المؤلفون: Waalewijn H; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands., Wasmann RE; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa., Bamford A; Medical Research Council Clinical Trials Unit, University College London, London, UK.; Infection, Immunity & Inflammation Department, UCL Great Ormond Street Hospital Institute of Child Health, London, UK., Gibb DM; Medical Research Council Clinical Trials Unit, University College London, London, UK., McIlleron HM; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.; Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa., Colbers A; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands., Burger DM; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands., Denti P; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

مؤلفون مشاركون: CHAPAS-4 trial team

المصدر: Journal of the Pediatric Infectious Diseases Society [J Pediatric Infect Dis Soc] 2024 Sep 26; Vol. 13 (9), pp. 496-500.

نوع المنشور: Journal Article; Randomized Controlled Trial

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 101586049 Publication Model: Print Cited Medium: Internet ISSN: 2048-7207 (Electronic) Linking ISSN: 20487193 NLM ISO Abbreviation: J Pediatric Infect Dis Soc Subsets: MEDLINE

مواضيع طبية MeSH: Pyridones*/pharmacokinetics , Heterocyclic Compounds, 3-Ring*/pharmacokinetics , Heterocyclic Compounds, 3-Ring*/therapeutic use , Heterocyclic Compounds, 3-Ring*/blood , Heterocyclic Compounds, 3-Ring*/administration & dosage , Oxazines*/pharmacokinetics , Piperazines*/pharmacokinetics , HIV Infections*/drug therapy , Anti-HIV Agents*/pharmacokinetics , Anti-HIV Agents*/therapeutic use , Anti-HIV Agents*/blood , Anti-HIV Agents*/administration & dosage, Humans ; Child ; Male ; Female ; Tenofovir/pharmacokinetics ; Tenofovir/therapeutic use ; Child, Preschool ; Adolescent ; Emtricitabine/pharmacokinetics ; Emtricitabine/therapeutic use ; Emtricitabine/administration & dosage ; Dideoxynucleosides/pharmacokinetics ; Dideoxynucleosides/therapeutic use ; Dideoxynucleosides/administration & dosage ; Lamivudine/pharmacokinetics ; Lamivudine/therapeutic use ; Lamivudine/administration & dosage ; HIV Integrase Inhibitors/pharmacokinetics ; HIV Integrase Inhibitors/therapeutic use ; HIV Integrase Inhibitors/administration & dosage ; Alanine/pharmacokinetics ; Alanine/analogs & derivatives ; Alanine/therapeutic use ; Biological Availability ; Drug Therapy, Combination ; Zidovudine/pharmacokinetics ; Zidovudine/therapeutic use ; Zidovudine/administration & dosage ; Adenine/analogs & derivatives ; Adenine/pharmacokinetics ; Adenine/therapeutic use ; Drug Interactions

المؤلفون: Choi D; Inflammatory Bowel Disease Center, University of Chicago Medicine, Chicago, IL.; Department of Pharmacy, University of Chicago Medicine, Chicago, IL, USA., Rubin DT; Inflammatory Bowel Disease Center, University of Chicago Medicine, Chicago, IL.; Department of Pharmacy, University of Chicago Medicine, Chicago, IL, USA., Man B; Department of Pharmacy, University of Chicago Medicine, Chicago, IL, USA.

المصدر: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists [Am J Health Syst Pharm] 2024 Sep 23; Vol. 81 (19), pp. e594-e600.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9503023 Publication Model: Print Cited Medium: Internet ISSN: 1535-2900 (Electronic) Linking ISSN: 10792082 NLM ISO Abbreviation: Am J Health Syst Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Heterocyclic Compounds, 3-Ring*/therapeutic use , Heterocyclic Compounds, 3-Ring*/administration & dosage, Humans ; Male ; Retrospective Studies ; Female ; Middle Aged ; Adult ; Inflammatory Bowel Diseases/drug therapy ; Time-to-Treatment ; Time Factors

