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1دورية أكاديمية
المؤلفون: Tony Muchamuel, R. Andrea Fan, Janet L. Anderl, Darrin J. Bomba, Henry W. B. Johnson, Eric Lowe, Brian B. Tuch, Dustin L. McMinn, Beatriz Millare, Christopher J. Kirk
المصدر: Frontiers in Immunology, Vol 14 (2023)
مصطلحات موضوعية: immunoproteasome, plasma cells, lupus nephritis (LN), SLE - systemic lupus erythematosus, autoimmunity, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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المؤلفون: Jun Li, Shaobo Hu, Henry W B Johnson, Christopher J Kirk, Peng Xian, Yanping Song, Yuan Li, Nan Liu, Marcus Groettrup, Michael Basler
المصدر: Cardiovascular Research. 119:1030-1045
مصطلحات موضوعية: Physiology, Physiology (medical), Cardiology and Cardiovascular Medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a30bb611e747a9bebc2c1012383841f
https://doi.org/10.1093/cvr/cvac181 -
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المؤلفون: Erin Bradley, Lisa M. Kelly, Janet L. Anderl, Eric Lowe, David C. Moebius, Jeffrey Jones, Shirin Arastu-Kapur, Christopher J. Kirk, Henry W. B. Johnson, John Bui, Zhengping Wang, Dustin McMinn, Tony Muchamuel
المصدر: ACS Medicinal Chemistry Letters. 8:413-417
مصطلحات موضوعية: 0301 basic medicine, Multicatalytic endopeptidase complex, Molecular mass, Chemistry, Bortezomib, Protein subunit, Organic Chemistry, Highly selective, Biochemistry, Low molecular mass polypeptide-2, Carfilzomib, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, In vivo, Drug Discovery, medicine, medicine.drug
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المؤلفون: Henry W B, Johnson, Eric, Lowe, Janet L, Anderl, Andrea, Fan, Tony, Muchamuel, Simeon, Bowers, David C, Moebius, Christopher, Kirk, Dustin L, McMinn
المصدر: Journal of medicinal chemistry. 61(24)
مصطلحات موضوعية: Mice, Inbred BALB C, Proteasome Endopeptidase Complex, Morpholines, Anti-Inflammatory Agents, Non-Steroidal, Arthritis, Experimental, Arthritis, Rheumatoid, Cysteine Endopeptidases, Structure-Activity Relationship, Cell Line, Tumor, Drug Design, Animals, Cytokines, Humans, Administration, Intravenous, Female, Oligopeptides, Proteasome Inhibitors
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المؤلفون: Henry W. B. Johnson, Jon D. Rainier, Utpal Majumder
المصدر: Chemistry - A European Journal. 12:1747-1753
مصطلحات موضوعية: chemistry.chemical_classification, Thioketal, Longest linear sequence, Chemistry, Stereochemistry, Protein subunit, Organic Chemistry, Total synthesis, Esters, General Medicine, General Chemistry, Ring (chemistry), Metathesis, Catalysis, Ciguatoxins, Coupling (electronics), chemistry.chemical_compound, Cyclization, Ethers, Cyclic, Yield (chemistry), Enol ether, Indicators and Reagents, Polycyclic Compounds
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المصدر: Tetrahedron. 58:1997-2009
مصطلحات موضوعية: Coupling (electronics), C glycosides, Annulation, Ring-closing metathesis, Stereochemistry, Chemistry, Organic Chemistry, Drug Discovery, Biochemistry
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المصدر: ChemInform. 33
مصطلحات موضوعية: C glycosides, Coupling (electronics), Annulation, Ring-closing metathesis, Chemistry, Salt metathesis reaction, General Medicine, Combinatorial chemistry
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المؤلفون: Henry W. B. Johnson, Dirk J. Snyders, Jan Tytgat, Ivan Kopljar, Jon D. Rainier, Alain J. Labro, Eva Cuypers
المصدر: Proceedings of the National Academy of Sciences of the United States of America
مصطلحات موضوعية: Models, Molecular, Ciguatoxin, Stereochemistry, Molecular Sequence Data, Gating, polycyclic ether toxin, kv3.1, state, Ciguatoxins, k+ channel, neurotoxin site 5, sodium-channels, Neurotoxin, gated potassium channels, Amino Acid Sequence, Binding site, ciguatera, block, Multidisciplinary, Binding Sites, Sequence Homology, Amino Acid, Chemistry, Sodium channel, Pharmacology. Therapy, Depolarization, voltage sensors, Biological Sciences, potassium channels, Potassium channel, inhibition, Potassium Channels, Voltage-Gated, rat sensory neurons, Biophysics, derivatives, Marine Toxins, Marine toxin
وصف الملف: pdf; Print-Electronic; application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec230487a59784e4781344a812b1ed0e
https://pubmed.ncbi.nlm.nih.gov/19482941 -
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المصدر: The Journal of pharmacology and experimental therapeutics. 323(1)
مصطلحات موضوعية: Cell Survival, Inhibitory postsynaptic potential, Sodium Channels, Ciguatoxins, Rats, Sprague-Dawley, Brevetoxin, Ethers, Cyclic, Cerebellum, medicine, Neurotoxin, Animals, Polycyclic Compounds, Cells, Cultured, Pharmacology, Neurons, Binding Sites, biology, Molecular Structure, Sodium channel, Oxocins, Antagonist, Neurotoxicity, biology.organism_classification, medicine.disease, Gambierdiscus toxicus, Rats, Biochemistry, Animals, Newborn, Biophysics, Molecular Medicine, Calcium, Marine Toxins, Marine toxin, Sodium Channel Blockers, Synaptosomes
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763613eb7b6055694441710a3e8bcb89
https://pubmed.ncbi.nlm.nih.gov/17609421 -
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المؤلفون: Jon D. Rainier, Henry W. B. Johnson, Jason M. Cox, Utpal Majumder
المصدر: Chemistry (Weinheim an der Bergstrasse, Germany). 12(6)
مصطلحات موضوعية: C glycosides, Magnetic Resonance Spectroscopy, Stereochemistry, Ether, Metathesis, Ring (chemistry), Catalysis, Stereocenter, Ciguatoxins, chemistry.chemical_compound, Ethers, Cyclic, Glycosyl, Polycyclic Compounds, Glycosides, Organic Chemistry, Total synthesis, Ciguatera Poisoning, General Medicine, General Chemistry, Enol, chemistry, Cyclization, Epoxy Compounds, Indicators and Reagents, Marine Toxins, Ethers