المؤلفون: Roy Oelen, Dylan H. de Vries, Harm Brugge, M. Grace Gordon, Martijn Vochteloo, single-cell eQTLGen consortium, BIOS Consortium, Chun J. Ye, Harm-Jan Westra, Lude Franke, Monique G. P. van der Wijst

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/a0900e4955844d238d355bfc06a2a975

المؤلفون: Raúl Aguirre-Gamboa, Niek de Klein, Jennifer di Tommaso, Annique Claringbould, Monique GP van der Wijst, Dylan de Vries, Harm Brugge, Roy Oelen, Urmo Võsa, Maria M. Zorro, Xiaojin Chu, Olivier B. Bakker, Zuzanna Borek, Isis Ricaño-Ponce, Patrick Deelen, Cheng-Jiang Xu, Morris Swertz, Iris Jonkers, Sebo Withoff, Irma Joosten, Serena Sanna, Vinod Kumar, Hans J. P. M. Koenen, Leo A. B. Joosten, Mihai G. Netea, Cisca Wijmenga, BIOS Consortium, Lude Franke, Yang Li

المصدر: BMC Bioinformatics, Vol 21, Iss 1, Pp 1-23 (2020)

مصطلحات موضوعية: eQTL, Deconvolution, Cell types, Immune cells, Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12859-020-03576-5; https://doaj.org/toc/1471-2105

URL الوصول: https://doaj.org/article/d968288a4faf422088c9b27830e918ca

المؤلفون: Patrick Deelen, Sipko van Dam, Johanna C. Herkert, Juha M. Karjalainen, Harm Brugge, Kristin M. Abbott, Cleo C. van Diemen, Paul A. van der Zwaag, Erica H. Gerkes, Evelien Zonneveld-Huijssoon, Jelkje J. Boer-Bergsma, Pytrik Folkertsma, Tessa Gillett, K. Joeri van der Velde, Roan Kanninga, Peter C. van den Akker, Sabrina Z. Jan, Edgar T. Hoorntje, Wouter P. te Rijdt, Yvonne J. Vos, Jan D. H. Jongbloed, Conny M. A. van Ravenswaaij-Arts, Richard Sinke, Birgit Sikkema-Raddatz, Wilhelmina S. Kerstjens-Frederikse, Morris A. Swertz, Lude Franke

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/8256eeb26c5746a9a9e8d6dcd1fd68ae

المؤلفون: Monique G. P. van der Wijst, Dylan H. de Vries, Harm Brugge, Harm-Jan Westra, Lude Franke

المصدر: Genome Medicine, Vol 10, Iss 1, Pp 1-15 (2018)

مصطلحات موضوعية: Medicine, Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13073-018-0608-4; https://doaj.org/toc/1756-994X

URL الوصول: https://doaj.org/article/13a7d5fccfb042fcb9fd015eb1ea6184

المؤلفون: Dylan H de Vries, Vasiliki Matzaraki, Olivier B Bakker, Harm Brugge, Harm-Jan Westra, Mihai G Netea, Lude Franke, Vinod Kumar, Monique G P van der Wijst

المصدر: PLoS Pathogens, Vol 16, Iss 4, p e1008408 (2020)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/a3f3e7c46b6e4beeabb740b0209ed87a

المؤلفون: Werna T. Uniken Venema, Pauline Lanting, Michiel Voskuil, Lude Franke, Eleonora A. M. Festen, Shixian Hu, Amber Bangma, Gerard Dijkstra, Harm Brugge, Rinse K. Weersma

المساهمون: Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Translational Immunology Groningen (TRIGR), Stem Cell Aging Leukemia and Lymphoma (SALL), Groningen Institute for Organ Transplantation (GIOT)

المصدر: Alimentary Pharmacology & Therapeutics, 51(11), 1105-1115. Wiley
Alimentary Pharmacology & Therapeutics

مصطلحات موضوعية: Male, Oncology, Pharmacogenomic Variants, Tumour necrosis factor alpha, Inflammatory bowel disease, Biomarkers, Pharmacological, Efficacy of a Pharmacogenetic Passport for Inflammatory Bowel Disease, 0302 clinical medicine, Pharmacology (medical), 030212 general & internal medicine, media_common, Thiopurine methyltransferase, biology, Immunogenicity, Gastroenterology, Middle Aged, Prognosis, Treatment Outcome, Toxicity, Female, Original Article, 030211 gastroenterology & hepatology, Immunosuppressive Agents, Adult, Drug, medicine.medical_specialty, Adolescent, Genotype, Drug-Related Side Effects and Adverse Reactions, media_common.quotation_subject, Young Adult, 03 medical and health sciences, Predictive Value of Tests, Internal medicine, medicine, Humans, Aged, Retrospective Studies, Hepatology, business.industry, Reproducibility of Results, Inflammatory Bowel Diseases, medicine.disease, digestive system diseases, Pharmacogenomic Testing, Pharmacogenetics, Case-Control Studies, biology.protein, Pancreatitis, Transcriptome, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd43e5ca062993462b6002a5c2ce18bf
https://doi.org/10.1111/apt.15762

