المؤلفون: Jakobsen NA; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK; Oxford Centre for Haematology, NIHR Oxford Biomedical Research Centre, Oxford, UK., Turkalj S; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK; Oxford Centre for Haematology, NIHR Oxford Biomedical Research Centre, Oxford, UK., Zeng AGX; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Stoilova B; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Metzner M; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Rahmig S; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Nagree MS; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Shah S; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Moore R; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Usukhbayar B; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Angulo Salazar M; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Gafencu GA; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Kennedy A; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK; Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Newman S; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, UK; Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Kendrick BJL; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, UK; Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Taylor AH; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, UK; Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Afinowi-Luitz R; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, UK; Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Gundle R; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, UK; Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Watkins B; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, UK., Wheway K; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, UK., Beazley D; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, UK., Murison A; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Aguilar-Navarro AG; Unidad de Investigación Médica en Enfermedades Oncológicas, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Flores-Figueroa E; Unidad de Investigación Médica en Enfermedades Oncológicas, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Dakin SG; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, UK., Carr AJ; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, UK; Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Nerlov C; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Dick JE; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Xie SZ; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Vyas P; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK; Oxford Centre for Haematology, NIHR Oxford Biomedical Research Centre, Oxford, UK; Department of Haematology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Electronic address: paresh.vyas@imm.ox.ac.uk.

المصدر: Cell stem cell [Cell Stem Cell] 2024 Aug 01; Vol. 31 (8), pp. 1127-1144.e17. Date of Electronic Publication: 2024 Jun 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101311472 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-9777 (Electronic) Linking ISSN: 18759777 NLM ISO Abbreviation: Cell Stem Cell Subsets: MEDLINE

مواضيع طبية MeSH: Inflammation*/genetics , Inflammation*/pathology , Aging*/genetics , Clonal Hematopoiesis*/genetics , Mutation*/genetics , DNA Methyltransferase 3A* , Dioxygenases* , Hematopoietic Stem Cells*/metabolism , DNA (Cytosine-5-)-Methyltransferases*/genetics , DNA (Cytosine-5-)-Methyltransferases*/metabolism, Humans ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism ; Hematopoiesis/genetics

المؤلفون: Wang H; Department of Basic and Translational Sciences, Laboratory of Innate Immunity and Inflammation, Penn Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Divaris K; Division of Pediatric and Public Health, Adams School of Dentistry, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599, USA; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599, USA., Pan B; Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA., Li X; Department of Basic and Translational Sciences, Laboratory of Innate Immunity and Inflammation, Penn Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Shanghai Jiao Tong University, School of Life Sciences and Biotechnology, Sheng Yushou Center of Cell Biology and Immunology, Shanghai 200240, China., Lim JH; Department of Basic and Translational Sciences, Laboratory of Innate Immunity and Inflammation, Penn Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Saha G; Department of Basic and Translational Sciences, Laboratory of Innate Immunity and Inflammation, Penn Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Barovic M; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital, Technische Universität Dresden, 01307 Dresden, Germany., Giannakou D; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital, Technische Universität Dresden, 01307 Dresden, Germany., Korostoff JM; Department of Periodontics, Laboratory of Innate Immunity and Inflammation, Penn Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Bing Y; Human Genetics Center, Department of Epidemiology, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Sen S; Department of Neurology, University of South Carolina, Columbia, SC 29209, USA; Center for the Study of Aphasia Recovery, University of South Carolina, Columbia, SC 29209, USA., Moss K; Department of Biostatistics and Health Data Sciences, School of Medicine, Indiana University, Indianapolis, IN 46202, USA; Division of Oral and Craniofacial Health Sciences, Adams School of Dentistry, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599, USA., Wu D; Division of Oral and Craniofacial Health Sciences, Adams School of Dentistry, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599, USA; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599, USA., Beck JD; Division of Comprehensive Oral Health-Periodontology, Adams School of Dentistry, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599, USA., Ballantyne CM; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA., Natarajan P; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02141, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA., North KE; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599, USA., Netea MG; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 XZ Nijmegen, the Netherlands; Department of Immunology and Metabolism, LIMES, University of Bonn, 53115 Bonn, Germany., Chavakis T; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital, Technische Universität Dresden, 01307 Dresden, Germany., Hajishengallis G; Department of Basic and Translational Sciences, Laboratory of Innate Immunity and Inflammation, Penn Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: geoh@upenn.edu.

