المؤلفون: Elina T. L’Estrade, Hanne D. Hansen, Christina Falk-Petersen, Anne Haugaard, Nane Griem-Krey, Sascha Jung, Hartmut Lüddens, Tanja Schirmeister, Maria Erlandsson, Tomas Ohlsson, Gitte M. Knudsen, Matthias M. Herth, Petrine Wellendorph, Bente Frølund

المصدر: ACS Omega, Vol 4, Iss 5, Pp 8846-8851 (2019)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2470-1343

URL الوصول: https://doaj.org/article/bd6775d756734cf4926d9d3fcbed21d7

المؤلفون: Elli Leppä, Anni-Maija Tuulikki Linden, M. Isabel Aller, Peer Wulff, Olga Vekovischeva, Bernhard Lüscher, Hartmut Lüddens, William Wisden, Esa R Korpi

المصدر: Frontiers in Pharmacology, Vol 7 (2016)

مصطلحات موضوعية: Cerebellum, Purkinje Cells, Neurosteroids, extrasynaptic GABAA receptors, motor performance, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00403/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/99d976fd8ef64a769f0f9c05c1069500

المؤلفون: Alexander Kurz, Kay L Double, Isabel Lastres-Becker, Alessandro Tozzi, Michela Tantucci, Vanessa Bockhart, Michael Bonin, Moisés García-Arencibia, Silke Nuber, Falk Schlaudraff, Birgit Liss, Javier Fernández-Ruiz, Manfred Gerlach, Ullrich Wüllner, Hartmut Lüddens, Paolo Calabresi, Georg Auburger, Suzana Gispert

المصدر: PLoS ONE, Vol 5, Iss 7, p e11464 (2010)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC2898885?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/b6ce765afe504216b978f3c54973d10a

المؤلفون: Salla Mansikkamäki, Saku T. Sinkkonen, Esa R. Korpi, Hartmut Lüddens

المساهمون: Department of Pharmacology, University of Helsinki, Faculty of Medicine, Korva-, nenä- ja kurkkutautien klinikka, HUS Head and Neck Center, Clinicum, Department of Ophthalmology and Otorhinolaryngology, Esa Risto Korpi / Principal Investigator

المصدر: European Journal of Pharmacology. 853:247-255

مصطلحات موضوعية: MECHANISM, 0301 basic medicine, NSAID drugs, Mefenamic acid, Allosteric regulation, Pharmacology, BINDING-SITES, GABA, 03 medical and health sciences, 0302 clinical medicine, Tolfenamic acid, Niflumic acid, medicine, SHIFT, MODULATION, Receptor, Xenopus oocytes, AGENT, Chemistry, GABAA receptor, ANION GRADIENT, A RECEPTORS, SUBUNITS, 3. Good health, Meclofenamic acid, Fenamates, 030104 developmental biology, Flufenamic acid, 317 Pharmacy, ACID, Autoradiography, 030217 neurology & neurosurgery, Recombinant GABA(A) receptors, RESPONSES, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a594845510fd20127f84d7e55226c2
https://doi.org/10.1016/j.ejphar.2019.03.039

المؤلفون: Sascha Jung, Petrine Wellendorph, Gitte M. Knudsen, Anne S. Haugaard, Elina T. L’Estrade, Christina Birkedahl Falk-Petersen, Bente Frølund, Matthias M. Herth, Nane Griem-Krey, Tomas Ohlsson, Maria Erlandsson, Hartmut Lüddens, Tanja Schirmeister, Hanne D. Hansen

المصدر: ACS Omega, Vol 4, Iss 5, Pp 8846-8851 (2019)
L'Estrade, E T, Hansen, H D, Falk-Petersen, C, Haugaard, A, Griem-Krey, N, Jung, S, Lueddens, H, Schirmeister, T, Erlandsson, M, Ohlsson, T, Knudsen, G M, Herth, M M, Wellendorph, P & Frolund, B 2019, ' Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors ', ACS Omega, vol. 4, no. 5, pp. 8846-8851 . https://doi.org/10.1021/acsomega.9b00434

مصطلحات موضوعية: GABAA receptor, Stereochemistry, General Chemical Engineering, General Chemistry, Aminobutyric acid, Imaging agent, lcsh:Chemistry, chemistry.chemical_compound, lcsh:QD1-999, chemistry, Radioligand, Penetrant (biochemical), Benzamide, Receptor, Preclinical imaging

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e74f11686ca51dc163709601bff82f
https://doi.org/10.1021/acsomega.9b00434

المؤلفون: Salla, Mansikkamäki, Saku T, Sinkkonen, Esa R, Korpi, Hartmut, Lüddens

المصدر: European journal of pharmacology. 853

مصطلحات موضوعية: Male, Fenamates, Anti-Inflammatory Agents, Non-Steroidal, Animals, Receptors, GABA-A, Electrophysiological Phenomena, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::749ed07eaac524657f5f20581d5eba8d
https://pubmed.ncbi.nlm.nih.gov/30930251

المؤلفون: Marjorie C. Gondré-Lewis, Kaitlin T. Warnock, Hong Wang, Harry L. June, Kimberly A. Bell, Holger Rabe, Veera Venkata Naga Phani Babu Tiruveedhula, James Cook, Hartmut Lüddens, Laure Aurelian