المؤلفون: Huang L; Department of Pharmacology, The First People's Hospital of Shuangliu District, West China (Airport) Hospital of Sichuan University, Chengdu, China., Zhao D; Department of Pharmacology, The First People's Hospital of Shuangliu District, West China (Airport) Hospital of Sichuan University, Chengdu, China., Lin H; Department of Pharmacology, The First People's Hospital of Shuangliu District, West China (Airport) Hospital of Sichuan University, Chengdu, China., Zheng H; Department of Pharmacology, The First People's Hospital of Shuangliu District, West China (Airport) Hospital of Sichuan University, Chengdu, China., Li X; Department of Pharmacology, The First People's Hospital of Shuangliu District, West China (Airport) Hospital of Sichuan University, Chengdu, China., Chen L; Department of Pharmacology, The First People's Hospital of Shuangliu District, West China (Airport) Hospital of Sichuan University, Chengdu, China., Tang P; Department of TCM Pharmacy, Chengdu Integrated TCM and Western Medicine Hospital, Chengdu, China.

المصدر: Medicine [Medicine (Baltimore)] 2024 Sep 20; Vol. 103 (38), pp. e39826.

نوع المنشور: Journal Article; Systematic Review; Meta-Analysis

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE

مواضيع طبية MeSH: Dermatitis, Atopic*/drug therapy , Heterocyclic Compounds, 3-Ring*/therapeutic use , Heterocyclic Compounds, 3-Ring*/adverse effects , Heterocyclic Compounds, 3-Ring*/administration & dosage , Randomized Controlled Trials as Topic* , Severity of Illness Index*, Humans ; Adolescent ; Treatment Outcome ; Male ; Female

المؤلفون: Sambandan E; Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology (VIT), Vellore 632014, India., Thenmozhi K; Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology (VIT), Vellore 632014, India., Santosh G; Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology (VIT), Chennai 600127, India., Wang CC; School of Pharmacy, Kaohsiung Medical University, Kaohsiung City 807, Taiwan., Tsai PC; Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung City 807, Taiwan; Department of Computational Biology, Institute of Bioinformatics, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Chennai 602105, Tamil Nadu, India., Gurrani S; Department of Applied Science and Humanities, Invertis University, Bareilly, Uttar Pradesh, India., Senthilkumar S; Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology (VIT), Vellore 632014, India. Electronic address: senthilkumar.s@vit.ac.in., Chen YH; Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung City 807, Taiwan. Electronic address: jayshung1985@gmail.com., Ponnusamy VK; Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung City 807, Taiwan; Research Center for Precision Environmental Medicine, Kaohsiung Medical University, Kaohsiung City 807, Taiwan; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung City 807, Taiwan; Department of Chemistry, National Sun Yat-sen University (NSYSU), Kaohsiung City 804, Taiwan; Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung City 807, Taiwan. Electronic address: kumar@kmu.edu.tw.

المصدر: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2024 Sep 15; Vol. 1245, pp. 124275. Date of Electronic Publication: 2024 Aug 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101139554 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-376X (Electronic) Linking ISSN: 15700232 NLM ISO Abbreviation: J Chromatogr B Analyt Technol Biomed Life Sci Subsets: MEDLINE

مواضيع طبية MeSH: Heterocyclic Compounds, 3-Ring*/chemistry , Heterocyclic Compounds, 3-Ring*/analysis , Piperazines*/chemistry , Piperazines*/analysis , Pyridones*/chemistry , Pyridones*/analysis , Gas Chromatography-Mass Spectrometry*/methods , Oxazines*/chemistry , Limit of Detection* , Drug Contamination*, Reproducibility of Results ; Linear Models ; Mutagens/analysis ; Anti-HIV Agents/analysis ; Anti-HIV Agents/chemistry ; Liquid-Liquid Extraction/methods ; Sonication/methods ; Computer Simulation ; Humans

