المؤلفون: Smith, David A., Fernandez-Antunez, Carlota, Magri, Andrea, Bowden, Rory, Chaturvedi, Nimisha, Fellay, Jacques, McLauchlan, John, Foster, Graham R., Irving, William L., Simmonds, Peter, Pedergnana, Vincent, Ramirez, Santseharay, Bukh, Jens, Barnes, Eleanor, Ansari, M. Azim, Ball, Jonathan, Brainard, Diana, Burgess, Gary, Cooke, Graham, Dillon, John, Gore, Charles, Guha, Neil, Halford, Rachel, Herath, Cham, Holmes, Chris, Howe, Anita, Hudson, Emma, Irving, William, Khakoo, Salim, Klenerman, Paul, Koletzki, Diana, Martin, Natasha, Massetto, Benedetta, Mbisa, Tamyo, McHutchison, John, McKeating, Jane, Miners, Alec, Murray, Andrea, Shaw, Peter, Spencer, Chris C. A., Targett-Adams, Paul, Thomson, Emma, Vickerman, Peter, Zitzmann, Nicole

المساهمون: Nuffield Department of Medicine [Oxford, UK] (Big Data Institute), University of Oxford, University of Copenhagen = Københavns Universitet (UCPH), The Wellcome Trust Centre for Human Genetics [Oxford], Ecole Polytechnique Fédérale de Lausanne (EPFL), Université de Lausanne = University of Lausanne (UNIL), Swiss Institute of Bioinformatics [Lausanne] (SIB), Centre Hospitalier Universitaire Vaudois [Lausanne] (CHUV), University of Glasgow, Queen Mary University of London (QMUL), University of Nottingham, UK (UON), Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), STOP-HCV Consortium, Ball, J., Brainard, D., Burgess, G., Cooke, G., Dillon, J., Gore, C., Guha, N., Halford, R., Herath, C., Holmes, C., Howe, A., Hudson, E., Irving, W., Khakoo, S., Klenerman, P., Koletzki, D., Martin, N., Massetto, B., Mbisa, T., McHutchison, J., McKeating, J., Miners, A., Murray, A., Shaw, P., Spencer, CCA, Targett-Adams, P., Thomson, E., Vickerman, P., Zitzmann, N.

المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
STOP-HCV Consortium 2021, ' Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure ', Nature Communications, vol. 12, no. 1, 6105 . https://doi.org/10.1038/s41467-021-25649-6
Nature Communications, 2021, 12 (1), pp.6105. ⟨10.1038/s41467-021-25649-6⟩
Nature communications, vol. 12, no. 1, pp. 6105

مصطلحات موضوعية: ns2, Sofosbuvir, [SDV]Life Sciences [q-bio], viruses, General Physics and Astronomy, Genome-wide association study, resistance-associated substitutions, Hepacivirus, Viral Nonstructural Proteins, Chronic liver disease, medicine.disease_cause, chemistry.chemical_compound, 0302 clinical medicine, Treatment Failure, 0303 health sciences, Multidisciplinary, Hepatitis C virus, virus diseases, Viral Load, Antivirals, 3. Good health, Hepatocellular carcinoma, 030211 gastroenterology & hepatology, Viral load, medicine.drug, Genotype, ribavirin, Science, Genome, Viral, Antiviral Agents/therapeutic use, Genome, Viral/genetics, Hepacivirus/drug effects, Hepacivirus/genetics, Hepacivirus/isolation & purification, Hepatitis C, Chronic/drug therapy, Hepatitis C, Chronic/virology, Humans, Polymorphism, Genetic, Sofosbuvir/therapeutic use, Viral Load/drug effects, Viral Load/genetics, Viral Nonstructural Proteins/genetics, Antiviral Agents, General Biochemistry, Genetics and Molecular Biology, Article, Virus, 03 medical and health sciences, medicine, Potency, emergence, 030304 developmental biology, NS3, business.industry, Ribavirin, General Chemistry, biochemical phenomena, metabolism, and nutrition, Hepatitis C, Chronic, medicine.disease, Virology, infection, digestive system diseases, chemistry, Viral infection, protein, business

وصف الملف: PDF; text; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c9cf99c929fe18ff1ccaeb9a812b730

المؤلفون: Zator, Zachary A., Chung, Raymond T.

