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1دورية أكاديمية
المؤلفون: Anders Friberg, Hartmut Rehwinkel, Duy Nguyen, Vera Pütter, Maria Quanz, Jörg Weiske, Uwe Eberspächer, Iring Heisler, Gernot Langer
المصدر: ACS Omega, Vol 5, Iss 22, Pp 13034-13041 (2020)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2470-1343
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2
المؤلفون: Judith Günther, Roman C. Hillig, Katja Zimmermann, Stefan Kaulfuss, Clara Lemos, Duy Nguyen, Hartmut Rehwinkel, Matthew Habgood, Christian Lechner, Roland Neuhaus, Ursula Ganzer, Mark Drewes, Jijie Chai, Léa Bouché
المصدر: Journal of Medicinal Chemistry. 65:14366-14390
مصطلحات موضوعية: Drug Discovery, Molecular Medicine, Keto Acids, Transaminases, Amino Acids, Branched-Chain
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3
المؤلفون: Benjamin Bader, Sabine Zitzmann-Kolbe, Carl Friedrich Nising, Ulrich Lücking, Qi Wang, Hartmut Rehwinkel, Florian Bartels, Qiuwen Wang, Markus Berger, Antje Margret Wengner, Lars Wortmann, Dieter Moosmayer, Philipp Buchgraber, Hans Briem, Dominik Mumberg, Knut Eis, Uwe Eberspächer, Stefanie Hammer, Christoph A. Schatz, Gerhard Siemeister, Philip Lienau, Ulf Bömer
المصدر: Journal of Medicinal Chemistry. 64:12723-12737
مصطلحات موضوعية: DNA repair, Cell, Antineoplastic Agents, DNA-Activated Protein Kinase, Cell cycle phase, Mice, Phosphatidylinositol 3-Kinases, Structure-Activity Relationship, chemistry.chemical_compound, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Protein kinase A, Cell Proliferation, Molecular Structure, Chemistry, TOR Serine-Threonine Kinases, Drug Synergism, medicine.disease, Xenograft Model Antitumor Assays, In vitro, Rats, medicine.anatomical_structure, Gene Expression Regulation, Ataxia-telangiectasia, Hepatocytes, Cancer research, Molecular Medicine, Drug Therapy, Combination, Homologous recombination, DNA
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4
المؤلفون: Markus Berger, Heike Schäcke, Hartmut Rehwinkel, Stefan Jaroch, Ekkehard May, Roland Neuhaus, Thomas M. Zollner, Antje Rottmann
المصدر: Bioorganicmedicinal chemistry letters. 30(16)
مصطلحات موضوعية: Agonist, Male, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, 01 natural sciences, Biochemistry, Transactivation, Structure-Activity Relationship, Glucocorticoid receptor, Dogs, Receptors, Glucocorticoid, Psoriasis, Drug Discovery, medicine, Animals, Structural motif, Molecular Biology, Transrepression, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, Anti-Inflammatory Agents, Non-Steroidal, medicine.disease, In vitro, 0104 chemical sciences, Rats, 010404 medicinal & biomolecular chemistry, Hepatocytes, Molecular Medicine, Female, Glucocorticoid, medicine.drug
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5
المؤلفون: Andreas Unterberg, Hartmut Rehwinkel, Ann Christin Beck, Felix Sahm, Michael Platten, Daniel Schrimpf, Stefan Kaulfuss, Wolfgang Wick, Olaf Panknin, Holger Hess-Stumpp, Roland Neuhaus, Roman C. Hillig, Judith Guenther, David Capper, Andrea Haegebart, Luisella Toschi, Markus Bauser, Stefan Pusch, Manfred Jugold, Martina Ott, Christel Herold-Mende, Katja Zimmermann, Jörg Balss, Jessica Eisel, Sonja Krausert, Viktoria Eichwald, Viktoria Fischer, Andreas von Deimling
المصدر: Acta Neuropathologica. 133:629-644
مصطلحات موضوعية: 0301 basic medicine, IDH1, Cell Survival, Mutant, Mice, Nude, Antineoplastic Agents, Astrocytoma, Biology, medicine.disease_cause, Pathology and Forensic Medicine, Glutarates, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Pan-Mutant-IDH1 Inhibitor Bay-1436032, In vivo, Cell Line, Tumor, Escherichia coli, Sf9 Cells, medicine, Animals, Humans, Enzyme Inhibitors, Mice, Inbred BALB C, Mutation, Aniline Compounds, Brain Neoplasms, Myeloid leukemia, Sarcoma, Xenograft Model Antitumor Assays, Molecular biology, Isocitrate Dehydrogenase, Recombinant Proteins, In vitro, HEK293 Cells, 030104 developmental biology, Isocitrate dehydrogenase, 030220 oncology & carcinogenesis, Colonic Neoplasms, Benzimidazoles, Female, Neurology (clinical)
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6
المؤلفون: Matthew Dearman, Markus Berger, Ramon Hendrickx, Hartmut Rehwinkel, Anders Eriksson, Matti Lepistö, Thomas Hansson, Lisa Wissler, Karl Edman, Martin Hemmerling, Jan Dahmén, Tina Jellesmark Jensen, Svetlana Ivanova
المصدر: Bioorganic & Medicinal Chemistry Letters. 26:5741-5748
