المؤلفون: Myria Nikolaou, Timothy J. Perren, Gia Nemsadze, Richard D. Baird, Robert McEwen, Daniel Stetson, Duncan Wheatley, A.M. Brunt, Hayley Cartwright, Max McLaughlin-Callan, Jean-Marc Ferrero, Peter Schmid, Cheryl Lawrence, Jacinta Abraham, Nicholas C. Turner, László Mangel, Melissa Phillips, Matthew Burgess, Peter Hall, John Conibear, Andrew Foxley, Aaron Prendergast, Kelly Mousa, Robert Stein, Yeon Hee Park, Javier Cortes, Stephen Chan, Elza C. de Bruin, Brian Dougherty

المصدر: Cancer Research. 81:PD1-11

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, education.field_of_study, business.industry, Hazard ratio, Population, Cancer, medicine.disease, Placebo, chemistry.chemical_compound, Breast cancer, Paclitaxel, chemistry, Statistical significance, Internal medicine, medicine, Clinical endpoint, business, education

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a130894bef5287d61428650111815a23
https://doi.org/10.1158/1538-7445.sabcs20-pd1-11

المؤلفون: A.M. Brunt, John Conibear, Aaron Prendergast, Nicholas C. Turner, László Mangel, Robert McEwen, Peter Schmid, Jean-Marc Ferrero, Andrew Foxley, Cheryl Lawrence, Kelly Mousa, Jacinta Abraham, Robert Stein, Gia Nemsadze, Hayley Cartwright, Melissa Phillips, Matthew Burgess, Max McLaughlin-Callan, Brian Dougherty, Shah-Jalal Sarker, Timothy J. Perren, Elza C. de Bruin, Yeon Hee Park, Javier Cortes, Richard D. Baird, Daniel Stetson, Stephen Chan, Duncan Wheatley, Peter Hall

المساهمون: Baird, Richard [0000-0001-7071-6483], Apollo - University of Cambridge Repository

المصدر: Schmid, P, Abraham, J, Chan, S, Wheatley, D, Murray Brunt, A, Nemsadze, G, D. Baird, R, Hee Park, Y, Hall, P S, Perren, T, C. Stein, R, Mangel, L, Ferrero, J-M, Phillips, M, Conibear, J, Cortes, J, Foxley, A, C. de Bruin, E, McEwen, R, Stetson, D, Dougherty, B, Sarker, S-J, Prendergast, A, McLaughlin-Callan, M, Burgess, M, Lawrence, C, Cartwright, H, Mousa, K & C. Turner, N 2020, ' Capivasertib Plus Paclitaxel Versus Placebo Plus Paclitaxel As First-Line Therapy for Metastatic Triple-Negative Breast Cancer: The PAKT Trial ', Journal of Clinical Oncology, vol. 38, no. 5, pp. 423-433 . https://doi.org/10.1200/JCO.19.00368

مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, Cancer Research, medicine.medical_specialty, Paclitaxel, Class I Phosphatidylinositol 3-Kinases, Triple Negative Breast Neoplasms, Q1, Placebos, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Breast cancer, Double-Blind Method, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Medicine, Humans, Pyrroles, Progression-free survival, PI3K/AKT/mTOR pathway, Triple-negative breast cancer, Aged, business.industry, Akt/PKB signaling pathway, PTEN Phosphohydrolase, Middle Aged, medicine.disease, R1, Progression-Free Survival, Clinical trial, 030104 developmental biology, Pyrimidines, chemistry, 030220 oncology & carcinogenesis, Female, business, Proto-Oncogene Proteins c-akt, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6549b60be62c31662c5390c082310711
https://pubmed.ncbi.nlm.nih.gov/31900440

المؤلفون: Peter Sankey, Debra H. Josephs, Anuradha Jayaram, Sandy Beare, Simon J. Crabb, John Staffurth, Joanna C. Burr, Josep Linares, Marian Duggan, Aiman Haider, Moon Chung, Graham M. Wheeler, Mark Linch, Hayley Cartwright, Mahaz Kayani, Anjali Zarkar, Leah Ensell, Colin C. Pritchard, Sergio A. Quezada, Gerhardt Attard, Alex Freeman, Bihani Kularatne, Ayse U. Akarca, John A. Hartley, Laura White, Teresa Marafioti, Robert Jones, Giulia Pellizzari, Yien Ning Sophia Wong

المصدر: Cancer Research. 81:LB004-LB004

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, business.industry, Cancer, Ipilimumab, medicine.disease, Prostate cancer, Internal medicine, Cohort, medicine, Clinical endpoint, Biomarker (medicine), Stage (cooking), Nivolumab, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::014701d8449a3a66588a86e206610d1c
https://doi.org/10.1158/1538-7445.am2021-lb004

المؤلفون: Richard D. Baird, E Copson, S-J Sarker, Robert Stein, Nicholas C. Turner, Peter Schmid, H Kristeleit, E Sims, Steve Chan, Andrew Tutt, Christopher J. Poole, U Bathakur, Timothy J. Perren, Kelly Mousa, Hayley Cartwright, J Bishop, Duncan Wheatley, Jacinta Abraham, Gargi Patel, Catherine Harper-Wynne

المصدر: Cancer Research. 76:OT1-03

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Chemotherapy, Taxane, Akt inhibitor AZD5363, business.industry, medicine.medical_treatment, Cancer, medicine.disease, Metastatic breast cancer, Surgery, chemistry.chemical_compound, Breast cancer, Paclitaxel, chemistry, Internal medicine, medicine, business, PI3K/AKT/mTOR pathway

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::48974cbf5f55f05a51b03f060535a392
https://doi.org/10.1158/1538-7445.sabcs15-ot1-03-13

المؤلفون: Aaron Prendergast, Shah-Jalal Sarker, Nicholas C. Turner, Hayley Cartwright, Jacinta Abraham, Timothy J. Perren, Melissa Phillips, Duncan Wheatley, Peter Schmid, Yeon Hee Park, Peter Hall, Kelly Mousa, Gia Nemsadze, Robert Stein, Murray Brunt, Stephen Chan, John Conibear, Mangel László, Jean-Marc Ferrero, Richard D. Baird

المصدر: Journal of Clinical Oncology. 36:1007-1007

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, business.industry, AKT1, Placebo, medicine.disease, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Breast cancer, Paclitaxel, chemistry, 030220 oncology & carcinogenesis, Internal medicine, Toxicity, Clinical endpoint, Medicine, business, PI3K/AKT/mTOR pathway, Triple-negative breast cancer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::33b7db63f42e2f57ed9b321a8c0e17ac
https://doi.org/10.1200/jco.2018.36.15_suppl.1007