المؤلفون: Con D; Department of Gastroenterology, Austin Health, Heidelberg, VIC, Australia.; Department of Medicine, Austin Academic Centre, University of Melbourne, Melbourne, VIC, Australia., Hilley P; Department of Gastroenterology, Austin Health, Heidelberg, VIC, Australia.; Department of Medicine, Austin Academic Centre, University of Melbourne, Melbourne, VIC, Australia., Chin S; AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia., Corte C; AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia.; Faculty of Medicine and Health, Central Clinical School, University of Sydney, NSW, Australia., Hafeez B; Department of Medicine, Austin Academic Centre, University of Melbourne, Melbourne, VIC, Australia., Testro A; Department of Gastroenterology, Austin Health, Heidelberg, VIC, Australia.; Department of Medicine, Austin Academic Centre, University of Melbourne, Melbourne, VIC, Australia., De Cruz P; Department of Gastroenterology, Austin Health, Heidelberg, VIC, Australia.; Department of Medicine, Austin Academic Centre, University of Melbourne, Melbourne, VIC, Australia., Choy M; Department of Gastroenterology, Austin Health, Heidelberg, VIC, Australia.; Department of Medicine, Austin Academic Centre, University of Melbourne, Melbourne, VIC, Australia., Srinivasan A; Department of Gastroenterology, Austin Health, Heidelberg, VIC, Australia.; Department of Medicine, Austin Academic Centre, University of Melbourne, Melbourne, VIC, Australia.

المصدر: Journal of Crohn's & colitis [J Crohns Colitis] 2024 Sep 03; Vol. 18 (9), pp. 1505-1509.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 101318676 Publication Model: Print Cited Medium: Internet ISSN: 1876-4479 (Electronic) Linking ISSN: 18739946 NLM ISO Abbreviation: J Crohns Colitis Subsets: MEDLINE

مواضيع طبية MeSH: Liver Transplantation* , Janus Kinase Inhibitors*/therapeutic use , Janus Kinase Inhibitors*/adverse effects , Piperidines*/therapeutic use , Piperidines*/adverse effects , Pyrimidines*/therapeutic use , Pyrimidines*/adverse effects , Inflammatory Bowel Diseases*/drug therapy , Heterocyclic Compounds, 3-Ring*/therapeutic use , Heterocyclic Compounds, 3-Ring*/adverse effects, Humans ; Female ; Male ; Adult ; Middle Aged ; Immunosuppressive Agents/therapeutic use ; Immunosuppressive Agents/adverse effects ; Tacrolimus/therapeutic use ; Tacrolimus/adverse effects ; Australia ; Treatment Outcome ; Young Adult ; Pyrroles/therapeutic use ; Pyrroles/adverse effects ; Pyrroles/administration & dosage

المؤلفون: Gedefaw A; College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia. abel.degefaw.ali@ki.se.; Department of Global Public Health, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden. abel.degefaw.ali@ki.se., Tadesse BT; College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia., Berhan Y; St. Paul Millennium Medical College and Hospital, Addis Ababa, Ethiopia., Makonnen E; Department of Pharmacology and Clinical Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.; Center for Innovative Drug Development for Africa (CDT-Africa), College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia., Vella S; Department of Global Public Health, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden., Aklillu E; Department of Global Public Health, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden.

المصدر: BMC infectious diseases [BMC Infect Dis] 2024 Sep 02; Vol. 24 (1), pp. 901. Date of Electronic Publication: 2024 Sep 02.

نوع المنشور: Journal Article; Multicenter Study

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334 (Electronic) Linking ISSN: 14712334 NLM ISO Abbreviation: BMC Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Oxazines* , Heterocyclic Compounds, 3-Ring*/therapeutic use , Heterocyclic Compounds, 3-Ring*/adverse effects , Heterocyclic Compounds, 3-Ring*/administration & dosage , HIV Infections*/drug therapy , Pyridones* , Pregnancy Complications, Infectious*/drug therapy , Piperazines* , Pregnancy Outcome* , Infectious Disease Transmission, Vertical*/prevention & control, Humans ; Pregnancy ; Female ; Ethiopia/epidemiology ; Adult ; Retrospective Studies ; Infant, Newborn ; Young Adult ; Cyclopropanes ; Benzoxazines/therapeutic use ; Benzoxazines/adverse effects ; Anti-HIV Agents/therapeutic use ; Anti-HIV Agents/adverse effects ; Alkynes ; Cohort Studies ; Premature Birth/epidemiology