المصدر: Current HIV/AIDS Reports. December 2013 10(4):428-435

المؤلفون: Marc Hazzan, Sébastien Dharancy, Christophe Legendre, Hélène Fontaine, Alain Duhamel, Nassim Kamar, Benjamin Legendre, Stanislas Pol, Corinne Antoine, Philippe Mathurin, Alexandre Louvet, Laurent Alric, Julien Labreuche

المساهمون: Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Physiopathologie du système immunitaire (Inserm U1223), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Pharmacochimie et Biologie pour le Développement (PHARMA-DEV), Institut de Recherche pour le Développement (IRD)-Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), Unité de biostatistiques, CRLCC Val d'Aurelle - Paul Lamarque, Physiopathologie des Maladies Inflammatoires de l'Intestin, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Droit et Santé, Service des Maladies de l'Appareil Digestif et de la Nutrition [CHRU Lille], Hôpital Claude Huriez [Lille], CHU Lille-CHU Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Agence de la biomédecine [Saint-Denis la Plaine], Service Néphrologie et transplantation rénale Adultes [CHU Necker], CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de Néphrologie et Transplantation rénale [CHRU-lille], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Service de Néphrologie - Immunologie Clinique [Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-PRES Université de Toulouse, Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie de Toulouse (ICT-FR 2599), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Institut de Chimie du CNRS (INC)-Institut de Recherche pour le Développement (IRD), Unité fonctionnelle d’éthique et médecine légale [AP-HP Hôpital Necker Enfants malades], Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse]

المصدر: Journal of Hepatology
Journal of Hepatology, 2019, 70 (5), pp.831-838. ⟨10.1016/j.jhep.2018.12.036⟩
Journal of Hepatology, Elsevier, 2019, 70 (5), pp.831-838. ⟨10.1016/j.jhep.2018.12.036⟩

مصطلحات موضوعية: Male, 0301 basic medicine, MESH: Antiviral Agents / therapeutic use, Kidney transplant recipients, [SDV]Life Sciences [q-bio], MESH: Hepatitis B, Chronic / virology, Hepacivirus, Virus Replication, medicine.disease_cause, Gastroenterology, 0302 clinical medicine, Interferon, MESH: Hepatitis C, Chronic / virology, Kidney transplantation, Graft Survival, MESH: Hepatitis B virus / drug effects, virus diseases, Middle Aged, MESH: Kidney Transplantation / mortality, Hepatitis B, Prognosis, MESH: Case-Control Studies, MESH: Hepatitis C, Chronic / drug therapy, 3. Good health, MESH: Hepacivirus / drug effects, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, [SDV.IMM]Life Sciences [q-bio]/Immunology, Female, 030211 gastroenterology & hepatology, medicine.drug, Adult, Hepatitis B virus, medicine.medical_specialty, MESH: Graft Survival, Hepatitis C virus, Antiviral Agents, Virus, 03 medical and health sciences, Hepatitis B, Chronic, MESH: Hepacivirus / physiology, Internal medicine, medicine, Humans, chronic hepatitis C, chronic hepatitis B, Hepatitis, Hepatology, business.industry, MESH: Adult, MESH: Hepatitis B virus / physiology, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, Hepatitis C, Chronic, medicine.disease, Kidney Transplantation, 030104 developmental biology, MESH: Virus Replication / drug effects, Viral replication, Case-Control Studies, business, MESH: Female, MESH: Hepatitis B, Chronic / drug therapy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4f9e412772509fd90466e2df10fb88
https://doi.org/10.1016/j.jhep.2018.12.036

