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1دورية أكاديمية
المؤلفون: Julia Schanda, Chun-Wei Lee, Katharina Wohlan, Uta Müller-Kuller, Hana Kunkel, Isabell Quagliano-Lo Coco, Stefan Stein, Alexander Metz, Joachim Koch, Jörn Lausen, Uwe Platzbecker, Hind Medyouf, Holger Gohlke, Michael Heuser, Matthias Eder, Manuel Grez, Michaela Scherr, Christian Wichmann
المصدر: Haematologica, Vol 102, Iss 5 (2017)
مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5
وصف الملف: electronic resource
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المؤلفون: Axel Schambach, Sabine Charrier, Uta Müller-Kuller, Ute Modlich, Michael Rothe, Bobby Gaspar, Christian Brendel, Manuel Grez, Adrian J. Thrasher, Anne Galy, Daniela Abriss, Hana Kunkel, Stefan Stein, Giorgia Santilli
المساهمون: Barenbrug, Approches génétiques intégrées et nouvelles thérapies pour les maladies rares (INTEGRARE), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université d'Évry-Val-d'Essonne (UEVE)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Généthon, Généthon, École Pratique des Hautes Études (EPHE)
المصدر: Hum Gene Ther Clin Dev
Hum Gene Ther Clin Dev, 2018, 29, pp.69-79. ⟨10.1089/humc.2017.245⟩
Human gene therapy. Clinical development
Human gene therapy. Clinical development, 2018, 29 (2), pp.69-79. ⟨10.1089/humc.2017.245⟩مصطلحات موضوعية: 0301 basic medicine, Transgene, Genetic enhancement, [SDV]Life Sciences [q-bio], Genetic Vectors, CD34, Granulomatous Disease, Chronic, Viral vector, Mice, 03 medical and health sciences, Chronic granulomatous disease, In vivo, medicine, Animals, Humans, Genetics (clinical), Clinical Trials as Topic, business.industry, Lentivirus, NADPH Oxidases, Genetic Diseases, X-Linked, Genetic Therapy, Hematopoietic Stem Cells, medicine.disease, 3. Good health, Haematopoiesis, 030104 developmental biology, Gene Expression Regulation, NADPH Oxidase 2, Cancer research, Heterografts, [SDV.IMM]Life Sciences [q-bio]/Immunology, business, Homing (hematopoietic)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef25248bf2b13c212f3150b10f5ad753
https://hal.archives-ouvertes.fr/hal-02880787 -
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المؤلفون: Finn K. Hansen, Daniela Diedrich, Joachim Jose, Viktoria Marquardt, Friederike V. Opitz, Arndt Borkhardt, Hana Kunkel, Matthias U. Kassack, Luitgard Nagel-Steger, Florian Babor, Manuel Grez, Heinz Ahlert, Thomas Kurz, Stefan Stein, Ana J. Rodrigues Moita, Tobias Kröger, Sanil Bhatia, Steffen Lüdeke, Marina Oldenburg, Holger Gohlke, Bertan Bopp, Gesine Kögler, Andreas Hochhaus, Marc Remke, Franziska Lang, Julia Hauer, Andreas Krieg, Benedikt Frieg, Tao Zang, Georg Groth, Thomas Ernst
المصدر: Blood. 132(3)
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Fusion Proteins, bcr-abl, Molecular Conformation, CD38, Biochemistry, Tyrosine-kinase inhibitor, Hsp90 inhibitor, Mice, 0302 clinical medicine, hemic and lymphatic diseases, Myeloid Neoplasia, Molecular Structure, Chemistry, Cell Cycle, Myeloid leukemia, Hematology, Leukemia, 030220 oncology & carcinogenesis, Imatinib Mesylate, Dimerization, BLOOD Commentary, Protein Binding, medicine.drug_class, Cell Survival, Immunology, Antineoplastic Agents, 03 medical and health sciences, Structure-Activity Relationship, Heat shock protein, Cell Line, Tumor, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, medicine, Biomarkers, Tumor, Animals, Humans, Protein Interaction Domains and Motifs, HSP90 Heat-Shock Proteins, Heat shock, Protein Kinase Inhibitors, Binding Sites, Spectrum Analysis, Cell Biology, medicine.disease, Xenograft Model Antitumor Assays, Disease Models, Animal, 030104 developmental biology, Imatinib mesylate, Drug Resistance, Neoplasm, Cancer research, Protein Multimerization, Heat-Shock Response
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a07fbe0af7a54174df392aecf16dc75
https://pubmed.ncbi.nlm.nih.gov/30026301 -