المؤلفون: Ye S; Department of Dermatology, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an, China., Yu B; Department of Dermatology, Taihe Hospital, Hubei University of Medicine, Shiyan, China., Wu J; Department of Dermatology, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an, China., Xu Z; Department of Dermatology, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an, China., Xu B; Department of Dermatology, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an, China., Sun H; Department of Neurology, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an, China., Zhao B; Department of Dermatology, Xi'an International Medical Center Hospital, Xi'an, China.

المصدر: Dermatitis : contact, atopic, occupational, drug [Dermatitis] 2024 Sep-Oct; Vol. 35 (5), pp. 537-539. Date of Electronic Publication: 2023 Dec 29.

نوع المنشور: Journal Article; Case Reports; Letter

بيانات الدورية: Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 101207335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-5220 (Electronic) Linking ISSN: 17103568 NLM ISO Abbreviation: Dermatitis Subsets: MEDLINE

مواضيع طبية MeSH: Psoriasis*/drug therapy , Heterocyclic Compounds, 3-Ring*/therapeutic use , Heterocyclic Compounds, 3-Ring*/adverse effects , Interleukin-17*/antagonists & inhibitors , Eczema*/drug therapy, Humans ; Janus Kinase 1/antagonists & inhibitors ; Janus Kinase Inhibitors/therapeutic use ; Antibodies, Monoclonal, Humanized/therapeutic use ; Antibodies, Monoclonal, Humanized/adverse effects ; Female

المؤلفون: De Greef A; Department of Dermatology, Cliniques universitaires Saint-Luc, Université catholique de Louvain (UCLouvain), Brussels, Belgium.; Institute of Experimental and Clinical Research (IREC), Pneumology, ENT and Dermatology Pole (LUNS), Université catholique de Louvain (UCLouvain), Brussels, Belgium., Peeters C; Department of Dermatology, Cliniques universitaires Saint-Luc, Université catholique de Louvain (UCLouvain), Brussels, Belgium., Dewit O; Department of Gastroenterology, Cliniques universitaires Saint-Luc, Université catholique de Louvain (UCLouvain), Brussels, Belgium.; Institute of Experimental and Clinical Research (IREC), Pole of Research in Hepato-Gastroenterology (GAEN), Université catholique de Louvain (UCLouvain), Brussels, Belgium., de Montjoye L; Department of Dermatology, Cliniques universitaires Saint-Luc, Université catholique de Louvain (UCLouvain), Brussels, Belgium.; Institute of Experimental and Clinical Research (IREC), Pneumology, ENT and Dermatology Pole (LUNS), Université catholique de Louvain (UCLouvain), Brussels, Belgium., Baeck M; Department of Dermatology, Cliniques universitaires Saint-Luc, Université catholique de Louvain (UCLouvain), Brussels, Belgium.; Institute of Experimental and Clinical Research (IREC), Pneumology, ENT and Dermatology Pole (LUNS), Université catholique de Louvain (UCLouvain), Brussels, Belgium.

المصدر: JAMA dermatology [JAMA Dermatol] 2024 Sep 01; Vol. 160 (9), pp. 1001-1003.

نوع المنشور: Case Reports; Journal Article

بيانات الدورية: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589530 Publication Model: Print Cited Medium: Internet ISSN: 2168-6084 (Electronic) Linking ISSN: 21686068 NLM ISO Abbreviation: JAMA Dermatol Subsets: MEDLINE

مواضيع طبية MeSH: Heterocyclic Compounds, 3-Ring*/therapeutic use , Heterocyclic Compounds, 3-Ring*/administration & dosage , Melkersson-Rosenthal Syndrome*/drug therapy , Melkersson-Rosenthal Syndrome*/diagnosis, Humans ; Treatment Outcome ; Male ; Female ; Pyridines/therapeutic use ; Pyridines/administration & dosage ; Adult

المؤلفون: Jin T; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China., Shao Y; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China., Xiao Z; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China., Zhu Y; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China., Shen Y; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China., Wang D; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China., Tang H; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.