المؤلفون: Falconer, Karolin

مصطلحات موضوعية: HIV-1 -- immunology, HIV Infections -- virology, HIV Infections -- immunology, HIV Infections -- complications, Hepatitis C, Chronic -- virology, Hepatitis C, Chronic -- immunology, Hepatitis C, Chronic -- complications, Viral Load, Antiviral Agents -- therapeutic use, HIV

URL الوصول: http://diss.kib.ki.se/2010/978-91-7409-762-7/

Degree: Diss. (sammanfattning) Stockholm : Karolinska institutet, 2010

المؤلفون: Lindström, Hannah Kim

مصطلحات موضوعية: Hepacivirus -- genetics, Hepacivirus -- physiology, Hepatitis C, chronic -- virology, Hepatitis C, chronic -- drug therapy, Viral proteins -- genetics, Viral proteins -- physiology, Virus replication, Viral nonstructural proteins -- genetics, Viral nonstructural proteins -- physiology

URL الوصول: http://diss.kib.ki.se/2006/91-7140-875-4/

Degree: Diss. (sammanfattning) Stockholm : Karolinska institutet, 2006

المؤلفون: Ralf Bartenschlager, Brett D. Lindenbach, Thomas Pietschmann, Jens Bukh, Volker Lohmann, Charles M. Rice, Robert Thimme, Takaji Wakita, Darius Moradpour, Michael Houghton, Thomas F. Baumert, Stanley M. Lemon

المساهمون: German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), German Centre for Infection Research (DZIF), Institut de Recherche sur les Maladies Virales et Hépatiques (IVH), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), L'Institut hospitalo-universitaire de Strasbourg (IHU Strasbourg), Institut National de Recherche en Informatique et en Automatique (Inria)-l'Institut de Recherche contre les Cancers de l'Appareil Digestif (IRCAD)-Les Hôpitaux Universitaires de Strasbourg (HUS)-La Fédération des Crédits Mutuels Centre Est (FCMCE)-L'Association pour la Recherche contre le Cancer (ARC)-La société Karl STORZ, Nouvel Hôpital Civil de Strasbourg, University of Copenhagen = Københavns Universitet (UCPH), University of Alberta, University of North Carolina [Chapel Hill] (UNC), University of North Carolina System (UNC), Yale School of Medicine [New Haven, Connecticut] (YSM), Heidelberg University, Université de Lausanne = University of Lausanne (UNIL), Helmholtz Centre for Infection Research (HZI), Rockefeller University [New York], University of Freiburg [Freiburg], National Institute of Infectious Diseases [Tokyo], univOAK, Archive ouverte, TwinCore, Zentrum für experimentelle und klinische Infektionsforchung GmbH, Feodor-Lynen-Str.7, 30625 Hannover, Germany.

المصدر: Virus research, vol. 248, pp. 53-62
Bartenschlager, R, Baumert, T F, Bukh, J, Houghton, M, Lemon, S M, Lindenbach, B D, Lohmann, V, Moradpour, D, Pietschmann, T, Rice, C M, Thimme, R & Wakita, T 2018, ' Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy : Considerations for scientists and funding agencies ', Virus Research, vol. 248, pp. 53-62 . https://doi.org/10.1016/j.virusres.2018.02.016
Virus Research
Virus Research, 2018, 248, pp.53-62. ⟨10.1016/j.virusres.2018.02.016⟩
Virus research
Netherlands

