المؤلفون: Boof ML; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Géhin M; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Voors-Pette C; QPS Netherlands BV, Groningen, The Netherlands., Hsin CH; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Sippel V; Department of Translational Biomarkers, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Strasser DS; Department of Translational Biomarkers, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Dingemanse J; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.

المصدر: British journal of clinical pharmacology [Br J Clin Pharmacol] 2024 Feb; Vol. 90 (2), pp. 588-599. Date of Electronic Publication: 2023 Nov 16.

نوع المنشور: Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Half-Life*, Adult ; Humans ; Male ; Female ; Dose-Response Relationship, Drug ; Area Under Curve ; Double-Blind Method ; Healthy Volunteers ; Administration, Oral

المؤلفون: Masato A; UK Dementia Research Institute at University College London, London, United Kingdom. Electronic address: a.masato@ucl.ac.uk., Bubacco L; Department of Biology, University of Padova, Padova, Italy; Centro Studi per la Neurodegenerazione (CESNE), University of Padova, Padova, Italy. Electronic address: luigi.bubacco@unipd.it.

المصدر: Neurobiology of disease [Neurobiol Dis] 2024 Jun 15; Vol. 196, pp. 106524. Date of Electronic Publication: 2024 May 04.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

مواضيع طبية MeSH: alpha-Synuclein*/metabolism, Humans ; Half-Life ; Animals ; Synucleinopathies/metabolism ; Synucleinopathies/pathology ; Parkinson Disease/metabolism ; Parkinson Disease/genetics ; Proteostasis/physiology ; Neurons/metabolism

المؤلفون: Zhang J; Department of Protein Science, KTH Royal Institute of Technology, Roslagstullsbacken 21, Stockholm 114 17, Sweden., Bodenko V; Research Centrum for Oncotheranostics, Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk 634050, Russia; Scientific and Educational Laboratory of Chemical and Pharmaceutical Research, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk 634050, Russia., Larkina M; Research Centrum for Oncotheranostics, Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk 634050, Russia; Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk 634050, Russia., Bezverkhniaia E; Research Centrum for Oncotheranostics, Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk 634050, Russia; Department of Medicinal Chemistry, Uppsala University, 751 23 Uppsala, Sweden., Xu T; Department of Medicinal Chemistry, Uppsala University, 751 23 Uppsala, Sweden., Liao Y; Department of Medicinal Chemistry, Uppsala University, 751 23 Uppsala, Sweden., Abouzayed A; Department of Medicinal Chemistry, Uppsala University, 751 23 Uppsala, Sweden., Plotnikov E; Research Centrum for Oncotheranostics, Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk 634050, Russia., Tretyakova M; Research Centrum for Oncotheranostics, Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk 634050, Russia., Yuldasheva F; Research Centrum for Oncotheranostics, Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk 634050, Russia., Belousov MV; Research Centrum for Oncotheranostics, Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk 634050, Russia; Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk 634050, Russia., Orlova A; Department of Medicinal Chemistry, Uppsala University, 751 23 Uppsala, Sweden., Tolmachev V; Department of Immunology, Genetics and Pathology, Uppsala University, 751 85 Uppsala, Sweden., Gräslund T; Department of Protein Science, KTH Royal Institute of Technology, Roslagstullsbacken 21, Stockholm 114 17, Sweden. Electronic address: torbjorn@kth.se., Vorobyeva A; Department of Immunology, Genetics and Pathology, Uppsala University, 751 85 Uppsala, Sweden. Electronic address: anzhelika.vorobyeva@igp.uu.se.

المصدر: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2024 Jun; Vol. 370, pp. 468-478. Date of Electronic Publication: 2024 May 08.

نوع المنشور: Journal Article; Comparative Study

بيانات الدورية: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE

مواضيع طبية MeSH: Receptor, ErbB-2*/metabolism , Peptides*/chemistry , Peptides*/pharmacokinetics , Peptides*/administration & dosage, Animals ; Half-Life ; Humans ; Cell Line, Tumor ; Female ; Mice, Nude ; Albumins/chemistry ; Recombinant Fusion Proteins/pharmacokinetics ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/administration & dosage ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/pharmacokinetics ; Antineoplastic Agents/chemistry ; Mice ; Neoplasms/drug therapy ; Neoplasms/metabolism ; Immunoconjugates/pharmacokinetics ; Immunoconjugates/chemistry ; Immunoconjugates/administration & dosage ; Mice, Inbred BALB C ; Tissue Distribution

المؤلفون: Ay C; Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria., Napolitano M; PROMISE Department, University of Palermo, Palermo, Italy., Hassoun A; Haemophilia Treatment Center, Simone Veil Hospital, GH Eaubonne-Montmorency, Eaubonne, France., Tomic R; CSL Behring, Milan, Italy., Martin C; CSL Behring, Paris, France., Seifert W; CSL Behring, Marburg, Germany., Pinachyan K; CSL Behring, Brussels, Belgium., Oldenburg J; Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Medical Faculty, University of Bonn, Bonn, Germany.

