm, CHU Lille, Institut Pasteur de Lille , U1190 - EGID , Lille , France., Rensen PCN; Division of Endocrinology, and Einthoven Laboratory for Experimental Vascular Medicine , Department of Medicine , Leiden University Medical Center , Leiden , The Netherlands., Staels B; Univ. Lille , Inserm , CHU Lille , Institut Pasteur de Lille , U1011- EGID , Lille , France., Haas JT; Univ. Lille , Inserm , CHU Lille , Institut Pasteur de Lille , U1011- EGID , Lille , France.

المصدر: Hepatology (Baltimore, Md.) [Hepatology] 2023 Apr 01; Vol. 77 (4), pp. 1287-1302. Date of Electronic Publication: 2022 Jul 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3350 (Electronic) Linking ISSN: 02709139 NLM ISO Abbreviation: Hepatology Subsets: MEDLINE

مواضيع طبية MeSH: Non-alcoholic Fatty Liver Disease*/genetics , Non-alcoholic Fatty Liver Disease*/metabolism, Mice ; Animals ; Humans ; Lipoproteins/metabolism ; Apolipoproteins/metabolism ; Apolipoproteins/pharmacology ; Triglycerides/metabolism ; Liver/metabolism ; Lipoproteins, VLDL/metabolism

المؤلفون: Bobowski-Gerard M; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Boulet C; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Zummo FP; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Dubois-Chevalier J; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Gheeraert C; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Bou Saleh M; Univ. Lille, Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, F-59000, Lille, France., Strub JM; Laboratoire de Spectrométrie de Masse BioOrganique, CNRS UMR7178, Univ Strasbourg, IPHC, Infrastructure Nationale de Protéomique ProFI - FR2048, 67087, Strasbourg, France., Farce A; Univ. Lille, Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, F-59000, Lille, France., Ploton M; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Guille L; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Vandel J; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Bongiovanni A; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41 - UAR 2014 - PLBS, F-59000, Lille, France., Very N; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Woitrain E; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Deprince A; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Lalloyer F; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Bauge E; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Ferri L; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Ntandja-Wandji LC; Univ. Lille, Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, F-59000, Lille, France., Cotte AK; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Grangette C; U1019-UMR 9017-CIIL-Centre d'Infection et d'Immunité de Lille, Institut Pasteur de Lille, Université de Lille, CNRS, Inserm, CHU Lille, F-59000, Lille, France., Vallez E; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Cianférani S; Laboratoire de Spectrométrie de Masse BioOrganique, CNRS UMR7178, Univ Strasbourg, IPHC, Infrastructure Nationale de Protéomique ProFI - FR2048, 67087, Strasbourg, France., Raverdy V; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1190-EGID, Translational Research in Diabetes, Lille, France., Caiazzo R; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1190-EGID, Translational Research in Diabetes, Lille, France., Gnemmi V; Service d'anatomopathologie, Centre Hospitalier Universitaire de Lille, Université de Lille, INSERM UMR-S 1172, Lille, France., Leteurtre E; Service d'anatomopathologie, Centre Hospitalier Universitaire de Lille, Université de Lille, INSERM UMR-S 1172, Lille, France., Pourcet B; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Paumelle R; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Ravnskjaer K; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, 5230, Denmark.; Center for Functional Genomics and Tissue Plasticity (ATLAS), University of Southern Denmark, Odense, 5230, Denmark., Lassailly G; Univ. Lille, Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, F-59000, Lille, France., Haas JT; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Mathurin P; Univ. Lille, Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, F-59000, Lille, France., Pattou F; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1190-EGID, Translational Research in Diabetes, Lille, France., Dubuquoy L; Univ. Lille, Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, F-59000, Lille, France., Staels B; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Lefebvre P; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France., Eeckhoute J; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000, Lille, France. jerome.eeckhoute@inserm.fr.

