المؤلفون: David H. Spencer, Helton Nm, Jacqueline E. Payton, Heath Se, John F. DiPersio, Robert S. Fulton, Christopher A. Miller, Wilson Er, Peter Westervelt, John S. Welch, Daniel C. Link, Timothy J. Ley, Matthew J. Walter

مصطلحات موضوعية: Regulation of gene expression, ETV6, Mutant, DNA methylation, Bisulfite sequencing, Methylation, Biology, Enhancer, Gene, Molecular biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e521a60af8e90fff25861dd2b77e5269
https://doi.org/10.1101/2021.03.03.433799

المؤلفون: Katerndahl CDS; Division of Oncology, Department of Internal Medicine, Section of Stem Cell Biology, Washington University School of Medicine, St. Louis, MO 63110., Rogers ORS; Division of Oncology, Department of Internal Medicine, Section of Stem Cell Biology, Washington University School of Medicine, St. Louis, MO 63110., Day RB; Division of Oncology, Department of Internal Medicine, Section of Stem Cell Biology, Washington University School of Medicine, St. Louis, MO 63110., Xu Z; Division of Oncology, Department of Internal Medicine, Section of Stem Cell Biology, Washington University School of Medicine, St. Louis, MO 63110., Helton NM; Division of Oncology, Department of Internal Medicine, Section of Stem Cell Biology, Washington University School of Medicine, St. Louis, MO 63110., Ramakrishnan SM; Division of Oncology, Department of Internal Medicine, Section of Stem Cell Biology, Washington University School of Medicine, St. Louis, MO 63110., Miller CA; Division of Oncology, Department of Internal Medicine, Section of Stem Cell Biology, Washington University School of Medicine, St. Louis, MO 63110., Ley TJ; Division of Oncology, Department of Internal Medicine, Section of Stem Cell Biology, Washington University School of Medicine, St. Louis, MO 63110.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Apr 30; Vol. 121 (18), pp. e2317690121. Date of Electronic Publication: 2024 Apr 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: GATA2 Transcription Factor*/metabolism , GATA2 Transcription Factor*/genetics , Hematopoietic Stem Cells*/metabolism , Oncogene Proteins, Fusion*/metabolism , Oncogene Proteins, Fusion*/genetics, Animals ; Humans ; Mice ; Binding Sites ; Cell Self Renewal ; Chromatin/metabolism ; DNA/metabolism ; Leukemia, Promyelocytic, Acute/metabolism ; Leukemia, Promyelocytic, Acute/genetics ; Leukemia, Promyelocytic, Acute/pathology ; Promyelocytic Leukemia Protein/metabolism ; Promyelocytic Leukemia Protein/genetics ; Protein Binding ; Retinoic Acid Receptor alpha/metabolism ; Retinoic Acid Receptor alpha/genetics

المؤلفون: Li Y; Section of Stem Cell Biology, Division of Oncology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA., Abel HJ; Section of Stem Cell Biology, Division of Oncology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA., Cai M; Section of Stem Cell Biology, Division of Oncology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA., LaValle TA; Section of Stem Cell Biology, Division of Oncology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA., Yin T; Section of Stem Cell Biology, Division of Oncology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA., Helton NM; Section of Stem Cell Biology, Division of Oncology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA., Smith AM; Section of Stem Cell Biology, Division of Oncology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA., Miller CA; Section of Stem Cell Biology, Division of Oncology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA., Ley TJ; Section of Stem Cell Biology, Division of Oncology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA.

المصدر: Science advances [Sci Adv] 2024 Feb 02; Vol. 10 (5), pp. eadk8598. Date of Electronic Publication: 2024 Jan 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: DNA (Cytosine-5-)-Methyltransferases*/genetics , Leukemia, Myeloid, Acute*/genetics, Humans ; Mice ; Animals ; DNA Methyltransferase 3A ; DNA ; Mutation ; DNA Methylation

المؤلفون: Abel HJ; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Oetjen KA; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Miller CA; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Ramakrishnan SM; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Day RB; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Helton NM; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Fronick CC; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO., Fulton RS; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO., Heath SE; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Tarnawsky SP; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Nonavinkere Srivatsan S; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Duncavage EJ; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO., Schroeder MC; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO., Payton JE; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO., Spencer DH; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO.; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO., Walter MJ; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Westervelt P; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., DiPersio JF; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Ley TJ; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Link DC; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.