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المؤلفون: Alejandro H. Corvalan, Hana Kunkel, Helga Weber, Akhilesh Pandey, Jeffrey W. Tyner, Carolina Bizama, Jose R. Valbuena, Manuel Grez, Stefan Stein, Stephen E. Kurtz, Mustafa A. Barbhuiya, Ismael Riquelme, Jaime A. Espinoza, Patricia García, Pamela Leal-Rojas, Juan F. Calderón, Juan Carlos Roa
المصدر: Oncotarget
مصطلحات موضوعية: 0301 basic medicine, Oncology, Pathology, medicine.medical_treatment, Apoptosis, Hsp90 inhibitor, gallbladder cancer, Mice, 0302 clinical medicine, Cell Movement, Drug Discovery, Benzoquinones, polycyclic compounds, 17-AAG, Hematology, 030220 oncology & carcinogenesis, Gallbladder Neoplasms, Research Paper, medicine.medical_specialty, Cell Survival, Lactams, Macrocyclic, Antineoplastic Agents, Small Molecule Libraries, 03 medical and health sciences, Cell Line, Tumor, Internal medicine, medicine, Animals, Humans, HSP90 Heat-Shock Proteins, ddc:610, Gallbladder cancer, geldanamycin, HSP90 inhibitors, gallbladder cancer xenografts, Cell Proliferation, Chemotherapy, Translational oncology, business.industry, Cancer, Cell Cycle Checkpoints, medicine.disease, Xenograft Model Antitumor Assays, High-Throughput Screening Assays, Radiation therapy, Disease Models, Animal, 030104 developmental biology, Drug Screening Assays, Antitumor, business, Hematology+Oncology
وصف الملف: application/octet-stream
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e96df0f641496b91d05387af99746d
http://publikationen.ub.uni-frankfurt.de/files/44125/container.zip -
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المؤلفون: Rolf M. Nüsing, Nerea Ferreirós, Yannick Schreiber, Bernhard Brüne, Hana Kunkel, Marina Henke, Elsa-Marie Treutlein, Andreas Weigert, Claus-Dieter Schuh, Jing Suo, Manuel Grez, Benjamin Weichand, Gerd Geisslinger, Dong Dong Zhang, Sandra Pierre, Klaus Scholich, Kai Altenrath
المصدر: Pain. 155:545-555
مصطلحات موضوعية: Agonist, medicine.drug_class, Interleukin-1beta, Prostacyclin, Pharmacology, Mice, medicine, Animals, Prostacyclin receptor, Mice, Knockout, biology, business.industry, Macrophages, Interleukin, Nerve injury, Epoprostenol, Mice, Inbred C57BL, Anesthesiology and Pain Medicine, Gene Expression Regulation, Neurology, Anesthesia, Neuropathic pain, Knockout mouse, biology.protein, Neuralgia, Female, Neurology (clinical), Cyclooxygenase, medicine.symptom, business, medicine.drug
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المؤلفون: Hana Kunkel, Christian Brendel, Michael Antoniou, Adelina Dillmann, Stephan Schultze-Strasser, A Krattenmacher, Uta Müller-Kuller, Stefan Stein, Manuel Grez, Linping Chen-Wichmann
المصدر: Gene Therapy; Vol 19
Gene Therapyمصطلحات موضوعية: Transcription, Genetic, Chromosomal Proteins, Non-Histone, Transgene, Genetic Vectors, Biology, 03 medical and health sciences, Mice, 0302 clinical medicine, Epigenetics of physical exercise, Cell Line, Tumor, Heterogeneous-Nuclear Ribonucleoprotein Group A-B, Genetics, Transcriptional regulation, Gene silencing, Animals, Humans, Calgranulin A, Myeloid Cells, Epigenetics, Gene Silencing, Transgenes, Enhancer, Promoter Regions, Genetic, Molecular Biology, Cells, Cultured, 030304 developmental biology, Cell Line, Transformed, 0303 health sciences, Genes, Essential, Membrane Glycoproteins, Lentivirus, NADPH Oxidases, Promoter, Molecular biology, Mice, Mutant Strains, Chromatin, Cell biology, Up-Regulation, 030220 oncology & carcinogenesis, NADPH Oxidase 2, Molecular Medicine
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المؤلفون: Stefan Knapp, Gregor B. Deutsch, Hana Kunkel, Frank McKeon, Elisabeth M. Zielonka, Amparo Acker-Palmer, Birgit Schäfer, Frank H. Niesen, Jens Hannewald, Laura M. Luh, D. Coutandin, Jan Hoffmann, Tobias Alexander Weber, Volker Dötsch, Aycan Sentürk, Florian Durst, Manuel Grez, Mohamed Ibrahim, Bernd Brutschy, Enrico Schleiff
المصدر: Cell