المصدر: Cell [Cell] 2024 Jul 11; Vol. 187 (14), pp. 3690-3711.e19. Date of Electronic Publication: 2024 Jun 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: DNA Methyltransferase 3A* , DNA (Cytosine-5-)-Methyltransferases*/metabolism , DNA (Cytosine-5-)-Methyltransferases*/genetics , Clonal Hematopoiesis*/genetics , Periodontitis*/genetics , Periodontitis*/pathology, Animals ; Mice ; Humans ; Mutation ; Male ; Female ; Inflammation/genetics ; Inflammation/pathology ; Osteoclasts/metabolism ; Mice, Inbred C57BL ; Adult ; Interleukin-17/metabolism ; Interleukin-17/genetics ; T-Lymphocytes, Regulatory/immunology ; T-Lymphocytes, Regulatory/metabolism ; Hematopoiesis/genetics ; Osteogenesis/genetics ; Hematopoietic Stem Cells/metabolism ; Bone Resorption/genetics ; Bone Resorption/pathology ; Middle Aged

المؤلفون: Mack T; Vanderbilt Genetics Institute, Vanderbilt University School of Medicine, Nashville, Tennessee., Vlasschaert C; Department of Medicine, Queen's University, Kingston, Ontario, Canada., von Beck K; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Silver AJ; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; Program in Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee., Heimlich JB; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Poisner H; Vanderbilt Genetics Institute, Vanderbilt University School of Medicine, Nashville, Tennessee., Condon HR; Vanderbilt Genetics Institute, Vanderbilt University School of Medicine, Nashville, Tennessee., Ulloa J; Vanderbilt Genetics Institute, Vanderbilt University School of Medicine, Nashville, Tennessee., Sochacki AL; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Spaulding TP; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Kishtagari A; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Bejan CA; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee., Xu Y; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee., Savona MR; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; Program in Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee; Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee; Center for Immunobiology, Vanderbilt University Medical Center, Nashville, Tennessee., Jones A; Vanderbilt Genetics Institute, Vanderbilt University School of Medicine, Nashville, Tennessee., Bick AG; Vanderbilt Genetics Institute, Vanderbilt University School of Medicine, Nashville, Tennessee; Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address: alexander.bick@vumc.org.

المصدر: The Journal of molecular diagnostics : JMD [J Mol Diagn] 2024 Jul; Vol. 26 (7), pp. 563-573. Date of Electronic Publication: 2024 Apr 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 100893612 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-7811 (Electronic) Linking ISSN: 15251578 NLM ISO Abbreviation: J Mol Diagn Subsets: MEDLINE

مواضيع طبية MeSH: Clonal Hematopoiesis*/genetics , Mutation*, Humans ; Male ; Female ; Aged ; Middle Aged ; Adult ; High-Throughput Nucleotide Sequencing/methods ; High-Throughput Nucleotide Sequencing/economics ; Cost-Benefit Analysis ; Hematopoietic Stem Cells/metabolism ; Hematopoietic Stem Cells/cytology ; Clonal Evolution/genetics ; Aged, 80 and over ; Hematopoiesis/genetics

المؤلفون: Pourebrahim R; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Montoya RH; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Akiyama H; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Ostermann L; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Khazaei S; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Muftuoglu M; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Baran N; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Zhao R; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Lesluyes T; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK., Liu B; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Khoury JD; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA., Gagea M; Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Van Loo P; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Andreeff M; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: mandreef@mdanderson.org.

المصدر: Cell reports. Medicine [Cell Rep Med] 2024 May 21; Vol. 5 (5), pp. 101558. Date of Electronic Publication: 2024 May 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE

مواضيع طبية MeSH: Tumor Suppressor Protein p53*/genetics , Tumor Suppressor Protein p53*/metabolism , Leukemia, Myeloid, Acute*/genetics , Leukemia, Myeloid, Acute*/pathology , Clonal Hematopoiesis*/genetics , Mutation*/genetics , Proto-Oncogene Proteins c-mdm2*/genetics , Proto-Oncogene Proteins c-mdm2*/metabolism , Hematopoietic Stem Cells*/metabolism , Hematopoietic Stem Cells*/pathology, Animals ; Mice ; Mice, Inbred C57BL ; Haploinsufficiency/genetics ; Disease Models, Animal ; Hematopoiesis/genetics

المؤلفون: Cochran JD; Hematovascular Biology Center, Division of Cardiovascular Medicine and Robert M. Berne Cardiovascular Research Center (J.D.C., K.W.), University of Virginia School of Medicine, Charlottesville.; Medical Scientist Training Program (J.D.C.), University of Virginia School of Medicine, Charlottesville., Walsh K; Hematovascular Biology Center, Division of Cardiovascular Medicine and Robert M. Berne Cardiovascular Research Center (J.D.C., K.W.), University of Virginia School of Medicine, Charlottesville.