المصدر: Dermatitis : contact, atopic, occupational, drug [Dermatitis] 2024 Sep-Oct; Vol. 35 (5), pp. 535-537. Date of Electronic Publication: 2024 Jan 09.

نوع المنشور: Case Reports; Letter; Journal Article

بيانات الدورية: Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 101207335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-5220 (Electronic) Linking ISSN: 17103568 NLM ISO Abbreviation: Dermatitis Subsets: MEDLINE

مواضيع طبية MeSH: Prurigo*/drug therapy , Prurigo*/etiology , Crohn Disease*/drug therapy , Crohn Disease*/complications , Heterocyclic Compounds, 3-Ring*/therapeutic use , Heterocyclic Compounds, 3-Ring*/adverse effects, Humans ; Female ; Adult

المؤلفون: Abrams EJ; ICAP at Columbia University, Mailman School of Public Health, Columbia University, New York, NY, United States of America.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, United States of America.; Department of Pediatrics, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, United States of America., Jao J; Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America., Madlala HP; Division of Epidemiology and Biostatistics, School of Public Health, University of Cape Town, Western Cape, Cape Town, South Africa., Zerbe A; ICAP at Columbia University, Mailman School of Public Health, Columbia University, New York, NY, United States of America., Catalano P; Maternal Infant Research Institute, Obstetrics and Gynecology Research, Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy, Tufts University School of Medicine, Tufts University, Boston, MA, United States of America., Gerschenson M; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, United States of America., Goedecke JH; Biomedical Research and Innovation Platform, South African Medical Research Council, Cape Town, South Africa.; Health through Physical Activity, Lifestyle and Sport Research Centre (HPALS), Division of Physiological Sciences, Department of Human Biology, University of Cape Town, Cape Town, South Africa., Gomba Y; Division of Epidemiology and Biostatistics, School of Public Health, University of Cape Town, Western Cape, Cape Town, South Africa., Josefson J; Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America., Kurland IJ; Department of Medicine, Stable Isotope and Metabolomics Core Facility, Albert Einstein College of Medicine, Bronx, NY, United States of America., Legbedze J; Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America., McComsey GA; University Hospitals Health System, Cleveland, OH, United States of America.; Department of Medicine and Pediatrics of Case Western Reserve University, Cleveland, OH, United States of America., Matyesini S; Division of Epidemiology and Biostatistics, School of Public Health, University of Cape Town, Western Cape, Cape Town, South Africa., Mukonda E; Division of Epidemiology and Biostatistics, School of Public Health, University of Cape Town, Western Cape, Cape Town, South Africa., Robinson D; Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America., Myer L; Division of Epidemiology and Biostatistics, School of Public Health, University of Cape Town, Western Cape, Cape Town, South Africa.

المصدر: PloS one [PLoS One] 2024 Aug 19; Vol. 19 (8), pp. e0307296. Date of Electronic Publication: 2024 Aug 19 (Print Publication: 2024).

نوع المنشور: Journal Article; Observational Study

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: HIV Infections*/drug therapy , Heterocyclic Compounds, 3-Ring*/adverse effects , Heterocyclic Compounds, 3-Ring*/therapeutic use , Piperazines*/adverse effects , Piperazines*/therapeutic use , Oxazines* , Pyridones*, Humans ; Female ; Pregnancy ; Adult ; Pregnancy Complications, Infectious/drug therapy ; Pregnancy Complications, Infectious/virology ; Prospective Studies ; HIV Integrase Inhibitors/adverse effects ; HIV Integrase Inhibitors/therapeutic use ; Child, Preschool ; Infant ; Infant, Newborn ; Obesity/chemically induced ; Obesity/epidemiology ; Insulin Resistance ; Male ; Weight Gain/drug effects ; Cohort Studies ; South Africa/epidemiology