المؤلفون: Xu RG; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom., Tiede C; Astbury Centre for Structural Molecular Biology and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Calabrese AN; Astbury Centre for Structural Molecular Biology and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Cheah LT; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom., Adams TL; Astbury Centre for Structural Molecular Biology and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Gauer JS; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom., Hindle MS; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom.; Centre for Biomedical Science Research, School of Health, Leeds Beckett University, Leeds, United Kingdom., Webb BA; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom., Yates DM; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom., Slater A; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Duval C; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom., Naseem KM; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom., Herr AB; Division of Immunobiology and Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Tomlinson DC; Astbury Centre for Structural Molecular Biology and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Watson SP; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Ariëns RAS; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom.

المصدر: Blood advances [Blood Adv] 2024 Aug 13; Vol. 8 (15), pp. 3917-3928.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

مواضيع طبية MeSH: Platelet Membrane Glycoproteins*/metabolism , Platelet Membrane Glycoproteins*/chemistry , Protein Binding* , Blood Platelets*/metabolism , Platelet Aggregation*/drug effects , Protein Multimerization*, Humans ; Ligands ; Binding Sites ; Collagen/metabolism ; Collagen/chemistry ; Carrier Proteins ; Peptides

المؤلفون: Khalil JS; Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds LS2 9JT, UK., Law R; Hull York Medical School, University of Hull, Hull HU6 7EL, UK., Raslan Z; Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds LS2 9JT, UK., Cheah LT; Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds LS2 9JT, UK., Hindle MS; Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds LS2 9JT, UK., Aburima AA; Hull York Medical School, University of Hull, Hull HU6 7EL, UK., Kearney MT; Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds LS2 9JT, UK., Naseem KM; Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds LS2 9JT, UK.

المصدر: Cells [Cells] 2024 Jun 26; Vol. 13 (13). Date of Electronic Publication: 2024 Jun 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

مواضيع طبية MeSH: Cyclic Nucleotide Phosphodiesterases, Type 3*/metabolism , Cyclic Nucleotide Phosphodiesterases, Type 3*/genetics , Blood Platelets*/metabolism , Blood Platelets*/drug effects , A Kinase Anchor Proteins*/metabolism , Cyclic AMP-Dependent Protein Kinases*/metabolism , Epoprostenol*/metabolism , Epoprostenol*/pharmacology, Humans ; Phosphorylation ; Cyclic AMP/metabolism ; Signal Transduction

المؤلفون: Khalil J; School of Physiology, Pharmacology and Neuroscience, Faculty of Life Sciences, University of Bristol, Bristol, UK., Dimofte T; School of Physiology, Pharmacology and Neuroscience, Faculty of Life Sciences, University of Bristol, Bristol, UK., Roberts T; School of Physiology, Pharmacology and Neuroscience, Faculty of Life Sciences, University of Bristol, Bristol, UK., Keith M; School of Physiology, Pharmacology and Neuroscience, Faculty of Life Sciences, University of Bristol, Bristol, UK., Amaradasa K; School of Physiology, Pharmacology and Neuroscience, Faculty of Life Sciences, University of Bristol, Bristol, UK., Hindle MS; Leeds Institute of Genetics, Health and Therapeutics (LIGHT), University of Leeds, Leeds, UK., Bancroft S; School of Physiology, Pharmacology and Neuroscience, Faculty of Life Sciences, University of Bristol, Bristol, UK., Hutchinson JL; School of Physiology, Pharmacology and Neuroscience, Faculty of Life Sciences, University of Bristol, Bristol, UK., Naseem K; Leeds Institute of Genetics, Health and Therapeutics (LIGHT), University of Leeds, Leeds, UK., Johnson T; Bristol Medical School, University of Bristol, Bristol, UK., Mundell SJ; School of Physiology, Pharmacology and Neuroscience, Faculty of Life Sciences, University of Bristol, Bristol, UK.

