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1دورية أكاديمية
المؤلفون: Justin S. Antony, Pascale Birrer, Claudia Bohnert, Sina Zimmerli, Petra Hillmann, Hervé Schaffhauser, Christine Hoeflich, Andreas Hoeflich, Ramzi Khairallah, Andreas T. Satoh, Isabelle Kappeler, Isabel Ferreira, Klaas P. Zuideveld, Friedrich Metzger
المصدر: Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102055- (2023)
مصطلحات موضوعية: MT: RNA/DNA Editing, IGF-I, mRNA therapy, muscle injury, disc herniation, regeneration, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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2
المؤلفون: Andreas Tosstorff, Markus G. Rudolph, Jason C. Cole, Michael Reutlinger, Christian Kramer, Hervé Schaffhauser, Agnès Nilly, Alexander Flohr, Bernd Kuhn
المصدر: Journal of Computer-Aided Molecular Design. 36:753-765
مصطلحات موضوعية: Machine Learning, Molecular Docking Simulation, Drug Discovery, Proteins, Physical and Theoretical Chemistry, Ligands, Protein Binding, Computer Science Applications
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3
المؤلفون: Alexander Flohr, Barbara Mueller, Hervé Schaffhauser, Roman Hutter, Claudia Bohnert, Mélanie Pellisson
المصدر: Bioorganicmedicinal chemistry letters. 27(24)
مصطلحات موضوعية: 0301 basic medicine, Clinical Biochemistry, Allosteric regulation, Drug Evaluation, Preclinical, Pharmaceutical Science, CHO Cells, Pharmacology, Muscarinic Agonists, Biochemistry, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, Cricetulus, Allosteric Regulation, Cricetinae, parasitic diseases, Drug Discovery, Muscarinic acetylcholine receptor, Animals, Humans, GABA-A Receptor Agonists, Molecular Biology, G protein-coupled receptor, Chemistry, Organic Chemistry, Receptor, Muscarinic M1, Muscarinic acetylcholine receptor M1, Receptors, GABA-A, 030104 developmental biology, Mutagenesis, Site-Directed, Molecular Medicine, 030217 neurology & neurosurgery
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4
المؤلفون: Thomas J. Connors, Jie Qian, Zeck Huang, Joanne R. Mathiasen, Edward R. Bacon, Thelma S. Angeles, Mark J. Huffman, Emir Duzic, Joseph M. Salvino, Beth Ann McKenna, Hervé Schaffhauser, Robert J. McHugh, Lily D. Lu, George C. Morton, Beverly P. Holskin, Karla Kopec, Amy DiCamillo, Gerard C. Rosse, Chrysanthe Spais, Rabindranath Tripathy, Lisa D. Aimone
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:1421-1426
مصطلحات موضوعية: Stereochemistry, Chemistry, Organic Chemistry, Clinical Biochemistry, Antagonist, Pharmaceutical Science, Stereoisomerism, Biochemistry, Sulfone, chemistry.chemical_compound, In vivo, Drug Discovery, 5-HT6 receptor, Molecular Medicine, Pharmacophore, Receptor, Molecular Biology, 5-HT receptor
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5
المؤلفون: Beverly P. Holskin, Karla Kopec, Joanne R. Mathiasen, Amy DiCamillo, Babu G. Sundar, Thomas J. Connors, Emir Duzic, Edward R. Bacon, Gerard C. Rosse, Chrysanthe Spais, Thomas R. Bailey, Beth Ann McKenna, Rebecca A. Brown, Jie Qian, Derek Dunn, Mark J. Huffman, Joseph M. Salvino, Huang Zeqi, Lisa D. Aimone, Hervé Schaffhauser, Deborah Galinis, Thelma S. Angeles, Lily D. Lu, George C. Morton
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:120-123
مصطلحات موضوعية: biology, Organic Chemistry, Clinical Biochemistry, hERG, Pharmaceutical Science, Pharmacology, Biochemistry, Social recognition, chemistry.chemical_compound, chemistry, Drug Discovery, biology.protein, 5-HT6 receptor, Molecular Medicine, Structure–activity relationship, Serotonin Antagonists, Penetrant (biochemical), Receptor, Molecular Biology, 5-HT receptor
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6