المصدر: Stress. 19:235-247

مصطلحات موضوعية: Male, 0301 basic medicine, Corticotropin-Releasing Hormone, Physiology, Self Administration, Rats, Sprague-Dawley, Behavioral Neuroscience, 0302 clinical medicine, GABA receptor, Risk Factors, Antalarmin, Prefrontal cortex, GABAA receptor, Maternal Deprivation, Amygdala, Vitamin B 12, Psychiatry and Mental health, Neuropsychology and Physiological Psychology, medicine.anatomical_structure, Female, medicine.symptom, Psychology, medicine.drug, Clinical psychology, medicine.medical_specialty, Alcohol Drinking, medicine.drug_class, Prefrontal Cortex, Binge drinking, Impulsivity, Receptors, Corticotropin-Releasing Hormone, Article, 03 medical and health sciences, Internal medicine, medicine, Animals, Pyrroles, Benzodiazepine, Ethanol, Endocrine and Autonomic Systems, Receptors, GABA-A, Rats, Pyrimidines, 030104 developmental biology, Endocrinology, Impulsive Behavior, Conditioning, Operant, Stress, Psychological, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3088d497f3400b83dbd590afd137cf
https://doi.org/10.3109/10253890.2016.1160280

المؤلفون: Hartmut Lüddens, Helen Damerow, Judith Weber, Bente Frølund, Annika Kretzschmann, Sascha Jung, Frank Rösch, Markus Piel, Kirsten Yakoub, Anne S. Haugaard, Tanja Schirmeister, Aylin Sibel Cankaya, Christian Sattler

المصدر: Journal of medicinal chemistry. 61(5)

مصطلحات موضوعية: 0301 basic medicine, Imidazopyridine, Stereochemistry, Pyridines, Protein subunit, Aminobutyric acid, law.invention, 03 medical and health sciences, chemistry.chemical_compound, Inhibitory Concentration 50, Structure-Activity Relationship, 0302 clinical medicine, law, Drug Discovery, Structure–activity relationship, Humans, GABA-A Receptor Antagonists, Receptor, Benzamide, GABAA receptor, Chemistry, Imidazoles, Receptors, GABA-A, Protein Subunits, 030104 developmental biology, Recombinant DNA, Molecular Medicine, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb711a1fb0d60f1f548b1a7b9ac0c584
https://pubmed.ncbi.nlm.nih.gov/29451785

المؤلفون: Julia Heim, Sacarin Bunbanjerdsuk, Lea Zografidou, Simone Katharina Becker, Haralampos Gouveris, Hartmut Lüddens, Nadine Wiesmann, Anna-Maria Meierl, Jürgen Brieger, Franz H. Grus, Judith Strozynski

المصدر: Journal of Proteomics. 113:154-161

مصطلحات موضوعية: Proteomics, Biophysics, Biology, Biochemistry, Cellular protein, Immunocytochemical staining, Heterogeneous-Nuclear Ribonucleoprotein K, Cell Movement, Cell Line, Tumor, medicine, Humans, Irradiation, Neoplasm Metastasis, Endoplasmic Reticulum Chaperone BiP, medicine.disease, Molecular biology, Head and neck squamous-cell carcinoma, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Blot, Ribonucleoproteins, Gamma Rays, Head and Neck Neoplasms, Biological significance, Cell culture, Carcinoma, Squamous Cell, Cancer research

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1aad9b33879bcfae84a6afe63bc4fa5
https://doi.org/10.1016/j.jprot.2014.09.017

المؤلفون: Markus Hartmann, Daniel Flesch, Astrid Kaiser, Pascal Heitel, Jan S. Kramer, Hartmut Lüddens, Sun-Yee Cheung, Manfred Schubert-Zsilavecz, Mario Wurglics, Jan Heering, Daniel Merk, Ewgenij Proschak, Jurema Schmidt, Matthias Gabler, Kerstin Lüddens-Dämgen, Mara Lindner, Christina Lamers

المساهمون: Publica

المصدر: Journal of medicinal chemistry. 60(16)

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.drug_class, Pyridines, Peroxisome proliferator-activated receptor, Receptors, Cytoplasmic and Nuclear, ATP-binding cassette transporter, Cholesterol 7 alpha-hydroxylase, 01 natural sciences, Rats, Sprague-Dawley, 03 medical and health sciences, Structure-Activity Relationship, Drug Stability, Drug Discovery, medicine, Glucose homeostasis, Animals, Humans, PPAR alpha, Receptor, Cholesterol 7-alpha-Hydroxylase, ATP Binding Cassette Transporter, Subfamily B, Member 11, chemistry.chemical_classification, Bile acid, 010405 organic chemistry, Chemistry, HEK 293 cells, Imidazoles, Membrane Transport Proteins, Hep G2 Cells, 0104 chemical sciences, Molecular Docking Simulation, Zolpidem, 030104 developmental biology, HEK293 Cells, Biochemistry, Molecular Medicine, Farnesoid X receptor, ATP-Binding Cassette Transporters, Sterol Regulatory Element Binding Protein 1, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a37a7cec6385e5a7b8e632cd9410315
https://pubmed.ncbi.nlm.nih.gov/28749691