المؤلفون: Ito R; Central Institute for Experimental Medicine and Life Science, Kawasaki, Kanagawa, 210-0821, Japan. rito@ciea.or.jp., Ohno Y; Central Institute for Experimental Medicine and Life Science, Kawasaki, Kanagawa, 210-0821, Japan., Mu Y; Central Institute for Experimental Medicine and Life Science, Kawasaki, Kanagawa, 210-0821, Japan.; Department of Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN, 55905, USA., Ka Y; Central Institute for Experimental Medicine and Life Science, Kawasaki, Kanagawa, 210-0821, Japan., Ito S; Central Institute for Experimental Medicine and Life Science, Kawasaki, Kanagawa, 210-0821, Japan., Emi-Sugie M; Central Institute for Experimental Medicine and Life Science, Kawasaki, Kanagawa, 210-0821, Japan., Mochizuki M; Central Institute for Experimental Medicine and Life Science, Kawasaki, Kanagawa, 210-0821, Japan., Kawai K; Central Institute for Experimental Medicine and Life Science, Kawasaki, Kanagawa, 210-0821, Japan., Goto M; Central Institute for Experimental Medicine and Life Science, Kawasaki, Kanagawa, 210-0821, Japan., Ogura T; Central Institute for Experimental Medicine and Life Science, Kawasaki, Kanagawa, 210-0821, Japan., Takahashi R; Central Institute for Experimental Medicine and Life Science, Kawasaki, Kanagawa, 210-0821, Japan., Niwa A; Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan., Nakahata T; Central Institute for Experimental Medicine and Life Science, Kawasaki, Kanagawa, 210-0821, Japan., Ito M; Central Institute for Experimental Medicine and Life Science, Kawasaki, Kanagawa, 210-0821, Japan.

المصدر: Stem cell research & therapy [Stem Cell Res Ther] 2024 Jun 21; Vol. 15 (1), pp. 182. Date of Electronic Publication: 2024 Jun 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE

مواضيع طبية MeSH: Proto-Oncogene Proteins c-kit*/metabolism , Proto-Oncogene Proteins c-kit*/genetics , Hematopoiesis* , Hematopoietic Stem Cells*/metabolism , Hematopoietic Stem Cells*/cytology , Hematopoietic Stem Cell Transplantation*/methods, Animals ; Humans ; Mice ; Mice, Transgenic ; Cell Lineage ; Antigens, CD34/metabolism ; Interleukin-3/metabolism ; Interleukin-3/genetics ; Mutation

المؤلفون: Hybel TE; Department of Hematology, Aarhus University Hospital, 8200 Aarhus N, Denmark.; Department of Clinical Medicine, Aarhus University, 8200 Aarhus N, Denmark., Jensen SH; Department of Hematology, Aarhus University Hospital, 8200 Aarhus N, Denmark.; Department of Clinical Medicine, Aarhus University, 8200 Aarhus N, Denmark., Rodrigues MA; Amnis Flow Cytometry, Cytek Biosciences, Seattle, WA 98119, USA., Hybel TE; Department of Hematology, Aarhus University Hospital, 8200 Aarhus N, Denmark., Pedersen MN; Department of Hematology, Aarhus University Hospital, 8200 Aarhus N, Denmark.; Department of Clinical Medicine, Aarhus University, 8200 Aarhus N, Denmark., Qvick SH; Department of Hematology, Aarhus University Hospital, 8200 Aarhus N, Denmark., Enemark MH; Department of Hematology, Aarhus University Hospital, 8200 Aarhus N, Denmark.; Department of Clinical Medicine, Aarhus University, 8200 Aarhus N, Denmark., Bill M; Department of Hematology, Aarhus University Hospital, 8200 Aarhus N, Denmark.; Department of Clinical Medicine, Aarhus University, 8200 Aarhus N, Denmark., Rosenberg CA; Department of Hematology, Aarhus University Hospital, 8200 Aarhus N, Denmark., Ludvigsen M; Department of Hematology, Aarhus University Hospital, 8200 Aarhus N, Denmark.; Department of Clinical Medicine, Aarhus University, 8200 Aarhus N, Denmark.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 12; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid, Acute*/pathology , Flow Cytometry*/methods , Neural Networks, Computer* , Hematopoietic Stem Cells*/pathology , Hematopoietic Stem Cells*/metabolism , Neoplastic Stem Cells*/pathology , Neoplastic Stem Cells*/metabolism, Humans ; Immunophenotyping/methods ; Female ; Male ; Image Processing, Computer-Assisted/methods ; Middle Aged

