المؤلفون: Shen Y; Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA., Voigt A; Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA., Goranova L; Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA., Abed M; Salivary Disorder Unit, National Institute of Dental and Craniofacial Research, NIH, Bethesda, Maryland, USA., Kleiner DE; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland, USA., Maldonado JO; Salivary Disorder Unit, National Institute of Dental and Craniofacial Research, NIH, Bethesda, Maryland, USA.; AAV Biology Section, National Institute of Dental and Craniofacial Research, NIH, Bethesda, Maryland, USA.; Center for Oral Health Integration, HealthPartners Institute, Bloomington, MN, USA., Beach M; Salivary Disorder Unit, National Institute of Dental and Craniofacial Research, NIH, Bethesda, Maryland, USA., Pelayo E; Salivary Disorder Unit, National Institute of Dental and Craniofacial Research, NIH, Bethesda, Maryland, USA., Chiorini JA; AAV Biology Section, National Institute of Dental and Craniofacial Research, NIH, Bethesda, Maryland, USA., Craft WF; Department of Comparative, Diagnostic, and Population Medicine, College of Veterinary Medicine, and., Ostrov DA; Department of Pathology, Immunology & Laboratory Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA., Ramiya V; LifeSouth Community Blood Centers, Gainesville, Florida, USA., Sukumaran S; Valley Children's Hospital, Madera, California., Brown AN; Institute for Therapeutic Innovation, Department of Medicine, University of Florida College of Medicine, Orlando, Florida, USA., Hanrahan KC; Institute for Therapeutic Innovation, Department of Medicine, University of Florida College of Medicine, Orlando, Florida, USA., Tuanyok A; Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA., Warner BM; Salivary Disorder Unit, National Institute of Dental and Craniofacial Research, NIH, Bethesda, Maryland, USA., Nguyen CQ; Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.; Department of Oral Biology, College of Dentistry and.; Center of Orphaned Autoimmune Diseases, University of Florida, Gainesville, Florida, USA.

المصدر: JCI insight [JCI Insight] 2023 Dec 22; Vol. 8 (24). Date of Electronic Publication: 2023 Dec 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19* , Sjogren's Syndrome*, Humans ; Mice ; Male ; Female ; Animals ; Angiotensin-Converting Enzyme 2/genetics ; SARS-CoV-2 ; Mice, Transgenic ; Phenotype

المؤلفون: Franco EJ; Institute for Therapeutic Innovation, Department of Medicine, College of Medicine, University of Florida, Orlando, FL 32827, USA.; Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, FL 32827, USA., Cella E; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32827, USA., Tao X; Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, FL 32827, USA., Hanrahan KC; Institute for Therapeutic Innovation, Department of Medicine, College of Medicine, University of Florida, Orlando, FL 32827, USA., Azarian T; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32827, USA., Brown AN; Institute for Therapeutic Innovation, Department of Medicine, College of Medicine, University of Florida, Orlando, FL 32827, USA.; Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, FL 32827, USA.

المصدر: Microorganisms [Microorganisms] 2023 May 19; Vol. 11 (5). Date of Electronic Publication: 2023 May 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101625893 Publication Model: Electronic Cited Medium: Print ISSN: 2076-2607 (Print) Linking ISSN: 20762607 NLM ISO Abbreviation: Microorganisms Subsets: PubMed not MEDLINE

المؤلفون: Franco EJ; Institute for Therapeutic Innovation, Department of Medicine, College of Medicine, University of Florida, Orlando, FL 32827, USA.; Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, FL 32827, USA., Drusano GL; Institute for Therapeutic Innovation, Department of Medicine, College of Medicine, University of Florida, Orlando, FL 32827, USA., Hanrahan KC; Institute for Therapeutic Innovation, Department of Medicine, College of Medicine, University of Florida, Orlando, FL 32827, USA., Warfield KL; Emergent BioSolutions, Gaithersburg, MD 20879, USA., Brown AN; Institute for Therapeutic Innovation, Department of Medicine, College of Medicine, University of Florida, Orlando, FL 32827, USA.; Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, FL 32827, USA.

المصدر: Viruses [Viruses] 2023 May 16; Vol. 15 (5). Date of Electronic Publication: 2023 May 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: Angiotensin-Converting Enzyme 2* , COVID-19*, Humans ; SARS-CoV-2 ; Antiviral Agents/pharmacology

SCR Organism: SARS-CoV-2 variants

المؤلفون: Franco EJ; Institute for Therapeutic Innovation, Department of Medicine, University of Florida College of Medicine, Orlando, FL 32827, USA.; Department of Pharmaceutics, University of Florida College of Pharmacy, Orlando, FL 32827, USA., Hanrahan KC; Institute for Therapeutic Innovation, Department of Medicine, University of Florida College of Medicine, Orlando, FL 32827, USA., Brown AN; Institute for Therapeutic Innovation, Department of Medicine, University of Florida College of Medicine, Orlando, FL 32827, USA.; Department of Pharmaceutics, University of Florida College of Pharmacy, Orlando, FL 32827, USA.