المؤلفون: Mahmoud Elansary, Knut Krohn, Eleonora Porcu, Julia Dmitrieva, Michel Georges, Harm-Jan Westra, Isabel Alves, Matthias Nauck, Jan H. Veldink, Joost Verlouw, Anette Kalnapenkis, Silva Kasela, Alex W. Hewitt, Roy Oelen, Willem H. Ouwehand, Frank Beutner, Ilkka Seppälä, Yukihide Momozawa, Samuli Ripatti, Brenda W.J.H. Penninx, Patrick Deelen, Michael Stumvoll, Jenny van Dongen, Jonathan K. Pritchard, Roman Kreuzhuber, Marie-Julie Favé, Bernett Lee, Hailang Mei, Biao Zeng, Philip Awadalla, Shuang Li, Kate Downes, Gibran Hemani, Urko M. Marigorta, Anke Tönjes, Morris Swertz, Robert Warmerdam, Joseph E. Powell, Mika Kähönen, Urmo Võsa, Brandon L. Pierce, Benjamin P. Fairfax, Anand Kumar Andiappan, Bastiaan T. Heijmans, Martina Müller-Nurasyid, Sven Bergmann, Katharina Schramm, Hanieh Yaghootkar, Sina Rüeger, Monique G. P. van der Wijst, Lude Franke, Ting Qi, Rick Jansen, Greg Gibson, Cisca Wijmenga, Marc Jan Bonder, Yungil Kim, Viktorija Kukushkina, Johannes Kettunen, Joachim Thiery, Peter A C 't Hoen, Zoltán Kutalik, Jian Yang, Dylan H. de Vries, Olaf Rötzschke, Maarten van Iterson, Peter Kovacs, Peter M. Visscher, Wibowo Arindrarto, Oliver Stegle, Natalia Pervjakova, Julian C. Knight, Tõnu Esko, Annique Claringbould, Lili Milani, Patrick F. Sullivan, Habibul Ahsan, Timothy M. Frayling, Lin Tong, Uwe Völker, Reyhan Sönmez Flitman, Eline Slagboom, Dorret I. Boomsma, Holger Prokisch, Michel G. Nivard, Mawusse Agbessi, Joyce B. J. van Meurs, Alexis Battle, Futao Zhang, Emmanouil T. Dermitzakis, Morris A. Swertz, Grant W. Montgomery, Terho Lehtimäki, Coen D.A. Stehouwer, Jaanika Kronberg, Holger Kirsten, Olli T. Raitakari, Sina A. Gharib, Bruce M. Psaty, Seyhan Yazar, Markus Loeffler, Harm Brugge, Jose Alquicira Hernandez, Mark W. Christiansen, Andrew A. Brown, Markus Perola, Markus Scholz, Ashis Saha, Alexander Teumer

المساهمون: Psychiatry, APH - Mental Health, Amsterdam Neuroscience - Complex Trait Genetics, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, APH - Digital Health, Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Stem Cell Aging Leukemia and Lymphoma (SALL), BIOS Consortium, i2QTL Consortium, 't Hoen, PAC, van Meurs, J., van Dongen, J., van Iterson, M., Swertz, M.A., Jan Bonder, M., Biological Psychology, APH - Personalized Medicine, APH - Methodology, Internal Medicine, Interne Geneeskunde, MUMC+: HVC Pieken Maastricht Studie (9), MUMC+: MA Interne Geneeskunde (3), MUMC+: MA Med Staf Artsass Interne Geneeskunde (9), RS: Carim - V01 Vascular complications of diabetes and metabolic syndrome

المصدر: Nature Genetics, 53(9), 1300-1310. Nature Publishing Group
Võsa, U, Jansen, R, Nivard, M G, van Dongen, J, Boomsma, D I, Franke, L, BIOS Consortium & i2QTL Consortium 2021, ' Large-scale cis-and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression ', Nature genetics, vol. 53, no. 9, pp. 1300-1310 . https://doi.org/10.1038/s41588-021-00913-z
Nature Genetics, 53(9), 1300-+. NATURE PORTFOLIO
BIOS Consortium & i2QTL Consortium 2021, ' Large-scale cis-and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression ', Nature Genetics, vol. 53, no. 9, pp. 1300-1310 . https://doi.org/10.1038/s41588-021-00913-z
Nature Genetics
Nature genetics, vol. 53, no. 9, pp. 1300-1310
Nature Genetics, 53, 1300-1310
Nature Genetics, 53, pp. 1300-1310
Nature genetics, 53(9), 1300-1310. Nature Publishing Group

