المؤلفون: Phua Qh, Koh Jl, Si Yun Ng, Yu Zong Chen, Pang J, Liew Lc, Yan Ping Loh, Seshachalam Vp, Boon Seng Soh, Ho Bx, Omer An, Chan W, Henry Yang, Poh Bm

مصطلحات موضوعية: Transcriptome, medicine.anatomical_structure, Ejection fraction, Cell type composition, In vivo, business.industry, Cardiac hypertrophy, Cell, Organoid, medicine, Induced pluripotent stem cell, business, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fb4d54ce28204e542b78f586eb73e2ca
https://doi.org/10.1101/2021.05.21.445153

المؤلفون: Sokrat B; Department of Biochemistry and Molecular Medicine, University of Montreal, Montreal, QC, H3T 1J4, Canada.; Institute for Research in Immunology and Cancer, University of Montreal, Montreal, QC, H3T 1J4, Canada.; Department of Molecular Pathobiology, New York University School of Dentistry, New York, NY, 10010, USA., Nguyen AH; Department of Biochemistry, Duke University School of Medicine, Durham, NC, 27710, USA., Thomsen ARB; Department of Biochemistry, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Medicine, Duke University Medical Center, Durham, NC, 27710, USA.; Department of Molecular Pathobiology, New York University School of Dentistry, New York, NY, 10010, USA., Huang LY; Department of Biochemistry, Duke University School of Medicine, Durham, NC, 27710, USA., Kobayashi H; Institute for Research in Immunology and Cancer, University of Montreal, Montreal, QC, H3T 1J4, Canada., Kahsai AW; Department of Medicine, Duke University Medical Center, Durham, NC, 27710, USA., Kim J; Department of Biochemistry, Duke University School of Medicine, Durham, NC, 27710, USA., Ho BX; Department of Biochemistry, Duke University School of Medicine, Durham, NC, 27710, USA., Ma S; Department of Biochemistry, Duke University School of Medicine, Durham, NC, 27710, USA., Little J 4th; Department of Biochemistry, Duke University School of Medicine, Durham, NC, 27710, USA., Ehrhart C; Department of Biochemistry, Duke University School of Medicine, Durham, NC, 27710, USA., Pyne I; Department of Biochemistry, Duke University School of Medicine, Durham, NC, 27710, USA., Hammond E; Department of Biochemistry, Duke University School of Medicine, Durham, NC, 27710, USA., Bouvier M; Department of Biochemistry and Molecular Medicine, University of Montreal, Montreal, QC, H3T 1J4, Canada. michel.bouvier@umontreal.ca.; Institute for Research in Immunology and Cancer, University of Montreal, Montreal, QC, H3T 1J4, Canada. michel.bouvier@umontreal.ca.

المصدر: Communications biology [Commun Biol] 2024 Jul 07; Vol. 7 (1), pp. 826. Date of Electronic Publication: 2024 Jul 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

مواضيع طبية MeSH: beta-Arrestins*/metabolism , Endosomes*/metabolism , GTP-Binding Protein beta Subunits*/metabolism , GTP-Binding Protein beta Subunits*/genetics , GTP-Binding Protein gamma Subunits*/metabolism , GTP-Binding Protein gamma Subunits*/genetics , Protein Transport* , Receptors, Vasopressin*/metabolism , Receptors, Vasopressin*/genetics, Humans ; Cell Membrane/metabolism ; HEK293 Cells ; Signal Transduction

المؤلفون: Ho BX; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; BetaLife Pte Ltd, Singapore, Singapore., Teo AKK; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Precision Medicine Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Ng NHJ; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

المصدر: Frontiers in immunology [Front Immunol] 2024 Apr 08; Vol. 15, pp. 1375177. Date of Electronic Publication: 2024 Apr 08 (Print Publication: 2024).

