يعرض 1 - 10 نتائج من 17 نتيجة بحث عن '"Henk L Granzier"', وقت الاستعلام: 0.90s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Late-life restoration of mitochondrial function reverses cardiac dysfunction in old mice

    المؤلفون: Ying Ann Chiao, Huiliang Zhang, Mariya Sweetwyne, Jeremy Whitson, Ying Sonia Ting, Nathan Basisty, Lindsay K Pino, Ellen Quarles, Ngoc-Han Nguyen, Matthew D Campbell, Tong Zhang, Matthew J Gaffrey, Gennifer Merrihew, Lu Wang, Yongping Yue, Dongsheng Duan, Henk L Granzier, Hazel H Szeto, Wei-Jun Qian, David Marcinek, Michael J MacCoss, Peter Rabinovitch

    المصدر: eLife, Vol 9 (2020)

    مصطلحات موضوعية: mitochondria, aging, cardiac function, oxidative stress, diastolic dysfunction, Medicine, Science, Biology (General), QH301-705.5

    وصف الملف: electronic resource

    Relation: https://elifesciences.org/articles/55513; https://doaj.org/toc/2050-084X

    URL الوصول: https://doaj.org/article/720f135c89f7440e948956a2b4dd4a5d

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  2. 2
    دورية أكاديمية
    Downsizing the molecular spring of the giant protein titin reveals that skeletal muscle titin determines passive stiffness and drives longitudinal hypertrophy

    المؤلفون: Ambjorn Brynnel, Yaeren Hernandez, Balazs Kiss, Johan Lindqvist, Maya Adler, Justin Kolb, Robbert van der Pijl, Jochen Gohlke, Joshua Strom, John Smith, Coen Ottenheijm, Henk L Granzier

    المصدر: eLife, Vol 7 (2018)

    مصطلحات موضوعية: biomechanics, muscle, myofilament function, elasticity, titinopathies, passive stiffness, Medicine, Science, Biology (General), QH301-705.5

    وصف الملف: electronic resource

    Relation: https://elifesciences.org/articles/40532; https://doaj.org/toc/2050-084X

    URL الوصول: https://doaj.org/article/8efda138908741c7b765607d2f5a2dd8

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  3. 3
    دورية أكاديمية
    HDAC6 modulates myofibril stiffness and diastolic function of the heart

    المؤلفون: Ying-Hsi Lin, Jennifer L. Major, Tim Liebner, Zaynab Hourani, Joshua G. Travers, Sara A. Wennersten, Korey R. Haefner, Maria A. Cavasin, Cortney E. Wilson, Mark Y. Jeong, Yu Han, Michael Gotthardt, Scott K. Ferguson, Amrut V. Ambardekar, Maggie P.Y. Lam, Chunaram Choudhary, Henk L. Granzier, Kathleen C. Woulfe, Timothy A. McKinsey

    المصدر: The Journal of Clinical Investigation, Vol 132, Iss 10 (2022)

    مصطلحات موضوعية: Cardiology, Medicine

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/1558-8238

    URL الوصول: https://doaj.org/article/150af97ede814fce977a15aa3d27a1dc

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  4. 4
    دورية أكاديمية
    Rbm20ΔRRM Mice, Expressing a Titin Isoform with Lower Stiffness, Are Protected from Mechanical Ventilation-Induced Diaphragm Weakness

    المؤلفون: Marloes van den Berg, Eva L. Peters, Robbert J. van der Pijl, Shengyi Shen, Leo M. A. Heunks, Henk L. Granzier, Coen A. C. Ottenheijm

    المصدر: International Journal of Molecular Sciences, Vol 23, Iss 24, p 15689 (2022)

    مصطلحات موضوعية: diaphragm weakness, mechanical ventilation, titin, sarcomere dysfunction, Biology (General), QH301-705.5, Chemistry, QD1-999

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/1422-0067/23/24/15689; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067

    URL الوصول: https://doaj.org/article/ef16f1dac81a40c68876286ad3172bfe

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  5. 5
    دورية أكاديمية
    Increased Expression of N2BA Titin Corresponds to More Compliant Myofibrils in Athlete’s Heart

    المؤلفون: Dalma Kellermayer, Bálint Kiss, Hedvig Tordai, Attila Oláh, Henk L. Granzier, Béla Merkely, Miklós Kellermayer, Tamás Radovits

    المصدر: International Journal of Molecular Sciences, Vol 22, Iss 20, p 11110 (2021)

    مصطلحات موضوعية: titin, athlete’s heart, cardiac myofibril, AFM, transverse stiffness, Biology (General), QH301-705.5, Chemistry, QD1-999

