المؤلفون: Cristina St Pierre, Jane Guo, John D Shin, Laura W Engstrom, Hyun-Hee Lee, Alan Herbert, Laura Surdi, James Baker, Michael Salmon, Sanjiv Shah, J Michael Ellis, Hani Houshyar, Michael A Crackower, Melanie A Kleinschek, Dallas C Jones, Alexandra Hicks, Dennis M Zaller, Stephen E Alves, Ravisankar A Ramadas

المصدر: PLoS ONE, Vol 12, Iss 7, p e0180870 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5515432?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/a511e5553a1e4c19982a055d21745012

المؤلفون: Robert C. Bucelli, Manjit McNeill, Shafeeq Ladha, Angela Genge, Stephanie Fradette, Ivan Nestorov, John Ravits, Philip Van Damme, Roger Lane, Christopher J McDermott, Jonathan Glass, Merit Cudkowicz, Laura Fanning, C. Frank Bennett, Heiko Runz, Ih Chang, Hani Houshyar, Toby A. Ferguson, Alfred Sandrock, Alan Pestronk, Danielle Graham, Timothy M. Miller, Randall G. Trudell, Nazem Atassi, Peter M. Andersen, François Salachas, Nicholas J. Maragakis, Albert L. Ludolph, Pamela J. Shaw, Lorne Zinman, Alexander McCampbell

المصدر: New England Journal of Medicine. 383:109-119

مصطلحات موضوعية: Messenger RNA, Mutation, biology, business.industry, Oligonucleotide, animal diseases, SOD1, nutritional and metabolic diseases, General Medicine, 030204 cardiovascular system & hematology, Intrathecal, medicine.disease_cause, Molecular biology, nervous system diseases, Superoxide dismutase, 03 medical and health sciences, 0302 clinical medicine, nervous system, Antisense oligonucleotides, Protein biosynthesis, biology.protein, Medicine, 030212 general & internal medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cd89d37b574703a54dc8fa55df6264a4
https://doi.org/10.1056/nejmoa2003715

المؤلفون: Jason D. Katz, François G. Gervais, Lauren Dorosh, Milenko Cicmil, Khamir Mehta, Joey L. Methot, Janice D Woodhouse, Hongshi Yu, Hani Houshyar, Prasanthi Geda, Gretchen A. Baltus, Malgorzata A Gil, Antonio Cabal, Sanjiv J. Shah, Robbie L. McLeod, Dapeng Chen, Alan S. Bass, Stephen E. Alves, Michael Caniga

المصدر: Journal of Pharmacology and Experimental Therapeutics. 369:223-233

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, biology, Chemistry, Area under the curve, Cmax, Basophil, 03 medical and health sciences, Cmin, Ovalbumin, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Pharmacodynamics, Blood plasma, medicine, biology.protein, Molecular Medicine, IC50, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9ae30672ed16800c8692f183b1d4851d
https://doi.org/10.1124/jpet.118.252551

المؤلفون: Timothy, Miller, Merit, Cudkowicz, Pamela J, Shaw, Peter M, Andersen, Nazem, Atassi, Robert C, Bucelli, Angela, Genge, Jonathan, Glass, Shafeeq, Ladha, Albert L, Ludolph, Nicholas J, Maragakis, Christopher J, McDermott, Alan, Pestronk, John, Ravits, François, Salachas, Randall, Trudell, Philip, Van Damme, Lorne, Zinman, C Frank, Bennett, Roger, Lane, Alfred, Sandrock, Heiko, Runz, Danielle, Graham, Hani, Houshyar, Alexander, McCampbell, Ivan, Nestorov, Ih, Chang, Manjit, McNeill, Laura, Fanning, Stephanie, Fradette, Toby A, Ferguson

المصدر: The New England journal of medicine. 383(2)

مصطلحات موضوعية: Adult, Male, Dose-Response Relationship, Drug, Leukocytosis, Amyotrophic Lateral Sclerosis, Vital Capacity, Headache, Intermediate Filaments, Oligonucleotides, Middle Aged, Oligonucleotides, Antisense, Superoxide Dismutase-1, Double-Blind Method, Mutation, Disease Progression, Humans, Female, Injections, Spinal

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::60508a8fa4e2c3ceebe60cab1d91953b
https://pubmed.ncbi.nlm.nih.gov/32704069

المؤلفون: Robbie L, McLeod, Malgorzata A, Gil, Dapeng, Chen, Antonio, Cabal, Jason, Katz, Joey, Methot, Janice D, Woodhouse, Lauren, Dorosh, Prasanthi, Geda, Khamir, Mehta, Milenko, Cicmil, Gretchen A, Baltus, Alan, Bass, Hani, Houshyar, Michael, Caniga, Hongshi, Yu, Francois, Gervais, Stephen, Alves, Sanjiv, Shah

المصدر: The Journal of pharmacology and experimental therapeutics. 369(2)

مصطلحات موضوعية: Inflammation, Male, Disease Models, Animal, Phosphatidylinositol 3-Kinases, Th2 Cells, Respiratory Tract Diseases, Animals, Humans, Th1 Cells, Phosphoinositide-3 Kinase Inhibitors, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::a514c7e08b5e85828f6fd96b70fba955
https://pubmed.ncbi.nlm.nih.gov/30804001

المؤلفون: Hani Houshyar, Alanna R. Darling, Joseph S. Zhou, Magali Noval Rivas, Kyle J. Koleoglou, Michael A. Crackower, Oliver T. Burton, Axel Roers, Hans C. Oettgen, Stephanie L. Logsdon, Talal A. Chatila

