المؤلفون: Lin BC; Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD, USA.; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, USA., Higgins NR; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, USA.; Program in Molecular Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Phung TH; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, USA., Monteiro MJ; Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD, USA.; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, USA.; Program in Molecular Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.

المصدر: The FEBS journal [FEBS J] 2022 Oct; Vol. 289 (20), pp. 6132-6153. Date of Electronic Publication: 2021 Jul 28.

نوع المنشور: Journal Article; Review; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE

مواضيع طبية MeSH: Amyotrophic Lateral Sclerosis*/metabolism , Frontotemporal Dementia*/genetics, Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Autophagy-Related Proteins/genetics ; Autophagy-Related Proteins/metabolism ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Mitochondrial Proteins/genetics ; Mutation ; Nuclear Proteins/genetics ; Proteasome Endopeptidase Complex/metabolism ; Ubiquitins/genetics ; Ubiquitins/metabolism

المؤلفون: Stanley TR; Department of Biomedical and Chemical Engineering and Sciences, Florida Institute of Technology, Melbourne, FL 32937, USA., Guisbert KSK; Department of Biomedical and Chemical Engineering and Sciences, Florida Institute of Technology, Melbourne, FL 32937, USA., Perez SM; Department of Biomedical and Chemical Engineering and Sciences, Florida Institute of Technology, Melbourne, FL 32937, USA., Oneka M; Department of Biomedical and Chemical Engineering and Sciences, Florida Institute of Technology, Melbourne, FL 32937, USA., Kernin I; Department of Biomedical and Chemical Engineering and Sciences, Florida Institute of Technology, Melbourne, FL 32937, USA., Higgins NR; Department of Biomedical and Chemical Engineering and Sciences, Florida Institute of Technology, Melbourne, FL 32937, USA., Lobo A; Department of Biomedical and Chemical Engineering and Sciences, Florida Institute of Technology, Melbourne, FL 32937, USA., Subasi MM; Department of Mathematical Sciences, Florida Institute of Technology, Melbourne, FL 32937, USA., Carroll DJ; Department of Biomedical and Chemical Engineering and Sciences, Florida Institute of Technology, Melbourne, FL 32937, USA., Turingan RG; Department of Ocean Engineering and Marine Sciences, Florida Institute of Technology, Melbourne, FL 32937, USA., Guisbert E; Department of Biomedical and Chemical Engineering and Sciences, Florida Institute of Technology, Melbourne, FL 32937, USA.

المصدر: The Journal of experimental biology [J Exp Biol] 2022 Mar 08; Vol. 225 (Suppl_1). Date of Electronic Publication: 2022 Mar 08.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 0243705 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9145 (Electronic) Linking ISSN: 00220949 NLM ISO Abbreviation: J Exp Biol Subsets: MEDLINE

مواضيع طبية MeSH: Perciformes*/physiology, Animals ; Aquaculture ; Fishes/genetics ; HSP70 Heat-Shock Proteins/genetics

المؤلفون: Higgins NR; Program in Molecular Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Center for Biomedical Engineering and Technology, Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, USA., Greenslade JE; Center for Biomedical Engineering and Technology, Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, USA., Wu JJ; Center for Biomedical Engineering and Technology, Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, USA., Miranda E; Department of Biology and Biotechnologies 'Charles Darwin', Pasteur Institute - Cenci Bolognetti Foundation, Sapienza University of Rome, Rome, Italy., Galliciotti G; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Monteiro MJ; Program in Molecular Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Center for Biomedical Engineering and Technology, Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, USA.

المصدر: Brain pathology (Zurich, Switzerland) [Brain Pathol] 2021 Sep; Vol. 31 (5), pp. e12948. Date of Electronic Publication: 2021 Mar 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: International Society of Neuropathology Country of Publication: Switzerland NLM ID: 9216781 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-3639 (Electronic) Linking ISSN: 10156305 NLM ISO Abbreviation: Brain Pathol Subsets: MEDLINE

مواضيع طبية MeSH: Adaptor Proteins, Signal Transducing/*metabolism , Amyotrophic Lateral Sclerosis/*genetics , Amyotrophic Lateral Sclerosis/*pathology , Autophagy-Related Proteins/*metabolism , Frontotemporal Dementia/*pathology , Serpins/*genetics, Adaptor Proteins, Signal Transducing/genetics ; Amyotrophic Lateral Sclerosis/metabolism ; Animals ; Autophagy-Related Proteins/genetics ; Disease Models, Animal ; Frontotemporal Dementia/genetics ; Frontotemporal Dementia/metabolism ; Mice, Inbred C57BL ; Mice, Transgenic ; Motor Neurons/metabolism ; Motor Neurons/pathology ; Serpins/metabolism ; Spinal Cord/pathology ; Mice