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Islets of Langerhans Transplantation*/methods , Diabetes Mellitus, Type 1*/immunology , Diabetes Mellitus, Type 1*/therapy , Graft Rejection*/immunology , Graft Rejection*/prevention & control, Humans ; Animals ; Biomedical Engineering/methods ; Islets of Langerhans/immunology

المؤلفون: Liew LC; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore, 138673, Republic of Singapore., Poh BM; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore, 138673, Republic of Singapore., An O; Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Republic of Singapore., Ho BX; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore, 138673, Republic of Singapore., Lim CYY; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore, 138673, Republic of Singapore., Pang JKS; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore, 138673, Republic of Singapore., Beh LY; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore, 138673, Republic of Singapore., Yang HH; Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Republic of Singapore., Soh BS; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore, 138673, Republic of Singapore. bssoh@imcb.a-star.edu.sg.; Department of Biological Sciences, National University of Singapore, Singapore, 117543, Republic of Singapore. bssoh@imcb.a-star.edu.sg.

المصدر: Stem cell research & therapy [Stem Cell Res Ther] 2023 Dec 13; Vol. 14 (1), pp. 367. Date of Electronic Publication: 2023 Dec 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE

مواضيع طبية MeSH: Pluripotent Stem Cells* , Induced Pluripotent Stem Cells*/metabolism, Humans ; Myocytes, Cardiac/metabolism ; Janus Kinase 2/genetics ; Janus Kinase 2/metabolism ; Janus Kinase 2/pharmacology ; Calcium/metabolism ; Cell Differentiation

المؤلفون: Ho BX; Disease Modelling and Therapeutics Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive Proteos, Singapore, 138673, Singapore.; Department of Biological Sciences, National University of Singapore, 16 Science Drive 4, Singapore, 117543, Singapore., Pang JKS; Disease Modelling and Therapeutics Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive Proteos, Singapore, 138673, Singapore.; Department of Biological Sciences, National University of Singapore, 16 Science Drive 4, Singapore, 117543, Singapore., Chen Y; Department of Biological Sciences, National University of Singapore, 16 Science Drive 4, Singapore, 117543, Singapore.; Integrative Sciences and Engineering Programme, National University of Singapore, 21 Lower Kent Ridge Road, Singapore, 119077, Singapore.; Epigenetics and Cell Fates Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive Proteos, Singapore, 138673, Singapore., Loh YH; Department of Biological Sciences, National University of Singapore, 16 Science Drive 4, Singapore, 117543, Singapore.; Epigenetics and Cell Fates Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive Proteos, Singapore, 138673, Singapore., An O; Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, Singapore, 117599, Singapore., Yang HH; Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, Singapore, 117599, Singapore., Seshachalam VP; Computational Phenomics Group, Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), Singapore, 138670, Singapore., Koh JLY; Computational Phenomics Group, Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), Singapore, 138670, Singapore., Chan WK; Department of Biological Sciences, National University of Singapore, 16 Science Drive 4, Singapore, 117543, Singapore., Ng SY; Neurotherapeutics Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive Proteos, Singapore, 138673, Singapore. syng@imcb.a-star.edu.sg.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, 10 Medical Drive, Singapore, 117456, Singapore. syng@imcb.a-star.edu.sg.; National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore. syng@imcb.a-star.edu.sg., Soh BS; Disease Modelling and Therapeutics Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive Proteos, Singapore, 138673, Singapore. bssoh@imcb.a-star.edu.sg.; Department of Biological Sciences, National University of Singapore, 16 Science Drive 4, Singapore, 117543, Singapore. bssoh@imcb.a-star.edu.sg.

المصدر: Stem cell research & therapy [Stem Cell Res Ther] 2022 Dec 21; Vol. 13 (1), pp. 529. Date of Electronic Publication: 2022 Dec 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE

مواضيع طبية MeSH: Cardiovascular Diseases*/metabolism , Pluripotent Stem Cells* , Induced Pluripotent Stem Cells*/metabolism, Humans ; Calcium/metabolism ; Organoids/metabolism ; Cell Differentiation/physiology ; Myocytes, Cardiac/metabolism ; Cardiomegaly/metabolism