المصدر: Microorganisms [Microorganisms] 2023 Apr 22; Vol. 11 (5). Date of Electronic Publication: 2023 Apr 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101625893 Publication Model: Electronic Cited Medium: Print ISSN: 2076-2607 (Print) Linking ISSN: 20762607 NLM ISO Abbreviation: Microorganisms Subsets: PubMed not MEDLINE

المؤلفون: Karade SS; University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, Maryland 20850, United States.; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, United States., Franco EJ; Institute for Therapeutic Innovation, Department of Medicine, College of Medicine, University of Florida, Orlando, Florida 32827, United States., Rojas AC; Institute for Therapeutic Innovation, Department of Medicine, College of Medicine, University of Florida, Orlando, Florida 32827, United States., Hanrahan KC; Institute for Therapeutic Innovation, Department of Medicine, College of Medicine, University of Florida, Orlando, Florida 32827, United States., Kolesnikov A; University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, Maryland 20850, United States.; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, United States., Yu W; University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, Maryland 20850, United States.; Computer-Aided Drug Design Center, Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201, United States.; Center for Biomolecular Therapeutics (CBT), Department of Biochemistry and Molecular Biology, School of Medicine, University of Maryland, Baltimore, Maryland 21201, United States., MacKerell AD Jr; University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, Maryland 20850, United States.; Computer-Aided Drug Design Center, Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201, United States.; Center for Biomolecular Therapeutics (CBT), Department of Biochemistry and Molecular Biology, School of Medicine, University of Maryland, Baltimore, Maryland 21201, United States., Hill DC; Emergent BioSolutions, Gaithersburg, Maryland 20879, United States., Weber DJ; University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, Maryland 20850, United States.; Center for Biomolecular Therapeutics (CBT), Department of Biochemistry and Molecular Biology, School of Medicine, University of Maryland, Baltimore, Maryland 21201, United States., Brown AN; Institute for Therapeutic Innovation, Department of Medicine, College of Medicine, University of Florida, Orlando, Florida 32827, United States., Treston AM; Emergent BioSolutions, Gaithersburg, Maryland 20879, United States., Mariuzza RA; University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, Maryland 20850, United States.; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland 20742, United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2023 Feb 23; Vol. 66 (4), pp. 2744-2760. Date of Electronic Publication: 2023 Feb 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: 1-Deoxynojirimycin*/chemistry , 1-Deoxynojirimycin*/pharmacology , alpha-Glucosidases*/drug effects , Antiviral Agents*/chemistry , Antiviral Agents*/pharmacology , COVID-19* , Glycoside Hydrolase Inhibitors*/chemistry , Glycoside Hydrolase Inhibitors*/pharmacology, Animals ; Endoplasmic Reticulum/enzymology ; Glycoproteins ; SARS-CoV-2/metabolism ; Quantitative Structure-Activity Relationship

المؤلفون: Brown AN; Institute for Therapeutic Innovation, University of Floridagrid.15276.37, Orlando, Florida, USA.; Department of Medicine, College of Medicine, University of Floridagrid.15276.37, Orlando, Florida, USA.; Department of Pharmaceutics, College of Pharmacy, University of Floridagrid.15276.37, Orlando, Florida, USA., Lang Y; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Floridagrid.15276.37, Orlando, Florida, USA., Zhou J; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Floridagrid.15276.37, Orlando, Florida, USA., Franco EJ; Institute for Therapeutic Innovation, University of Floridagrid.15276.37, Orlando, Florida, USA.; Department of Pharmaceutics, College of Pharmacy, University of Floridagrid.15276.37, Orlando, Florida, USA., Hanrahan KC; Institute for Therapeutic Innovation, University of Floridagrid.15276.37, Orlando, Florida, USA.; Department of Medicine, College of Medicine, University of Floridagrid.15276.37, Orlando, Florida, USA., Bulitta JB; Institute for Therapeutic Innovation, University of Floridagrid.15276.37, Orlando, Florida, USA.; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Floridagrid.15276.37, Orlando, Florida, USA., Drusano GL; Institute for Therapeutic Innovation, University of Floridagrid.15276.37, Orlando, Florida, USA.; Department of Medicine, College of Medicine, University of Floridagrid.15276.37, Orlando, Florida, USA.