المصدر: Nature communications [Nat Commun] 2022 Sep 10; Vol. 13 (1), pp. 5324. Date of Electronic Publication: 2022 Sep 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Liver Cirrhosis*/genetics , Liver Cirrhosis*/metabolism , Myofibroblasts*/metabolism, Animals ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Genomics ; Humans ; Mice ; Transcription Factors/genetics ; Transcription Factors/metabolism

المؤلفون: Fougeray T; Toxalim (Research Center in Food Toxicology), INRAE, ENVT, INP- PURPAN, UMR 1331, UPS, Université de Toulouse, 180 Chemin de Tournefeuille, 31027 Toulouse, France; Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), UMR1297, INSERM/UPS, Université de Toulouse, 1 Avenue Jean Poulhès, BP 84225, 31432 Toulouse, France., Polizzi A; Toxalim (Research Center in Food Toxicology), INRAE, ENVT, INP- PURPAN, UMR 1331, UPS, Université de Toulouse, 180 Chemin de Tournefeuille, 31027 Toulouse, France., Régnier M; Toxalim (Research Center in Food Toxicology), INRAE, ENVT, INP- PURPAN, UMR 1331, UPS, Université de Toulouse, 180 Chemin de Tournefeuille, 31027 Toulouse, France., Fougerat A; Toxalim (Research Center in Food Toxicology), INRAE, ENVT, INP- PURPAN, UMR 1331, UPS, Université de Toulouse, 180 Chemin de Tournefeuille, 31027 Toulouse, France., Ellero-Simatos S; Toxalim (Research Center in Food Toxicology), INRAE, ENVT, INP- PURPAN, UMR 1331, UPS, Université de Toulouse, 180 Chemin de Tournefeuille, 31027 Toulouse, France., Lippi Y; Toxalim (Research Center in Food Toxicology), INRAE, ENVT, INP- PURPAN, UMR 1331, UPS, Université de Toulouse, 180 Chemin de Tournefeuille, 31027 Toulouse, France., Smati S; Toxalim (Research Center in Food Toxicology), INRAE, ENVT, INP- PURPAN, UMR 1331, UPS, Université de Toulouse, 180 Chemin de Tournefeuille, 31027 Toulouse, France; Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), UMR1297, INSERM/UPS, Université de Toulouse, 1 Avenue Jean Poulhès, BP 84225, 31432 Toulouse, France; Université de Nantes, INSERM, CNRS, CHU Nantes, Institut du Thorax, 44000 Nantes, France., Lasserre F; Toxalim (Research Center in Food Toxicology), INRAE, ENVT, INP- PURPAN, UMR 1331, UPS, Université de Toulouse, 180 Chemin de Tournefeuille, 31027 Toulouse, France., Tramunt B; Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), UMR1297, INSERM/UPS, Université de Toulouse, 1 Avenue Jean Poulhès, BP 84225, 31432 Toulouse, France; Service de Diabétologie, Maladies Métaboliques et Nutrition, CHU de Toulouse, Université de Toulouse, Toulouse, France., Huillet M; Toxalim (Research Center in Food Toxicology), INRAE, ENVT, INP- PURPAN, UMR 1331, UPS, Université de Toulouse, 180 Chemin de Tournefeuille, 31027 Toulouse, France., Dopavogui L; Toxalim (Research Center in Food Toxicology), INRAE, ENVT, INP- PURPAN, UMR 1331, UPS, Université de Toulouse, 180 Chemin de Tournefeuille, 31027 Toulouse, France., Salvi