المؤلفون: Joel M. Harris, Xiaoping Zhou, John A. Morrow, Sue-Ing Lin, Marco A. S. Baptista, John M. Sanders, Xiaoping Zhang, Hong Mei, Mark W. Embrey, Sylvie M. Sur, Duane E. DeMong, Ravi P. Nargund, Alan Hruza, Heather E. Tiscia, Matthew J. Fell, Zhizhang Yin, Gautam Agnihotri, Honglu Zhang, Thomas J. Greshock, Jack D. Scott, Yinghui Lin, Zhi-Cai Shi, John A. Mccauley, Sarah W. Li, Ronald K. Chang, Mark T. Bilodeau, Michael W. Miller, Reshma Kuvelkar, Andrew Stamford, Marc Poirier, Hong Liu, Megan K. Macala, Kallol Basu, Li Xiao, Lynn A. Hyde, Jonathan T. Kern, Xing Dai, Christian Mirescu, Paul L. Walsh, Matthew E. Kennedy, John J. Renger, Zhiyong Hu, John Columbus, Robert E. Drolet, Eric M. Parker

المصدر: Journal of medicinal chemistry. 60(7)

مصطلحات موضوعية: 0301 basic medicine, Male, Indazoles, Leucine-rich repeat, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, Animals, Humans, c-Raf, Kinase activity, Enzyme Inhibitors, Rats, Wistar, biology, Cyclin-dependent kinase 4, Kinase, Chemistry, Cyclin-dependent kinase 2, Brain, Parkinson Disease, LRRK2, nervous system diseases, Rats, Molecular Docking Simulation, 030104 developmental biology, Protein kinase domain, Biochemistry, biology.protein, Molecular Medicine, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2ca3dd5156b7d725b7ec9d610b7b59
https://pubmed.ncbi.nlm.nih.gov/28245354

المؤلفون: John A. McCauley, Ronald K. Chang, Thomas J. Greshock, Ming-Tain Lai, John M. Sanders, Hemaka A. Rajapakse, Hua Su, Robert E. Drolet, Rosa I. Sanchez, Sylvie M. Sur, John J. Renger, Jonathan T. Kern, Heather E. Tiscia, Rada Vanessa L, Mark T. Bilodeau, Boyoung Kim

المصدر: Bioorganicmedicinal chemistry letters. 26(11)

مصطلحات موضوعية: 0301 basic medicine, Parkinson's disease, Clinical Biochemistry, Pharmaceutical Science, Administration, Oral, Biological Availability, Thiophenes, Leucine-rich repeat, Pharmacology, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, 0302 clinical medicine, Drug Discovery, medicine, Structure–activity relationship, Humans, Molecular Biology, Protein Kinase Inhibitors, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Kinase, Organic Chemistry, medicine.disease, LRRK2, Small molecule, nervous system diseases, Molecular Docking Simulation, 030104 developmental biology, Lactam, Molecular Medicine, Sample collection, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abff9d5807428b264eed0b0d1d39c6bc
https://pubmed.ncbi.nlm.nih.gov/27106707