المصدر: Blood advances [Blood Adv] 2023 Aug 22; Vol. 7 (16), pp. 4586-4598.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

مواضيع طبية MeSH: Chromothripsis* , Leukemia, Myeloid, Acute*/genetics , Leukemia, Myeloid, Acute*/pathology , Myeloproliferative Disorders*/genetics , Myelodysplastic Syndromes*/genetics , Myelodysplastic Syndromes*/pathology, Humans ; Mutation ; Chromosome Aberrations ; Genomics ; Tumor Suppressor Protein p53/genetics

المؤلفون: Li S; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO.; Hematology Oncology Center, Beijing Children's Hospital, National Center for Children's Health, Capital Medial University, Beijing, China.; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Yao JC; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO., Oetjen KA; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO., Krambs JR; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO., Xia J; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO., Zhang J; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO., Schmidt AP; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO., Helton NM; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO., Fulton RS; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO., Heath SE; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO., Turnbull IR; Department of Surgery, Washington University School of Medicine, St. Louis, MO., Mbalaviele G; Division of Bone and Mineral Disease, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO., Ley TJ; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO., Walter MJ; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO., Link DC; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO.

المصدر: Blood [Blood] 2022 Oct 06; Vol. 140 (14), pp. 1607-1620.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Bone Marrow Cells*/cytology , Dendritic Cells*/cytology , Hematopoietic Stem Cells*/cytology , Interleukin-1beta*/metabolism , Myelodysplastic Syndromes*/metabolism, Animals ; Bone Marrow/metabolism ; Cytokines/metabolism ; Humans ; Mice ; Myeloid Differentiation Factor 88/metabolism ; RNA/metabolism ; Toll-Like Receptor 1/metabolism ; Toll-Like Receptor 2/agonists ; Toll-Like Receptor 2/metabolism

المؤلفون: Kramer MH; Division of Oncology, Department of Internal Medicine., Zhang Q; Division of Endocrinology, Metabolism, and Lipid Research, and., Sprung R; Division of Endocrinology, Metabolism, and Lipid Research, and., Day RB; Division of Oncology, Department of Internal Medicine., Erdmann-Gilmore P; Division of Endocrinology, Metabolism, and Lipid Research, and., Li Y; Division of Oncology, Department of Internal Medicine., Xu Z; Division of Oncology, Department of Internal Medicine., Helton NM; Division of Oncology, Department of Internal Medicine., George DR; Division of Oncology, Department of Internal Medicine., Mi Y; Division of Endocrinology, Metabolism, and Lipid Research, and., Westervelt P; Division of Oncology, Department of Internal Medicine., Payton JE; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO., Ramakrishnan SM; Division of Oncology, Department of Internal Medicine., Miller CA; Division of Oncology, Department of Internal Medicine., Link DC; Division of Oncology, Department of Internal Medicine., DiPersio JF; Division of Oncology, Department of Internal Medicine., Walter MJ; Division of Oncology, Department of Internal Medicine., Townsend RR; Division of Endocrinology, Metabolism, and Lipid Research, and., Ley TJ; Division of Oncology, Department of Internal Medicine.

المصدر: Blood [Blood] 2022 Sep 29; Vol. 140 (13), pp. 1533-1548.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid, Acute*/pathology , Nuclear Proteins*/genetics, Histone Demethylases/metabolism ; Humans ; Jumonji Domain-Containing Histone Demethylases ; Karyopherins/genetics ; Ketoglutaric Acids ; Membrane Proteins/genetics ; Mutation ; Nucleophosmin ; Proteome/metabolism ; Proteomics ; RNA, Messenger ; Serine/genetics ; fms-Like Tyrosine Kinase 3/genetics ; src-Family Kinases/metabolism

المؤلفون: Wilson ER; Department of Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University, St. Louis, MO, USA., Helton NM; Department of Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University, St. Louis, MO, USA., Heath SE; Department of Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University, St. Louis, MO, USA., Fulton RS; McDonnell Genome Institute, Washington University, St. Louis, MO, USA., Payton JE; Department of Pathology and Immunology, Washington University, St. Louis, MO, USA., Welch JS; Department of Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University, St. Louis, MO, USA., Walter MJ; Department of Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University, St. Louis, MO, USA., Westervelt P; Department of Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University, St. Louis, MO, USA., DiPersio JF; Department of Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University, St. Louis, MO, USA., Link DC; Department of Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University, St. Louis, MO, USA., Miller CA; Department of Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University, St. Louis, MO, USA.; McDonnell Genome Institute, Washington University, St. Louis, MO, USA., Ley TJ; Department of Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University, St. Louis, MO, USA., Spencer DH; Department of Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University, St. Louis, MO, USA. dspencer@wustl.edu.; Department of Pathology and Immunology, Washington University, St. Louis, MO, USA. dspencer@wustl.edu.; McDonnell Genome Institute, Washington University, St. Louis, MO, USA. dspencer@wustl.edu.