J; Centre des Sciences du Goût et de l'Alimentation, CNRS, INRAE, Université Bourgogne Franche-Comté, Institut Agro Dijon, 21000 Dijon, France., Nédélec E; Centre des Sciences du Goût et de l'Alimentation, CNRS, INRAE, Université Bourgogne Franche-Comté, Institut Agro Dijon, 21000 Dijon, France., Gigot V; Centre des Sciences du Goût et de l'Alimentation, CNRS, INRAE, Université Bourgogne Franche-Comté, Institut Agro Dijon, 21000 Dijon, France., Smith L; Toxalim (Research Center in Food Toxicology), INRAE, ENVT, INP- PURPAN, UMR 1331, UPS, Université de Toulouse, 180 Chemin de Tournefeuille, 31027 Toulouse, France., Naylies C; Toxalim (Research Center in Food Toxicology), INRAE, ENVT, INP- PURPAN, UMR 1331, UPS, Université de Toulouse, 180 Chemin de Tournefeuille, 31027 Toulouse, France., Sommer C; Toxalim (Research Center in Food Toxicology), INRAE, ENVT, INP- PURPAN, UMR 1331, UPS, Université de Toulouse, 180 Chemin de Tournefeuille, 31027 Toulouse, France., Haas JT; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000 Lille, France., Wahli W; Toxalim (Research Center in Food Toxicology), INRAE, ENVT, INP- PURPAN, UMR 1331, UPS, Université de Toulouse, 180 Chemin de Tournefeuille, 31027 Toulouse, France; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore 308232, Singapore; Center for Integrative Genomics, University of Lausanne, Le Génopode, 1015 Lausanne, Switzerland., Duez H; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, F-59000 Lille, France., Gourdy P; Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), UMR1297, INSERM/UPS, Université de Toulouse, 1 Avenue Jean Poulhès, BP 84225, 31432 Toulouse, France; Service de Diabétologie, Maladies Métaboliques et Nutrition, CHU de Toulouse, Université de Toulouse, Toulouse, France., Gamet-Payrastre L; Toxalim (Research Center in Food Toxicology), INRAE, ENVT, INP- PURPAN, UMR 1331, UPS, Université de Toulouse, 180 Chemin de Tournefeuille, 31027 Toulouse, France., Benani A; Centre des Sciences du Goût et de l'Alimentation, CNRS, INRAE, Université Bourgogne Franche-Comté, Institut Agro Dijon, 21000 Dijon, France., Burnol AF; Université de Paris, Institut Cochin, CNRS, INSERM, 75014 Paris, France., Loiseau N; Toxalim (Research Center in Food Toxicology), INRAE, ENVT, INP- PURPAN, UMR 1331, UPS, Université de Toulouse, 180 Chemin de Tournefeuille, 31027 Toulouse, France., Postic C; Université de Paris, Institut Cochin, CNRS, INSERM, 75014 Paris, France., Montagner A; Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), UMR1297, INSERM/UPS, Université de Toulouse, 1 Avenue Jean Poulhès, BP 84225, 31432 Toulouse, France. Electronic address: alexandra.montagner@inserm.fr., Guillou H; Toxalim (Research Center in Food Toxicology), INRAE, ENVT, INP- PURPAN, UMR 1331, UPS, Université de Toulouse, 180 Chemin de Tournefeuille, 31027 Toulouse, France. Electronic address: herve.guillou@inrae.fr.