المصدر: Immunity. 41:141-151

مصطلحات موضوعية: 0303 health sciences, Allergy, biology, medicine.medical_treatment, Immunology, Peanut allergy, Syk, Immunoglobulin E, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, Infectious Diseases, medicine.anatomical_structure, Food allergy, biology.protein, medicine, Immunology and Allergy, Antibody, Sensitization, 030304 developmental biology, 030215 immunology, Desensitization (medicine)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c04bbc33358bec38ebee87d022c73f2
https://doi.org/10.1016/j.immuni.2014.05.017

المؤلفون: Emily Hickey, Stella H. Vincent, Hongshi Yu, John H. Shin, Michael A. Crackower, Hyun-Hee Lee, Malgorzata A Gil, Michael Caniga, Jessica P. Alexander, Lily Y. Moy, Alan B. Northrup, Gissela Lieber, Richard L. Miller, Richard W. Chapman, Erich E Sirkowski, Thomas A. Miller, Yanlin Jia, Hani Houshyar, Nancy Kelly, J. Michael Ellis, Xiomara Fernandez, Alan Wilhelm, Hongmin Chen, William M. Abraham

المصدر: American Journal of Respiratory Cell and Molecular Biology. 49:1085-1092

مصطلحات موضوعية: Male, Pulmonary and Respiratory Medicine, Ovalbumin, Bronchoconstriction, Clinical Biochemistry, Syk, Inflammation, Immunoglobulin E, Cell Degranulation, Allergic inflammation, Rats, Sprague-Dawley, Rats, Inbred BN, Animals, Humans, Syk Kinase, Medicine, Mast Cells, Protein Kinase Inhibitors, Molecular Biology, Ascaris suum, Sheep, biology, business.industry, FCER1, Intracellular Signaling Peptides and Proteins, hemic and immune systems, Cell Biology, Allergens, Protein-Tyrosine Kinases, respiratory system, Asthma, Extravasation, Rats, respiratory tract diseases, Disease Models, Animal, Macaca fascicularis, Immunology, biology.protein, medicine.symptom, Signal transduction, business, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62d70a91ae24da5195de5671fc3542c
https://doi.org/10.1165/rcmb.2013-0200oc

المؤلفون: Sheila M. Galloway, Binyuan Sun, Nancy Kelly, John W. Butcher, Grace H. C. Woo, Kerrie Spencer, J. Michael Ellis, Ryan D. Otte, Ekundayo Osimboni, Alan S. Bass, Sandra Lee, J. Richard Miller, Chiming Yang, Erica Leccese, Andrew M. Haidle, Alan B. Northrup, Lily Y. Moy, James P. Jewell, Alan Byford, Hani Houshyar, Gwendolyn J. Ward, Anthony Donofrio, Matthew L. Maddess, Michael D. Altman, M. Vijay Reddy, Stella H. Vincent

المصدر: Journal of medicinal chemistry. 58(4)

مصطلحات موضوعية: Models, Molecular, hERG, Intercalation (chemistry), Syk, Crystallography, X-Ray, Ames test, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, Structure–activity relationship, Humans, A-DNA, Protein Kinase Inhibitors, biology, Dose-Response Relationship, Drug, Molecular Structure, Mutagenicity Tests, Ligand binding assay, Protein-Tyrosine Kinases, Amides, Ether-A-Go-Go Potassium Channels, Biochemistry, chemistry, biology.protein, Molecular Medicine, DNA, Spleen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040b080e82842dc9548a30636c5cf5d6
https://pubmed.ncbi.nlm.nih.gov/25625541

المؤلفون: Abigail B. Ginsberg, Susanne E. la Fleur, Francisca Gomez, Kevin D. Laugero, Mary F. Dallman, Hani Houshyar, Susan F. Akana, Norman C. Pecoraro, James P. Warne, Aditi Bhargava

المصدر: Progress in neurobiology. 79(5-6):247-340

مصطلحات موضوعية: Hypothalamo-Hypophyseal System, Motivation, endocrine system, Metabolic derangement, General Neuroscience, Stressor, Hypothalamo pituitary adrenal axis, Pituitary-Adrenal System, Phenotype, Models, Biological, Fight-or-flight response, Hpa activity, Stress, Physiological, Neural Pathways, Psychogenic disease, Animals, Humans, Nerve Net, Psychology, Neuroscience, Glucocorticoids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2143e4138ba8c07bd7e8134cddc116a9
https://doi.org/10.1016/j.pneurobio.2006.07.004

المؤلفون: James H. Woods, Susan K Wood, Hani Houshyar, Kenner C. Rice, Emily M. Jutkiewicz, Ling-Wei Hsin

المصدر: Psychopharmacology. 180:215-223

مصطلحات موضوعية: Male, Restraint, Physical, Hypothalamo-Hypophyseal System, medicine.medical_specialty, Corticotropin-Releasing Hormone, Pituitary-Adrenal System, Adrenocorticotropic hormone, Article, Rats, Sprague-Dawley, Corticotropin-releasing hormone, Adrenocorticotropic Hormone, Internal medicine, medicine, Animals, Pyrroles, Antalarmin, Swimming, Depression (differential diagnoses), Pharmacology, Antagonist, Triazoles, Antidepressive Agents, Rats, Extreme stress, Pyrimidines, Endocrinology, Psychology, Stress, Psychological, Hormone, Behavioural despair test, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009f5b5f6c02efd535ec779ed99dcc7e
https://doi.org/10.1007/s00213-005-2164-z