المؤلفون: Emir Duzic, Edward R. Bacon, Joanne R. Mathiasen, Michael J. Marino, Donna Bozyczko-Coyne, John A. Gruner, John P. Mallamo, Rita Raddatz, Dorothy G. Flood, Lisa D. Aimone, Hervé Schaffhauser, Siyuan Le, Maciej Gasior, Michael Williams, Mark A. Ator, Robert L. Hudkins
المصدر: Journal of Pharmacology and Experimental Therapeutics. 340:124-133
مصطلحات موضوعية: Pharmacology, Agonist, Chemistry, medicine.drug_class, Antagonist, Receptor antagonist, Dose–response relationship, chemistry.chemical_compound, medicine, Molecular Medicine, Inverse agonist, Receptor, Ex vivo, Histamine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d821744703207b55845570e2612fea8e
https://doi.org/10.1124/jpet.111.186585 -
7
المصدر: Journal of Neuroscience Methods. 185:70-75
مصطلحات موضوعية: Male, Histamine Antagonists, Pharmacology, Biology, Binding, Competitive, Sensitivity and Specificity, Rats, Sprague-Dawley, chemistry.chemical_compound, Organ Culture Techniques, Slice preparation, Predictive Value of Tests, Reference Values, In vivo, Ciproxifan, Image Processing, Computer-Assisted, medicine, Animals, Receptors, Histamine H3, Receptor, Brain Chemistry, Thioperamide, Dose-Response Relationship, Drug, General Neuroscience, Brain, Rats, chemistry, Autoradiography, Biological Assay, Histamine H3 receptor, Histamine, medicine.drug, ABT-239
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8
المصدر: Brain Research. 1227:42-51
مصطلحات موضوعية: Sarcosine, Morpholines, Blotting, Western, Glycine, Wortmannin, Phosphatidylinositol 3-Kinases, chemistry.chemical_compound, Glycine Plasma Membrane Transport Proteins, Pregnancy, Animals, Phosphatidylinositol, Enzyme Inhibitors, Phosphorylation, Molecular Biology, Cells, Cultured, Phosphoinositide-3 Kinase Inhibitors, Cerebral Cortex, Neurons, Alanine, biology, Kinase, General Neuroscience, Biological Transport, Immunohistochemistry, Molecular biology, Rats, Androstadienes, Amino Acid Transport Systems, Neutral, chemistry, Biochemistry, Chromones, Enzyme inhibitor, biology.protein, Female, Neurology (clinical), Uncompetitive inhibitor, Proto-Oncogene Proteins c-akt, Developmental Biology
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9
المؤلفون: Jeffrey McQuiston, Laura S. Lubbers, Lorrie P. Daggett, Theodore M. Kamenecka, Celine Bonnefous, Blake A. Rowe, Hervé Schaffhauser, Sylvia Morales
المصدر: Journal of Pharmacology and Experimental Therapeutics. 326:240-251
مصطلحات موضوعية: Male, Molecular Sequence Data, Biology, Receptors, Metabotropic Glutamate, Cell Line, Rats, Sprague-Dawley, Allosteric Regulation, Animals, Humans, Point Mutation, Amino Acid Sequence, Amino Acids, Cells, Cultured, Pharmacology, Metabotropic glutamate receptor 5, Metabotropic glutamate receptor 4, Metabotropic glutamate receptor 7, Metabotropic glutamate receptor 6, Rats, Amino Acid Substitution, Biochemistry, Metabotropic glutamate receptor, Molecular Medicine, Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 3, Metabotropic glutamate receptor 2, Allosteric Site, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75e3441ec046403faa6d68a072d2e96
https://doi.org/10.1124/jpet.108.138271 -
10
المؤلفون: Sandra M. Lechner, Guibao Gu, Linda J. Bristow, Daniel S. Lorrain, Hongbing Wei, Rebecca L. Cole, Lorrie P. Daggett, Xin Zhang, Hervé Schaffhauser
المصدر: Brain Research. 1197:47-62
مصطلحات موضوعية: Microdialysis, Blotting, Western, Thalamus, Gene Expression, Hippocampus, Receptors, Metabotropic Glutamate, Transfection, Amygdala, Prosencephalon, Limbic system, medicine, Animals, RNA, Messenger, Molecular Biology, In Situ Hybridization, Microscopy, Confocal, General Neuroscience, Central nucleus of the amygdala, Immunohistochemistry, Rats, medicine.anatomical_structure, Metabotropic receptor, nervous system, Metabotropic glutamate receptor, Forebrain, Neurology (clinical), Psychology, Neuroscience, Developmental Biology