المصدر: Cell reports [Cell Rep] 2022 Apr 12; Vol. 39 (2), pp. 110674.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: ARNTL Transcription Factors*/genetics , ARNTL Transcription Factors*/metabolism , Circadian Clocks*/genetics, Animals ; CLOCK Proteins/genetics ; CLOCK Proteins/metabolism ; Circadian Rhythm/genetics ; Gene Expression ; Gene Expression Regulation ; Hepatocytes/metabolism ; Insulin/metabolism ; Liver/metabolism ; Mice ; Receptor, Insulin/genetics ; Receptor, Insulin/metabolism

المؤلفون: Zanoni P; Institute for Clinical Chemistry, University and University Hospital Zurich, Switzerland (P.Z., G.P., J.R., S.V., M.Y., M.K., S.R., L.R., A.v.E.).; Now with Institute of Medical Genetics, University of Zurich, Switzerland (P.Z.).; Center for Integrative Human Physiology, University of Zurich, Switzerland (P.Z., G.P., S.V., M.Y., M.K., S.R., L.R., A.v.E.)., Panteloglou G; Institute for Clinical Chemistry, University and University Hospital Zurich, Switzerland (P.Z., G.P., J.R., S.V., M.Y., M.K., S.R., L.R., A.v.E.).; Center for Integrative Human Physiology, University of Zurich, Switzerland (P.Z., G.P., S.V., M.Y., M.K., S.R., L.R., A.v.E.)., Othman A; Institute of Molecular Systems Biology, ETH Zurich, Switzerland (A.O.)., Haas JT; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, France (J.T.H., B.S.)., Meier R; Scientific center for optical and electron microscopy (ScopeM), ETH Zurich, Switzerland (R.M., S.F.N., A.J.R., S.S., M. Stebler)., Rimbert A; Department of Pediatrics, Section Molecular Genetics, University of Groningen, University Medical Center Groningen, the Netherlands (A.R., M.W., J.C.W., N.C.A.H., M. Smit, B.v.d.S., J.A.K.).; Now with Inserm UMR 1087/CNRS UMR 6291 IRS-UN, Nantes, France (A.R.)., Futema M; Cardiology Research Centre, Molecular and Clinical Sciences Research Institute, St George's, University of London, United Kingdom (M.F.)., Abou Khalil Y; LVTS-INSERM UMRS 1148 and University of Paris, CHU Xavier Bichat, Paris, France (Y.A.K., J.-P.R., C.B., M. Varret).; Laboratory of Biochemistry and Molecular Therapeutics (LBTM), Faculty of Pharmacy and Pôle technologie Santé (PTS), Saint-Joseph University, Beirut, Lebanon (Y.A.K.)., Norrelykke SF; Scientific center for optical and electron microscopy (ScopeM), ETH Zurich, Switzerland (R.M., S.F.N., A.J.R., S.S., M. Stebler)., Rzepiela AJ; Scientific center for optical and electron microscopy (ScopeM), ETH Zurich, Switzerland (R.M., S.F.N., A.J.R., S.S., M. Stebler)., Stoma S; Scientific center for optical and electron microscopy (ScopeM), ETH Zurich, Switzerland (R.M., S.F.N., A.J.R., S.S., M. Stebler)., Stebler M; Scientific center for optical and electron microscopy (ScopeM), ETH Zurich, Switzerland (R.M., S.F.N., A.J.R., S.S., M. Stebler)., van Dijk F; Department of Genetics, University of Groningen, University Medical Center Groningen, the Netherlands (F.v.D., A.v.d.G.)., Wijers M; Department of Pediatrics, Section Molecular Genetics, University of Groningen, University Medical Center Groningen, the Netherlands (A.R., M.W., J.C.W., N.C.A.H., M. Smit, B.v.d.S., J.A.K.)., Wolters JC; Department of Pediatrics, Section Molecular Genetics, University of Groningen, University Medical Center Groningen, the Netherlands (A.R., M.W., J.C.W., N.C.A.H., M. Smit, B.v.d.S., J.A.K.)., Dalila N; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (N.D., A.T.-H.)