المؤلفون: Shi, Qing, Ornstein, Paul L., Briner, Karin, Richardson, Timothy I., Arnold, Macklin B., Backer, Ryan T., Buckmaster, Jennifer L., Canada, Emily J., Doecke, Christopher W., Hertel, Larry W., Honigschmidt, Nick, Hsiung, Hansen M., Husain, Saba, Kuklish, Steve L., Martinelli, Michael J., Mullaney, Jeffrey T., O’Brien, Thomas P., Reinhard, Matt R., Rothhaar, Roger, Shah, Jikesh, Wu, Zhipei, Xie, Chaoyu, Zgombick, John M., Fisher, Matthew J.

المصدر: In Bioorganic & Medicinal Chemistry Letters 2006 16(9):2341-2346

المؤلفون: Takeuchi, Kumiko, Kohn, Todd J, Honigschmidt, Nicholas A, Rocco, Vincent P, Spinazze, Patrick G, Atkinson, Steven T, Hertel, Larry W, Nelson, David L, Wainscott, D.Bradley, Ahmad, Laura J, Shaw, Janice, Threlkeld, Penny G, Wong, David T

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المؤلفون: Richardson, Frank C., Richardson, Katherine K., Kroin, Julian S., Hertel, Larry W.

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المؤلفون: Delia, Thomas J., Hertel, Larry W., Wittle, Larry W.

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المؤلفون: Richardson TI; Lilly Research Laboratories, A Division of Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana 46285, USA. timrich@lilly.com, Ornstein PL, Briner K, Fisher MJ, Backer RT, Biggers CK, Clay MP, Emmerson PJ, Hertel LW, Hsiung HM, Husain S, Kahl SD, Lee JA, Lindstrom TD, Martinelli MJ, Mayer JP, Mullaney JT, O'Brien TP, Pawlak JM, Revell KD, Shah J, Zgombick JM, Herr RJ, Melekhov A, Sampson PB, King CH

المصدر: Journal of medicinal chemistry [J Med Chem] 2004 Jan 29; Vol. 47 (3), pp. 744-55.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Piperazines/*chemical synthesis , Receptor, Melanocortin, Type 4/*agonists, Animals ; Binding, Competitive ; Biological Availability ; Cell Line ; Cyclic AMP/biosynthesis ; Humans ; Ligands ; Piperazines/chemistry ; Piperazines/pharmacology ; Radioligand Assay ; Rats ; Rats, Inbred F344 ; Receptor, Melanocortin, Type 4/metabolism ; Structure-Activity Relationship