مصطلحات موضوعية: 0301 basic medicine, Immune reconstitution, Cancer Research, Drug Resistance, Aucun, Hepacivirus, Antiviral Agents/pharmacology/therapeutic use, medicine.disease_cause, Hepacivirus/drug effects/physiology, HCV vaccine, Capital Financing, Translational Research, Biomedical, Liver disease, Chronic/drug therapy/prevention and control/*virology, Viral, Translational Medical Research, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Direct acting antiviral therapy, Antiviral therapy, Hepatitis C, Research Personnel, 3. Good health, Infectious Diseases, Workforce, Public Health, medicine.medical_specialty, Hepatitis C virus, Biology, Sciences du Vivant [q-bio]/Médecine humaine et pathologie, Hcv vaccine, Antiviral Agents, Virus, Antiviral Agents/pharmacology, Antiviral Agents/therapeutic use, Drug Resistance, Viral, Hepacivirus/drug effects, Hepacivirus/physiology, Hepatitis C, Chronic/drug therapy, Hepatitis C, Chronic/prevention & control, Hepatitis C, Chronic/virology, Humans, Research/economics, Research/manpower, Viral Vaccines/immunology, HCV research funding, 03 medical and health sciences, Chronic hepatitis, Virology, medicine, Intensive care medicine, Research, Viral Vaccines, Hepatitis C, Chronic, medicine.disease, 030104 developmental biology, Cancer risk, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6b05d87c7c36098f27aba8721d231f

المؤلفون: Ansari, M. Azim, Pedergnana, Vincent, Ip, Camilla L.C., Magri, Andrea, Von Delft, Annette, Bonsall, David, Chaturvedi, Nimisha, Bartha, Istvan, Smith, David, Nicholson, George, McVean, Gilean, Trebes, Amy, Piazza, Paolo, Fellay, Jacques, Cooke, Graham, Foster, Graham R., Hudson, Emma, McLauchlan, John, Simmonds, Peter, Bowden, Rory, Klenerman, Paul, Barnes, Eleanor, Spencer, Chris C.A., STOP-HCV Consortium

المساهمون: STOP-HCV Consortium, Barnes, E., Ball, J., Brainard, D., Burgess, G., Cooke, G., Dillon, J., Foster, G.R., Gore, C., Guha, N., Halford, R., Herath, C., Holmes, C., Howe, A., Hudson, E., Irving, W., Khakoo, S., Klenerman, P., Koletzki, D., Martin, N., Massetto, B., Mbisa, T., McHutchison, J., McKeating, J., McLauchlan, J., Miners, A., Murray, A., Shaw, P., Simmonds, P., Spencer, CCA, Targett-Adams, P., Thomson, E., Vickerman, P., Zitzmann, N., National Institute for Health Research, Medical Research Council (MRC), Medecins Sans Frontieres (MSF)

المصدر: Nature genetics
Nature genetics, vol. 49, no. 5, pp. 666-673

مصطلحات موضوعية: 0301 basic medicine, viruses, IL28B, Hepacivirus, Adaptive Immunity, Viral Nonstructural Proteins, medicine.disease_cause, HLA Antigens, INFECTION, WIDE ASSOCIATION, HCV CLEARANCE, Genetics & Heredity, Principal Component Analysis, GENETIC-VARIATION, virus diseases, 11 Medical And Health Sciences, Viral Load, Acquired immune system, 3. Good health, Host-Pathogen Interactions, Viral hepatitis, Viral load, Life Sciences & Biomedicine, INTERFERON, Genotype, Hepatitis C virus, Human leukocyte antigen, Genome, Viral, Biology, Adaptive Immunity/genetics, Alleles, Genetic Variation, Genome, Human/genetics, Genome, Viral/genetics, HLA Antigens/genetics, Hepacivirus/genetics, Hepacivirus/physiology, Hepatitis C, Chronic/genetics, Hepatitis C, Chronic/virology, Host-Pathogen Interactions/genetics, Humans, Immunity, Innate/genetics, Interleukins/genetics, Logistic Models, Viral Load/genetics, Viral Nonstructural Proteins/genetics, Article, 03 medical and health sciences, Immune system, DIRECT-ACTING ANTIVIRALS, Genetics, medicine, NS5A, Innate immune system, Science & Technology, Genome, Human, Interleukins, DISEASE ASSOCIATION, 06 Biological Sciences, Hepatitis C, Chronic, medicine.disease, Virology, Immunity, Innate, digestive system diseases, 030104 developmental biology, GENOTYPES 1, RESISTANCE, STOP-HCV Consortium, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd7b4a18157ec361570ab2d4df374b1e
http://ora.ox.ac.uk/objects/uuid:

