المؤلفون: Kundert, K, Lucas, JE, Watters, KE, Fellmann, C, Ng, AH, Heineike, BM, Fitzsimmons, CM, Oakes, BL, Qu, J, Prasad, N, Rosenberg, OS, Savage, DF, El-Samad, H, Doudna, JA, Kortemme, T

المصدر: Nature communications. 10(1)

مصطلحات موضوعية: DNA, RNA, Guide, Ligands, Aptamers, Nucleotide, CRISPR-Cas Systems, Gene Editing, CRISPR-Associated Protein 9, Biochemistry and Cell Biology, Physical Sciences, Biological Sciences, Biotechnology, Genetics, Generic health relevance, RNA, Guide, Kinetoplastida

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3t52t2n5

المؤلفون: Correia-Melo C; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, UK; Department of Biochemistry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany. Electronic address: claramelo85@gmail.com., Kamrad S; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK., Tengölics R; Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, Eötvös Loránd Research Network, Szeged 6726, Hungary; HCEMM-BRC Metabolic Systems Biology Lab, Szeged 6726, Hungary., Messner CB; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Precision Proteomics Center, Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, 7265 Davos, Switzerland., Trebulle P; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK., Townsend S; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Department of Biochemistry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany., Jayasree Varma S; Department of Biochemistry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany., Freiwald A; Department of Biochemistry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany; Core Facility - High Throughput Mass Spectrometry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany., Heineike BM; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK; Quantitative Gene Expression Research Group, MRC London Institute of Medical Sciences (LMS), London W12 0HS, UK; Quantitative Gene Expression Research Group, Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London SW2 2AZ, UK., Campbell K; Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, UK., Herrera-Dominguez L; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK., Kaur Aulakh S; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK., Szyrwiel L; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Department of Biochemistry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany., Yu JSL; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK., Zelezniak A; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden; Randall Centre for Cell & Molecular Biophysics, King's College London, New Hunt's House, Guy's Campus, London SE1 1UL, UK; Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius 10257, Lithuania., Demichev V; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, UK; Department of Biochemistry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany., Mülleder M; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, UK; Core Facility - High Throughput Mass Spectrometry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany., Papp B; Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, Eötvös Loránd Research Network, Szeged 6726, Hungary; HCEMM-BRC Metabolic Systems Biology Lab, Szeged 6726, Hungary., Alam MT; Department of Biology, College of Science, United Arab Emirates University, P.O.Box 15551, Al-Ain, United Arab Emirates., Ralser M; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, UK; Department of Biochemistry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany; The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK. Electronic address: markus.ralser@charite.de.

المصدر: Cell [Cell] 2023 Jan 05; Vol. 186 (1), pp. 63-79.e21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Longevity* , Saccharomyces cerevisiae*/metabolism, Methionine/metabolism ; Signal Transduction

المؤلفون: Yu JSL; Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London, United Kingdom., Heineike BM; Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London, United Kingdom., Hartl J; Department of Biochemistry, Charité Universitätsmedizin, Berlin, Germany., Aulakh SK; Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London, United Kingdom., Correia-Melo C; Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London, United Kingdom., Lehmann A; Department of Biochemistry, Charité Universitätsmedizin, Berlin, Germany., Lemke O; Department of Biochemistry, Charité Universitätsmedizin, Berlin, Germany., Agostini F; Department of Biochemistry, Charité Universitätsmedizin, Berlin, Germany., Lee CT; Department of Biochemistry, Charité Universitätsmedizin, Berlin, Germany., Demichev V; Department of Biochemistry, Charité Universitätsmedizin, Berlin, Germany., Messner CB; Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London, United Kingdom., Mülleder M; Core Facility-High Throughput Mass Spectrometry, Charité Universitätsmedizin, Berlin, Germany., Ralser M; Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London, United Kingdom.; Department of Biochemistry, Charité Universitätsmedizin, Berlin, Germany.

المصدر: PLoS biology [PLoS Biol] 2022 Dec 01; Vol. 20 (12), pp. e3001912. Date of Electronic Publication: 2022 Dec 01 (Print Publication: 2022).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE

مواضيع طبية MeSH: Cysteine Synthase*/genetics , Cysteine Synthase*/metabolism , Methionine*/metabolism , Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae*/metabolism, Cysteine/metabolism ; Proteomics ; Racemethionine ; Sulfur/metabolism

المؤلفون: Vermeersch L; VIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.; CMPG Laboratory of Genetics and Genomics, Department M2S, KU Leuven, Leuven, Belgium., Jariani A; VIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.; CMPG Laboratory of Genetics and Genomics, Department M2S, KU Leuven, Leuven, Belgium., Helsen J; VIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium.; CMPG Laboratory of Genetics and Genomics, Department M2S, KU Leuven, Leuven, Belgium.; CMPG Laboratory of Predictive Genetics and Multicellular Systems, Department M2S, KU Leuven, Leuven, Belgium., Heineike BM; Molecular Biology of Metabolism Laboratory, Francis Crick Institute, London, UK.; Quantitative Gene Expression Research Group, MRC London Institute of Medical Sciences (LMS), London, UK.; Quantitative Gene Expression Research Group, Faculty of Medicine, Imperial College London, Institute of Clinical Sciences (ICS), London, UK., Verstrepen KJ; VIB Laboratory for Systems Biology, VIB-KU Leuven Center for Microbiology, Leuven, Belgium. kevin.verstrepen@kuleuven.be.; CMPG Laboratory of Genetics and Genomics, Department M2S, KU Leuven, Leuven, Belgium. kevin.verstrepen@kuleuven.be.

المصدر: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2022; Vol. 2477, pp. 3-20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Saccharomyces cerevisiae*/genetics , Single-Cell Analysis*/methods, Animals ; Chromium ; Gene Expression Profiling/methods ; Genomics ; Mammals/genetics ; RNA/genetics ; RNA-Seq ; Sequence Analysis, RNA/methods

المؤلفون: Heineike BM; Bioinformatics Graduate Program, University of California, San Francisco, San Francisco, CA, United States., El-Samad H; Department of Biochemistry and Biophysics, California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA, United States.; Chan Zuckerberg Biohub, San Francisco, CA, United States.

المصدر: Frontiers in fungal biology [Front Fungal Biol] 2021 Apr 27; Vol. 2, pp. 642336. Date of Electronic Publication: 2021 Apr 27 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 9918266300506676 Publication Model: eCollection Cited Medium: Internet ISSN: 2673-6128 (Electronic) Linking ISSN: 26736128 NLM ISO Abbreviation: Front Fungal Biol Subsets: PubMed not MEDLINE

المؤلفون: Liu L; Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158, USA. adam@abatelab.org., Dalal CK, Heineike BM, Abate AR

المصدر: Lab on a chip [Lab Chip] 2019 May 14; Vol. 19 (10), pp. 1838-1849.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101128948 Publication Model: Print Cited Medium: Internet ISSN: 1473-0189 (Electronic) Linking ISSN: 14730189 NLM ISO Abbreviation: Lab Chip Subsets: MEDLINE

مواضيع طبية MeSH: High-Throughput Nucleotide Sequencing*, Saccharomyces cerevisiae/*genetics, Gels/chemistry ; Gene Expression Profiling ; Genetic Engineering ; Particle Size ; Surface Properties