المصدر: Haemophilia : the official journal of the World Federation of Hemophilia [Haemophilia] 2024 May; Vol. 30 (3), pp. 577-588. Date of Electronic Publication: 2024 Mar 29.

نوع المنشور: Journal Article; Systematic Review; Review

بيانات الدورية: Publisher: Blackwell Science Country of Publication: England NLM ID: 9442916 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2516 (Electronic) Linking ISSN: 13518216 NLM ISO Abbreviation: Haemophilia Subsets: MEDLINE

مواضيع طبية MeSH: Factor VIII*/pharmacokinetics , Factor VIII*/therapeutic use , Hemophilia A*/drug therapy , Recombinant Proteins*/therapeutic use , Recombinant Proteins*/pharmacokinetics, Humans ; Half-Life

المؤلفون: Reddiar SB; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Australia., Abdallah M; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Australia., Styles IK; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Australia., Müllertz OO; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Trevaskis NL; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Australia. Electronic address: Natalie.Trevaskis@monash.edu.

المصدر: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2024 Jul; Vol. 200, pp. 114339. Date of Electronic Publication: 2024 May 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 9109778 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3441 (Electronic) Linking ISSN: 09396411 NLM ISO Abbreviation: Eur J Pharm Biopharm Subsets: MEDLINE

مواضيع طبية MeSH: Exenatide*/pharmacokinetics , Exenatide*/administration & dosage , Exenatide*/pharmacology , Liraglutide*/pharmacology , Liraglutide*/pharmacokinetics , Liraglutide*/administration & dosage , Peptides*/pharmacokinetics , Peptides*/administration & dosage , Rats, Sprague-Dawley*, Animals ; Rats ; Male ; Lipids/chemistry ; Half-Life ; Venoms/pharmacokinetics ; Venoms/administration & dosage ; Biological Availability ; Tissue Distribution ; Injections, Subcutaneous ; Lymph/metabolism ; Lymph/drug effects ; Glucagon-Like Peptide-1 Receptor/agonists ; Glucagon-Like Peptide-1 Receptor/metabolism ; Glucagon-Like Peptide 1/pharmacokinetics ; Glucagon-Like Peptide 1/metabolism ; Lymphatic System/metabolism ; Lymphatic System/drug effects ; Hypoglycemic Agents/pharmacokinetics ; Hypoglycemic Agents/administration & dosage ; Hypoglycemic Agents/pharmacology

المؤلفون: Khayyal MT; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt. mtkhayyal@gmail.com., Teaima MH; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt.; Center of Applied Research and advanced Studies (CARAS), Faculty of Pharmacy, Cairo University, Cairo, Egypt., Marzouk HM; Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo, ET-11562, Egypt.; Center of Applied Research and advanced Studies (CARAS), Faculty of Pharmacy, Cairo University, Cairo, Egypt., -Hazek RME; National Center for Radiation Research and Technology, Atomic Energy Authority, Cairo, Egypt., Behnam F; AQUANOVA AG, Darmstadt, Germany., Behnam D; AQUANOVA AG, Darmstadt, Germany.

المصدر: European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2024 Jul; Vol. 49 (4), pp. 467-475. Date of Electronic Publication: 2024 May 15.

نوع المنشور: Journal Article; Comparative Study; Randomized Controlled Trial

بيانات الدورية: Publisher: Springer France Country of Publication: France NLM ID: 7608491 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2107-0180 (Electronic) Linking ISSN: 03787966 NLM ISO Abbreviation: Eur J Drug Metab Pharmacokinet Subsets: MEDLINE

مواضيع طبية MeSH: Xanthophylls*/pharmacokinetics , Xanthophylls*/administration & dosage , Xanthophylls*/blood , Micelles* , Cross-Over Studies* , Area Under Curve* , Healthy Volunteers*, Humans ; Male ; Adult ; Young Adult ; Administration, Oral ; Half-Life ; Biological Availability ; Capsules/pharmacokinetics ; Chromatography, High Pressure Liquid/methods