المؤلفون: Liu W; Department of Pathology, The University of Chicago, Chicago, IL 60637, USA; Committee on Cancer Biology, The University of Chicago, Chicago, IL 60637, USA., Kurkewich JL; Department of Pathology, The University of Chicago, Chicago, IL 60637, USA., Stoddart A; Department of Pathology, The University of Chicago, Chicago, IL 60637, USA., Khan S; Department of Pathology, The University of Chicago, Chicago, IL 60637, USA., Anandan D; Department of Pathology, The University of Chicago, Chicago, IL 60637, USA., Gaubil AN; Department of Pathology, The University of Chicago, Chicago, IL 60637, USA., Wolfgeher DJ; Department of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, IL 60637, USA., Jueng L; Department of Pathology, The University of Chicago, Chicago, IL 60637, USA., Kron SJ; The University of Chicago Medicine Comprehensive Cancer Center, The University of Chicago, Chicago, IL 60637, USA; Committee on Cancer Biology, The University of Chicago, Chicago, IL 60637, USA; Department of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, IL 60637, USA., McNerney ME; Department of Pathology, The University of Chicago, Chicago, IL 60637, USA; The University of Chicago Medicine Comprehensive Cancer Center, The University of Chicago, Chicago, IL 60637, USA; Committee on Cancer Biology, The University of Chicago, Chicago, IL 60637, USA; Department of Pediatrics, Section of Hematology/Oncology, The University of Chicago, Chicago, IL 60637, USA. Electronic address: megan.mcnerney@bsd.uchicago.edu.

المصدر: Cell reports [Cell Rep] 2024 May 28; Vol. 43 (5), pp. 114227. Date of Electronic Publication: 2024 May 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Homeodomain Proteins*/metabolism , Homeodomain Proteins*/genetics , Hematopoietic Stem Cells*/metabolism , Hematopoietic Stem Cells*/cytology , Chromatin*/metabolism , Repressor Proteins*/metabolism , Repressor Proteins*/genetics, Humans ; Transcription Factors/metabolism ; Transcription Factors/genetics ; Animals ; Mice ; Nuclear Proteins/metabolism ; Nuclear Proteins/genetics ; Cell Lineage ; Chromatin Assembly and Disassembly ; Cell Differentiation ; DNA-Binding Proteins/metabolism ; DNA-Binding Proteins/genetics ; Enhancer Elements, Genetic/genetics

المؤلفون: Pourebrahim R; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Montoya RH; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Akiyama H; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Ostermann L; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Khazaei S; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Muftuoglu M; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Baran N; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Zhao R; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Lesluyes T; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK., Liu B; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Khoury JD; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA., Gagea M; Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Van Loo P; Cancer Genomics Laboratory, The Francis Crick Institute, London, UK; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Andreeff M; Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: mandreef@mdanderson.org.

المصدر: Cell reports. Medicine [Cell Rep Med] 2024 May 21; Vol. 5 (5), pp. 101558. Date of Electronic Publication: 2024 May 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE

مواضيع طبية MeSH: Tumor Suppressor Protein p53*/genetics , Tumor Suppressor Protein p53*/metabolism , Leukemia, Myeloid, Acute*/genetics , Leukemia, Myeloid, Acute*/pathology , Clonal Hematopoiesis*/genetics , Mutation*/genetics , Proto-Oncogene Proteins c-mdm2*/genetics , Proto-Oncogene Proteins c-mdm2*/metabolism , Hematopoietic Stem Cells*/metabolism , Hematopoietic Stem Cells*/pathology, Animals ; Mice ; Mice, Inbred C57BL ; Haploinsufficiency/genetics ; Disease Models, Animal ; Hematopoiesis/genetics