المصدر: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2024 Apr; Vol. 44 (4), pp. 768-771. Date of Electronic Publication: 2024 Mar 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler Thromb Vasc Biol Subsets: MEDLINE

مواضيع طبية MeSH: Clonal Hematopoiesis*/genetics , Cardiovascular Diseases*/epidemiology , Cardiovascular Diseases*/genetics, Humans ; Risk Factors ; Mutation ; Hematopoiesis/genetics

المصدر: Nature genetics [Nat Genet] 2024 Jun; Vol. 56 (6), pp. 1049-1050.

نوع المنشور: Letter; Journal Article

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: Mutation* , Clonal Hematopoiesis*/genetics , Aging*/genetics, Humans ; Hematopoiesis/genetics ; Male ; Aged

المؤلفون: Winter S; Department of Internal Medicine I, University Hospital Carl Gustav Carus, Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany., Götze KS; German Cancer Consortium (DKTK), CHOICE Consortium, Partner Sites Dresden/Munich/Frankfurt/Mainz, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Medicine III, Technical University of Munich (TUM), School of Medicine and Health, Munich, Germany.; German MDS Study Group (D-MDS), Leipzig, Germany., Hecker JS; German Cancer Consortium (DKTK), CHOICE Consortium, Partner Sites Dresden/Munich/Frankfurt/Mainz, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Medicine III, Technical University of Munich (TUM), School of Medicine and Health, Munich, Germany.; TranslaTUM, Center for Translational Cancer Research, Technical University of Munich (TUM), Munich, Germany., Metzeler KH; German Cancer Consortium (DKTK), CHOICE Consortium, Partner Sites Dresden/Munich/Frankfurt/Mainz, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Hematology, Cellular Therapy, Hemostaseology and Infectious Disease, University of Leipzig Medical Center, Leipzig, Germany., Guezguez B; German Cancer Consortium (DKTK), CHOICE Consortium, Partner Sites Dresden/Munich/Frankfurt/Mainz, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Hematology and Oncology, University Medical Center Mainz, Mainz, Germany., Woods K; German Cancer Consortium (DKTK), CHOICE Consortium, Partner Sites Dresden/Munich/Frankfurt/Mainz, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Hematology and Oncology, University Medical Center Mainz, Mainz, Germany., Medyouf H; German Cancer Consortium (DKTK), CHOICE Consortium, Partner Sites Dresden/Munich/Frankfurt/Mainz, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Frankfurt am Main, Germany., Schäffer A; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany., Schmitz M; German Cancer Consortium (DKTK), CHOICE Consortium, Partner Sites Dresden/Munich/Frankfurt/Mainz, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Immunology, Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany.; National Center for Tumor Diseases (NCT), Dresden, Germany: German Cancer Research Center (DKFZ), Heidelberg, Germany; Faculty of Medicine and University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Wehner R; German Cancer Consortium (DKTK), CHOICE Consortium, Partner Sites Dresden/Munich/Frankfurt/Mainz, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Immunology, Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany.; National Center for Tumor Diseases (NCT), Dresden, Germany: German Cancer Research Center (DKFZ), Heidelberg, Germany; Faculty of Medicine and University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Glauche I; Institute for Medical Informatics and Biometry, Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany., Roeder I; German Cancer Consortium (DKTK), CHOICE Consortium, Partner Sites Dresden/Munich/Frankfurt/Mainz, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), Dresden, Germany: German Cancer Research Center (DKFZ), Heidelberg, Germany; Faculty of Medicine and University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; Institute for Medical Informatics and Biometry, Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany., Rauner M; Division of Endocrinology, Diabetes and Bone Diseases, Department of Medicine III, and Center for Healthy Aging, University Medical Center, TU Dresden, Dresden, Germany., Hofbauer LC; German Cancer Consortium (DKTK), CHOICE Consortium, Partner Sites Dresden/Munich/Frankfurt/Mainz, and German Cancer Research Center (DKFZ), Heidelberg, Germany. Lorenz.Hofbauer@ukdd.de.; Division of Endocrinology, Diabetes and Bone Diseases, Department of Medicine III, and Center for Healthy Aging, University Medical Center, TU Dresden, Dresden, Germany. Lorenz.Hofbauer@ukdd.de., Platzbecker U; German Cancer Consortium (DKTK), CHOICE Consortium, Partner Sites Dresden/Munich/Frankfurt/Mainz, and German Cancer Research Center (DKFZ), Heidelberg, Germany. Uwe.Platzbecker@medizin.uni-leipzig.de.; German MDS Study Group (D-MDS), Leipzig, Germany. Uwe.Platzbecker@medizin.uni-leipzig.de.; Department of Hematology, Cellular Therapy, Hemostaseology and Infectious Disease, University of Leipzig Medical Center, Leipzig, Germany. Uwe.Platzbecker@medizin.uni-leipzig.de.

