المؤلفون: Mahad DJ, Ziabreva I, Campbell G, Lax N, White K, Hanson PS, Lassmann H, Turnbull DM, Mahad, Don J, Ziabreva, Iryna, Campbell, Graham, Lax, Nichola, White, Katherine, Hanson, Peter S, Lassmann, Hans, Turnbull, Douglass M

المصدر: Brain: A Journal of Neurology; May2009, Vol. 132 Issue 5, p1161-1174, 14p

مصطلحات موضوعية: ENZYME inhibitors, ENZYME analysis, PROTEIN analysis, PROTEIN metabolism, BRAIN metabolism, ENZYME metabolism, ANIMALS, AUTOPSY, BRAIN, CELLS, CHRONIC diseases, ELECTRON microscopy, GLUTAMIC acid, IMMUNOHISTOCHEMISTRY, MICE, MITOCHONDRIA, MULTIPLE sclerosis, NEURONS, RESEARCH funding, SPINAL cord, WESTERN immunoblotting

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المؤلفون: Gee LMV; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Barron-Millar B; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Leslie J; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Richardson C; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Zaki MYW; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom; Biochemistry Department, Faculty of Pharmacy, Minia University, Minia, Egypt., Luli S; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Burgoyne RA; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Cameron RIT; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Smith GR; Bioinformatics Support Unit, Newcastle University, Newcastle upon Tyne, United Kingdom., Brain JG; Liver Unit, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Innes B; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Jopson L; Liver Unit, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom., Dyson JK; Liver Unit, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom., McKay KRC; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Pechlivanis A; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom., Holmes E; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom., Berlinguer-Palmini R; Newcastle Bioimaging Unit, Newcastle University, Newcastle upon Tyne, United Kingdom., Victorelli S; Department of Physiology and Biomedical Engineering, Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota., Mells GF; Academic Department of Medical Genetics, University of Cambridge, Cambridge, United Kingdom., Sandford RN; Academic Department of Medical Genetics, University of Cambridge, Cambridge, United Kingdom., Palmer J; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Kirby JA; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Kiourtis C; Cancer Research UK Beatson Institute, Glasgow, United Kingdom., Mokochinski J; MRC London Institute of Medical Sciences, London, United Kingdom., Hall Z; Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, Hammersmith Hospital Campus, London, United Kingdom., Bird TG; Cancer Research UK Beatson Institute, Glasgow, United Kingdom; MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom., Borthwick LA; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Morris CM; Medical Toxicology Centre, Newcastle University, Newcastle upon Tyne, United Kingdom., Hanson PS; Medical Toxicology Centre, Newcastle University, Newcastle upon Tyne, United Kingdom., Jurk D; Department of Physiology and Biomedical Engineering, Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota., Stoll EA; Western Institute for Advanced Study, Denver, Colorado., LeBeau FEN; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Jones DEJ; Liver Unit, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Oakley F; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom. Electronic address: fiona.oakley@newcastle.ac.uk.

المصدر: The American journal of pathology [Am J Pathol] 2023 Jan; Vol. 193 (1), pp. 11-26. Date of Electronic Publication: 2022 Oct 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0370502 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-2191 (Electronic) Linking ISSN: 00029440 NLM ISO Abbreviation: Am J Pathol Subsets: MEDLINE

مواضيع طبية MeSH: Memory, Short-Term* , Cholestasis*/drug therapy, Humans ; Mice ; Animals ; Chenodeoxycholic Acid/pharmacology ; Bile Ducts/surgery ; Liver ; Ligation

المؤلفون: Reynolds WJ; Dermatological Sciences, Translational and Clinical Research Institute Newcastle University Newcastle upon Tyne UK., Bowman A; Dermatological Sciences, Translational and Clinical Research Institute Newcastle University Newcastle upon Tyne UK., Hanson PS; Mental Health Dementia and Neurodegeneration, Translational and Clinical Research Institute Newcastle University Newcastle upon Tyne UK., Critchley A; Royal Victoria Infirmary Newcastle upon Tyne UK., Griffiths B; Royal Victoria Infirmary Newcastle upon Tyne UK., Chavan B; Croda Europe Ltd Snaith UK., Birch-Machin MA; Dermatological Sciences, Translational and Clinical Research Institute Newcastle University Newcastle upon Tyne UK.

المصدر: FASEB bioAdvances [FASEB Bioadv] 2021 Jul 17; Vol. 3 (10), pp. 855-865. Date of Electronic Publication: 2021 Jul 17 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101733210 Publication Model: eCollection Cited Medium: Internet ISSN: 2573-9832 (Electronic) Linking ISSN: 25739832 NLM ISO Abbreviation: FASEB Bioadv Subsets: PubMed not MEDLINE

المؤلفون: Reynolds WJ; Dermatological Sciences, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK., Hanson PS; Campus for Ageing and Vitality, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK., Critchley A; Royal Victoria Infirmary, Newcastle upon Tyne, UK., Griffiths B; Royal Victoria Infirmary, Newcastle upon Tyne, UK., Chavan B; Croda Europe Ltd, Snaith, UK., Birch-Machin MA; Dermatological Sciences, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.

المصدر: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Nov; Vol. 34 (11), pp. 14725-14735. Date of Electronic Publication: 2020 Sep 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

مواضيع طبية MeSH: Fibroblasts/*drug effects , Particulate Matter/*toxicity , Skin Aging/*drug effects, Cells, Cultured ; DNA Breaks, Double-Stranded ; Dermis/cytology ; Fibroblasts/metabolism ; Histones/metabolism ; Humans ; Matrix Metalloproteinases/metabolism ; Particulate Matter/pharmacology ; Receptors, Aryl Hydrocarbon/metabolism ; Transforming Growth Factor beta/metabolism