مصطلحات موضوعية: DISORDER, Multifactorial Inheritance, Quantitative Trait Loci, Genome-wide association study, Quantitative trait locus, Biology, Polymorphism, Single Nucleotide, Gene Expression Regulation/genetics, DISEASE, LINKS, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, All institutes and research themes of the Radboud University Medical Center, RELEVANCE, Blood Proteins/genetics, Gene expression, Genetics, Humans, GENOME-WIDE ASSOCIATION, Polymorphism, Gene, Multifactorial Inheritance/genetics, 030304 developmental biology, Regulation of gene expression, RISK, 0303 health sciences, ARCHITECTURE, Blood Proteins, Transcriptome/genetics, Polymorphism, Single Nucleotide/genetics, Phenotype, SERINE BIOSYNTHESIS, HUMAN TRANSCRIPTOME, DEFICIENCY, Gene Expression Regulation, Expression quantitative trait loci, genome-wide association studies, gene expression, gene regulation, Quantitative Trait Loci/genetics, Nanomedicine Radboud Institute for Molecular Life Sciences [Radboudumc 19], Single Nucleotide/genetics, 030217 neurology & neurosurgery, Genome-Wide Association Study

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b95e9d7b4e1b22eefe3d319e4309b3
https://research.vumc.nl/en/publications/aa2bf4d5-4683-416c-af37-5560d637ebca

المؤلفون: Roy, Oelen, Dylan H, de Vries, Harm, Brugge, M Grace, Gordon, Martijn, Vochteloo, Chun J, Ye, Harm-Jan, Westra, Lude, Franke, Monique G P, van der Wijst

المصدر: Nature communications. 13(1)

مصطلحات موضوعية: Gene Expression Regulation, Receptors, Mitogen, Leukocytes, Mononuclear, Humans, Lupus Erythematosus, Systemic, RNA, Lectins, C-Type, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::81a4355a6281e4e9f9c7207bea4dbdbf
https://pubmed.ncbi.nlm.nih.gov/35672358

المؤلفون: Harm-Jan Westra, van der Wijst Mg, Lude Franke, Harm Brugge, de Vries Dh, Roy Oelen, G. Gordon, Vochteloo M, Ye Cj

مصطلحات موضوعية: Genetics, Regulation of gene expression, Immune system, Gene expression, Expression quantitative trait loci, Context (language use), Biology, Peripheral blood mononuclear cell, Gene, Transcription factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::11ad143e5eadcef63004973c7565d12b
https://doi.org/10.1101/2021.06.04.447088

المؤلفون: Sebo Withoff, Cisca Wijmenga, Xiaojin Chu, Patrick Deelen, Roy Oelen, Irma Joosten, Olivier B. Bakker, Annique Claringbould, Yang Li, Mihai G. Netea, Jennifer di Tommaso, Iris Jonkers, Vinod Kumar, Morris A. Swertz, Monique G. P. van der Wijst, Maria M. Zorro, Zuzanna Borek, Serena Sanna, Isis Ricaño-Ponce, Dylan H. de Vries, Lude Franke, Hans J. P. M. Koenen, Harm Brugge, Cheng-Jian Xu, Raul Aguirre-Gamboa, Niek de Klein, Urmo Võsa, Leo A. B. Joosten

المساهمون: HZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany., Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Molecular Neuroscience and Ageing Research (MOLAR), Stem Cell Aging Leukemia and Lymphoma (SALL)

المصدر: BMC bioinformatics
England
Bmc Bioinformatics, 21(1):243. BioMed Central Ltd.
BMC Bioinformatics
BMC Bioinformatics, 21, 1
BMC Bioinformatics, 21
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-23 (2020)

مصطلحات موضوعية: Cell type, Population, Cell, Quantitative Trait Loci, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Context (language use), Computational biology, Deconvolution, FORMAT, Biology, Quantitative trait locus, lcsh:Computer applications to medicine. Medical informatics, eQTL, Biochemistry, Whole-Body Counting, 03 medical and health sciences, 0302 clinical medicine, Structural Biology, DRIVERS, medicine, Humans, Allele, education, Molecular Biology, lcsh:QH301-705.5, 030304 developmental biology, Whole blood, 0303 health sciences, education.field_of_study, Applied Mathematics, Methodology Article, Immune cells, ASSOCIATION, Cell types, Computer Science Applications, 3. Good health, medicine.anatomical_structure, lcsh:Biology (General), Expression quantitative trait loci, SURVIVAL, lcsh:R858-859.7, DNA microarray, 030217 neurology & neurosurgery, Inflammatory diseases Radboud Institute for Molecular Life Sciences [Radboudumc 5], Genome-Wide Association Study

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28c682c53dee8c14d4e424a1a4efe58
https://doi.org/10.1101/548669