المصدر: MBio [mBio] 2022 Dec 20; Vol. 13 (6), pp. e0291622. Date of Electronic Publication: 2022 Nov 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19*, Humans ; SARS-CoV-2 ; Antiviral Agents

المؤلفون: Brown AN; Institute for Therapeutic Innovation, Department of Medicine, College of Medicine, University of Florida, Orlando, FL 32827, USA., Strobel G; Department of Plant Sciences, Montana State University, Bozeman, MT 59715, USA., Hanrahan KC; Institute for Therapeutic Innovation, Department of Medicine, College of Medicine, University of Florida, Orlando, FL 32827, USA., Sears J; Center for Lab Services/RJ Lee Group, Pasco, WA 99301, USA.

المصدر: Viruses [Viruses] 2021 Mar 05; Vol. 13 (3). Date of Electronic Publication: 2021 Mar 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: Antiviral Agents/*pharmacology , Caproates/*pharmacology , Propionates/*pharmacology , SARS-CoV-2/*drug effects, Animals ; COVID-19/virology ; Chlorocebus aethiops ; Drug Compounding ; Drug Evaluation, Preclinical ; Humans ; SARS-CoV-2/genetics ; SARS-CoV-2/physiology ; Vero Cells ; Virus Replication/drug effects

المؤلفون: Franco EJ; Institute for Therapeutic Innovation, Department of Medicine, College of Medicine, University of Florida, Orlando, FL 32827, USA.; Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, FL 32827, USA., Tao X; Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, FL 32827, USA., Hanrahan KC; Institute for Therapeutic Innovation, Department of Medicine, College of Medicine, University of Florida, Orlando, FL 32827, USA., Zhou J; Department of Pharmacotherapy & Translational Research, College of Pharmacy, University of Florida, Orlando, FL 32827, USA., Bulitta JB; Department of Pharmacotherapy & Translational Research, College of Pharmacy, University of Florida, Orlando, FL 32827, USA., Brown AN; Institute for Therapeutic Innovation, Department of Medicine, College of Medicine, University of Florida, Orlando, FL 32827, USA.; Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, FL 32827, USA.

المصدر: Microorganisms [Microorganisms] 2021 Feb 02; Vol. 9 (2). Date of Electronic Publication: 2021 Feb 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101625893 Publication Model: Electronic Cited Medium: Print ISSN: 2076-2607 (Print) Linking ISSN: 20762607 NLM ISO Abbreviation: Microorganisms Subsets: PubMed not MEDLINE

المؤلفون: Franco EJ; Department of Medicine, Institute for Therapeutic Innovation, University of Florida College of Medicine, Orlando, FL, USA.; Department of Pharmaceutics, University of Florida College of Pharmacy, Orlando, FL, USA., Rodriquez JL; Department of Medicine, Institute for Therapeutic Innovation, University of Florida College of Medicine, Orlando, FL, USA., Pomeroy JJ; Department of Medicine, Institute for Therapeutic Innovation, University of Florida College of Medicine, Orlando, FL, USA., Hanrahan KC; Department of Medicine, Institute for Therapeutic Innovation, University of Florida College of Medicine, Orlando, FL, USA., Brown AN; Department of Medicine, Institute for Therapeutic Innovation, University of Florida College of Medicine, Orlando, FL, USA.

المصدر: Antiviral chemistry & chemotherapy [Antivir Chem Chemother] 2018 Jan-Dec; Vol. 26, pp. 2040206618807580.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Sage Publications Country of Publication: England NLM ID: 9009212 Publication Model: Print Cited Medium: Internet ISSN: 2040-2066 (Electronic) Linking ISSN: 09563202 NLM ISO Abbreviation: Antivir Chem Chemother Subsets: MEDLINE

مواضيع طبية MeSH: Amides/*pharmacology , Antiviral Agents/*pharmacology , Chikungunya Fever/*drug therapy , Chikungunya virus/*drug effects , Interferon-alpha/*pharmacology , Pyrazines/*pharmacology , Ribavirin/*pharmacology, A549 Cells ; Amides/chemistry ; Animals ; Antiviral Agents/chemistry ; Cell Line, Tumor ; Chlorocebus aethiops ; Dose-Response Relationship, Drug ; Humans ; Interferon-alpha/chemistry ; Microbial Sensitivity Tests ; Molecular Structure ; Pyrazines/chemistry ; Ribavirin/chemistry ; Structure-Activity Relationship ; Vero Cells