المصدر: British journal of pharmacology [Br J Pharmacol] 2024 Jan; Vol. 181 (1), pp. 21-35. Date of Electronic Publication: 2023 Sep 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Diphosphates*/metabolism , Diphosphates*/pharmacology , Diphosphates*/therapeutic use , Acute Coronary Syndrome*/drug therapy , Acute Coronary Syndrome*/complications, Humans ; Ticagrelor/pharmacology ; Ticagrelor/metabolism ; Ticagrelor/therapeutic use ; Adenosine/pharmacology ; Drug Inverse Agonism ; Purinergic P2Y Receptor Antagonists/pharmacology ; Platelet Aggregation Inhibitors/pharmacology ; Adenosine Diphosphate/pharmacology ; Adenosine Diphosphate/metabolism ; Blood Platelets ; Receptors, Purinergic P2Y12/metabolism

المؤلفون: Berger M; Department of Internal Medicine I, University Hospital Aachen, Aachen, Germany., Maqua H; Department of Internal Medicine I, University Hospital Aachen, Aachen, Germany., Lysaja K; Department of Internal Medicine I, University Hospital Aachen, Aachen, Germany., Mause SF; Department of Internal Medicine I, University Hospital Aachen, Aachen, Germany., Hindle MS; Centre for Biomedical Research, School of Health, Leeds Beckett University, Leeds, UK., Naseem K; Discovery and Translational Science Department, Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds, UK., Dahl E; Rheinisch Westfälische Technische Hochschule Centralized Biomaterial Bank, University Hospital Aachen, Aachen, Germany., Speer T; Department of Internal Medicine IV, Goethe University Frankfurt, Frankfurt am Main, Germany.; Else Kroener Fresenius Center for Nephrological Research, Goethe University Frankfurt, Frankfurt am Main, Germany., Marx N; Department of Internal Medicine I, University Hospital Aachen, Aachen, Germany., Schütt K; Department of Internal Medicine I, University Hospital Aachen, Aachen, Germany.

المصدر: Research and practice in thrombosis and haemostasis [Res Pract Thromb Haemost] 2023 Nov 14; Vol. 8 (1), pp. 102261. Date of Electronic Publication: 2023 Nov 14 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101703775 Publication Model: eCollection Cited Medium: Internet ISSN: 2475-0379 (Electronic) Linking ISSN: 24750379 NLM ISO Abbreviation: Res Pract Thromb Haemost Subsets: PubMed not MEDLINE

المؤلفون: Hindle MS; Discovery and Translational Science Department, Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, UK.; Centre for Biomedical Science Research, School of Health, Leeds Beckett University, UK., Cheah LT; Discovery and Translational Science Department, Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, UK., Yates DM; Discovery and Translational Science Department, Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, UK., Naseem KM; Discovery and Translational Science Department, Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, UK.

المصدر: Research and practice in thrombosis and haemostasis [Res Pract Thromb Haemost] 2023 Sep 20; Vol. 7 (7), pp. 102205. Date of Electronic Publication: 2023 Sep 20 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101703775 Publication Model: eCollection Cited Medium: Internet ISSN: 2475-0379 (Electronic) Linking ISSN: 24750379 NLM ISO Abbreviation: Res Pract Thromb Haemost Subsets: PubMed not MEDLINE

المؤلفون: McPherson HR; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom., Duval C; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom., Baker SR; Department of Physics, Wake Forest University, Winston Salem, United States., Hindle MS; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom., Cheah LT; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom., Asquith NL; Division of Hematology, Brigham and Women's Hospital, Harvard Medical School, Boston, United States., Domingues MM; Instituto de Medicina Molecular - João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., Ridger VC; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom., Connell SD; Molecular and Nanoscale Physics Group, University of Leeds, Leeds, United Kingdom., Naseem KM; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom., Philippou H; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom., Ajjan RA; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom., Ariëns RA; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom.

المصدر: ELife [Elife] 2021 Oct 11; Vol. 10. Date of Electronic Publication: 2021 Oct 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Fibrinolysis*, Blood Coagulation/*physiology , Fibrinogen/*chemistry , Fibrinogen/*metabolism , Peptide Fragments/*chemistry , Peptide Fragments/*metabolism, Animals ; CHO Cells ; Cricetulus ; Fibrin/chemistry ; Humans ; Mice, Knockout ; Recombinant Proteins/chemistry ; Mice

المؤلفون: Hindle MS; Discovery and Translational Science Department, Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds, UK., Spurgeon BEJ; Discovery and Translational Science Department, Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds, UK., Cheah LT; Discovery and Translational Science Department, Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds, UK., Webb BA; Discovery and Translational Science Department, Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds, UK., Naseem KM; Discovery and Translational Science Department, Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds, UK.