المصدر: Leukemia [Leukemia] 2024 May; Vol. 38 (5), pp. 936-946. Date of Electronic Publication: 2024 Mar 21.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

مواضيع طبية MeSH: Clonal Hematopoiesis*/genetics , Stem Cell Niche* , Aging*/genetics , Aging*/physiology, Humans ; Bone Marrow/metabolism ; Bone Marrow/pathology ; Hematopoietic Stem Cells/metabolism ; Hematopoietic Stem Cells/cytology ; Mutation ; Hematologic Neoplasms/genetics ; Hematologic Neoplasms/pathology ; Animals ; Hematopoiesis/genetics

المؤلفون: Austin R; Department of Pathology, NYU Grossman School of Medicine, New York, New York.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, New York., Aifantis I; Department of Pathology, NYU Grossman School of Medicine, New York, New York.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, New York.

المصدر: Blood cancer discovery [Blood Cancer Discov] 2024 May 01; Vol. 5 (3), pp. 139-141.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Comment

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101764786 Publication Model: Print Cited Medium: Internet ISSN: 2643-3249 (Electronic) Linking ISSN: 26433230 NLM ISO Abbreviation: Blood Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Clonal Evolution*/genetics , Clonal Hematopoiesis*/genetics , Mutation*, Humans ; Bone Marrow ; Hematopoiesis/genetics ; Hematopoietic Stem Cells/cytology

المؤلفون: Gudmundsson S; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Genomic Medicine, Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Carlston CM; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.; Center for Genomic Medicine, Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., O'Donnell-Luria A; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA. odonnell@broadinstitute.org.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. odonnell@broadinstitute.org.; Center for Genomic Medicine, Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA. odonnell@broadinstitute.org.

المصدر: Human genetics [Hum Genet] 2024 Apr; Vol. 143 (4), pp. 545-549. Date of Electronic Publication: 2023 Feb 04.

نوع المنشور: Journal Article; Review; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7613873 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1203 (Electronic) Linking ISSN: 03406717 NLM ISO Abbreviation: Hum Genet Subsets: MEDLINE

مواضيع طبية MeSH: Clonal Hematopoiesis*/genetics, Humans ; Genome, Human ; Databases, Genetic ; Genetic Variation ; Genetics, Population/methods ; Genetic Predisposition to Disease ; Hematopoiesis/genetics

المؤلفون: Bogdanov AN; Saint-Petersburg State University, 7-9 University embankment, St. Petersburg 199034, Russian Federation, e-mail: anbmapo2008@yandex.ru.; City Hospital № 40, 9 Borisov str., Sestroretsk, St. Petersburg 197701, Russian Federation., Voloshin SV; Russian Research Institute of Hematology and Transfusiology, 16 str. 2nd Sovetskaya , 16, St. Petersburg 191024, Russian Federation.; S.M.Kirov Military Medical Academy, 6 Akademik Lebedev str., St. Petersburg 194044, Russian Federation.; Leningrad Regional Clinical Hospital, 45 bldg. 1 lit. A Lunacharskogo ave., St. Petersburg 194291, Russian Federation., Kunevich EO; Russian Research Institute of Hematology and Transfusiology, 16 str. 2nd Sovetskaya , 16, St. Petersburg 191024, Russian Federation., Mikhaleva MA; Russian Research Institute of Hematology and Transfusiology, 16 str. 2nd Sovetskaya , 16, St. Petersburg 191024, Russian Federation.

المصدر: Advances in gerontology = Uspekhi gerontologii [Adv Gerontol] 2024; Vol. 37 (3), pp. 266-275.

نوع المنشور: Journal Article; Review; English Abstract

بيانات الدورية: Publisher: Ėskulap Country of Publication: Russia (Federation) NLM ID: 100971443 Publication Model: Print Cited Medium: Print ISSN: 1561-9125 (Print) Linking ISSN: 15619125 NLM ISO Abbreviation: Adv Gerontol Subsets: MEDLINE

مواضيع طبية MeSH: Aging*/physiology , Aging*/genetics , Epigenesis, Genetic* , Clonal Hematopoiesis*/genetics, Humans ; Mutation ; DNA Methylation ; Hematopoietic Stem Cells/metabolism ; DNA Methyltransferase 3A ; Hematologic Neoplasms/genetics ; Hematologic Neoplasms/diagnosis ; Dioxygenases ; Hematopoiesis/genetics ; Hematopoiesis/physiology ; DNA (Cytosine-5-)-Methyltransferases/genetics