المؤلفون: Julia, di Iulio, Angela, Ciuffi, Karen, Fitzmaurice, Dermot, Kelleher, Margalida, Rotger, Jacques, Fellay, Raquel, Martinez, Sara, Pulit, Hansjakob, Furrer, Huldrych F, Günthard, Manuel, Battegay, Enos, Bernasconi, Patrick, Schmid, Bernard, Hirschel, Eleanor, Barnes, Paul, Klenerman, Amalio, Telenti, Andri, Rauch, S, Yerly

المساهمون: Swiss HIV Cohort Study, Battegay, M., Bernasconi, E., Boni, J., Bucher, H., Burgisser, P., Calmy, A., Cattacin, S., Cavassini, M., Dubs, R., Egger, M., Elzi, L., Fischer, M., Flepp, M., Fontana, A., Francioli, P., Furrer, H., Fux, C., Gorgievski, M., Gu, H., Hirsch, H., Hirschel, B., Ho, I., Kahlert, C., Kaiser, L., Karrer, U., Kind, C., Klimkait, T., Ledergerber, B., Martinetti, G., Martinez, B., Mu, N., Nadal, D., Opravil, M., Paccaud, F., Pantaleo, G., Rauch, A., Regenass, S., Rickenbach, M., Rudin, C., Schmid, P., Schultze, D., Schupbach, J., Speck, R., Taffe, P., Telenti, A., Trkola, A., Vernazza, P., Weber, R., Yerly, S., University of Zurich, Telenti, A

المصدر: Hepatology, vol. 53, no. 5, pp. 1446-1454
Hepatology (Baltimore, Md.)

مصطلحات موضوعية: Genotype, Viral Hepatitis, Remission, Spontaneous, 610 Medicine & health, Single-nucleotide polymorphism, Hepacivirus, Biology, 10234 Clinic for Infectious Diseases, 03 medical and health sciences, 0302 clinical medicine, Genetic variation, Humans, Copy-number variation, Allele, Genotyping, 030304 developmental biology, Genetic association, Genetics, 0303 health sciences, Hepatology, Interleukins, Haplotype, Genetic Variation, Hepacivirus/physiology, Hepatitis C, Chronic/virology, Interleukins/genetics, Interleukins/physiology, Hepatitis C, Chronic, 3. Good health, Interleukin 28B, Immunology, 2721 Hepatology, 030211 gastroenterology & hepatology, Interferons

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16fc90157b6a90f0ff4f14a483e22289
https://doi.org/10.1002/hep.24263

المؤلفون: Probst, Aline Valeska, Dang, T, Bochud, Murielle, Egger, M, Negro, Francesco, Bochud, Pierre-Yves

المصدر: Journal of viral hepatitis
Cardiovascular and Metabolic Disorders, FBM Research Day, January 27, 2011, pp. 42
Journal of Viral Hepatitis, Vol. 18, No 11 (2011) pp. 745-59

مصطلحات موضوعية: ddc:616, Liver Cirrhosis, Liver Cirrhosis/pathology, Hepatitis C, Chronic/virology, Genotype, Review Literature as Topic, Meta-Analysis as Topic, Hepatitis C, Chronic/genetics/pathology, Biopsy, Liver Cirrhosis/pathology/virology, Hepacivirus, ddc:616.07, Hepatitis C, Chronic, Liver/virology, Cohort Studies, Liver, Risk Factors, Case-Control Studies, Hepacivirus/genetics/pathogenicity, Disease Progression, Odds Ratio, Humans

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::43a7fdf24c64c25d5c93833e5388f299

المؤلفون: Florian W. R. Vondran, Robert Thimme, Pascal Mutz, Oliver Grünvogel, Katharina Esser-Nobis, Volker Lohmann, Christoph Neumann-Haefelin, Daniel Gotthardt, Ji-Young Lee, Ralf Bartenschlager, Arianeb Mehrabi, Alexander H. Dalpke, Anna Reustle, Ombretta Colasanti, Volker Klöss, Marco Binder, Paul Schnitzler, Sandrine Belouzard, Ronald Koschny, Katrin Hoffmann, Jasper Hesebeck-Brinckmann, Jean Dubuisson