., Huijkman NCA; Department of Pediatrics, Section Molecular Genetics, University of Groningen, University Medical Center Groningen, the Netherlands (A.R., M.W., J.C.W., N.C.A.H., M. Smit, B.v.d.S., J.A.K.)., Smit M; Department of Pediatrics, Section Molecular Genetics, University of Groningen, University Medical Center Groningen, the Netherlands (A.R., M.W., J.C.W., N.C.A.H., M. Smit, B.v.d.S., J.A.K.)., Gallo A; AP-HP, Endocrinology and Metabolism Department, Human Research Nutrition Center, Pitié-Salpêtrière Hospital, Paris, France (A. Gallo, V.C.)., Carreau V; AP-HP, Endocrinology and Metabolism Department, Human Research Nutrition Center, Pitié-Salpêtrière Hospital, Paris, France (A. Gallo, V.C.)., Philippi A; Université de Paris, Faculté de Médecine Paris-Diderot, UMR-S958 Paris, France; Now with Université de Paris, Institut Cochin, INSERM U1016, CNRS UMR-8104, Paris, France (A.P.)., Rabès JP; LVTS-INSERM UMRS 1148 and University of Paris, CHU Xavier Bichat, Paris, France (Y.A.K., J.-P.R., C.B., M. Varret).; AP-HP, Université Paris-Saclay, Paris, France (J.-P.R.).; UFR Simone Veil des Sciences de la Santé, UVSQ, Montigny-Le-Bretonneux, France (J.-P.R.)., Boileau C; LVTS-INSERM UMRS 1148 and University of Paris, CHU Xavier Bichat, Paris, France (Y.A.K., J.-P.R., C.B., M. Varret).; AP-HP, Genetics Department, CHU Xavier Bichat, Université de Paris, France (C.B.)., Visentin M; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, Switzerland (M. Visentin)., Vonghia L; Department of Gastroenterology and Hepatology, Antwerp University Hospital, Edegem, Belgium (L.V., J.W., S.F.).; Laboratory of Experimental Medicine and Paediatrics, Faculty of Medicine, University of Antwerp, Belgium (L.V., J.W., S.F., A. Verrijken, A. Verhaegen, L.V.G.)., Weyler J; Department of Gastroenterology and Hepatology, Antwerp University Hospital, Edegem, Belgium (L.V., J.W., S.F.)., Francque S; Department of Gastroenterology and Hepatology, Antwerp University Hospital, Edegem, Belgium (L.V., J.W., S.F.).; Laboratory of Experimental Medicine and Paediatrics, Faculty of Medicine, University of Antwerp, Belgium (L.V., J.W., S.F., A. Verrijken, A. Verhaegen, L.V.G.)., Verrijken A; Laboratory of Experimental Medicine and Paediatrics, Faculty of Medicine, University of Antwerp, Belgium (L.V., J.W., S.F., A. Verrijken, A. Verhaegen, L.V.G.).; Department of Endocrinology, Diabetology and Metabolism, Antwerp University Hospital, Edegem, Belgium (A. Verrijken, A. Verhaegen, L.V.G.)., Verhaegen A; Laboratory of Experimental Medicine and Paediatrics, Faculty of Medicine, University of Antwerp, Belgium (L.V., J.W., S.F., A. Verrijken, A. Verhaegen, L.V.G.).; Department of Endocrinology, Diabetology and Metabolism, Antwerp University Hospital, Edegem, Belgium (A. Verrijken, A. Verhaegen, L.V.G.)., Van Gaal L; Laboratory of Experimental Medicine and Paediatrics, Faculty of Medicine, University of Antwerp, Belgium (L.V., J.W., S.F., A. Verrijken, A. Verhaegen, L.V.G.).; Department of Endocrinology, Diabetology and Metabolism, Antwerp University Hospital, Edegem, Belgium (A. Verrijken, A. Verhaegen, L.V.G.)., van der Graaf A; Department of Genetics, University of Groningen, University Medical Center Groningen, the Netherlands (F.v.D., A.v.d.G.)., van Rosmalen BV; Department of Surgery, Academic Medical Center, University of Amsterdam, the Netherlands (B.V.v.R.)., Robert J; Institute for Clinical Chemistry, University and University Hospital Zurich, Switzerland (P.Z., G.P., J.R., S.V., M.Y., M.K., S.R., L.R., A.v.E.)