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1دورية أكاديمية
المصدر: Journal of Inflammation Research, Vol Volume 15, Pp 5945-5957 (2022)
مصطلحات موضوعية: background: two novel systemic inflammation indices, sii and siri are associated with increased risk of cardiovascular diseases (cvd). however, sii and siri are prone to change over time and the association between changeable status and long-term outcome risk remains to be uncovered. this study aims to examine the association between the dynamic status of sii and siri and risk of cvd. methods: this prospective study included a total of 45809 subjects without mi, stroke and cancer prior to or in 2010 (baseline of this study). the dynamic status of sii and siri during 2006, 2008, 2010 were assessed by dynamic trajectories (primary exposure), annual increase, and average value. the outcome was cvd incidence during 8.6 years’ follow-up. multiple cox regression models were used to calculate the adjusted hazard ratios (hrs) and confidence intervals (95%cis). results: four dynamic trajectories of sii and siri were identified as follows: low stable pattern, moderate stable pattern, increase pattern, and decrease pattern. for sii, compared with ‘low stable pattern’, after controlling confounders and level of sii in 2006, adjusted hrs were 1.24(95% ci=1.02-1.51) for ‘increase pattern’ and 1.11(95% ci=1.00-1.23) for ‘moderate-stable pattern’ while the association was not significant for ‘decrease pattern’. additionally, the highest group of annual sii increase and average sii had respective hr of 1.20(95% ci=1.05-1.37) and 1.32(95% ci=1.13-1.55). the results were consistent for siri. ‘increase pattern’ and ‘moderate stable pattern’ increased the risk of cvd by 38%(hr=1.38, 95% ci=1.17-1.63) and 12% (hr=1.12, 95% ci=1.01-1.25) while no significant association was found for ‘decrease pattern’. the highest group of annual siri increase and average siri had respective hr of 1.25(95% ci=1.09-1.44) and 1.39(95% ci=1.19-1.63). conclusion: dynamic status of sii and siri was significantly associated with risk of cvd, which highlighted that we should focus on the dynamic change of sii and siri., Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: de Cosio, Federico GerardoAff1, Aff5, Diaz-Apodaca, Beatriz, Baker, Amanda, Cifuentes, Miriam Patricia, Ojeda-Casares, Hector, Constandce, Daniel, Becerra, Francisco
المصدر: SN Comprehensive Clinical Medicine. 3(6):1334-1343
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3دورية أكاديمية
المؤلفون: Fei-Yan He, Gang Chen, Rong-quan He, Zhi-Guang Huang, Jian-Di Li, Wei-Zi Wu, Ji-Tian Chen, Yu-Lu Tang, Dong-Ming Li, Shang-Ling Pan, Zhen-Bo Feng, Yi-wu Dang
المصدر: PeerJ, Vol 10, p e12944 (2022)
مصطلحات موضوعية: Immediate early response 3 (IER3), Hepatocellular carcinoma (HCC), Immunohistochemistry, Gene chip, RNA-sequencing, Hazard ratios (HRs), Medicine, Biology (General), QH301-705.5
وصف الملف: electronic resource
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4
المؤلفون: Amanda Baker, Miriam Patricia Cifuentes, Federico Gerardo de Cosio, Hector Ojeda-Casares, Francisco Becerra, Beatriz A. Díaz-Apodaca, Daniel Constandce
المصدر: Sn Comprehensive Clinical Medicine
مصطلحات موضوعية: business.industry, Proportional hazards model, Diabetes, Hazard ratio, 030209 endocrinology & metabolism, Hazard ratios (HRs), Predictor variables, Disease, Cardiovascular disease, medicine.disease, Time to death, Obesity, Chronic respiratory disease, 03 medical and health sciences, 0302 clinical medicine, Diabetes mellitus, Medicine, 030212 general & internal medicine, business, Mortality trends, Demography
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5دورية أكاديمية
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