المؤلفون: Ho BX; Disease Modeling and Therapeutics Laboratory, A(∗)STAR Institute of Molecular and Cell Biology, 61 Biopolis Drive Proteos, Singapore 138673, Singapore; Department of Biological Sciences, National University of Singapore, Singapore 117543, Singapore., Yu H; Disease Modeling and Therapeutics Laboratory, A(∗)STAR Institute of Molecular and Cell Biology, 61 Biopolis Drive Proteos, Singapore 138673, Singapore., Pang JKS; Disease Modeling and Therapeutics Laboratory, A(∗)STAR Institute of Molecular and Cell Biology, 61 Biopolis Drive Proteos, Singapore 138673, Singapore; Department of Biological Sciences, National University of Singapore, Singapore 117543, Singapore., Hor JH; Neurotherapeutics Laboratory, A(∗)STAR Institute of Molecular and Cell Biology, 61 Biopolis Drive Proteos, Singapore 138673, Singapore., Liew LC; Disease Modeling and Therapeutics Laboratory, A(∗)STAR Institute of Molecular and Cell Biology, 61 Biopolis Drive Proteos, Singapore 138673, Singapore., Szyniarowski P; A∗STAR Skin Research Labs, 8A Biomedical Grove #06-40, Immunos, Singapore 138648., Lim CYY; Disease Modeling and Therapeutics Laboratory, A(∗)STAR Institute of Molecular and Cell Biology, 61 Biopolis Drive Proteos, Singapore 138673, Singapore., An O; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore., Yang HH; Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore., Stewart CL; A∗STAR Skin Research Labs, 8A Biomedical Grove #06-40, Immunos, Singapore 138648., Chan WK; Department of Biological Sciences, National University of Singapore, Singapore 117543, Singapore., Ng SY; Neurotherapeutics Laboratory, A(∗)STAR Institute of Molecular and Cell Biology, 61 Biopolis Drive Proteos, Singapore 138673, Singapore; Department of Physiology, National University of Singapore, 2 Medical Dr, Singapore 117593, Singapore; National Neuroscience Institute, Singapore 308433, Singapore. Electronic address: syng@imcb.a-star.edu.sg., Soh BS; Disease Modeling and Therapeutics Laboratory, A(∗)STAR Institute of Molecular and Cell Biology, 61 Biopolis Drive Proteos, Singapore 138673, Singapore; Department of Biological Sciences, National University of Singapore, Singapore 117543, Singapore. Electronic address: bssoh@imcb.a-star.edu.sg.

المصدر: Stem cell reports [Stem Cell Reports] 2021 Dec 14; Vol. 16 (12), pp. 2928-2941. Date of Electronic Publication: 2021 Nov 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE

مواضيع طبية MeSH: Cell Differentiation*/drug effects , Signal Transduction*/drug effects , Up-Regulation*/drug effects, Human Embryonic Stem Cells/*cytology , Human Embryonic Stem Cells/*metabolism , Janus Kinases/*metabolism , Myocytes, Cardiac/*cytology , STAT Transcription Factors/*metabolism, CRISPR-Cas Systems/genetics ; Cell Line ; Electrophysiological Phenomena/drug effects ; Genes, Reporter ; Green Fluorescent Proteins/metabolism ; Human Embryonic Stem Cells/drug effects ; Humans ; Interferon-gamma/metabolism ; Interferon-gamma/pharmacology

المؤلفون: Pang JKS; Disease Modeling and Therapeutics Laboratory, ASTAR Institute of Molecular and Cell Biology, Singapore, Singapore.; Department of Biological Sciences, National University of Singapore, Singapore, Singapore., Ho BX; Disease Modeling and Therapeutics Laboratory, ASTAR Institute of Molecular and Cell Biology, Singapore, Singapore.; Department of Biological Sciences, National University of Singapore, Singapore, Singapore., Chan WK; Department of Biological Sciences, National University of Singapore, Singapore, Singapore., Soh BS; Disease Modeling and Therapeutics Laboratory, ASTAR Institute of Molecular and Cell Biology, Singapore, Singapore.; Department of Biological Sciences, National University of Singapore, Singapore, Singapore.

المصدر: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2021 Dec 02; Vol. 9, pp. 788955. Date of Electronic Publication: 2021 Dec 02 (Print Publication: 2021).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE

المؤلفون: Hor JH; Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore, 138673, Singapore.; Department of Biological Sciences, National University of Singapore, Singapore, 117543, Singapore., Santosa MM; Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore, 138673, Singapore.; Yong Loo Lin School of Medicine (Physiology), National University of Singapore, Singapore, 117456, Singapore., Lim VJW; Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore, 138673, Singapore., Ho BX; Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore, 138673, Singapore.; Department of Biological Sciences, National University of Singapore, Singapore, 117543, Singapore., Taylor A; Department of Neurosciences, University of California, San Diego, CA, USA., Khong ZJ; Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore, 138673, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, 637551, Singapore., Ravits J; Department of Neurosciences, University of California, San Diego, CA, USA., Fan Y; The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China., Liou YC; Department of Biological Sciences, National University of Singapore, Singapore, 117543, Singapore., Soh BS; Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore, 138673, Singapore. bssoh@imcb.a-star.edu.sg.; Department of Biological Sciences, National University of Singapore, Singapore, 117543, Singapore. bssoh@imcb.a-star.edu.sg.; The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China. bssoh@imcb.a-star.edu.sg., Ng SY; Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore, 138673, Singapore. syng@imcb.a-star.edu.sg.; Yong Loo Lin School of Medicine (Physiology), National University of Singapore, Singapore, 117456, Singapore. syng@imcb.a-star.edu.sg.; The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China. syng@imcb.a-star.edu.sg.; National Neuroscience Institute, Singapore, 308433, Singapore. syng@imcb.a-star.edu.sg.

المصدر: Cell death and differentiation [Cell Death Differ] 2021 Apr; Vol. 28 (4), pp. 1379-1397. Date of Electronic Publication: 2020 Nov 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5403 (Electronic) Linking ISSN: 13509047 NLM ISO Abbreviation: Cell Death Differ Subsets: MEDLINE

مواضيع طبية MeSH: Amyotrophic Lateral Sclerosis/*genetics , Amyotrophic Lateral Sclerosis/*pathology , Motor Neurons/*metabolism , Motor Neurons/*pathology , Sirtuin 3/*genetics, Animals ; Cell Differentiation ; Humans ; Induced Pluripotent Stem Cells/metabolism ; Mice ; Mitochondria/metabolism ; Mitochondria/ultrastructure ; Motor Neurons/ultrastructure ; Sirtuin 3/metabolism

المؤلفون: Liew LC; Disease Modeling and Therapeutics Laboratory, A*STAR Institute of Molecular and Cell Biology, 61 Biopolis Drive Proteos, Singapore, 138673, Singapore., Ho BX; Disease Modeling and Therapeutics Laboratory, A*STAR Institute of Molecular and Cell Biology, 61 Biopolis Drive Proteos, Singapore, 138673, Singapore.; Department of Biological Sciences, National University of Singapore, Singapore, 117543, Singapore., Soh BS; Disease Modeling and Therapeutics Laboratory, A*STAR Institute of Molecular and Cell Biology, 61 Biopolis Drive Proteos, Singapore, 138673, Singapore. bssoh@imcb.a-star.edu.sg.; Department of Biological Sciences, National University of Singapore, Singapore, 117543, Singapore. bssoh@imcb.a-star.edu.sg.; Key Laboratory for Major Obstetric Diseases of Guangdong Province, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China. bssoh@imcb.a-star.edu.sg.

المصدر: Stem cell research & therapy [Stem Cell Res Ther] 2020 Mar 26; Vol. 11 (1), pp. 138. Date of Electronic Publication: 2020 Mar 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE

مواضيع طبية MeSH: Myocardial Ischemia* , Pluripotent Stem Cells*, Cell- and Tissue-Based Therapy ; Humans ; Myocytes, Cardiac ; Regenerative Medicine

المؤلفون: Lu HS; Global Health Research Center, Duke Kunshan University, Kunshan, Jiangsu, China., Ho BX; Trinity College for Arts & Sciences, Duke University, Durham, NC, USA., Miranda JJ; CRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.; School of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru.

المصدر: International journal of health policy and management [Int J Health Policy Manag] 2020 Mar 01; Vol. 9 (3), pp. 128-132. Date of Electronic Publication: 2020 Mar 01.

نوع المنشور: Journal Article; Comment

بيانات الدورية: Publisher: Kerman University of Medical Sciences Country of Publication: Iran NLM ID: 101619905 Publication Model: Electronic Cited Medium: Internet ISSN: 2322-5939 (Electronic) Linking ISSN: 23225939 NLM ISO Abbreviation: Int J Health Policy Manag Subsets: MEDLINE

مواضيع طبية MeSH: Government Programs* , Health Care Sector*, Global Health ; Humans ; Peru ; Universal Health Insurance