المؤلفون: Monticelli S; IGBMC, Institut de Génétique et de Biologie Moléculaire et Cellulaire, 67400 Illkirch, France; Centre National de la Recherche Scientifique, UMR 7104, 67400 Illkirch, France; Institut National de la Santé et de la Recherche Médicale, UMR, S 1258, 67400 Illkirch, France; Université de Strasbourg, IGBMC UMR 7104- UMR-S 1258, 67400 Illkirch, France., Sommer A; Macrophages and endothelial cells unit, Department of Developmental and Stem Cell Biology, Institut Pasteur, Université Paris Cité, UMR3738 CNRS, 75015 Paris, France; Sorbonne Université, Collège doctoral, 75005 Paris, France., AlHajj Hassan Z; IGBMC, Institut de Génétique et de Biologie Moléculaire et Cellulaire, 67400 Illkirch, France; Centre National de la Recherche Scientifique, UMR 7104, 67400 Illkirch, France; Institut National de la Santé et de la Recherche Médicale, UMR, S 1258, 67400 Illkirch, France; Université de Strasbourg, IGBMC UMR 7104- UMR-S 1258, 67400 Illkirch, France., Garcia Rodriguez C; Macrophages and endothelial cells unit, Department of Developmental and Stem Cell Biology, Institut Pasteur, Université Paris Cité, UMR3738 CNRS, 75015 Paris, France; Sorbonne Université, Collège doctoral, 75005 Paris, France., Adé K; Macrophages and endothelial cells unit, Department of Developmental and Stem Cell Biology, Institut Pasteur, Université Paris Cité, UMR3738 CNRS, 75015 Paris, France., Cattenoz P; IGBMC, Institut de Génétique et de Biologie Moléculaire et Cellulaire, 67400 Illkirch, France; Centre National de la Recherche Scientifique, UMR 7104, 67400 Illkirch, France; Institut National de la Santé et de la Recherche Médicale, UMR, S 1258, 67400 Illkirch, France; Université de Strasbourg, IGBMC UMR 7104- UMR-S 1258, 67400 Illkirch, France., Delaporte C; IGBMC, Institut de Génétique et de Biologie Moléculaire et Cellulaire, 67400 Illkirch, France; Centre National de la Recherche Scientifique, UMR 7104, 67400 Illkirch, France; Institut National de la Santé et de la Recherche Médicale, UMR, S 1258, 67400 Illkirch, France; Université de Strasbourg, IGBMC UMR 7104- UMR-S 1258, 67400 Illkirch, France., Gomez Perdiguero E; Macrophages and endothelial cells unit, Department of Developmental and Stem Cell Biology, Institut Pasteur, Université Paris Cité, UMR3738 CNRS, 75015 Paris, France. Electronic address: elisa.gomez-perdiguero@pasteur.fr., Giangrande A; IGBMC, Institut de Génétique et de Biologie Moléculaire et Cellulaire, 67400 Illkirch, France; Centre National de la Recherche Scientifique, UMR 7104, 67400 Illkirch, France; Institut National de la Santé et de la Recherche Médicale, UMR, S 1258, 67400 Illkirch, France; Université de Strasbourg, IGBMC UMR 7104- UMR-S 1258, 67400 Illkirch, France. Electronic address: angela@igbmc.fr.

المصدر: Developmental cell [Dev Cell] 2024 May 20; Vol. 59 (10), pp. 1284-1301.e8. Date of Electronic Publication: 2024 Apr 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101120028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1551 (Electronic) Linking ISSN: 15345807 NLM ISO Abbreviation: Dev Cell Subsets: MEDLINE

مواضيع طبية MeSH: Hematopoiesis*/physiology , Macrophages*/metabolism , Hematopoietic Stem Cells*/cytology , Hematopoietic Stem Cells*/metabolism, Animals ; Mice ; Phagocytosis/physiology ; Drosophila melanogaster ; Extracellular Matrix/metabolism ; Drosophila ; Cell Differentiation

المؤلفون: Sadeghi M; Department of Medicine, McGill University Health Centre, McGill International TB Centre, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada.; Department of Microbiology & Immunology, McGill University Health Centre, McGill International TB Centre, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada., Divangahi M; Department of Medicine, McGill University Health Centre, McGill International TB Centre, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada.; Department of Microbiology & Immunology, McGill University Health Centre, McGill International TB Centre, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada.; Department of Pathology, McGill University Health Centre, McGill International TB Centre, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada.

