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المؤلفون: Al-Wahaibi LH; Department of Chemistry, College of Sciences, Princess Nourah Bint Abdulrahman University, Riyadh 11564, Saudi Arabia., Hisham M; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Deraya University, Universities Zone, New Minia City 61111, Egypt., Abou-Zied HA; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Deraya University, Universities Zone, New Minia City 61111, Egypt., Hassan HA; Medicinal Chemistry Department, Faculty of Pharmacy, Minia University, Minia 61519, Egypt., Youssif BGM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt., Bräse S; Institute of Biological and Chemical Systems, IBCS-FMS, Karlsruhe Institute of Technology, 76131 Karlsruhe, Germany., Hayallah AM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Sphinx University, Assiut 71515, Egypt., Abdel-Aziz M; Medicinal Chemistry Department, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.

المصدر: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2023 Oct 26; Vol. 16 (11). Date of Electronic Publication: 2023 Oct 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101238453 Publication Model: Electronic Cited Medium: Print ISSN: 1424-8247 (Print) Linking ISSN: 14248247 NLM ISO Abbreviation: Pharmaceuticals (Basel) Subsets: PubMed not MEDLINE

المؤلفون: Al-Wahaibi LH; Department of Chemistry, College of Sciences, Princess Nourah bint Abdulrahman University, Riyadh 11564, Saudi Arabia., Abou-Zied HA; Medicinal Chemistry Department, Faculty of Pharmacy, Deraya University, Minia 61111, Egypt., Hisham M; Medicinal Chemistry Department, Faculty of Pharmacy, Deraya University, Minia 61111, Egypt., Beshr EAM; Medicinal Chemistry Department, Faculty of Pharmacy, Minia University, Minia 61519, Egypt., Youssif BGM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt., Bräse S; Institute of Biological and Chemical Systems, IBCS-FMS, Karlsruhe Institute of Technology, 76131 Karlsruhe, Germany., Hayallah AM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Sphinx University, Assiut 71515, Egypt., Abdel-Aziz M; Medicinal Chemistry Department, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2023 Sep 12; Vol. 28 (18). Date of Electronic Publication: 2023 Sep 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/pharmacology , Neoplasms*, Humans ; Structure-Activity Relationship ; Proto-Oncogene Proteins B-raf ; Molecular Docking Simulation ; Cell Proliferation ; ErbB Receptors/metabolism ; Drug Screening Assays, Antitumor ; Cell Line, Tumor ; Protein Kinase Inhibitors/pharmacology

المؤلفون: Mohammed HHH; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt. hamada.hashem@pharm.sohag.edu.eg.; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt. hamada.hashem@pharm.sohag.edu.eg.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Deraya University, New Minia City, 61768, Egypt. hamada.hashem@pharm.sohag.edu.eg., Ali DME; Department of Biochemistry, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt., Badr M; Department of Biochemistry, Faculty of Pharmacy, Menoufia University, Menoufia, Egypt., Habib AGK; Department of Biotechnology and Life Sciences, Faculty of Postgraduate Studies for Advanced Sciences, Beni-Suef University, Beni-Suef, Egypt., Mahmoud AM; Department of Microbiology and Immunology, Faculty of Pharmacy, Deraya University, New Minia City, 61768, Egypt., Farhan SM; Department of Microbiology and Immunology, Faculty of Pharmacy, Deraya University, New Minia City, 61768, Egypt., Gany SSHAE; Department of Microbiology and Immunology, Faculty of Pharmacy, Deraya University, New Minia City, 61768, Egypt., Mohamad SA; Department of Pharmaceutics and Clinical Pharmacy, Faculty of Pharmacy, Deraya University, New Minia, Minya, 61768, Egypt., Hayallah AM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, El Fateh, 71526, Egypt.; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Sphinx University, New Assiut, Egypt., Abbas SH; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt., Abuo-Rahma GEA; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt. gamal.aborahama@mu.edu.eg.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Deraya University, New Minia City, 61768, Egypt. gamal.aborahama@mu.edu.eg.

المصدر: Molecular diversity [Mol Divers] 2023 Aug; Vol. 27 (4), pp. 1751-1765. Date of Electronic Publication: 2022 Sep 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

مواضيع طبية MeSH: Ciprofloxacin*/pharmacology , Ciprofloxacin*/chemistry , Anti-Infective Agents*/pharmacology, Topoisomerase II Inhibitors/pharmacology ; Topoisomerase II Inhibitors/chemistry ; Molecular Docking Simulation ; DNA Gyrase/chemistry ; DNA Gyrase/metabolism ; Escherichia coli ; Staphylococcus aureus ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Microbial Sensitivity Tests ; Structure-Activity Relationship ; Molecular Structure