SCR Disease Name: Frontotemporal Dementia With Motor Neuron Disease

المؤلفون: Lin BC; Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Phung TH; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Higgins NR; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Program in Molecular Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Greenslade JE; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Prado MA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA., Finley D; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA., Karbowski M; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Program in Molecular Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Polster BM; Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Program in Molecular Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Department of Anesthesiology, Center for Shock, Trauma and Anesthesiology Research, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Monteiro MJ; Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Program in Molecular Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

المصدر: Human molecular genetics [Hum Mol Genet] 2021 Jun 17; Vol. 30 (13), pp. 1230-1246.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

مواضيع طبية MeSH: Mutation*, Adaptor Proteins, Signal Transducing/*genetics , Amyotrophic Lateral Sclerosis/*genetics , Autophagy-Related Proteins/*genetics , Frontotemporal Dementia/*genetics , Mitochondria/*genetics , Mitochondrial Proteins/*genetics, Animals ; Cell Line ; Disease Models, Animal ; HeLa Cells ; Humans ; Immunoblotting ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Microscopy, Electron, Transmission ; Mitochondria/metabolism ; Mitochondria/ultrastructure ; Mitochondrial Proteins/metabolism ; Oxygen Consumption/genetics ; Proteomics/methods ; Mice

المؤلفون: Wu JJ; Center for Biomedical Engineering and Technology, Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201., Cai A; Center for Biomedical Engineering and Technology, Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201., Greenslade JE; Center for Biomedical Engineering and Technology, Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201., Higgins NR; Center for Biomedical Engineering and Technology, Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201., Fan C; Center for Biomedical Engineering and Technology, Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201., Le NTT; Center for Biomedical Engineering and Technology, Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201., Tatman M; Center for Biomedical Engineering and Technology, Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201., Whiteley AM; Department of Cell Biology, Harvard Medical School, Boston, MA 02115., Prado MA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115., Dieriks BV; Department of Anatomy and Medical Imaging, University of Auckland, 1010 Auckland, New Zealand.; Centre for Brain Research, University of Auckland, 1010 Auckland, New Zealand., Curtis MA; Department of Anatomy and Medical Imaging, University of Auckland, 1010 Auckland, New Zealand.; Centre for Brain Research, University of Auckland, 1010 Auckland, New Zealand., Shaw CE; United Kingdom Dementia Research Institute, King's College London, WC2R 2LS London, United Kingdom.; Maurice Wohl Clinical Neuroscience Institute, King's College London, SE5 9RT London, United Kingdom.; Institute of Psychiatry, Psychology, and Neuroscience, King's College London, WC2R 2LS London, United Kingdom., Siddique T; Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611., Faull RLM; Department of Anatomy and Medical Imaging, University of Auckland, 1010 Auckland, New Zealand.; Centre for Brain Research, University of Auckland, 1010 Auckland, New Zealand., Scotter EL; Centre for Brain Research, University of Auckland, 1010 Auckland, New Zealand.; Department of Pharmacology and Clinical Pharmacology, University of Auckland, 1010 Auckland, New Zealand., Finley D; Department of Cell Biology, Harvard Medical School, Boston, MA 02115., Monteiro MJ; Center for Biomedical Engineering and Technology, Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201; monteiro@som.umaryland.edu.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jun 30; Vol. 117 (26), pp. 15230-15241. Date of Electronic Publication: 2020 Jun 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Adaptor Proteins, Signal Transducing/*metabolism , Amyotrophic Lateral Sclerosis/*genetics , Autophagosomes/*physiology , Autophagy/*genetics , Autophagy-Related Proteins/*metabolism , Dementia/*genetics, Adaptor Proteins, Signal Transducing/genetics ; Amyotrophic Lateral Sclerosis/metabolism ; Amyotrophic Lateral Sclerosis/pathology ; Animals ; Autophagy-Related Proteins/genetics ; Biomarkers/metabolism ; Cell Line ; Dementia/metabolism ; Dementia/pathology ; Genetic Predisposition to Disease ; Humans ; Hydrogen-Ion Concentration ; Lysosomal Membrane Proteins/genetics ; Lysosomal Membrane Proteins/metabolism ; Mice ; Mice, Transgenic ; Microtubule-Associated Proteins/genetics ; Microtubule-Associated Proteins/metabolism ; Mutation ; Protein Binding ; Sequestosome-1 Protein/genetics ; Sequestosome-1 Protein/metabolism ; Up-Regulation ; Vacuolar Proton-Translocating ATPases/genetics ; Vacuolar Proton-Translocating ATPases/metabolism