المصدر: Immunological reviews [Immunol Rev] 2024 May; Vol. 323 (1), pp. 186-196. Date of Electronic Publication: 2024 Apr 02.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Blackwell Country of Publication: England NLM ID: 7702118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-065X (Electronic) Linking ISSN: 01052896 NLM ISO Abbreviation: Immunol Rev Subsets: MEDLINE

مواضيع طبية MeSH: Immunity, Innate* , Immunologic Memory* , Hematopoietic Stem Cells*/metabolism , Hematopoietic Stem Cells*/immunology , Adaptive Immunity*, Animals ; Humans ; Signal Transduction ; Cell Differentiation ; Epigenesis, Genetic ; Cell Lineage ; Trained Immunity

المؤلفون: Xu J; Division of Hematology and Oncology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15232, USA.; UPMC Hillman Cancer Center, Pittsburgh, PA 15213, USA., Fei P; Cancer Biology, University of Hawaii Cancer Center, University of Hawaii, Honolulu, HI 96812, USA., Simon DW; Department of Critical Care Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Morowitz MJ; Department of Surgery, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Mehta PA; Division of Blood and Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Du W; Division of Hematology and Oncology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15232, USA.; UPMC Hillman Cancer Center, Pittsburgh, PA 15213, USA.

المصدر: Cells [Cells] 2024 Apr 24; Vol. 13 (9). Date of Electronic Publication: 2024 Apr 24.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

مواضيع طبية MeSH: Hematopoietic Stem Cells*/metabolism , Hematopoietic Stem Cells*/cytology , DNA Repair* , DNA Damage*, Humans ; Animals ; Genomic Instability ; Energy Metabolism ; Oxidative Phosphorylation

المؤلفون: Lu Z; Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI.; Carbone Cancer Center, University of Wisconsin, Madison, WI.; Wisconsin Blood Cancer Research Institute, University of Wisconsin, Madison, WI., Wang Y; Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI.; Carbone Cancer Center, University of Wisconsin, Madison, WI.; Wisconsin Blood Cancer Research Institute, University of Wisconsin, Madison, WI., Assumpção ALFV; Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI.; Carbone Cancer Center, University of Wisconsin, Madison, WI.; Wisconsin Blood Cancer Research Institute, University of Wisconsin, Madison, WI., Liu P; Carbone Cancer Center, University of Wisconsin, Madison, WI.; Department of Biostatistics and Medical Informatics, University of Wisconsin School of Medicine and Public Health, Madison, WI., Kopp A; Wisconsin Blood Cancer Research Institute, University of Wisconsin, Madison, WI.; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI., Saka S; Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI.; Carbone Cancer Center, University of Wisconsin, Madison, WI.; Wisconsin Blood Cancer Research Institute, University of Wisconsin, Madison, WI., Mcilwain SJ; Carbone Cancer Center, University of Wisconsin, Madison, WI.; Department of Biostatistics and Medical Informatics, University of Wisconsin School of Medicine and Public Health, Madison, WI., Viny AD; Division of Hematology & Oncology, Department of Medicine, Columbia University Irving Medical Center, New York, NY.; Columbia Stem Cell Initiative, Columbia University Irving Medical Center, New York, NY.; Department of Genetics & Development, Columbia University Irving Medical Center, New York, NY., Brand M; Wisconsin Blood Cancer Research Institute, University of Wisconsin, Madison, WI.; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI., Pan X; Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI.; Carbone Cancer Center, University of Wisconsin, Madison, WI.; Wisconsin Blood Cancer Research Institute, University of Wisconsin, Madison, WI.