المؤلفون: Bian YC; Department of Pharmacy, The First Affiliated Hospital of Soochow University, Suzhou, China.; Institute for Interdisciplinary Drug Research and Translational Sciences, Soochow University, Suzhou, China., Meng J; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China., Hu T; Department of Pharmacy, The First Affiliated Hospital of Soochow University, Suzhou, China.; Institute for Interdisciplinary Drug Research and Translational Sciences, Soochow University, Suzhou, China., Ma S; Department of Pharmacy, The First Affiliated Hospital of Soochow University, Suzhou, China.; Institute for Interdisciplinary Drug Research and Translational Sciences, Soochow University, Suzhou, China., Huang CR; Department of Pharmacy, The First Affiliated Hospital of Soochow University, Suzhou, China.; Institute for Interdisciplinary Drug Research and Translational Sciences, Soochow University, Suzhou, China., Zhang FY; Haisco Pharmaceutical Group Company Ltd., Chengdu, China., Wu QH; Haisco Pharmaceutical Group Company Ltd., Chengdu, China., Zhang H; Department of Pharmacy, The First Affiliated Hospital of Soochow University, Suzhou, China.; Institute for Interdisciplinary Drug Research and Translational Sciences, Soochow University, Suzhou, China., Chen XY; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China., Miao LY; Department of Pharmacy, The First Affiliated Hospital of Soochow University, Suzhou, China.; Institute for Interdisciplinary Drug Research and Translational Sciences, Soochow University, Suzhou, China.; National Clinical Research Center for Hematologic Diseases, The First Affiliated Hospital of Soochow University, Suzhou, China.

المصدر: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2024 Jul; Vol. 26 (7), pp. 2860-2868. Date of Electronic Publication: 2024 Apr 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

مواضيع طبية MeSH: Dipeptidyl-Peptidase IV Inhibitors*/pharmacokinetics , Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 2*/metabolism, Humans ; Male ; Adult ; Biotransformation ; Half-Life ; Feces/chemistry ; Young Adult ; Healthy Volunteers ; Hypoglycemic Agents/pharmacokinetics ; Hypoglycemic Agents/therapeutic use ; Administration, Oral

المؤلفون: Bhusal P; Ruminant Biotech Corp Limited, Hamilton, New Zealand., Lay MC; School of Engineering, University of Waikato, Hamilton, New Zealand., Kraakman KL; Ruminant Biotech Corp Limited, Hamilton, New Zealand., Corbett GE; Ruminant Biotech Corp Limited, Hamilton, New Zealand., Gladden NR; Ruminant Biotech Corp Limited, Hamilton, New Zealand.

المصدر: New Zealand veterinary journal [N Z Vet J] 2024 Jul; Vol. 72 (4), pp. 183-190. Date of Electronic Publication: 2024 Apr 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 0021406 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1176-0710 (Electronic) Linking ISSN: 00480169 NLM ISO Abbreviation: N Z Vet J Subsets: MEDLINE

مواضيع طبية MeSH: Trihalomethanes*/pharmacokinetics , Trihalomethanes*/administration & dosage , Trihalomethanes*/blood, Animals ; Cattle ; Female ; Administration, Oral ; Half-Life ; Area Under Curve ; Dose-Response Relationship, Drug ; Dairying

