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المؤلفون: Yan SB; Lilly Research Laboratories, Eli Lilly and Company, DC0522, 307 E McCarty Street, Indianapolis, IN 46285, USA. s.betty_yan@lilly.com, Peek VL, Ajamie R, Buchanan SG, Graff JR, Heidler SA, Hui YH, Huss KL, Konicek BW, Manro JR, Shih C, Stewart JA, Stewart TR, Stout SL, Uhlik MT, Um SL, Wang Y, Wu W, Yan L, Yang WJ, Zhong B, Walgren RA

المصدر: Investigational new drugs [Invest New Drugs] 2013 Aug; Vol. 31 (4), pp. 833-44. Date of Electronic Publication: 2012 Dec 29.

نوع المنشور: Clinical Trial, Phase I; Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 8309330 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-0646 (Electronic) Linking ISSN: 01676997 NLM ISO Abbreviation: Invest New Drugs Subsets: MEDLINE

مواضيع طبية MeSH: Indazoles/*pharmacology , Niacinamide/*analogs & derivatives , Protein Kinase Inhibitors/*pharmacology , Proto-Oncogene Proteins c-met/*antagonists & inhibitors , Receptor Protein-Tyrosine Kinases/*antagonists & inhibitors , Tetrazoles/*pharmacology, Administration, Oral ; Animals ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Biological Availability ; Blood Vessels/drug effects ; Blood Vessels/pathology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Humans ; Indazoles/administration & dosage ; Indazoles/chemistry ; Mice ; Mutation/genetics ; Niacinamide/administration & dosage ; Niacinamide/chemistry ; Niacinamide/pharmacology ; Protein Kinase Inhibitors/administration & dosage ; Protein Kinase Inhibitors/chemistry ; Proto-Oncogene Proteins c-met/metabolism ; Receptor Protein-Tyrosine Kinases/metabolism ; Tetrazoles/administration & dosage ; Tetrazoles/chemistry ; Xenograft Model Antitumor Assays

المؤلفون: Lee JA; Department of Quantitative and Structural Biology, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA. jonathan_a_lee@lilly.com, Chu S, Willard FS, Cox KL, Sells Galvin RJ, Peery RB, Oliver SE, Oler J, Meredith TD, Heidler SA, Gough WH, Husain S, Palkowitz AD, Moxham CM

المصدر: Journal of biomolecular screening [J Biomol Screen] 2011 Jul; Vol. 16 (6), pp. 588-602. Date of Electronic Publication: 2011 Apr 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Sage Publications Country of Publication: United States NLM ID: 9612112 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-454X (Electronic) Linking ISSN: 10870571 NLM ISO Abbreviation: J Biomol Screen Subsets: MEDLINE

مواضيع طبية MeSH: Drug Discovery* , Phenotype*, Animals ; Apolipoproteins E/metabolism ; Cell Cycle/drug effects ; Cell Differentiation/drug effects ; Cell Line ; Drug Evaluation, Preclinical ; HeLa Cells ; Humans ; Insulin/metabolism ; Insulin Secretion ; Mice ; Neovascularization, Physiologic/drug effects ; Nocodazole/pharmacology ; Osteoblasts/cytology ; Osteoblasts/metabolism ; Protein Kinase Inhibitors/pharmacology ; Rats ; Reproducibility of Results ; Signal Transduction/drug effects ; Tubulin Modulators/pharmacology ; Wnt Proteins/metabolism

المؤلفون: Becker MA; University of Chicago, IL., Heidler SA, Nosal JM, Switzer RL, LeBeau MM, Shapiro LJ, Palella TD, Roessler BJ

المصدر: Advances in experimental medicine and biology [Adv Exp Med Biol] 1991; Vol. 309B, pp. 129-32.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 0121103 Publication Model: Print Cited Medium: Print ISSN: 0065-2598 (Print) Linking ISSN: 00652598 NLM ISO Abbreviation: Adv Exp Med Biol Subsets: MEDLINE

مواضيع طبية MeSH: Ribose-Phosphate Pyrophosphokinase/*genetics, Chromosome Mapping ; DNA/genetics ; Genetic Linkage ; Humans ; Kinetics ; RNA/genetics ; Ribose-Phosphate Pyrophosphokinase/metabolism ; X Chromosome

المؤلفون: Becker MA; Department of Medicine, University of Chicago, Illinois 60637., Heidler SA, Bell GI, Seino S, Le Beau MM, Westbrook CA, Neuman W, Shapiro LJ, Mohandas TK, Roessler BJ, et. al.

المصدر: Genomics [Genomics] 1990 Nov; Vol. 8 (3), pp. 555-61.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 8800135 Publication Model: Print Cited Medium: Print ISSN: 0888-7543 (Print) Linking ISSN: 08887543 NLM ISO Abbreviation: Genomics Subsets: MEDLINE

مواضيع طبية MeSH: Ribose-Phosphate Pyrophosphokinase/*genetics, Animals ; Blotting, Southern ; Cell Line ; Chromosome Mapping ; Cricetinae ; Cricetulus ; DNA/genetics ; Genes ; Humans ; Hybrid Cells ; Mice ; Nucleic Acid Hybridization ; X Chromosome