المصدر: Blood advances [Blood Adv] 2024 Jun 25; Vol. 8 (12), pp. 3076-3091.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

مواضيع طبية MeSH: Cell Cycle Proteins*/metabolism , Cell Cycle Proteins*/genetics , Chromosomal Proteins, Non-Histone*/metabolism , Chromosomal Proteins, Non-Histone*/genetics , Hematopoietic Stem Cells*/metabolism , Hematopoietic Stem Cells*/cytology , YY1 Transcription Factor*/metabolism , YY1 Transcription Factor*/genetics, Animals ; Mice ; Cohesins ; Gene Expression Regulation ; Hematopoiesis ; Mice, Knockout ; Promoter Regions, Genetic

المؤلفون: Serrano G; Computational Biology Program CIMA-Universidad de Navarra, Cancer Center Clínica Universidad de Navarra (CCUN), IdISNA, Pamplona, Spain.; Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia., Berastegui N; Hematology-Oncology Program, CIMA, Cancer Center Clínica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain.; Centro de Investigación Biomédica en Red de Cáncer, CIBERONC, Madrid, Spain., Díaz-Mazkiaran A; Computational Biology Program CIMA-Universidad de Navarra, Cancer Center Clínica Universidad de Navarra (CCUN), IdISNA, Pamplona, Spain.; Hematology-Oncology Program, CIMA, Cancer Center Clínica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain.; Centro de Investigación Biomédica en Red de Cáncer, CIBERONC, Madrid, Spain., García-Olloqui P; Hematology-Oncology Program, CIMA, Cancer Center Clínica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain.; Centro de Investigación Biomédica en Red de Cáncer, CIBERONC, Madrid, Spain., Rodriguez-Res C; Computational Biology Program CIMA-Universidad de Navarra, Cancer Center Clínica Universidad de Navarra (CCUN), IdISNA, Pamplona, Spain., Huerga-Dominguez S; Hematology and Cell Therapy Service, Cancer Center Clínica Universidad de Navarra (CCUN), IdISNA, Pamplona, Spain., Ainciburu M; Hematology-Oncology Program, CIMA, Cancer Center Clínica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain.; Centro de Investigación Biomédica en Red de Cáncer, CIBERONC, Madrid, Spain., Vilas-Zornoza A; Hematology-Oncology Program, CIMA, Cancer Center Clínica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain.; Centro de Investigación Biomédica en Red de Cáncer, CIBERONC, Madrid, Spain., Martin-Uriz PS; Hematology-Oncology Program, CIMA, Cancer Center Clínica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain., Aguirre-Ruiz P; Hematology-Oncology Program, CIMA, Cancer Center Clínica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain., Ullate-Agote A; Hematology-Oncology Program, CIMA, Cancer Center Clínica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain., Ariceta B; Hematology-Oncology Program, CIMA, Cancer Center Clínica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain.; Centro de Investigación Biomédica en Red de Cáncer, CIBERONC, Madrid, Spain., Lamo-Espinosa JM; Department of Orthopedics, Clínica Universidad de Navarra, Pamplona, Spain., Acha P; MDS Research Group, Josep Carreras Leukaemia Research Institut, Universitat Autònoma de Barcelona, Barcelona, Spain.; Service of Hematology, Hospital Universitari Vall d'Hebron, Barcelona; Vall d'Hebron Instituto de Oncología (VHIO), Barcelona, Spain., Calvete O; MDS Research Group, Josep Carreras Leukaemia Research Institut, Universitat Autònoma de Barcelona, Barcelona, Spain., Jimenez T; Centro de Investigación Biomédica en Red de Cáncer, CIBERONC, Madrid, Spain.; Department of Hematology, Hospital Universitario de Salamanca-IBSAL, Salamanca, Spain., Molero A; Service of Hematology, Hospital Universitari Vall d'Hebron, Barcelona; Vall d'Hebron Instituto de Oncología (VHIO), Barcelona, Spain., Montoro MJ; Service of Hematology, Hospital Universitari Vall d'Hebron, Barcelona; Vall d'Hebron Instituto de Oncología (VHIO), Barcelona, Spain., Díez-Campelo M; Centro de Investigación Biomédica en Red de Cáncer, CIBERONC, Madrid, Spain.; Department of Hematology, Hospital Universitario de Salamanca-IBSAL, Salamanca, Spain., Valcarcel D; Service of Hematology, Hospital Universitari Vall d'Hebron, Barcelona; Vall d'Hebron Instituto de Oncología (VHIO), Barcelona, Spain., Solé F; MDS Research Group, Josep Carreras Leukaemia Research Institut, Universitat Autònoma de Barcelona, Barcelona, Spain., Alfonso-Pierola A; Centro de Investigación Biomédica en Red de Cáncer, CIBERONC, Madrid, Spain.; Hematology and Cell Therapy Service, Cancer Center Clínica Universidad de Navarra (CCUN), IdISNA, Pamplona, Spain., Ochoa I; Instituto de Ciencia de los Datos e Inteligencia Artificial (DATAI), University of Navarra, Pamplona, Spain.; Department of Electrical and Electronics engineering, School of Engineering (Tecnun), University of Navarra, Donostia, Spain., Prósper F; Hematology-Oncology Program, CIMA, Cancer Center Clínica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain. fprosper@unav.es.; Centro de Investigación Biomédica en Red de Cáncer, CIBERONC, Madrid, Spain. fprosper@unav.es.; Hematology and Cell Therapy Service, Cancer Center Clínica Universidad de Navarra (CCUN), IdISNA, Pamplona, Spain. fprosper@unav.es., Ezponda T; Hematology-Oncology Program, CIMA, Cancer Center Clínica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain. tezponda@unav.es.; Centro de Investigación Biomédica en Red de Cáncer, CIBERONC, Madrid, Spain. tezponda@unav.es., Hernaez M; Computational Biology Program CIMA-Universidad de Navarra, Cancer Center Clínica Universidad de Navarra (CCUN), IdISNA, Pamplona, Spain. mhernaez@unav.es.; Centro de Investigación Biomédica en Red de Cáncer, CIBERONC, Madrid, Spain. mhernaez@unav.es.; Instituto de Ciencia de los Datos e Inteligencia Artificial (DATAI), University of Navarra, Pamplona, Spain. mhernaez@unav.es.