المؤلفون: Harlan SS; Department of Pharmacy Services, Baptist Memorial Hospital, Memphis, TN, USA.; Department of Clinical Pharmacy and Translational Science, University of Tennessee College of Pharmacy, Memphis, TN, USA., Philpott CD; Department of Pharmacy Services, UC Health-University of Cincinnati Medical Center, Cincinnati, OH, USA.; Division of Pharmacy Practice & Administrative Sciences, James L Winkle College of Pharmacy, University of Cincinnati, Cincinnati, OH, USA., Keegan SP; Esperion Therapeutics, Ann Arbor, MI, USA., Droege ME; Department of Pharmacy Services, UC Health-University of Cincinnati Medical Center, Cincinnati, OH, USA.; Division of Pharmacy Practice & Administrative Sciences, James L Winkle College of Pharmacy, University of Cincinnati, Cincinnati, OH, USA., Karve AS; Division of Pharmaceutical Sciences, James L Winkle College of Pharmacy, University of Cincinnati, Cincinnati, OH, USA., Foreman B; Division of Neurocritical Care, Department of Neurology and Rehabilitation Medicine, College of Medicine, University of Cincinnati, Cincinnati, OH, USA., Wakefield D; Division of Trauma and Surgical Critical Care, Department of Surgery, College of Medicine, University of Cincinnati, Cincinnati, OH, USA., Mueller EW; Department of Pharmacy Services, UC Health-University of Cincinnati Medical Center, Cincinnati, OH, USA.; Division of Pharmacy Practice & Administrative Sciences, James L Winkle College of Pharmacy, University of Cincinnati, Cincinnati, OH, USA., Sangha K; Department of Pharmacy Services, UC Health-University of Cincinnati Medical Center, Cincinnati, OH, USA.; Division of Pharmacy Practice & Administrative Sciences, James L Winkle College of Pharmacy, University of Cincinnati, Cincinnati, OH, USA.; Community of Scholars Faculty, College of Medicine, University of Cincinnati, Cincinnati, OH, USA., Ngwenya LB; Department of Neurosurgery, Department of Neurology and Rehabilitation Medicine, College of Medicine, University of Cincinnati, Cincinnati, OH, USA., Courter JD; Department of Pharmacy Services, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Desai P; Division of Pharmaceutical Sciences, James L Winkle College of Pharmacy, University of Cincinnati, Cincinnati, OH, USA., Droege C; Department of Pharmacy Services, UC Health-University of Cincinnati Medical Center, Cincinnati, OH, USA.; Division of Pharmacy Practice & Administrative Sciences, James L Winkle College of Pharmacy, University of Cincinnati, Cincinnati, OH, USA.

المصدر: The Annals of pharmacotherapy [Ann Pharmacother] 2024 Jul; Vol. 58 (7), pp. 705-714. Date of Electronic Publication: 2023 Sep 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Sage Country of Publication: United States NLM ID: 9203131 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-6270 (Electronic) Linking ISSN: 10600280 NLM ISO Abbreviation: Ann Pharmacother Subsets: MEDLINE

مواضيع طبية MeSH: Levetiracetam*/pharmacokinetics , Levetiracetam*/administration & dosage , Anticonvulsants*/pharmacokinetics , Anticonvulsants*/administration & dosage , Brain Injuries, Traumatic* , Seizures*/prevention & control , Seizures*/drug therapy, Humans ; Male ; Prospective Studies ; Middle Aged ; Adult ; Monte Carlo Method ; Critical Illness ; Piracetam/analogs & derivatives ; Piracetam/pharmacokinetics ; Piracetam/administration & dosage ; Aged ; Half-Life

المؤلفون: Najjar A; Beiersdorf AG, Beiersdorfstr. 1-9, 20245, Hamburg, Germany. Abdulkarim.Najjar@Beiersdorf.com., Grégoire S; L'Oreal Research & Innovation, Aulnay-Sous-Bois, France., Nicol B; Safety and Environmental Assurance Centre, Unilever UK, Colworth Science Park, MK44 1LQ, Sharnbrook, United Kingdom., Natsch A; Givaudan Schweiz AG, CH-8310, Kemptthal, Switzerland., Golbamaki N; L'Oreal Research & Innovation, Aulnay-Sous-Bois, France., Boisleve F; Chanel, Neuilly, France., Irizar A; The International Fragrance Association (IFRA), Geneva, Switzerland., Wall B; Colgate-Palmolive Company, Piscataway, NJ, 08854, USA., Swinscoe A; Whitman Laboratories, The Estée Lauder Companies, Petersfield, United Kingdom., Masini-Etévé V; L'Oréal Recherche & Innovation, Clichy, France., Selechnik D; Research Institute for Fragrance Materials (RIFM), Inc., Woodcliff Lake, NJ, USA., Api AM; Research Institute for Fragrance Materials (RIFM), Inc., Woodcliff Lake, NJ, USA., Griem P; Symrise AG, Holzminden, Germany., Hewitt N; SWS, Erzhausen, Germany., Cardamone E; Cosmetics Europe, Brussels, Belgium.

المصدر: Archives of toxicology [Arch Toxicol] 2024 Jul; Vol. 98 (7), pp. 2199-2211. Date of Electronic Publication: 2024 Apr 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Salicylic Acid*/pharmacokinetics , Salicylic Acid*/metabolism , Esters*, Humans ; Cosmetics ; Models, Biological ; Administration, Cutaneous ; Liver/metabolism ; Liver/drug effects ; Half-Life ; Skin/metabolism ; Skin/drug effects ; Computer Simulation ; Skin Absorption