المصدر: Leukemia [Leukemia] 2022 Apr; Vol. 36 (4), pp. 935-945. Date of Electronic Publication: 2021 Dec 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

مواضيع طبية MeSH: DNA Methylation* , Leukemia, Myeloid, Acute*/genetics , Leukemia, Myeloid, Acute*/pathology, Humans ; Isocitrate Dehydrogenase/genetics ; Mutation ; Regulatory Sequences, Nucleic Acid

المؤلفون: Ferraro F; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Siteman Cancer Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Miller CA; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Siteman Cancer Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Christensen KA; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Helton NM; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., O'Laughlin M; McDonnell Genome Institute, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Fronick CC; McDonnell Genome Institute, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Fulton RS; McDonnell Genome Institute, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Kohlschmidt J; The Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH 43210.; Alliance Statistics and Data Center, The Ohio State University Comprehensive Cancer Center, Columbus, OH 43210., Eisfeld AK; The Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH 43210.; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH 43210., Bloomfield CD; The Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH 43210.; Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH 43210., Ramakrishnan SM; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Day RB; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Wartman LD; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Siteman Cancer Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Uy GL; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Siteman Cancer Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Welch JS; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Siteman Cancer Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Christopher MJ; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Siteman Cancer Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Heath SE; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Baty JD; Division of Biostatistics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Schuelke MJ; Division of Biostatistics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Payton JE; Department of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Spencer DH; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Siteman Cancer Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Rettig MP; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Siteman Cancer Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Link DC; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Siteman Cancer Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Walter MJ; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Siteman Cancer Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Westervelt P; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Siteman Cancer Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., DiPersio JF; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.; Siteman Cancer Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110., Ley TJ; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110; timley@wustl.edu.; Siteman Cancer Center, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Dec 07; Vol. 118 (49).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Immune Tolerance/*genetics , Leukemia, Myeloid, Acute/*genetics , Leukemia, Myeloid, Acute/*immunology, Adult ; CD4-Positive T-Lymphocytes/immunology ; Female ; Humans ; Immune Tolerance/immunology ; Karyotype ; Leukemia, Myeloid, Acute/therapy ; Male ; Middle Aged ; Prognosis ; Recurrence ; Remission Induction ; Risk Factors ; Sequence Analysis, RNA/methods ; Th1 Cells/immunology ; Transcriptome/genetics ; Treatment Outcome

المؤلفون: Tian L; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, United States of America., Chavez M; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, United States of America., Chang GS; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, United States of America., Helton NM; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, United States of America., Katerndahl CDS; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, United States of America., Miller CA; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, United States of America.; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, United States of America., Wartman LD; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, United States of America.

المصدر: PloS one [PLoS One] 2021 Nov 15; Vol. 16 (11), pp. e0255706. Date of Electronic Publication: 2021 Nov 15 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Histone Demethylases/*genetics , Myelodysplastic Syndromes/*genetics, Age Factors ; Animals ; Chromatin ; Female ; Hematopoietic Stem Cells/metabolism ; Histone Demethylases/metabolism ; Male ; Mice ; Mice, Knockout ; Myelodysplastic Syndromes/metabolism ; Phenotype ; Sex Factors

المؤلفون: Katerndahl CDS; Section of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO., Rogers ORS; Section of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO., Day RB; Section of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO., Cai MA; Section of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO., Rooney TP; Section of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO., Helton NM; Section of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO., Hoock M; Section of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO., Ramakrishnan SM; Section of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO., Nonavinkere Srivatsan S; Section of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO., Wartman LD; Section of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO., Miller CA; Section of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO., Ley TJ; Section of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO.

المصدر: Blood [Blood] 2021 Sep 30; Vol. 138 (13), pp. 1148-1161.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: GATA2 Transcription Factor/*genetics , Leukemia, Promyelocytic, Acute/*genetics, Animals ; CRISPR-Cas Systems ; Cell Line, Tumor ; Disease Progression ; GATA2 Transcription Factor/metabolism ; Gene Expression Regulation, Leukemic ; Genes, Tumor Suppressor ; Humans ; Leukemia, Promyelocytic, Acute/metabolism ; Leukemia, Promyelocytic, Acute/pathology ; Mice ; Mutation