المؤلفون: Al-Wahaibi LH; Department of Chemistry, College of Sciences, Princess Nourah bint Abdulrahman University, Riyadh 11564, Saudi Arabia., Abou-Zied HA; Medicinal Chemistry Department, Faculty of Pharmacy, Deraya University, Minia 61111, Egypt., Beshr EAM; Medicinal Chemistry Department, Faculty of Pharmacy, Minia University, Minia 61519, Egypt., Youssif BGM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt., Hayallah AM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Sphinx University, Assiut 71515, Egypt., Abdel-Aziz M; Medicinal Chemistry Department, Faculty of Pharmacy, Deraya University, Minia 61111, Egypt.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 May 22; Vol. 24 (10). Date of Electronic Publication: 2023 May 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Cell Proliferation*/drug effects , Density Functional Theory* , Drug Design* , ErbB Receptors*/antagonists & inhibitors , Proto-Oncogene Proteins B-raf*/antagonists & inhibitors , Pyrazoles*/chemical synthesis , Pyrazoles*/chemistry , Pyrazoles*/pharmacokinetics , Pyrazoles*/pharmacology , Pyrazoles*/toxicity , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/pharmacokinetics , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/toxicity, Humans ; Apoptosis/drug effects ; Cell Line ; Cell Survival/drug effects ; Molecular Docking Simulation ; Static Electricity ; Structure-Activity Relationship

المؤلفون: Abou-Zied HA; Medicinal Chemistry Department, Faculty of Pharmacy, Deraya University, Minia, Egypt., Beshr EAM; Medicinal Chemistry Department, Faculty of Pharmacy, Minia University, Minia, Egypt., Gomaa HAM; Pharmacology Department, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia., Mostafa YA; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, Egypt., Youssif BGM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, Egypt., Hayallah AM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, Egypt.; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Sphinx University, Assiut, Egypt., Abdel-Aziz M; Medicinal Chemistry Department, Faculty of Pharmacy, Minia University, Minia, Egypt.

المصدر: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2023 Apr; Vol. 356 (4), pp. e2200464. Date of Electronic Publication: 2022 Dec 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4184 (Electronic) Linking ISSN: 03656233 NLM ISO Abbreviation: Arch Pharm (Weinheim) Subsets: MEDLINE

مواضيع طبية MeSH: Chalcones*/pharmacology , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry, Humans ; Structure-Activity Relationship ; Erlotinib Hydrochloride/pharmacology ; Cell Line, Tumor ; Molecular Docking Simulation ; Proto-Oncogene Proteins B-raf/genetics ; Proto-Oncogene Proteins B-raf/chemistry ; Cell Proliferation ; ErbB Receptors/metabolism ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/chemistry ; Drug Screening Assays, Antitumor ; Molecular Structure

المؤلفون: Mohammed HHH; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, Egypt.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, Egypt., Abd El-Hafeez AA; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Cancer Biology Department, Pharmacology and Experimental Oncology Unit, National Cancer Institute, Cairo University, Cairo, Egypt., Ebeid K; Department of Pharmaceutics, Faculty of Pharmacy, Minia University, Minia, Egypt.; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA, USA.; Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Manufacturing, Deraya University, New Minia City, Minia, Egypt., Mekkawy AI; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA, USA.; Department of Pharmaceutics and Clinical Pharmacy, Faculty of Pharmacy, Sohag University, Sohag, Egypt., Abourehab MAS; Department of Pharmaceutics, Faculty of Pharmacy, Umm Al Qura University, Makkah, Saudi Arabia., Wafa EI; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA, USA., Alhaj-Suliman SO; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA, USA., Salem AK; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA, USA.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA., Ghosh P; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Department of Medicine, University of California San Diego, La Jolla, CA, USA.; Rebecca and John Moore Comprehensive Cancer Center, University of California San Diego, La Jolla, CA, USA.; Veterans Affairs Medical Center, La Jolla, CA, USA., Abuo-Rahma GEA; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, Egypt.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Deraya University, Minia, Egypt., Hayallah AM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, Egypt.; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Sphinx University, New Assiut, Egypt., Abbas SH; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, Egypt.

المصدر: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 1346-1363.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/metabolism , Antineoplastic Agents*/pharmacology , Chalcone*/pharmacology , Chalcones*/metabolism , Chalcones*/pharmacology, Caco-2 Cells ; Cell Line, Tumor ; Cell Proliferation ; Ciprofloxacin/pharmacology ; DNA Damage ; DNA Topoisomerases, Type I/metabolism ; DNA Topoisomerases, Type II/metabolism ; Doxorubicin/pharmacology ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Polymerization ; Structure-Activity Relationship ; Triazoles/pharmacology ; Tubulin/metabolism

المؤلفون: Abdelgawad MA; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Aljouf 72341, Saudi Arabia., Hayallah AM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Sphinx University, New Assiut 71515, Egypt., Bukhari SNA; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Aljouf 72341, Saudi Arabia., Musa A; Department of Pharmacognosy, College of Pharmacy, Jouf University, Aljouf 72341, Saudi Arabia., Elmowafy M; Department of Pharmaceutics, College of Pharmacy, Jouf University, Aljouf 72341, Saudi Arabia., Abdel-Rahman HM; Medicinal Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Badr University, Assiut 2014101, Egypt., Abd El-Gaber MK; Medicinal Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.

المصدر: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2022 Nov 15; Vol. 15 (11). Date of Electronic Publication: 2022 Nov 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101238453 Publication Model: Electronic Cited Medium: Print ISSN: 1424-8247 (Print) Linking ISSN: 14248247 NLM ISO Abbreviation: Pharmaceuticals (Basel) Subsets: PubMed not MEDLINE