., Velagapudi S; Institute for Clinical Chemistry, University and University Hospital Zurich, Switzerland (P.Z., G.P., J.R., S.V., M.Y., M.K., S.R., L.R., A.v.E.).; Center for Molecular Cardiology, University of Zurich, Switzerland (S.V.).; Center for Integrative Human Physiology, University of Zurich, Switzerland (P.Z., G.P., S.V., M.Y., M.K., S.R., L.R., A.v.E.)., Yalcinkaya M; Institute for Clinical Chemistry, University and University Hospital Zurich, Switzerland (P.Z., G.P., J.R., S.V., M.Y., M.K., S.R., L.R., A.v.E.).; Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY (M.Y.).; Center for Integrative Human Physiology, University of Zurich, Switzerland (P.Z., G.P., S.V., M.Y., M.K., S.R., L.R., A.v.E.)., Keel M; Institute for Clinical Chemistry, University and University Hospital Zurich, Switzerland (P.Z., G.P., J.R., S.V., M.Y., M.K., S.R., L.R., A.v.E.).; Center for Integrative Human Physiology, University of Zurich, Switzerland (P.Z., G.P., S.V., M.Y., M.K., S.R., L.R., A.v.E.)., Radosavljevic S; Institute for Clinical Chemistry, University and University Hospital Zurich, Switzerland (P.Z., G.P., J.R., S.V., M.Y., M.K., S.R., L.R., A.v.E.).; Center for Integrative Human Physiology, University of Zurich, Switzerland (P.Z., G.P., S.V., M.Y., M.K., S.R., L.R., A.v.E.)., Geier A; Division of Hepatology, Department of Medicine II, University Hospital Würzburg, Germany (A. Geier)., Tybjaerg-Hansen A; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (N.D., A.T.-H.)., Varret M; LVTS-INSERM UMRS 1148 and University of Paris, CHU Xavier Bichat, Paris, France (Y.A.K., J.-P.R., C.B., M. Varret)., Rohrer L; Institute for Clinical Chemistry, University and University Hospital Zurich, Switzerland (P.Z., G.P., J.R., S.V., M.Y., M.K., S.R., L.R., A.v.E.).; Center for Integrative Human Physiology, University of Zurich, Switzerland (P.Z., G.P., S.V., M.Y., M.K., S.R., L.R., A.v.E.)., Humphries SE; Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, United Kingdom (S.E.H.)., Staels B; University of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011- EGID, France (J.T.H., B.S.)., van de Sluis B; Department of Pediatrics, Section Molecular Genetics, University of Groningen, University Medical Center Groningen, the Netherlands (A.R., M.W., J.C.W., N.C.A.H., M. Smit, B.v.d.S., J.A.K.)., Kuivenhoven JA; Department of Pediatrics, Section Molecular Genetics, University of Groningen, University Medical Center Groningen, the Netherlands (A.R., M.W., J.C.W., N.C.A.H., M. Smit, B.v.d.S., J.A.K.)., von Eckardstein A; Institute for Clinical Chemistry, University and University Hospital Zurich, Switzerland (P.Z., G.P., J.R., S.V., M.Y., M.K., S.R., L.R., A.v.E.).; Center for Integrative Human Physiology, University of Zurich, Switzerland (P.Z., G.P., S.V., M.Y., M.K., S.R., L.R., A.v.E.).

المصدر: Circulation research [Circ Res] 2022 Jan 07; Vol. 130 (1), pp. 80-95. Date of Electronic Publication: 2021 Nov 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4571 (Electronic) Linking ISSN: 00097330 NLM ISO Abbreviation: Circ Res Subsets: MEDLINE

مواضيع طبية MeSH: RNA Splicing*, Nuclear Proteins/*metabolism , Receptors, LDL/*genetics, Cholesterol/metabolism ; HEK293 Cells ; Hep G2 Cells ; Humans ; Lipoproteins, LDL/metabolism ; Liver/metabolism ; Mutation ; Nuclear Proteins/genetics ; Receptors, LDL/metabolism ; Spliceosomes/metabolism