مصطلحات موضوعية: Models, Molecular, DNA damage, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Dephosphorylation, Mice, 03 medical and health sciences, chemistry.chemical_compound, Transactivation, 0302 clinical medicine, Tetramer, ddc:570, Animals, Phosphorylation, Binding site, 030304 developmental biology, 0303 health sciences, Biochemistry, Genetics and Molecular Biology(all), DNA, Phosphoproteins, Cell biology, Biochemistry, chemistry, Gamma Rays, 030220 oncology & carcinogenesis, Oocytes, Trans-Activators, Female, Protein Multimerization, Tumor Suppressor Protein p53, Dimerization, Alpha helix
وصف الملف: application/octet-stream
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المؤلفون: Hana Kunkel, Juan Carlos Roa, Jaime A. Espinoza, Ismael Riquelme, Helga Weber, Bruno Nervi, Carolina Bizama, Pamela Leal, Stefan Stein, Manuel Grez, Juan Carlos Araya, Patricia García
المصدر: Oncotarget
مصطلحات موضوعية: medicine.medical_specialty, mTOR inhibitors, Guanine, medicine.medical_treatment, Blotting, Western, Apoptosis, Mice, SCID, Biology, Immunoenzyme Techniques, gallbladder cancer, Mice, In vivo, Cell Movement, Mice, Inbred NOD, Internal medicine, medicine, Tumor Cells, Cultured, Animals, Humans, Viability assay, ddc:610, Gallbladder cancer, Phosphorylation, PI3K/AKT/mTOR pathway, Cell Proliferation, gallbladder cancer xenografts, Sirolimus, Chemotherapy, Antibiotics, Antineoplastic, Cell growth, rapamycin, medicine.disease, Xenograft Model Antitumor Assays, WYE-354, Endocrinology, Oncology, Cancer research, Drug Therapy, Combination, Gallbladder Neoplasms, medicine.drug, Signal Transduction, Research Paper
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be4c7ecf215ddbb9fdf93815028af7d
https://pubmed.ncbi.nlm.nih.gov/26397134 -
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المؤلفون: Thomas Moritz, Christian Brendel, Jessica Fritsch, Manuel Grez, Nico Lachmann, Jörn Lausen, Hana Kunkel, Uta Müller-Kuller, Stephan Kolodziej, Mania Ackermann, Axel Schambach
المصدر: Nucleic Acids Research
مصطلحات موضوعية: Pluripotent Stem Cells, Chromatin Immunoprecipitation, Cellular differentiation, Transgene, Cell Separation, Biology, Polymerase Chain Reaction, Epigenesis, Genetic, Mice, Cell Line, Tumor, ddc:570, Genetics, Animals, Humans, Gene silencing, Gene Silencing, Transgenes, Epigenetics, ddc:610, Promoter Regions, Genetic, Induced pluripotent stem cell, Multipotent Stem Cells, Gene regulation, Chromatin and Epigenetics, Cell Differentiation, Promoter, Flow Cytometry, Chromatin, Mice, Inbred C57BL, Cancer research, Chromatin immunoprecipitation
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2930fb78a0058f2ba8fc650a556caf16
http://publikationen.ub.uni-frankfurt.de/files/37385/Nucl_Acids_Res-2015-Mueller-Kuller-1577-92.pdf -
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المؤلفون: Martijn H. Brugman, Hana Kunkel, Christian Brendel, Kerstin B. Kaufmann, Tobias Abel, Manuel Grez, Hubert Serve, Linping Chen-Wichmann, Sabrina Kneissl, Uta Müller-Kuller, Leonid Bystrykh, Benjamin Goebel, Joachim Schwäble, Christian J. Buchholz, Abriss Daniela
المساهمون: Stem Cell Aging Leukemia and Lymphoma (SALL)
المصدر: Molecular Therapy, 23(1), 63-70. CELL PRESS
مصطلحات موضوعية: Genetic enhancement, Gene Expression, Antigens, CD34, Granulomatous Disease, Chronic, Mice, MOLECULAR EVIDENCE, Viral Envelope Proteins, Transduction, Genetic, Drug Discovery, AC133 Antigen, Membrane Glycoproteins, PSEUDOTYPE LENTIVIRAL VECTORS, biology, IMMUNE-DEFICIENT MICE, ENVELOPE PROTEINS, MEASLES-VIRUS, CD34(+) CELLS, Cell biology, Haematopoiesis, Interleukin 12, Molecular Medicine, Original Article, Stem cell, Corrigendum, Genetic Vectors, Green Fluorescent Proteins, Primary Cell Culture, MOBILIZED PERIPHERAL-BLOOD, Vesicular stomatitis Indiana virus, LDL RECEPTOR, Viral vector, Antigens, CD, Genetics, Animals, Humans, Progenitor cell, Molecular Biology, Interleukin 3, Glycoproteins, Pharmacology, CD40, Lentivirus, Genetic Therapy, IN-VITRO, Hematopoietic Stem Cells, Virology, PROGENITOR CELLS, biology.protein, Leukocytes, Mononuclear, Peptides
وصف الملف: application/pdf
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