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/1422-0067/22/20/11110; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067

    URL الوصول: https://doaj.org/article/15d21017fc054e069ee63e897b0891c7

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  6. 6
    Rbm20

    المؤلفون: Marloes, van den Berg, Eva L, Peters, Robbert J, van der Pijl, Shengyi, Shen, Leo M A, Heunks, Henk L, Granzier, Coen A C, Ottenheijm

    المصدر: International journal of molecular sciences. 23(24)

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::7af0b71f13dc71c2aa0e6df33dfdc423
    https://pubmed.ncbi.nlm.nih.gov/36555335

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  7. 7
    Abstract 13431: Gain-of-Function Mutations in RNA Binding Motif 20 Result in Cardiac Remodelling and Pathogenesis in Mice

    المؤلفون: Yanghai Zhang, Chunyan Wang, Mei Methawasin, Camila U Braz, Jeffrey Gao-Hu, Betty Yang, Joshua Strom, Timothy A Hacker, Hasan Khatib, Henk L Granzier, Wei Guo

    المصدر: Circulation. 144

    مصطلحات موضوعية: Physiology (medical), Cardiology and Cardiovascular Medicine

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::26b61f856fa7127e1e296b1b07ceabed
    https://doi.org/10.1161/circ.144.suppl_1.13431

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  8. 8
    Deleting Titin’s C-Terminal PEVK Exons Increases Passive Stiffness, Alters Splicing, and Induces Cross-Sectional and Longitudinal Hypertrophy in Skeletal Muscle

    المؤلفون: Robbert J. van der Pijl, Brian Hudson, Tomotaroh Granzier-Nakajima, Frank Li, Anne M. Knottnerus, John Smith, Charles S. Chung, Michael Gotthardt, Henk L. Granzier, Coen A. C. Ottenheijm

    المساهمون: Physiology, ACS - Pulmonary hypertension & thrombosis, ACS - Heart failure & arrhythmias

    المصدر: Frontiers in Physiology, Vol 11 (2020)
    Frontiers in Physiology, 11:494. Frontiers Research Topics
    Frontiers in Physiology
    van der Pijl, R J, Hudson, B, Granzier-Nakajima, T, Li, F, Knottnerus, A M, Smith, J, Chung, C S, Gotthardt, M, Granzier, H L & Ottenheijm, C A C 2020, ' Deleting Titin’s C-Terminal PEVK Exons Increases Passive Stiffness, Alters Splicing, and Induces Cross-Sectional and Longitudinal Hypertrophy in Skeletal Muscle ', Frontiers in Physiology, vol. 11, 494 . https://doi.org/10.3389/fphys.2020.00494

    مصطلحات موضوعية: 0301 basic medicine, Gene isoform, RNA splicing, Physiology, 030204 cardiovascular system & hematology, Sarcomere, lcsh:Physiology, Muscle hypertrophy, 03 medical and health sciences, Exon, 0302 clinical medicine, Physiology (medical), medicine, titin, Original Research, Soleus muscle, biology, lcsh:QP1-981, Chemistry, Skeletal muscle, musculoskeletal system, passive tension, 030104 developmental biology, medicine.anatomical_structure, biology.protein, Biophysics, Titin, hypertrophy, PEVK region

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c926c7716b595c4d0cd5e783d7101c5d
    https://www.frontiersin.org/article/10.3389/fphys.2020.00494/full

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  9. 9
    Author response: Downsizing the molecular spring of the giant protein titin reveals that skeletal muscle titin determines passive stiffness and drives longitudinal hypertrophy

    المؤلفون: Ambjorn Brynnel, Yaeren Hernandez, Balazs Kiss, Johan Lindqvist, Maya Adler, Justin Kolb, Robbert van der Pijl, Jochen Gohlke, Joshua Strom, John Smith, Coen Ottenheijm, Henk L Granzier

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d6a436c180599e01fe075a057a1ffdaf
    https://doi.org/10.7554/elife.40532.028

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  10. 10
    Abstract 215: The Role of Titin in Cardiac Function: Studies in Two Genetically Engineered Mouse Models With Disparate Titin’s Size

    المؤلفون: Mei Methawasin, Kirk R Hutchinson, John E Smith, Henk L Granzier

    المصدر: Circulation Research. 117

    مصطلحات موضوعية: animal structures, Physiology, macromolecular substances, musculoskeletal system, Cardiology and Cardiovascular Medicine

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c65f8270fdf00a890c6d995236e80a42
    https://doi.org/10.1161/res.117.suppl_1.215

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