مصطلحات موضوعية: Indazoles, Steroid hormone receptor binding, Clinical Biochemistry, Pharmaceutical Science, Inflammation, Ether, Pharmacology, 010402 general chemistry, 01 natural sciences, Biochemistry, Peripheral blood mononuclear cell, chemistry.chemical_compound, Receptors, Glucocorticoid, Glucocorticoid receptor, Oral administration, Drug Discovery, medicine, Animals, Humans, Molecular Biology, Cells, Cultured, Indazole, Tumor Necrosis Factor-alpha, 010405 organic chemistry, Anti-Inflammatory Agents, Non-Steroidal, Organic Chemistry, Rats, 0104 chemical sciences, Molecular Docking Simulation, chemistry, Leukocytes, Mononuclear, Molecular Medicine, Joints, Tumor necrosis factor alpha, medicine.symptom, Ethers
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7
المؤلفون: Arwed Cleve, Bernd Buchmann, Iring Heisler, Thomas Müller, Hartmut Rehwinkel, Roland Neuhaus, Marcus Bauser, Holger Siebeneicher
المصدر: Chemmedchem
مصطلحات موضوعية: 0301 basic medicine, Administration, Oral, Biological Availability, GLUT1 inhibitors, Biology, Biochemistry, quinoline carboxamides, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, medicinal chemistry, Drug Discovery, Humans, Structure–activity relationship, General Pharmacology, Toxicology and Pharmaceutics, Pharmacology, Glucose Transporter Type 1, Molecular Structure, Full Paper, Organic Chemistry, Glucose transporter, Transporter, Full Papers, Small molecule, Warburg effect, High-Throughput Screening Assays, 030104 developmental biology, 030220 oncology & carcinogenesis, Quinolines, biology.protein, Pyrazoles, Molecular Medicine, GLUT2, structure–activity relationships, GLUT3
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8
المؤلفون: Markus Berger, Ramon Hendrickx, Martin Lindsjö, Stinabritt Nilsson, Tina Jellesmark Jensen, Tomas Klingstedt, Wayne Russell, Hartmut Rehwinkel, Martin Hemmerling, Thomas Hansson, Nafizal Hossain, Stefan Eirefelt, Balint Gabos, Henrik Johansson, Grigorios Nikitidis, Svetlana Ivanova, John Steele, Matti Lepistö, Eskil Johnsson, Anne-Helene Jansson, Anna Abrahamsson, Carina Kärrman Mårdh, Krister Henriksson, Jan Dahmén, Karl Edman, Anders Eriksson, Ulrika Tehler, Anders Jerre, Irene Mile, Lisa Wissler
المصدر: Journal of medicinal chemistry. 60(20)
مصطلحات موضوعية: 0301 basic medicine, Drug, medicine.medical_specialty, Indazoles, medicine.drug_class, media_common.quotation_subject, Proton Magnetic Resonance Spectroscopy, Pulmonary Edema, Pharmacology, Fluticasone propionate, Mass Spectrometry, 03 medical and health sciences, Glucocorticoid receptor, Therapeutic index, Receptors, Glucocorticoid, Internal medicine, Drug Discovery, Acetamides, Administration, Inhalation, medicine, Animals, Humans, Receptor, media_common, Aged, Thymic involution, Inhalation, Dose-Response Relationship, Drug, Chemistry, Rats, 030104 developmental biology, Endocrinology, Molecular Medicine, Corticosteroid, Powders, medicine.drug
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9
المؤلفون: Lisa Wissler, Stefan Jaroch, Norbert Schmees, Andreas Reichel, Heike Schäcke, Hartmut Rehwinkel, Markus Berger, Karl Edman
المصدر: Bioorganicmedicinal chemistry letters. 27(3)
مصطلحات موضوعية: 0301 basic medicine, Agonist, Transcriptional Activation, Tetrahydronaphthalenes, medicine.drug_class, Clinical Biochemistry, Anti-Inflammatory Agents, Pharmaceutical Science, Biochemistry, DNA-binding protein, Monocytes, 03 medical and health sciences, Transactivation, Inhibitory Concentration 50, Structure-Activity Relationship, 0302 clinical medicine, Glucocorticoid receptor, Receptors, Glucocorticoid, Genes, Reporter, Drug Discovery, medicine, Humans, Molecular Biology, Transrepression, Binding Sites, Chemistry, Organic Chemistry, Hydrogen Bonding, Amino Alcohols, In vitro, Molecular Docking Simulation, 030104 developmental biology, 030220 oncology & carcinogenesis, Nuclear receptor coactivator 2, Microsomes, Liver, Molecular Medicine, Glucocorticoid, medicine.drug, Half-Life, HeLa Cells, Protein Binding
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10
المؤلفون: Marcus Bauser, Hartmut Rehwinkel, Bernd Buchmann, Thomas Müller, Ludwig Zorn, Iring Heisler, Roland Neuhaus, Holger Siebeneicher, Joachim Telser
المصدر: Bioorganicmedicinal chemistry letters. 26(7)
مصطلحات موضوعية: 0301 basic medicine, Male, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Pyrazolopyrimidine, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, 0302 clinical medicine, In vivo, Drug Discovery, Structure–activity relationship, Animals, Humans, Rats, Wistar, Molecular Biology, Glucose Transporter Type 1, biology, Organic Chemistry, Glucose transporter, Piperazine, 030104 developmental biology, Pyrimidines, chemistry, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, GLUT2, GLUT1