المساهمون: Heidelberg University, Department of Infectious Diseases [Heidelberg, Germany], Heidelberg University Hospital [Heidelberg], Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Universität Heidelberg [Heidelberg] = Heidelberg University, German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), Hannover Medical School [Hannover] (MHH), German Center for Infection Research [Heidelberg, Germany] (DZIF), University Hospital Freiburg, Albert-Ludwigs-Universität Freiburg, This project was supported by grants from the Deutsche Forschungsgemeinschaft (TRR179-TP17, FOR1202-TP3 to Volker Lohmann, TRR179-TP9, FOR1202-TP1 to Ralf Bartenschlager, TRR179-TP1 to Robert Thimme, and TRR179-TP2 to Christoph Neumann-Haefelin). This work was supported by a grant from the Excellence Cluster Cellular Networks of University of Heidelberg (to Alexander H. Dalpke and Volker Lohmann)., The authors thank Rahel Klein, Ulrike Herian, Uta Haselmann, and Jutta Mohr for excellent technical assistance and Vibor Laketa for microscopy support. We are grateful to the Electron Microscopy Core Facility of the University of Heidelberg for providing access to their equipment and thanks to Dr Charlotta Funaya and Dr Stefan Hillmer for technical support in electron microscopy work. A plasmid encoding TLR3 was a kind gift from T. Espevik, NTNU, Trondheim, Norway. In addition, we thank Daniel Lamarre for helpful discussions., Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Universität Heidelberg [Heidelberg]

المصدر: Gastroenterology
Gastroenterology, 2018, 154 (8), pp.2237-2251.e16. ⟨10.1053/j.gastro.2018.03.020⟩
Gastroenterology, WB Saunders, 2018, 154 (8), pp.2237-2251.e16. ⟨10.1053/j.gastro.2018.03.020⟩

مصطلحات موضوعية: MESH: RNA, Double-Stranded/isolation & purification, 0301 basic medicine, MESH: Immunity, Innate, MESH: Interferons/immunology, MESH: Toll-Like Receptor 3/metabolism, viruses, Hepacivirus, MESH: Hepatitis C, Chronic/virology, Virus Replication, Exosomes, medicine.disease_cause, [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity, Interferon, MESH: RNA, Double-Stranded/immunology, Toll-like receptor, MESH: Hepatocytes/metabolism, RIG-I, Gastroenterology, MDA5, 3. Good health, Cell biology, MESH: Interferons/metabolism, MESH: Host-Pathogen Interactions/immunology, Host-Pathogen Interactions, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, RNA, Viral, MESH: Extracellular Vesicles/metabolism, Signal Transduction, medicine.drug, MESH: Toll-Like Receptor 3/immunology, MESH: Hepatitis C, Chronic/blood, Hepatitis C virus, Primary Cell Culture, Biology, MESH: Virus Replication/immunology, Virus, Cell Line, MESH: Primary Cell Culture, Extracellular Vesicles, 03 medical and health sciences, MESH: RNA, Viral/isolation & purification, Virology, medicine, Humans, MESH: RNA, Viral/immunology, MESH: Extracellular Vesicles/immunology, RNA, Double-Stranded, MESH: Hepatitis C, Chronic/immunology, MESH: Humans, Hepatology, MESH: Hepatocytes/immunology, MESH: RNA, Viral/metabolism, MESH: Signal Transduction/immunology, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, Hepatitis C, Chronic, Immunity, Innate, Toll-Like Receptor 3, MESH: Cell Line, Escape, 030104 developmental biology, MESH: Hepacivirus/physiology, Viral replication, TLR3, Hepatocytes, Interferons, Rab27a, MESH: RNA, Double-Stranded/metabolism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cdb70da0420c330868ac469be32c258
https://doi.org/10.1053/j.gastro.2018.03.020