المصدر: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2021 Jul; Vol. 19 (7), pp. 1800-1812. Date of Electronic Publication: 2021 Apr 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7836 (Electronic) Linking ISSN: 15387836 NLM ISO Abbreviation: J Thromb Haemost Subsets: MEDLINE

مواضيع طبية MeSH: Blood Platelets* , Epoprostenol*, Flow Cytometry ; Humans ; Platelet Activation ; Platelet Aggregation

المؤلفون: Berger M; Centre for Cardiovascular and Metabolic Research, Hull York Medical School, University of Hull, Hull, UK.; Department of Internal Medicine 1, University Hospital RWTH Aachen, Aachen, Germany.; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK., Raslan Z; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK., Aburima A; Centre for Cardiovascular and Metabolic Research, Hull York Medical School, University of Hull, Hull, UK., Magwenzi S; Centre for Cardiovascular and Metabolic Research, Hull York Medical School, University of Hull, Hull, UK., Wraith KS; Centre for Cardiovascular and Metabolic Research, Hull York Medical School, University of Hull, Hull, UK., Spurgeon BEJ; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK., Hindle MS; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK., Law R; Centre for Cardiovascular and Metabolic Research, Hull York Medical School, University of Hull, Hull, UK., Febbraio M; School of Dentistry, University of Alberta, Edmonton, AB, Canada., Naseem KM; Centre for Cardiovascular and Metabolic Research, Hull York Medical School, University of Hull, Hull, UK k.naseem@leeds.ac.uk.; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.

المصدر: Haematologica [Haematologica] 2020 Mar; Vol. 105 (3), pp. 808-819. Date of Electronic Publication: 2019 Jul 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1592-8721 (Electronic) Linking ISSN: 03906078 NLM ISO Abbreviation: Haematologica Subsets: MEDLINE

مواضيع طبية MeSH: Blood Platelets* , Epoprostenol*, Animals ; Cyclic Nucleotide Phosphodiesterases, Type 3/genetics ; Humans ; Lipids ; Mice ; Platelet Activation ; Platelet Aggregation

المؤلفون: Berger M; a Centre for Atherothrombosis and Metabolic Disease, Hull-York Medical School , Faculty of Health Sciences, University of Hull , Hull , UK.; c Department of Internal Medicine 1 , University Hospital RWTH Aachen , Aachen , Germany., Wraith K; a Centre for Atherothrombosis and Metabolic Disease, Hull-York Medical School , Faculty of Health Sciences, University of Hull , Hull , UK., Woodward C; a Centre for Atherothrombosis and Metabolic Disease, Hull-York Medical School , Faculty of Health Sciences, University of Hull , Hull , UK., Aburima A; a Centre for Atherothrombosis and Metabolic Disease, Hull-York Medical School , Faculty of Health Sciences, University of Hull , Hull , UK., Raslan Z; b Leeds Institute of Cardiovascular & Metabolic Medicine , The LIGHT Laboratories, University of Leeds , Leeds , UK., Hindle MS; b Leeds Institute of Cardiovascular & Metabolic Medicine , The LIGHT Laboratories, University of Leeds , Leeds , UK., Moellmann J; c Department of Internal Medicine 1 , University Hospital RWTH Aachen , Aachen , Germany., Febbraio M; d School of Dentistry , University of Alberta , Edmonton , AB , Canada., Naseem KM; b Leeds Institute of Cardiovascular & Metabolic Medicine , The LIGHT Laboratories, University of Leeds , Leeds , UK.

المصدر: Platelets [Platelets] 2019; Vol. 30 (4), pp. 467-472. Date of Electronic Publication: 2018 May 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9208117 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1369-1635 (Electronic) Linking ISSN: 09537104 NLM ISO Abbreviation: Platelets Subsets: MEDLINE

مواضيع طبية MeSH: Dyslipidemias/*diagnosis , Dyslipidemias/*genetics , Lipoproteins, LDL/*metabolism , Phospholipase C gamma/*metabolism , Platelet Activation/*genetics, Animals ; Dyslipidemias/pathology ; Humans ; Mice ; Reactive Oxygen Species