المصدر: Nature communications [Nat Commun] 2024 Jun 20; Vol. 15 (1), pp. 5272. Date of Electronic Publication: 2024 Jun 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Lenalidomide*/pharmacology , Lenalidomide*/therapeutic use , Myelodysplastic Syndromes*/genetics , Myelodysplastic Syndromes*/drug therapy , Myelodysplastic Syndromes*/pathology , Myelodysplastic Syndromes*/metabolism , Hematopoietic Stem Cells*/drug effects , Hematopoietic Stem Cells*/metabolism , Antigens, CD34*/metabolism , Chromosome Deletion* , Chromosomes, Human, Pair 5*/genetics , Single-Cell Analysis*, Humans ; Male ; Female ; Aged ; Gene Regulatory Networks/drug effects ; Middle Aged ; Hematopoiesis/drug effects ; Hematopoiesis/genetics ; Transcriptome ; Aged, 80 and over ; RNA-Seq ; Gene Expression Profiling

المؤلفون: He M; Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology, Guangzhou, 510006, China., Li X; Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology, Guangzhou, 510006, China.; Laboratory of Developmental Biology, Department of Cell Biology and Genetics, School of Basic Medical Sciences, Chongqing Medical University, Chongqing, 400016, China., Xu B; Key Laboratory of Hebei Province for Molecular Biophysics, Institute of Biophysics, School of Health Science & Biomedical Engineering, Hebei University of Technology, Tianjin, 300130, China., Lu Y; Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology, Guangzhou, 510006, China., Lai J; Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology, Guangzhou, 510006, China., Ling Y; Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology, Guangzhou, 510006, China., Liu H; Vehicle Engineering, School of Mechanical and Automotive Engineering, South China University of Technology, Guangzhou, 510000, China., An Z; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, 510275, China., Zhang W; Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology, Guangzhou, 510006, China. mczhangwq@scut.edu.cn., Li F; Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology, Guangzhou, 510006, China. liff@scut.edu.cn.

المصدر: Stem cell research & therapy [Stem Cell Res Ther] 2024 Jun 18; Vol. 15 (1), pp. 172. Date of Electronic Publication: 2024 Jun 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE

مواضيع طبية MeSH: Zebrafish*/genetics , Hematopoietic Stem Cells*/metabolism , Hematopoietic Stem Cells*/cytology , Chromatin*/metabolism , Chromatin*/genetics, Animals ; Genome ; Zebrafish Proteins/genetics ; Zebrafish Proteins/metabolism ; Gene Expression Regulation, Developmental ; Cell Differentiation ; Proto-Oncogene Proteins ; Trans-Activators